uracil and thiouracil

uracil has been researched along with thiouracil in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-199048 (61.54)18.7374
1990's4 (5.13)18.2507
2000's11 (14.10)29.6817
2010's12 (15.38)24.3611
2020's3 (3.85)2.80

Authors

AuthorsStudies
Belser, WL; O'Donovan, GA; Wild, JR1
Hillerbrand, M; Lohmann, W; Wenzl, H1
Beck, CF; Howlett, GJ1
Ralph, RK; Wojcik, SJ1
de Nardo, M; Dolfini, E; Fabrissin, S; Franchi, G; Morasca, L; Nisi, C1
Baba, M; De Clercq, E; Miyasaka, T; Pauwels, R; Shigeta, S; Tanaka, H; Ubasawa, M; Umezu, K; Walker, RT1
Manuel de Gandarias, J; Martinez, A; Zatón, A1
Ochoa de Aspuru, E; Zaton, A1
Van Middlesworth, L1
Van de Vorst, A1
Lindsay, RH; Yu, MW1
Bauernfeind, A; Grümmer, G1
Golovinsky, E; Maneva, L; Spassov, A; Spassovska, N1
Kulakowska, I; Rabczenko, A1
Bergstrom, DE; Leonard, NJ1
Ashworth, TS; Brown, EG; Roberts, FM1
Lohmann, W; Penka, V1
Cardeilhac, PT1
Timson, J1
Dawson, WO; Kuhn, CW1
Winkley, MW1
Falco, EA; Fox, JJ1
Lindsay, RH; Romine, CJ; Wong, MY1
Matolcsy, G1
Thiry, L1
Beridze, TG; Cherkashina, NA; Odintsova, MS; Sisakian, NM1
Akimov, AA; Lazarev, NV1
Gibbs, AJ; Hecht-Poinar, E; McKee, RK; Woods, RD1
Dubash, PJ; Rege, DV1
Bunker, JE; Keller, F; Tyrrill, AR1
Harada, F; Miura, K; Tsuda, S; Ueda, T1
Arenhövel, C; Schuster, G1
Ochoa de Aspuru, E; Zatón, AM1
Iltzsch, MH; Klenk, EE1
Danel, K; Nielsen, C; Pedersen, EB1
Barontini, S; Bertini, S; Danesi, R; Di Bussolo, V; Fogli, S; Giovannetti, E; Grossi, E; Macchia, M; Minutolo, F1
Palafox, MA; Rastogi, VK1
BER, A1
KEPLINGER, ML; WENZEL, DG1
POE, CF; PULESTON, HS; WITT, NF1
MALOOF, F; SOODAK, M1
ANDRUS, SB; FILLIOS, LC; NAITO, C; ROACH, AM1
BAUERNFEIND, A; LEDOUX, L1
JEFFREY, JJ; SCHANKER, LS1
BEN-ISHAI, R; LAHAV, M; ZAMIR, A1
COHEN, PP; LINDSAY, RH; NAKAGAWA, H1
COHEN, PP; LINDSAY, RH1
KELEMEN, MH; VOLLE, RL1
Alcamí, M; Lamsabhi, AM; Mó, O; Yáñez, M1
Andrei, G; Balzarini, J; De Clercq, E; Kozai, S; Maruyama, T; Pannecouque, C; Snoeck, R; Witvrouw, M; Yamasaki, T1
KARLIN, R; WOLFF, R1
CANTAROW, A; PASCHKIS, KE; STASNEY, J1
STERBA, G1
Alcamí, M; Lamsabhi, AM; Mó, O; Tortajada, J; Yáñez, M2
Al Safarjalani, ON; El Kouni, MH; Naguib, FN; Rais, RH; Schinazi, RF; Shi, J; Zhou, XJ1
Harinipriya, S; Sangaranarayanan, MV1
El-Marghany, A; Ibrahim, AA; Khalil, EA; Masoud, MS1
Nizet, A1
TROTTER, WR1
Gutiérrez-Oliva, S; Lamsabhi, AM; Mó, O; Pérez, P; Toro-Labbé, A; Yáñez, M1
Boudet, N; Knochel, P; Mosrin, M1
Jaiswal, S; Kumar, M; Singh, P; Singh, R; Srivastav, G; Yadav, RA1
CULLUMBINE, H; SIMPSON, M1
Abdel-Aal, MT1
Boyd, RJ; Eizaguirre, A; Mó, O; Yáñez, M1
Gronert, S; Huang, S; Wu, W1
Elferich, J; Forquer, I; Riscoe, MK; Shinde, U; Soysa, R; Ullman, B; Wilson, ZN; Yates, PA1
Egert, E; Hützler, WM1
Acres, RG; Cassidy, A; Feyer, V; Lyamayev, V; Plekan, O; Prince, KC; Ptasińska, S; Reiff, S; Tsud, N1
Bolte, M; Hützler, WM; Seiler, VK1
Aučynaitė, A; Gasparavičiūtė, R; Meškys, R; Rutkienė, R; Urbonavičius, J1
Krishna, BA; Murphy, EA; Nukui, M; O'Connor, CM; Roche, KL1
Ali, SA; Awad, SM; Mahgoub, S; Said, AM; Zohny, YM1
Freddolino, PL; Goldstrohm, AC; Wolfe, MB1
Kulik, K; Nawrot, B; Pacholczyk-Sienicka, B; Sadowska, K; Sochacka, E; Wielgus, E1
Asplund, M; Koga, M; Neumark, DM1
El-Kalyoubi, S; Elbaramawi, SS; Ibrahim, TS; Malebari, AM; Safo, MK; Taher, ES; Zordok, WA1

