uracil and oxonic acid

uracil has been researched along with oxonic acid in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.33)	18.7374
1990's	7 (8.14)	18.2507
2000's	45 (52.33)	29.6817
2010's	31 (36.05)	24.3611
2020's	1 (1.16)	2.80

Authors

Authors	Studies
Hropot, M; Lang, HJ; Muschaweck, R; Sörgel, F; von Kerékjártó, B	1
Ketley, K; O'Sullivan, WJ	1
Kouchi, Y; Maeda, Y; Morinaga, H; Ohuchida, A	1
Ajani, JA	1
Brito, R; Hoff, PM; Medgyesy, D; Pazdur, R; Royce, M	2
Taguchi, T	1
Brito, RA; Hoff, PM; Medgyesy, D; Pazdur, R; Ravandi-Kashani, F; Royce, ME; Zukowski, TH	1
Ikeda, Y; Mizuno, H; Nishimura, G; Satake, K; Taguchi, T; Tsukuda, M; Yanoma, S	1
Ikeda, K; Kawaguchi, Y; Masuda, H; Matsushima, E; Nagayama, S; Yoshisue, K	1
Peeters, M; Van Cutsem, E	1
Shirasaka, T; Taguchi, T; Tsuji, A; Yamamitsu, S	1
Hoff, PM	2
Diasio, RB	1
Wada, H	1
Kubota, T	1
Fumoleau, P; Gall, H; Giaccone, G; Holwerda, U; Noordhuis, P; Peters, GJ; Schornagel, JH; Smid, K; Swart, MS; Turner, SL; Van Gennip, AH; Van Groeningen, CJ; Van Kuilenburg, AB; Voorn, D; Wanders, J	1
Goda, F; Hagiike, M; Ishimura, K; Izuishi, K; Karasawa, Y; Maeta, H; Okano, K; Usuki, H; Yachida, S	1
Abe, K; Fujiwara, H; Gotoh, M; Hoshino, Y; Irinoda, T; Kanzaki, N; Kogure, M; Nakaya, T; Nemoto, T; Ohtani, S; Oyama, K; Saito, K; Takagane, A; Terashima, M; Yonezawa, H	1
Ikeda, H; Inokuchi, T; Irie, A; Mizoguchi, Y; Shibahara, K; Takebe, Y; Yamada, K	1
Goto, M; Hamaguchi, T; Matsumura, Y; Muro, K; Nagayama, S; Shimada, Y; Shirao, K; Yamada, Y	1
Hosokawa, A	1
Doi, T; Ohtsu, A	1
Hachino, Y; Kawato, N; Makihara, K; Mishima, H; Morimoto, S; Shono, Y; Tabuse, K; Tsuji, T; Tsujinaka, T	1
Damdinsuren, B; Dono, K; Kondo, M; Marubashi, S; Miyamoto, A; Monden, M; Nagano, H; Nakamori, S; Nakamura, M; Ota, H; Sakon, M; Umeshita, K; Wada, H; Yamamoto, T; Yang, Y	1
Fujioka, A; Fukushima, M; Ikeda, K; Kitazato, K; Nakagawa, F; Ohshimo, H; Okabe, H; Takechi, T	1
Kobayashi, M; Kodera, Y; Macdonald, JS; Miyashita, Y; Morita, S; Sakamoto, J; Tsuburaya, A	1
Ikeda, M; Morizane, C; Okusaka, T; Ueno, H	1
Hasuo, T; Ikeshima, S; Ishihara, K; Iwatsuki, M; Kuramoto, M	1
Kagaya, T; Kaneko, S; Kato, Y; Sunagozaka, H; Yamashita, T	1
Arai, K; Hashimoto, T; Hiruma, K; Iwasaki, Y; Matsumoto, H; Saze, Z; Takahashi, K; Yamaguchi, T; Yamashita, Y; Yasutome, M	1
Fukushima, M	1
Furuhata, T; Hirata, K; Horikoshi, N; Ishizuka, H; Nakano, Y; Okazaki, M; Sasaki, K; Shirasaka, T; Sohma, K; Taguchi, T; Tominaga, K; Uno, S; Yamada, Y; Yamaguchi, K; Yamamitsu, S	1
Yamada, Y	1
Baba, H; Egashira, A; Ikeda, K; Kakeji, Y; Koga, T; Maehara, Y; Morita, M; Nishida, K; Oki, E; Tokunaga, E; Yoshida, R	1
Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Toth, G; Tsukuda, M; Yoshida, T	1
Aikou, T; Kitazono, M; Kubo, F; Maemura, K; Noma, H; Sakoda, M; Shinchi, H; Takao, S; Ueno, S	1
Akagawa, T; Fujioka, S; Hara, T; Hiramatsu, K; Hirata, A; Ito, T; Kato, K; Kutsuna, Y; Machiki, Y; Matsuba, H; Miyata, T	1
López-Brea, MF; Rivera, F; Vega-Villegas, ME	1
Aoki, T; Mino, A; Murahashi, K; Nishino, K; Sowa, M; Tachimori, A; Takagaki, K	1
Komatsu, Y	1
Hori, S; Inoue, S; Ohtani, H; Sawada, Y; Tsujimoto, M	1
Cho, H; Hasegawa, S; Kobayashi, O; Osaragi, T; Sairenji, M; Tsuburaya, A; Yoshida, T; Yoshikawa, T	1
Akamaru, Y; Beppu, N; Ito, A; Kasugai, T; Momiyama, T; Nakamura, Y; Ohno, K; Sugimoto, Y; Tamaoka, N; Watanabe, Y; Yamasaki, Y; Yumiba, T	1
Fujimoto, T; Kuhara, K; Matsumoto, A; Ogawa, K; Osawa, G; Otani, T; Shimakawa, T; Umehara, A; Yokomizo, H; Yoshimatsu, K	1
Akiyama, I; Fujita, Y; Hasegawa, K; Morimoto, S; Shono, Y; Tabuse, K; Tsuji, T	1
Bang, YJ; Heo, DS; Im, SA; Kim, DW; Kim, MJ; Kim, TY; Lee, SH; Oh, DY	1
Hanauske, A; Hilger, RA; Krauss, J; Kredtke, S; Makris, L; Mende, B; Scheulen, ME; Scigalla, P; Strumberg, D; Thyssen, D; Urrea, PD	1
Fukunaga, M; Furukawa, H; Ishida, H; Kato, T; Miyake, Y; Takemoto, H; Watanabe, Y	1
Hamaguchi, T; Hirashima, Y; Kato, K; Matsubara, J; Okita, NT; Shimada, Y; Shimoda, T; Shirao, K; Takahari, D; Taniguchi, H; Yamada, Y	1
Kira, M; Takizawa, H; Tangoku, A; Toba, H; Yamai, H; Yoshida, T	1
Chiba, A; Fujii, T; Habiro, A; Kohgo, Y; Koizumi, K; Mizukami, Y; Nakamura, K; Nakano, Y; Nishikawa, T; Okumura, T; Sasajima, J; Sugiyama, Y; Tanno, S	1
Asai, S; Ishii, Y; Suzuki, S; Takahashi, Y; Takayama, T	1
Fukushima, M; Tanaka, F; Wada, H	1
Nakayama, T; Noguchi, S	1
Arita, M; Kuga, Y; Miwata, T; Moriya, T; Murakami, E; Nishida, T; Numata, Y; Ohya, T; Okanobu, H; Tanaka, T; Yoshimi, S	1
Saito, T; Sasaki, H; Tokunaga, Y	1
Hirai, T; Ito, Y; Kato, T; Kodera, Y; Nakanishi, H; Nakao, A	1