Reviews

2 review(s) available for uracil and thiouracil

ArticleYear
Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4-Positive T-Lymphocytes; Drug Combinations; HIV Reverse Transcriptase; HIV-1; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiouracil; Uracil

1992
Global analysis of RNA metabolism using bio-orthogonal labeling coupled with next-generation RNA sequencing.
    Methods (San Diego, Calif.), 2019, 02-15, Volume: 155

    Topics: Animals; Biotin; Bromouracil; Cell Line; Click Chemistry; High-Throughput Nucleotide Sequencing; Humans; RNA Stability; RNA, Messenger; Staining and Labeling; Thiouracil; Thiouridine; Transcriptome; Uracil; Uridine

2019

Other Studies

76 other study(ies) available for uracil and thiouracil

ArticleYear
Unique aspects of the regulation of the aspartate transcarbamylase of Serratia marcescens.
    Journal of bacteriology, 1976, Volume: 128, Issue:3

    Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Cytosine Nucleotides; Enzyme Activation; Enzyme Repression; Guanine Nucleotides; Heart; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Serratia marcescens; Thiouracil; Uracil; Uracil Nucleotides

1976
Charge-transfer interactions between metal ions and some uracil derivatives.
    Biophysics of structure and mechanism, 1975, Feb-19, Volume: 1, Issue:2

    Topics: Copper; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Methylthiouracil; Spectrophotometry; Thiouracil; Uracil

1975
The nature of the miscoding caused by growth in the presence of 2-thiouracil.
    Journal of molecular biology, 1977, Mar-25, Volume: 111, Issue:1

    Topics: Bacterial Proteins; Codon; Escherichia coli; Fluorouracil; Mutation; Phenotype; RNA, Bacterial; RNA, Messenger; Salmonella typhimurium; Thiouracil; Uracil

1977
Inhibition of turnip yellow mosaic virus synthesis by pyrimidine analogues.
    Biochimica et biophysica acta, 1976, Aug-24, Volume: 444, Issue:1

    Topics: Azauridine; Mosaic Viruses; Phosphates; Plant Viruses; RNA; Thiouracil; Thiouridine; Uracil; Uracil Nucleotides; Uridine; Viral Proteins; Virus Replication

1976
Synthesis and anticancer activity of 5-diethylaminomethyl derivatives and nitrogen mustards of uracil and 2-thiouracils.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:5

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Humans; Mice; Mouth Neoplasms; Nitrogen Mustard Compounds; Thiouracil; Uracil

1976
The binding of thioureylene compounds to human serum albumin.
    Biochemical pharmacology, 1988, Aug-15, Volume: 37, Issue:16

    Topics: Antithyroid Agents; Diazepam; Humans; Propylthiouracil; Serum Albumin; Spectrophotometry, Ultraviolet; Thiouracil; Uracil; Warfarin