Kawai, K; Kitayama, J; Nagawa, H; Sunami, E; Yasuda, K	1
Abe, M; Kiniwa, M; Matsuo, K; Nakagawa, F; Noguchi, S; Nukatsuka, M; Saito, H; Shibata, J; Uchida, J	1
Baba, H; Beppu, T; Okabe, K; Sano, O; Sugiyama, S; Wada, A; Yamanaka, T	1
Akitake, H; Ebisui, C; Fujimoto, T; Hama, N; Kashiwazaki, M; Konishi, M; Maekawa, T; Ohkubo, K; Ohtsuka, M; Taniguchi, M; Tsujie, M; Yoshioka, S	1
Fujita, S; Ikeda, N; Kanamura, T; Kojima, Y; Nakagawa, K; Ueno, M	1
Amano, R; Hirakawa, K; Inoue, T; Ishikawa, T; Kubo, N; Lee, T; Maeda, K; Muguruma, K; Nagahara, H; Nakata, B; Noda, E; Ohira, M; Onoda, N; Sawada, T; Takashima, T; Tanaka, H; Yamada, N; Yashiro, M	1
Amano, K; Aratake, K; Hashimoto, T; Hirosawa, T; Itabashi, M; Kameoka, S; Narita, T; Ogawa, S; Seshimo, A	1
Kume, H	1
Edagawa, A; Ikeda, Y; Itoh, S; Kakeji, Y; Kawanaka, H; Korenaga, D; Maehara, Y; Oki, E; Okuyama, T; Takenaka, K; Tateishi, M; Tsujitani, S	1
Boku, N; Endo, T; Ikejiri, K; Kameoka, S; Kinugasa, Y; Kotake, K; Matsubara, Y; Mochizuki, H; Mochizuki, I; Nakamoto, Y; Shinozaki, H; Sugihara, K; Takagane, A; Takahashi, K; Takahashi, Y; Takii, Y; Takiuchi, H; Tomita, N; Watanabe, M; Watanabe, T	1
Chu, Y; Ding, L; Liu, HY; Yu, Y; Zhu, H	1
Enomoto, K; Ito, M; Kurumatani, N; Matsumoto, S; Migita, K; Nakajima, Y; Saeki, K; Takayama, T; Tanaka, T; Wakatsuki, K	1
Benson, AB	1
Kato, T; Kobayashi, A; Nakamura, Y; Nakayama, H; Okamura, R; Wada, S; Yoh, T	1
Furuse, H; Ishii, Y; Kai, F; Nagata, M; Otsuka, A; Ozono, S; Sugiyama, T; Suzuki, T; Takayama, T; Yajima, T	1
Boku, N; Endo, T; Ikejiri, K; Ishiguro, M; Kameoka, S; Kinugasa, Y; Kotake, K; Mochizuki, H; Mochizuki, I; Nakamoto, Y; Nakatani, E; Shinozaki, H; Sugihara, K; Takagane, A; Takahashi, K; Takii, Y; Tomita, N; Watanabe, M; Watanabe, T; Yoshida, M	1
Buyse, M; Fukushima, R; Hara, A; Imamura, H; Kobayashi, M; Kojima, H; Miyashita, Y; Morita, S; Nishikawa, K; Nozaki, I; Oba, K; Sakamoto, J; Takahashi, M; Takahashi, N; Takiguchi, N; Tanabe, K; Tatsumoto, N; Tsuburaya, A; Yoshida, K; Yoshino, S	1
Ishiguro, M; Sugihara, K; Yoshida, M	1
Abali, H; Calıkusu, Z; Seyrek, E; Yavuz, S	1
Hishida, T; Kunitoh, H; Ohashi, Y; Sakurai, H; Shukuya, T; Takamochi, K; Tsuboi, M; Yoh, K	1
Hwang, SH; Kim, SG	1
Baba, H; Emi, Y; Hamada, C; Ikejiri, K; Kakeji, Y; Kotake, M; Maeda, K; Maehara, Y; Matsuda, C; Matsuda, H; Munemoto, Y; Murata, A; Oki, E; Saji, S; Sasaki, K; Suenaga, T; Yoshida, K	1
Kamijo, A; Nagase, H; Okada, K; Sadahiro, S; Saito, G; Suzuki, T; Tanaka, A	1
Aiba, K; Baba, H; Boku, N; Ishiguro, M; Itabashi, M; Kotake, K; Kunieda, K; Kusumoto, T; Maeda, A; Mochizuki, I; Morita, S; Okabe, M; Ota, M; Sakamoto, Y; Sugihara, K; Sunami, E; Takahashi, K; Tomita, N; Yamauchi, J; Yoshida, K	1
Beppu, T; Fujii, M; Hanamure, Y; Hasegawa, Y; Higaki, Y; Iwae, S; Kawabata, K; Kohno, N; Kubota, A; Nagahara, K; Nakatani, E; Nakatani, H; Taguchi, T; Takemura, H; Terada, T; Teramukai, S; Tomita, K; Tsukahara, K; Yoshino, K	1
Milano, G	1
Chen, CN; Lai, IR; Yeh, CC; Yen, HH	1

Reviews

22 review(s) available for uracil and oxonic acid

Article	Year
Chemotherapy for gastric carcinoma: new and old options. Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:10 Suppl 7 Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Deoxycytidine; Docetaxel; Drug Combinations; Enzyme Inhibitors; Etoposide; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Oxonic Acid; Paclitaxel; Pyridines; Randomized Controlled Trials as Topic; Stomach Neoplasms; Taxoids; Tegafur; Uracil	1998
The oral fluorouracil prodrugs. Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:10 Suppl 7 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	1998
[Gastrointestinal cancer and oral anticancer agents]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Drug Combinations; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	1999
Fluoropyrimidines: a critical evaluation. Oncology, 1999, Volume: 57 Suppl 1 Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Pyridines; Tegafur; Uracil	1999
Oral fluoropoyrimidines. Seminars in oncology, 1999, Volume: 26, Issue:6 Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	1999
Oral fluoropyrimidines in colorectal cancer. Seminars in oncology, 2000, Volume: 27, Issue:5 Suppl 10 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Pyridines; Tegafur; Uracil	2000
Conceptual changes in cancer chemotherapy: from an oral fluoropyrimidine prodrug, UFT, to a novel oral fluoropyrimidine prodrug, S-1, and low-dose FP therapy in Japan. Investigational new drugs, 2000, Volume: 18, Issue:4 Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Drug Synergism; Drug Therapy; Fluorouracil; Humans; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	2000
The tegafur-based dihydropyrimidine dehydrogenase inhibitory fluoropyrimidines, UFT/leucovorin (ORZEL) and S-1: a review of their clinical development and therapeutic potential. Investigational new drugs, 2000, Volume: 18, Issue:4 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Humans; Leucovorin; Neoplasms; Oxidoreductases; Oxonic Acid; Pyridines; Radiation-Sensitizing Agents; Tegafur; Uracil	2000
Oral DPD-inhibitory fluoropyrimidine drugs. Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:10 Suppl 9 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil	2000
[5-fluorouracil and dihydropyrimidine dehydrogenase]. Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:4 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil	2001
Practical considerations in the use of oral fluoropyrimidines. Seminars in oncology, 2003, Volume: 30, Issue:3 Suppl 6 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	2003
[Intravenous continuous infusion of fluorouracil for treatment of metastatic colorectal cancer]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Oxonic Acid; Prognosis; Pyridines; Tegafur; Thymidylate Synthase; Uracil	2003
[Present status of chemotherapy for colorectal cancer in countries outside of Japan]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7 Topics: Administration, Oral; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Humans; Irinotecan; Japan; Leucovorin; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prognosis; Pyridines; Tegafur; United States; Uracil	2003
[5 -fluoropyrimidines for treatment of biliary tract cancers]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 1 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Pyridines; Pyrimidines; Tegafur; Uracil	2006
[Pharmacokinetics of S-1]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1 Topics: Administration, Oral; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Humans; Kidney; Male; Middle Aged; Neoplasms; Oxonic Acid; Rats; Tegafur; Uracil	2006
[Clinical efficacy of administration with S-1 alone for head and neck carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials, Phase II as Topic; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Oxonic Acid; Tegafur; Uracil	2006
Chemotherapy of advanced gastric cancer. Cancer treatment reviews, 2007, Volume: 33, Issue:4 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Docetaxel; Drug Combinations; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Stomach Neoplasms; Taxoids; Tegafur; Uracil	2007
[Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Europe; Evidence-Based Medicine; Fluorouracil; Humans; Irinotecan; Japan; Leucovorin; Neoplasm Staging; Oxonic Acid; Practice Guidelines as Topic; Rectal Neoplasms; Tegafur; United States; Uracil	2007
UFT and S-1 for treatment of primary lung cancer. General thoracic and cardiovascular surgery, 2010, Volume: 58, Issue:1 Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Evidence-Based Medicine; Humans; Lung Neoplasms; Oxonic Acid; Radiotherapy, Adjuvant; Tegafur; Time Factors; Treatment Outcome; Uracil	2010
Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan. The oncologist, 2010, Volume: 15, Issue:1 Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Japan; Methotrexate; Oxonic Acid; Tegafur; Uracil	2010
[Two cases of the primary small intestine cancer successfully treated with S-1 and UFT/LV therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12 Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Humans; Jejunal Neoplasms; Leucovorin; Male; Middle Aged; Oxonic Acid; Tegafur; Uracil	2010
Applications of oral fluoropyrimidines in colon cancer: their role and new directions. Journal of the National Comprehensive Cancer Network : JNCCN, 2003, Volume: 1 Suppl 3 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Oxaloacetates; Oxonic Acid; Tegafur; Uracil	2003

Trials

12 trial(s) available for uracil and oxonic acid

Article	Year
Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors. Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:1 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Drug Combinations; Female; Fluorouracil; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Oxonic Acid; Pyridines; Tegafur; Tissue Distribution; Uracil	2003
Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2003, Volume: 6 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Japan; Liver Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Middle Aged; Multivariate Analysis; Neoplasm Staging; Oxidoreductases; Oxonic Acid; Peritoneal Neoplasms; Predictive Value of Tests; Pyridines; Retrospective Studies; Statistics as Topic; Stomach Neoplasms; Survival Analysis; Tegafur; Thymidine Phosphorylase; Thymidylate Synthase; Treatment Outcome; Uracil	2003
A randomized phase III trial of post-operative adjuvant oral fluoropyrimidine versus sequential paclitaxel/oral fluoropyrimidine; and UFT versus S1 for T3/T4 gastric carcinoma: the Stomach Cancer Adjuvant Multi-institutional Trial Group (Samit) Trial. Japanese journal of clinical oncology, 2005, Volume: 35, Issue:11 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Endpoint Determination; Humans; Middle Aged; Oxonic Acid; Paclitaxel; Pyridines; Pyrimidines; Stomach Neoplasms; Tegafur; Uracil	2005
[A randomized controlled trial to evaluate the effect of adjuvant oral fluoropyrimidine derivative therapy after curative resection for stage II/III rectal cancer-adjuvant chemotherapy trial of S-1 for rectal cancer (ACTS-RC):]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Endpoint Determination; Female; Humans; Lymph Node Excision; Male; Neoplasm Staging; Oxonic Acid; Proportional Hazards Models; Prospective Studies; Rectal Neoplasms; Survival Rate; Tegafur; Uracil	2006
Development of a pharmacokinetic model to optimize the dosage regimen of TS-1, a combination preparation of tegafur, gimeracil and oteracil potassium. Drug metabolism and pharmacokinetics, 2007, Volume: 22, Issue:3 Topics: Administration, Oral; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Computer Simulation; Drug Combinations; Fluorouracil; Humans; Kidney; Kinetics; Models, Biological; Oxonic Acid; Pyridines; Renal Insufficiency; Tegafur; Time Factors; Uracil	2007
A feasibility study of UFT/LV and irinotecan (TEGAFIRI) in advanced or metastatic colorectal cancer: Osaka Gastrointestinal Cancer Chemotherapy Study Group (OGSG) PROG 0304. Japanese journal of clinical oncology, 2009, Volume: 39, Issue:9 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Combinations; Feasibility Studies; Female; Humans; Immunoenzyme Techniques; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Survival Rate; Tegafur; Uracil	2009
Safety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial. British journal of cancer, 2012, Mar-27, Volume: 106, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Oxonic Acid; Tegafur; Uracil	2012
S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial). Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Tegafur; Uracil; Young Adult	2014
Sequential paclitaxel followed by tegafur and uracil (UFT) or S-1 versus UFT or S-1 monotherapy as adjuvant chemotherapy for T4a/b gastric cancer (SAMIT): a phase 3 factorial randomised controlled trial. The Lancet. Oncology, 2014, Volume: 15, Issue:8 Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Combinations; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Neoplasm Staging; Neutropenia; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Survival Rate; Tegafur; Uracil	2014
A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC). Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Japan; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Rectal Neoplasms; Tegafur; Uracil	2016
Planned Safety Analysis of the ACTS-CC 02 Trial: A Randomized Phase III Trial of S-1 With Oxaliplatin Versus Tegafur and Uracil With Leucovorin as Adjuvant Chemotherapy for High-Risk Stage III Colon Cancer. Clinical colorectal cancer, 2018, Volume: 17, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Oxaliplatin; Oxonic Acid; Tegafur; Uracil	2018
Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study. PloS one, 2018, Volume: 13, Issue:6 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Squamous Cell Carcinoma of Head and Neck; Tegafur; Treatment Outcome; Uracil	2018

Other Studies

52 other study(ies) available for uracil and oxonic acid

Article	Year
Pharmacological effects of 1,3,5-triazines and their excretion characteristics in the rat. Advances in experimental medicine and biology, 1980, Volume: 122A Topics: Animals; Kidney; Kinetics; Male; Oxonic Acid; Purines; Rats; Structure-Activity Relationship; Triazines; Uracil; Urate Oxidase; Uric Acid	1980
Biosynthesis of uridine monophosphate in Plasmodium berghei. Annals of tropical medicine and parasitology, 1980, Volume: 74, Issue:2 Topics: Animals; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxonic Acid; Plasmodium berghei; Potassium; Uracil; Uracil Nucleotides; Uridine Monophosphate	1980