1988
Interaction of propylthiouracil and its precursors with horseradish peroxidase.
    Biochemical and biophysical research communications, 1988, Jun-30, Volume: 153, Issue:3

    Topics: Horseradish Peroxidase; Peroxidases; Propylthiouracil; Protein Conformation; Spectrophotometry; Thiouracil; Uracil; Viscosity

1988
Failure to confirm goitrogenic and hypercholesterolemic effects of uracil.
    Endocrinology, 1965, Volume: 77, Issue:5

    Topics: Animals; Antithyroid Agents; Cholesterol; Chromatography, Paper; Organ Size; Rats; Thiouracil; Thyroid Gland; Thyroxine; Uracil; Urine

1965
H-adduct radicals in x-irradiated frozen solutions of uracil derivatives.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1973, Volume: 24, Issue:1

    Topics: Deoxyuridine; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Radiation Effects; Thiouracil; Uracil

1973
Inhibitory effects of 2-thiouracil and 2-thiouracil metabolites on enzymes involved in pyrimidine nucleotide biosynthesis.
    Biochemical pharmacology, 1974, Aug-15, Volume: 23, Issue:16

    Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; In Vitro Techniques; Kinetics; Mice; Nucleotidyltransferases; Orotic Acid; Pentosyltransferases; Phosphotransferases; Proteins; Pyrimidines; Rats; Thiouracil; Thymidine; Thymine; Uracil; Uracil Nucleotides; Uridine

1974
The splitting of 2-thiouracil by a pyrimidineless Escherichia coli.
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1968, Volume: 23, Issue:4

    Topics: Escherichia coli; Genetics, Microbial; Molecular Biology; Mutation; Phenols; Sulfur Isotopes; Thiouracil; Uracil

1968
Effect of thio- and hydrazino-derivatives of uracil, 6-azauracil and 6-azathymine on the growth of some microorganisms in vitro.
    Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie, 1972, Volume: 27, Issue:7

    Topics: Aza Compounds; Bacillus subtilis; Candida; Drug Resistance, Microbial; Enterococcus faecalis; Escherichia coli; Hydrazines; Microbial Sensitivity Tests; Neurospora crassa; Pseudomonas aeruginosa; Staphylococcus; Thiouracil; Thymidine; Uracil

1972
Conformation of nucleosides. Dipole moments of pyrimidine nucleosides.
    Biochimica et biophysica acta, 1974, Aug-29, Volume: 361, Issue:2

    Topics: Acetals; Arabinose; Bromouracil; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Cytidine; Deoxyribonucleosides; Ethers, Cyclic; Furans; Glycosides; Light; Mathematics; Molecular Conformation; Optics and Photonics; Pyrimidine Nucleosides; Ribonucleosides; Thiouracil; Thiouridine; Thymine; Uracil; Uridine

1974
Photoreaction of 4-thiouracil with cytosine. Relation to photoreactions in Escherichia coli transfer ribonucleic acids.
    Biochemistry, 1972, Jan-04, Volume: 11, Issue:1

    Topics: Borohydrides; Chemical Phenomena; Chemistry; Cytosine; Escherichia coli; Fluorometry; Models, Chemical; Models, Structural; Oxidation-Reduction; Photochemistry; Pyrimidinones; Radiation Effects; RNA, Transfer; Spectrophotometry; Thiouracil; Ultraviolet Rays; Uracil

1972
Biosynthesis of willardiine and isowillardiine in germinating pea seeds and seedlings.
    The Biochemical journal, 1972, Volume: 129, Issue:4

    Topics: Alanine; Carbon Isotopes; Chromatography, Ion Exchange; Light; Orotic Acid; Pyrimidinones; Seeds; Structure-Activity Relationship; Thiouracil; Uracil

1972
Influence of metal ions on systems of dimethylsulfoxide-uracil-derivatives: NMR investigations.
    Biophysik, 1973, Volume: 10, Issue:3

    Topics: Barbiturates; Bromouracil; Cobalt; Copper; Deuterium; Dimethyl Sulfoxide; Fluorouracil; Ions; Iron; Ligands; Magnetic Resonance Spectroscopy; Metals; Nickel; Silver; Thiouracil; Uracil; Zinc