[Immunotoxic effects of a new antineoplastic agent S-1 in mice--comparison with S-1, UFT and 5-FU]. The Journal of toxicological sciences, 1996, Volume: 21 Suppl 3 Topics: Animals; Antibody Formation; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Immune System; Immune Tolerance; Immunologic Tests; Mice; Mice, Inbred BALB C; Organ Size; Oxonic Acid; Pyridines; Spleen; Tegafur; Thymus Gland; Uracil	1996
Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypridine-1 M potassium oxonate (S-1) on head and neck squamous carcinoma cells. Cancer letters, 2000, Oct-16, Volume: 159, Issue:1 Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Oxonic Acid; Pyridines; Survival Rate; Tegafur; Transplantation, Heterologous; Tumor Cells, Cultured; Uracil	2000
Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats. Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10 Topics: Administration, Oral; Allopurinol; Animals; Antimetabolites, Antineoplastic; Area Under Curve; Biotransformation; Carbon Radioisotopes; Chlorpromazine; Drug Combinations; Drugs, Chinese Herbal; Fluorouracil; Glycyrrhiza; Intestine, Small; Male; Microsomes, Liver; Oxonic Acid; Paeonia; Pyridines; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Tegafur; Tissue Distribution; Triazines; Uracil; Xanthine Oxidase	2000
[Oral chemotherapeutic agents: the roles in cancer chemotherapy]. Nihon geka hokan. Archiv fur japanische Chirurgie, 1999, Sep-01, Volume: 68, Issue:2 Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxonic Acid; Pyridines; Tegafur; Uracil	1999
Dihydropyrimidine dehydrogenase (DPD) activity in gastric cancer tissue and effect of DPD inhibitory fluoropyrimidines. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2003, Volume: 6 Suppl 1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NADP); Disease Progression; Drug Combinations; Enzyme Inhibitors; Fluorouracil; Humans; Japan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Oxidoreductases; Oxonic Acid; Peritoneal Neoplasms; Prognosis; Pyridines; Statistics as Topic; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil	2003
[A case report of tongue squamous cell carcinoma showing a complete response to TS-1]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:5 Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Combinations; Female; Humans; Oxonic Acid; Pyridines; Remission Induction; Tegafur; Tongue Neoplasms; Uracil	2003
Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil. British journal of cancer, 2003, Sep-01, Volume: 89, Issue:5 Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; beta-Alanine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil	2003
[Support of TS-1, 5-FU preparation containing potent DPD inhibitor by determination of urinary uracil/serum 5-FU clearance]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:13 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Uracil	2003
[A case of long-term survivor with multiple pulmonary metastases of HCC after hepatic resection]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Combinations; Fluorouracil; Hepatectomy; Humans; Interferon-alpha; Interferon-beta; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pyridines; Tegafur; Time Factors; Uracil	2004
Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts. Oncology reports, 2005, Volume: 14, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Line, Tumor; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Floxuridine; Fluorouracil; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Orotate Phosphoribosyltransferase; Oxonic Acid; Pyridines; Tegafur; Thymidine Phosphorylase; Treatment Outcome; Uracil; Xenograft Model Antitumor Assays	2005
[A case of unresectable non-small cell lung cancer with pleural dissemination successfully treated with DIF]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:5 Topics: Adenocarcinoma, Papillary; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Female; Humans; Lung Neoplasms; Oxonic Acid; Pleural Effusion, Malignant; Pyridines; Quality of Life; Tegafur; Uracil	2006
[A case of recurrent pancreatic cancer responding to TS-1 combined gemcitabine chemotherapy after UFT combined gemcitabine chemotherapy resulting progressive disease]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Female; Gemcitabine; Humans; Jaundice, Obstructive; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pancreatic Neoplasms; Pyridines; Quality of Life; Remission Induction; Tegafur; Uracil	2006