1973
Toxicity of 2-thiouracil unrelated to thyroid hormone.
    American journal of veterinary research, 1968, Volume: 29, Issue:3

    Topics: Aspartic Acid; Cytosine Nucleotides; Escherichia coli; Nucleic Acids; Thiouracil; Thyroid Hormones; Uracil

1968
Effect of uracil and 2-thiouracil on leucocyte production in the rat.
    Acta haematologica, 1970, Volume: 43, Issue:6

    Topics: Animals; Hematopoiesis; Leukocyte Count; Leukocytes; Lymphocytes; Monocytes; Rats; Thiouracil; Uracil

1970
Enhancement of cowpea chlorotic mottle virus biosynthesis and in vivo infectivity by 2-thiouracil.
    Virology, 1972, Volume: 47, Issue:1

    Topics: Centrifugation, Density Gradient; Cytoplasm; Nicotiana; Nucleoproteins; Phosphorus Isotopes; Plant Diseases; Plant Extracts; Plant Viruses; Plants, Edible; Plants, Toxic; RNA, Viral; Thiouracil; Tobacco Mosaic Virus; Uracil; Viral Proteins; Virus Replication

1972
Pyrimidine nucleosides. IV. Reactions of 3-(beta-D-ribofuranosyl)-uracils.
    Journal of the Chemical Society. Perkin transactions 1, 1970, Volume: 10

    Topics: Bromine; Nucleosides; Ribose; Spectrum Analysis; Thiouracil; Uracil

1970
Nucleosides. 48. Synthesis of 1-(5-deoxy-beta-D-arabinosyl)cytosine and related compounds.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:1

    Topics: Animals; Burkitt Lymphoma; Carbonates; Cytarabine; Humans; Leukemia L1210; Methods; Mice; Nucleosides; Sulfur; Thiouracil; Uracil

1968
Effects of 2-tiouracil and related compounds on pyrimidine metabolism.
    Archives of biochemistry and biophysics, 1968, Sep-10, Volume: 126, Issue:3

    Topics: Animals; Carbon Isotopes; Kinetics; Liver; Male; Nucleotides; Orotic Acid; Pyrimidines; Rats; RNA; Thiouracil; Thiourea; Transferases; Uracil; Uridine

1968
[On the fungicide activity of nucleic acid antagonists (supposed 6-azauracil and 2-thiouracil precursors). (Preliminary report)].
    Acta pharmaceutica Hungarica, 1968, Volume: 38, Issue:2

    Topics: Thiazines; Thiouracil; Uracil

1968
Viruses grown in the presence of base analogs: specific alteration of susceptibility to inactivation by radiations, mutagens, and protodyes.
    Virology, 1966, Volume: 28, Issue:4

    Topics: Arboviruses; Coloring Agents; Fluorouracil; Guanine; Hydroxylamines; In Vitro Techniques; Light; Methylene Blue; Newcastle disease virus; Nitrites; Nucleic Acids; Nucleosides; Photosensitivity Disorders; Purines; Sulfates; Thiouracil; Ultraviolet Rays; Uracil; Uridine; Virus Cultivation; Xanthine Oxidase

1966
[On the role of nucleic acids in the process of chlorophyll biosynthesis].
    Doklady Akademii nauk SSSR, 1966, Feb-21, Volume: 166, Issue:6

    Topics: Azaguanine; Bromodeoxyuridine; Chlorophyll; Dactinomycin; DNA; RNA; Thiouracil; Uracil

1966
[On the experimental study of stomach ulcer in rats].
    Voprosy onkologii, 1966, Volume: 12, Issue:8

    Topics: Animals; Cytosine; Male; Pyrimidines; Rats; Stomach Neoplasms; Stomach Ulcer; Thiouracil; Thymine; Uracil

1966
Some properties of three related viruses: Andean potato latent, dulcamara mottle, and Ononis yellow mosaic.
    Journal of general microbiology, 1966, Volume: 44, Issue:2

    Topics: Animals; Coleoptera; Insect Vectors; Nucleotides; Plant Viruses; Rabbits; Thiouracil; Triazines; Uracil

1966
Chlorophyll formation in Euglena gracilis var. bacillaris: interference by analogues of purines, pyrimidines and amino acids.
    Journal of general microbiology, 1967, Volume: 48, Issue:2

    Topics: Azaguanine; Chlorophyll; Citric Acid Cycle; Ethionine; Euglena; Fluorouracil; Mercaptopurine; Methionine; Purines; Thiouracil; Uracil

1967
A direct synthesis of 1-beta-D-arabinofuranosyl-5-fluorocytosine.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Arabinose; Cytosine; Fluorine; Fluorouracil; Nucleosides; Pyrimidines; Thiouracil; Uracil

1967
Chemical modification of cytosine residues of U6 snRNA with hydrogen sulfide (nucleosides and nucleotides. Part 49 [1]).
    Nucleic acids research, 1983, Sep-10, Volume: 11, Issue:17

    Topics: Animals; Base Sequence; Cells, Cultured; Chemical Phenomena; Chemistry; Hydrogen Sulfide; Kidney; Mice; Mice, Inbred C3H; Nucleic Acid Conformation; Ribonucleases; RNA; RNA, Small Nuclear; Thiouracil; Uracil

1983
Mode of action of the antiphytoviral compound 2,4-dioxohexahydro-1,3,5-triazine (5-azadihydrouracil).
    Intervirology, 1984, Volume: 21, Issue:3

    Topics: Antiviral Agents; Cycloheximide; Drug Interactions; Nicotiana; Plant Diseases; Plant Viruses; Plants, Toxic; Temperature; Thiouracil; Triazines; Uracil; Virus Replication

1984
Horseradish peroxidase inhibition by thiouracils.
    FEBS letters, 1995, Oct-30, Volume: 374, Issue:2

    Topics: Antithyroid Agents; Horseradish Peroxidase; Protein Binding; Spectrophotometry, Ultraviolet; Thiouracil; Uracil

1995
Structure-activity relationship of nucleobase ligands of uridine phosphorylase from Toxoplasma gondii.
    Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10

    Topics: Animals; Binding Sites; Drug Evaluation, Preclinical; Structure-Activity Relationship; Thiouracil; Toxoplasma; Uracil; Uridine Phosphorylase

1993
Anti-HIV active naphthyl analogues of HEPT and DABO.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1997, Volume: 51, Issue:3 Suppl

    Topics: Anti-HIV Agents; Cell Line; Humans; Magnetic Resonance Spectroscopy; Thiouracil; Uracil

1997
Design, synthesis, and characterization of the antitumor activity of novel ceramide analogues.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Division; Ceramides; Cytochrome c Group; Drug Screening Assays, Antitumor; Enzyme Activation; Female; Humans; Immunoblotting; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Structure-Activity Relationship; Thiouracil; Transplantation, Heterologous; Tumor Cells, Cultured; Uracil

2001
Quantum chemical predictions of the vibrational spectra of polyatomic molecules. The uracil molecule and two derivatives.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2002, Volume: 58, Issue:3

    Topics: Benzene; Bromouracil; Models, Chemical; Reproducibility of Results; Silanes; Software; Spectrophotometry; Spectrophotometry, Infrared; Thiouracil; Toluene; Uracil

2002
[Studies on auxin effect. II. Effect of thiouracil on plant growth and specific antagonism between thiouracil and uracil].
    Endokrinologie, 1953, Volume: 30, Issue:3-4

    Topics: Indoleacetic Acids; Plant Development; Plant Physiological Phenomena; Thiouracil; Uracil

1953
Central depressant properties of uracil and related oxypyrimidines.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1955, Volume: 44, Issue:1

    Topics: Central Nervous System; Central Nervous System Agents; Humans; Hypnotics and Sedatives; Pyrimidines; Thiouracil; Thymine; Uracil

1955
Inhibition studies with pyrimidines on Streptococcus faecalis R.
    The Journal of biological chemistry, 1955, Volume: 212, Issue:1

    Topics: Enterococcus faecalis; Pyrimidines; Streptococcus; Thiouracil; Uracil

1955
The relationship of uracil, orotic acid and thiouracil in mammalian thyroid tissue.
    Endocrinology, 1961, Volume: 68

    Topics: Animals; Orotic Acid; Thiouracil; Thyroid Gland; Uracil

1961
Further studies on experimental atherosclerosis and dietary pyrimidines: orotic acid, thiouracil, and uracil in male and female rats.
    Circulation research, 1960, Volume: 8