[A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7 Topics: Adult; Anorexia; Antimetabolites, Antineoplastic; Bone Neoplasms; Cerebral Hemorrhage; Dihydropyrimidine Dehydrogenase Deficiency; Drug Combinations; Fatal Outcome; Humans; Liver Neoplasms; Male; Nausea; Oxonic Acid; Stomach Neoplasms; Tegafur; Uracil	2006
[Antitumor activity and function of S-1, a new oral tegafur-based formulation]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1 Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Neoplasms; Oxonic Acid; Pharmaceutical Preparations; Rats; Sarcoma, Yoshida; Tegafur; Uracil	2006
[Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1 Topics: beta-Alanine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Kidney; Oxonic Acid; Stomach Neoplasms; Tegafur; Uracil	2006
[A case of gemcitabine-based chemo-radiation therapy for locally advanced unresectable pancreatic cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:11 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Gemcitabine; Humans; Male; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Quality of Life; Radiotherapy Dosage; Survivors; Tegafur; Uracil	2006
[A resected case of squamous cell carcinoma of the breast successfully treated by FU plus cisplatin (CDDP) adjuvant therapy against recurrent metastases]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Mastectomy; Neoplasm Invasiveness; Oxonic Acid; Skin Neoplasms; Tegafur; Uracil	2007
[A case of liver metastasis of gastric cancer undergoing non-curative operation responding completely to combination therapy of S-1 and CDDP]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Gastrectomy; Humans; Liver Neoplasms; Male; Neoplasm Staging; Oxonic Acid; Quality of Life; Stomach Neoplasms; Tegafur; Uracil	2007
[A case of breast metastasis of gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Signet Ring Cell; Cisplatin; Drug Combinations; Female; Gastrectomy; Humans; Lymphatic Metastasis; Middle Aged; Neoplastic Cells, Circulating; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Tegafur; Uracil	2007
[Two cases of stage IV gastric cancer responding to chemotherapy with S-1 or UFT]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:9 Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Humans; Male; Middle Aged; Oxonic Acid; Stomach Neoplasms; Tegafur; Uracil	2007
[A long-term surviving patient with unresectable lung metastasis from colon cancer treated with intravenous administration of activated autologous lymphocytes and low-dose chemotherapy--a case report]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:12 Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Female; Humans; Immunotherapy; Injections, Intravenous; Irinotecan; Lung Neoplasms; Lymphocyte Activation; Lymphocyte Transfusion; Lymphocytes; Oxonic Acid; Sigmoid Neoplasms; Tegafur; Time Factors; Tomography, X-Ray Computed; Transplantation, Autologous; Uracil	2007
[Study of a relationship between a change in the urinary uracil value after a S-1 long-term administration and the recurrence of stomach cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:6 Topics: Aged; Drug Combinations; Female; Health; Humans; Male; Middle Aged; Oxonic Acid; Recurrence; Stomach Neoplasms; Tegafur; Time Factors; Uracil	2008
Gemcitabine-based versus fluoropyrimidine-based chemotherapy with or without platinum in unresectable biliary tract cancer: a retrospective study. BMC cancer, 2008, Dec-18, Volume: 8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Cisplatin; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Gemcitabine; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Palliative Care; Pyrimidinones; Retrospective Studies; Tegafur; Treatment Outcome; Uracil	2008
Pharmacokinetic study of S-1. International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:1 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Area Under Curve; beta-Alanine; Biological Availability; Clinical Trials as Topic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fasting; Fluorouracil; Food; Gastric Acidity Determination; Half-Life; Humans; Hydrogen-Ion Concentration; Oxonic Acid; Pantoprazole; Pyridines; Tegafur; Triazines; Uracil	2009
Vascular endothelial growth factor receptor expression as a prognostic marker for survival in colorectal cancer. Japanese journal of clinical oncology, 2009, Volume: 39, Issue:9 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Leucovorin; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Retrospective Studies; Survival Rate; Tegafur; Uracil; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3	2009
[A case of anaplastic carcinoma of thyroid administered peroral fluorinated pyrimidine for long-term survival during three years]. Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:6 Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Combinations; Female; Humans; Oxonic Acid; Tegafur; Thyroid Neoplasms; Uracil	2009
[Gemcitabine in combination with S-1 or UFT in patients with advanced pancreatic cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Combinations; Female; Gemcitabine; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Pancreatic Neoplasms; Retrospective Studies; Survival Rate; Tegafur; Uracil	2009
Can the 2-(13)C-uracil breath test be used to predict the effect of the antitumor drug S-1? Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:2 Topics: Aged; Aged, 80 and over; Alleles; Antineoplastic Combined Chemotherapy Protocols; Aryl Hydrocarbon Hydroxylases; Breath Tests; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Drug Combinations; Female; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasms; Oxonic Acid; Polymorphism, Genetic; Predictive Value of Tests; Prognosis; Radiopharmaceuticals; Tegafur; Uracil	2010
[A case of effective chemotherapy using S-1 and CPT-11 following chemoradiotherapy with UFT and Leucovorin for unresectable advanced sigmoid colon cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:3 Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Combinations; Humans; Irinotecan; Leucovorin; Male; Oxonic Acid; Sigmoid Neoplasms; Tegafur; Uracil	2010
[Successful management with S-1 of recurrent gastric cancer after adjuvant chemotherapy with paclitaxel/UFT]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:4 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Oxonic Acid; Paclitaxel; Recurrence; Remission Induction; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed; Uracil	2010
Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV. Cancer science, 2010, Volume: 101, Issue:8 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug Combinations; Drug Evaluation, Preclinical; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Mice; Middle Aged; Oxonic Acid; Tegafur; Uracil; Xenograft Model Antitumor Assays	2010
Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer. Radiation oncology (London, England), 2010, Jun-03, Volume: 5 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphocyte Count; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxonic Acid; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Survival Rate; Tegafur; Treatment Outcome; Uracil	2010
Oral fluoropyrimidine may augment the efficacy of aromatase inhibitor via the down-regulation of estrogen receptor in estrogen-responsive breast cancer xenografts. Breast cancer research and treatment, 2011, Volume: 128, Issue:2 Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Proliferation; Doxorubicin; Drug Combinations; Estrogen Receptor alpha; Estrogens; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Oxonic Acid; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tegafur; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured; Uracil	2011
[An elderly patient with advanced gastric cancer maintaining complete response for over 3 years by oral administration of UFT following short span of S-1]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12 Topics: Adenocarcinoma; Administration, Oral; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Humans; Oxonic Acid; Remission Induction; Stomach Neoplasms; Tegafur; Uracil	2010
[A case of ovarian metastasis from colon cancer successfully treated with multidisciplinary therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12 Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combinations; Female; Humans; Hysterectomy; Krukenberg Tumor; Ovarian Neoplasms; Ovariectomy; Oxonic Acid; Sigmoid Neoplasms; Tegafur; Uracil	2010
[A case of local relapsed rectal cancer responding to low-dose S-1]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12 Topics: Administration, Oral; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Humans; Male; Neoplasm Recurrence, Local; Oxonic Acid; Rectal Neoplasms; Tegafur; Uracil	2010
[The feasibility of oral fluoropyrimidines as adjuvant chemotherapy after resection and local coagulation therapy of colorectal liver metastases]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:11 Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Combinations; Electrocoagulation; Female; Humans; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Survival Rate; Tegafur; Uracil	2011
[Oral antineoplastic agents for prostate cancer]. Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 5 Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Estramustine; Humans; Male; Oxonic Acid; Prostatic Neoplasms; Tegafur; Uracil	2011