    Topics: Animals; Atherosclerosis; Diet; Female; Male; Orotic Acid; Pyrimidines; Rats; Thiouracil; Uracil

1960
[The utilization of thiouracil by pyrimidine-less mutants of Escherichia coli].
    Archives internationales de physiologie et de biochimie, 1963, Volume: 71

    Topics: Escherichia coli; Pyrimidines; Thiouracil; Uracil

1963
Structural specificity of the pyrimidine transport process of the small intestine.
    Biochemical pharmacology, 1962, Volume: 11

    Topics: Barbiturates; Cytosine; Intestine, Small; Intestines; Pyrimidines; Thiouracil; Thymine; Uracil

1962
CONTROL OF URACIL SYNTHESIS BY ARGININE IN ESCHERICHIA COLI.
    Journal of bacteriology, 1964, Volume: 87

    Topics: Arginine; Carboxyl and Carbamoyl Transferases; Escherichia coli; Israel; Metabolism; Ornithine; Ornithine Carbamoyltransferase; Pharmacology; Research; Thiouracil; Transferases; Uracil

1964
THIOURACIL-PYRIMIDINE RELATIONSHIPS IN THYROID AND OTHER TISSUES.
    Endocrinology, 1965, Volume: 76

    Topics: Animals; Carbon Dioxide; Carbon Isotopes; Cattle; Liver; Metabolism; Organ Size; Orotic Acid; Pharmacology; Pyrimidines; Rats; Research; RNA; Thiouracil; Thymine; Thymus Gland; Thyroid Gland; Uracil; Uracil Nucleotides

1965
NUCLEIC ACID SYNTHESIS IN NORMAL AND GOITROUS RAT THYROID.
    Endocrinology, 1965, Volume: 76

    Topics: Antithyroid Agents; Carbon Isotopes; Chromatography; Cytosine Nucleotides; DNA; Glucosyltransferases; Goiter; Metabolism; Orotic Acid; Pharmacology; Phosphotransferases; Rats; Research; RNA; Spectrophotometry; Thiouracil; Thyroid Gland; Uracil; Uracil Nucleotides

1965
PROTECTIVE ACTION BY THIOURACIL AGAINST THE ACUTE TOXICITY IN MICE OF O-ETHYL O-(4-NITROPHENYL) PHENYLPHOSPHONOTHIOATE (EPN).
    Toxicology and applied pharmacology, 1965, Volume: 7

    Topics: Antidotes; Antimetabolites; Fatty Acids; Insecticides; Mice; Nitrophenols; Parathion; Pharmacology; Proadifen; Research; Thiouracil; Toxicology; Uracil

1965
Gas-phase reactivity of uracil, 2-thiouracil, 4-thiouracil, and 2,4-dithiouracil towards the Cu+ cation: a DFT study.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2003, Sep-15, Volume: 4, Issue:9

    Topics: Cations; Copper; Electron Transport; Gases; Hydrogen Bonding; Molecular Conformation; Organometallic Compounds; Oxygen; Stereoisomerism; Structure-Activity Relationship; Sulfur; Thermodynamics; Thiouracil; Uracil

2003
Synthesis and antiviral activity of 1,3-disubstituted uracils against HIV-1 and HCMV.
    Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:5

    Topics: Antiviral Agents; Cytomegalovirus; HIV-1; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiouracil; Uracil

2003
[Inhibition of bacterial growth by thiouracil derivatives and antagonistic effect of uracil].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1951, Volume: 145, Issue:3-4

    Topics: Lacticaseibacillus casei; Thiouracil; Uracil

1951
Competitive action of 2-thiouracil and uracil in AAF-induced cancer of the liver.
    Science (New York, N.Y.), 1951, Sep-07, Volume: 114, Issue:2958

    Topics: Carcinogenesis; Humans; Liver Neoplasms; Neoplasms; Thiouracil; Uracil

1951
[Effect of uracil derivatives on the thymus].
    Klinische Wochenschrift, 1951, Sep-01, Volume: 29, Issue:33-34

    Topics: Humans; Thiouracil; Thymus Gland; Uracil

1951
Association of Cu2+ with uracil and its thio derivatives: a theoretical study.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2004, Dec-10, Volume: 5, Issue:12

    Topics: Cations; Copper; Free Radicals; Models, Chemical; Molecular Structure; Thermodynamics; Thiouracil; Uracil

2004
5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:6

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biological Availability; Body Weight; Female; Fluorouracil; Mice; Mice, Inbred Strains; Thiouracil; Uracil; Uridine; Uridine Phosphorylase

2005
Condensation of nucleobases at mercury/aqueous solution interface--a structural perspective using hydrogen bonding considerations.
    Journal of colloid and interface science, 2002, Jun-01, Volume: 250, Issue:1

    Topics: Adenine; Adenosine; Adsorption; Cytosine; Electrodes; Electrolytes; Guanine; Hydrogen Bonding; Mercury; Potassium; Purines; Pyrimidines; Sodium; Solutions; Thermodynamics; Thiouracil; Thymine; Uracil; Water

2002
Gas-phase deprotonation of uracil-Cu2+ and thiouracil-Cu2+ complexes.
    The journal of physical chemistry. A, 2006, Feb-09, Volume: 110, Issue:5

    Topics: Binding Sites; Copper; Free Radicals; Gases; Models, Molecular; Molecular Structure; Organometallic Compounds; Protons; Thiouracil; Uracil

2006
Spectral properties of some metal complexes derived from uracil-thiouracil and citrazinic acid compounds.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 67, Issue:3-4

    Topics: Acids; Cobalt; Copper; Electron Probe Microanalysis; Electron Spin Resonance Spectroscopy; Iron; Ligands; Magnetics; Metals, Heavy; Molecular Structure; Nickel; Organic Chemicals; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Mossbauer; Thiouracil; Uracil

2007
Antagonistic Action of Uracil, Thiouracil, and Thiourea on Reticulocyte Ripening.
    Science (New York, N.Y.), 1952, Mar-14, Volume: 115, Issue:2985

    Topics: Erythrocytes; Reticulocytes; Thiouracil; Thiourea; Uracil

1952
Effect of thiouracil and uracil on the germination of cress seeds.
    Nature, 1949, Jul-09, Volume: 164, Issue:4158

    Topics: Brassicaceae; Germination; Seeds; Thiouracil; Thiourea; Uracil; Vegetables

1949
The mechanism of double proton transfer in dimers of uracil and 2-thiouracil--the reaction force perspective.
    Journal of computational chemistry, 2009, Volume: 30, Issue:3

    Topics: Computer Simulation; Dimerization; Hydrogen Bonding; Models, Chemical; Protons; Quantum Theory; Thiouracil; Uracil; Vibration

2009
Regio- and chemoselective magnesiation of protected uracils and thiouracils using TMPMgCl x LiCl and TMP(2)Mg x 2 LiCl.
    Organic & biomolecular chemistry, 2008, Sep-21, Volume: 6, Issue:18

    Topics: Magnesium; Molecular Structure; Organometallic Compounds; Stereoisomerism; Sulfhydryl Compounds; Thiouracil; Uracil

2008
DFT study of molecular geometries and vibrational characteristics of uracil and its thio-derivatives and their radical cations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2010, Volume: 75, Issue:1

    Topics: Cations; Computer Simulation; Models, Molecular; Molecular Structure; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Thiouracil; Uracil; Vibration

2010
Thiothymine (2-thio-5-methyl-uracil).
    Nature, 1947, May-17, Volume: 159, Issue:4046

    Topics: Thiouracil; Thymine; Uracil

1947
Synthesis and anti-hepatitis B activity of new substituted uracil and thiouracil glycosides.
    Archives of pharmacal research, 2010, Volume: 33, Issue:6

    Topics: Algorithms; Antiviral Agents; Drug Design; Glycosides; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiouracil; Uracil; Viral Plaque Assay

2010
Effect of Sr2+ association on the tautomerization processes of uracil and its dithio- and diseleno-derivatives.
    Organic & biomolecular chemistry, 2011, Jan-21, Volume: 9, Issue:2

    Topics: Catalysis; Cations, Divalent; Molecular Structure; Selenium Compounds; Stereoisomerism; Strontium; Thiouracil; Uracil