Prognostic effects of oral anti-cancer drugs as adjuvant chemotherapy for 2 years after gastric cancer surgery. Surgery today, 2012, Volume: 42, Issue:8 Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Gastrectomy; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Oxonic Acid; Prognosis; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil	2012
[Pharmacokinetics of S-1 capsule in patients with advanced gastric cancer]. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:10 Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capsules; Drug Combinations; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur; Uracil	2012
The prognostic nutritional index predicts long-term outcomes of gastric cancer patients independent of tumor stage. Annals of surgical oncology, 2013, Volume: 20, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Gastrectomy; Humans; Lymphatic Metastasis; Lymphocyte Count; Male; Middle Aged; Nutritional Status; Oxonic Acid; Predictive Value of Tests; Retrospective Studies; Serum Albumin; Stomach Neoplasms; Tegafur; Time Factors; Uracil; Young Adult	2013
[A case of metastatic acsending colon cancer showing sustained complete response to chemotherapy with SOX and followed UFT]. Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:7 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; Humans; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Quality of Life; Tegafur; Tomography, X-Ray Computed; Uracil	2013
[Salvage therapy for castration-refractory prostate cancer resistant to docetaxel]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2013, Volume: 104, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Docetaxel; Drug Combinations; Drug Resistance, Neoplasm; Etoposide; Humans; Male; Middle Aged; Oxonic Acid; Paclitaxel; Prostatic Neoplasms, Castration-Resistant; Salvage Therapy; Streptonigrin; Taxoids; Tegafur; Uracil	2013
Reply to the letter to the editor 'Is fluoropyrimidindes without oxaliplatin optimal for the adjuvant treatment of mainstream stage III colon cancer?' by Abali et al. Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; Humans; Leucovorin; Male; Oxonic Acid; Tegafur; Uracil	2015
Is fluoropyrimidindes without oxaliplatin optimal for the adjuvant treatment of mainstream stage III colon cancer? Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; Humans; Leucovorin; Male; Oxonic Acid; Tegafur; Uracil	2015
Multicenter observational cohort study of post-operative treatment for completely resected non-small-cell lung cancer of pathological Stage I (T1 >2 cm and T2 in TNM classification version 6). Japanese journal of clinical oncology, 2015, Volume: 45, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cohort Studies; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Patient Selection; Postoperative Period; Prodrugs; Proportional Hazards Models; Tegafur; Uracil	2015
The association between the duration of fluoropyrimidine-based adjuvant chemotherapy and survival in stage II or III gastric cancer. World journal of surgical oncology, 2016, Apr-02, Volume: 14 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Female; Floxuridine; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prognosis; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Time Factors; Uracil	2016
Increase in Gene Expression of TYMP, DPYD and HIF1A Are Associated with Response to Preoperative Chemoradiotherapy Including S-1 or UFT for Rectal Cancer. Anticancer research, 2016, Volume: 36, Issue:5 Topics: Adult; Aged; Chemoradiotherapy; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Oxonic Acid; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tegafur; Thymidine Phosphorylase; Uracil	2016
Fluoropyrimidines and DPD testing: is there truly an inexorable link? European journal of cancer (Oxford, England : 1990), 2019, Volume: 113 Topics: Antineoplastic Agents; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Genotype; Humans; Neoplasms; Oxonic Acid; Pharmacogenomic Testing; Phenotype; Point-of-Care Testing; Pyrrolidines; Tegafur; Thymine; Trifluridine; Uracil	2019
Adjuvant tegafur-uracil (UFT) or S-1 monotherapy for advanced gastric cancer: a single center experience. World journal of surgical oncology, 2021, Apr-17, Volume: 19, Issue:1 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cohort Studies; Disease-Free Survival; Drug Combinations; Female; Humans; Middle Aged; Neoplasm Staging; Oxonic Acid; Prognosis; Stomach Neoplasms; Tegafur; Treatment Outcome; Uracil	2021