2011
Polarization in the structures of uracil and thiouracils: Implication for binding with orotidine 5'-monophosphate decarboxylase.
    Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21

    Topics: Orotidine-5'-Phosphate Decarboxylase; Protein Binding; Thiouracil; Uracil

2011
Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs.
    The Journal of biological chemistry, 2013, Oct-11, Volume: 288, Issue:41

    Topics: Cations, Divalent; Chromatography, Gel; Enzyme Stability; Feedback, Physiological; Fluorouracil; Hydrogen-Ion Concentration; Kinetics; Leishmania donovani; Mutation; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Protein Multimerization; Protozoan Proteins; Pyrimidines; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Temperature; Thiouracil; Uracil

2013
Cocrystals of 6-methyl-2-thiouracil: presence of the acceptor-donor-acceptor/donor-acceptor-donor synthon.
    Acta crystallographica. Section C, Structural chemistry, 2015, Volume: 71, Issue:Pt 3

    Topics: Antithyroid Agents; Crystallography, X-Ray; Cystine; Hydrogen Bonding; Molecular Structure; Pyrimidines; Thiouracil; Uracil

2015
Functionalisation and immobilisation of an Au(110) surface via uracil and 2-thiouracil anchored layer.
    Physical chemistry chemical physics : PCCP, 2015, Jun-21, Volume: 17, Issue:23

    Topics: Adsorption; Gold; Immobilized Nucleic Acids; Surface Properties; Thermodynamics; Thiouracil; Uracil; X-Ray Absorption Spectroscopy

2015
Eight new crystal structures of 5-(hydroxymethyl)uracil, 5-carboxyuracil and 5-carboxy-2-thiouracil: insights into the hydrogen-bonded networks and the predominant conformations of the C5-bound residues.
    Acta crystallographica. Section C, Structural chemistry, 2016, 05-01, Volume: 72, Issue:Pt 5

    Topics: Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Pentoxyl; Thiouracil; Uracil

2016
A gene encoding a DUF523 domain protein is involved in the conversion of 2-thiouracil into uracil.
    Environmental microbiology reports, 2018, Volume: 10, Issue:1

    Topics: Amino Acid Substitution; Escherichia coli; Escherichia coli Proteins; Gene Library; Genes, Bacterial; Holoenzymes; Iron; Models, Chemical; RNA; Soil Microbiology; Sulfur; Thiouracil; Uracil

2018
Selective 4-Thiouracil Labeling of RNA Transcripts within Latently Infected Cells after Infection with Human Cytomegalovirus Expressing Functional Uracil Phosphoribosyltransferase.
    Journal of virology, 2018, 11-01, Volume: 92, Issue:21

    Topics: Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Humans; Pentosyltransferases; RNA, Viral; Staining and Labeling; Thiouracil; Uracil; Virus Latency

2018
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents.
    Molecules (Basel, Switzerland), 2018, Nov-08, Volume: 23, Issue:11

    Topics: Animals; Antithyroid Agents; Binding Sites; Disease Models, Animal; Hydrophobic and Hydrophilic Interactions; Hyperthyroidism; Lactoperoxidase; Models, Molecular; Rats; Structure-Activity Relationship; Thiouracil; Triiodothyronine; Uracil

2018
Different Oxidation Pathways of 2-Selenouracil and 2-Thiouracil, Natural Components of Transfer RNA.
    International journal of molecular sciences, 2020, Aug-19, Volume: 21, Issue:17

    Topics: Hydrogen Peroxide; Oxidation-Reduction; Thiouracil; Uracil

2020
Electron attachment dynamics following UV excitation of iodide-2-thiouracil complexes.
    The Journal of chemical physics, 2022, Jun-28, Volume: 156, Issue:24

    Topics: Electrons; Iodides; Photoelectron Spectroscopy; Thiouracil; Uracil

2022
Design and synthesis of uracil/thiouracil based quinoline scaffolds as topoisomerases I/II inhibitors for chemotherapy: A new hybrid navigator with DFT calculation.
    Bioorganic chemistry, 2023, Volume: 136

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Density Functional Theory; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Molecular Docking Simulation; Molecular Structure; Quinolines; Structure-Activity Relationship; Thiouracil; Topoisomerase II Inhibitors; Uracil

2023
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