uracil and methotrexate

uracil has been researched along with methotrexate in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (35.82)	18.7374
1990's	19 (28.36)	18.2507
2000's	18 (26.87)	29.6817
2010's	6 (8.96)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, WY; Kim, DJ; Nam, HW; Youn, JH	1
Irie, G; Kamada, T; Matsuoka, Y; Shirato, H; Takamura, A; Tsuji, H; Tsujii, H	1
Kusuyama, H; Numa, H; Okada, K; Sakamoto, S	1
Irie, G; Kamada, T; Matsuoka, Y; Takamura, A; Tsuji, H; Tsujii, H; Usubuchi, H	1
Aprelikova, ON; Tomilin, NV	1
Beck, WR; Chang, JD; Isselbacher, EM; Nusbaum, NJ; Wright, GE	1
Abe, T; Horiike, S; Inazawa, J; Misawa, S; Nishigaki, H; Okuda, T; Taniwaki, M; Tsuji, H; Yashige, H; Yokota, S	1
Fraser, DC; Pearson, CK	1
Leĭkina, FI; Smolianskaia, AZ	1
Grossowicz, N; Mandelbaum-Shavit, F	1
Kummer, D	1
Viola, MV	1
Ankermann, H; Bauer, B; Klinger, W; Traeger, A	1
Hoshi, A; Kanzawa, F; Kumagai, K; Kuretani, K	1
Calman, N; Eng, B; Slater, LM; Wallerstein, H	1
Oriuchi, T	1
Zeuthen, E	1
Tschiersch, B	1
Mardiak, J; Reiner, P; Reinerová, M; Ujházy, V	1
Santi, DV	1
Demachi, H; Konishi, K; Kuroda, Y; Tsugawa, K; Tsuji, M; Yabushita, K	1
Allegra, CJ; Grogan, L; Sotos, GA	1
Henson, E; McClarty, G; Wang, LL	1
Ikeda, K; Shibata, N; Tamai, M	1
Ames, BN; Blount, BC	2
Chio, LC; Queener, SF	1
Iida, A; Ikeda, N; Komatsu, T; Ookubo, K	1
Fida, S; Wickramasinghe, SN	1
Bregliano, JC; Degroote, F; Laurençon, A	1
Fujii, M; Fukuda, S; Inuyama, Y; Kawasaki, K; Kawaura, M; Kohno, N; Tanaka, K	1
DeGoeij, K; Mester, J; Sluyser, M	1
Inaji, H; Koyama, H; Motomura, K; Noguchi, S	1
Hata, K; Kaganoi, J; Nanbu, H; Nishitai, R; Ohsumi, K; Tokunaga, Y	1
Codes, M; Dugue, A; Garcia, E; Iglesias, L; Moreno, JA; Murillo, E; Torrija, E; Virizuela, JA	1
Ayala, F; Casado, A; Diaz-Rubio, E; López-Martin, JA; Martin, M; Nieto, Y; Rodriguez-Lescure, A	1
Watanabe, T	2
Ajani, JA; Yao, JC	1
Ando, J; Fujisaki, M; Ikeda, T; Imoto, S; Kobayashi, H; Kojima, M; Oka, S; Tamura, H; Wada, N	1
Kitaoka, A; Ohsumi, K; Tokuka, A; Tokunaga, Y; Yagi, T	1
Casado, A; Diaz-Rubio, E; Garcia-Carbonero, I; Garcia-Saenz, JA; Macias, JA; Manrique, I; Martín, M; Oruezabal, M	1
Ishikawa, T; Matsui, S; Matsuki, H; Matsuzawa, J; Mita, Y; Sato, S; Tashiro, K; Tashiro, S	1
Ishikawa, T; Kobayashi, M; Matsuki, H; Mita, Y; Tashiro, K; Tashiro, S	1
Ioka, Z; Nakane, Y; Nakano, K; Osaka, Y; Sako, H; Takemura, N; Tanabe, S; Tsuchiya, K	2
Ito, T; Nakamura, A; Sato, A; Taguchi, S; Tomita, T	1
Shimizu, C; Watanabe, T	1
HALL, TC	1
INNES, J	1
MORSE, PA; POTTER, VR	1
LAMBE, RF; WILLIAMS, DC	1
WELCH, AD	1
Au, GK; Chan, RT; Cheng, AC; Choy, DD; Chua, DT; Kwok, CC; Kwong, DL; Kwong, PW; Law, MW; Sham, JS; Wan, KY; Wu, PM; Yau, CC	1
Ishikawa, T; Kamimura, T; Mizuno, K; Ohta, H; Seki, K; Togashi, T; Watanabe, K; Yoshida, T	2
Hamada, T; Ichimura, W; Minagawa, N; Mino, K; Naito, H; Orimo, T; Shibazaki, W; Shinohara, T	1
Hanamura, H; Horiuchi, C; Kawakami, M; Matsuda, H; Mikami, Y; Nishimura, G; Satake, K; Taguchi, T; Takahashi, M; Tsukuda, M; Utsumi, A; Watanabe, M	1
Iwata, H; Kitaya, T; Kohno, N; Nakagami, K; Ohashi, Y; Sakamoto, G; Sano, M; Shimozuma, K; Sonoo, H; Takashima, S; Tokuda, Y; Tsuda, H; Watanabe, T; Yoshimoto, M	1
Asaga, T; Higaki, K; Inaji, H; Ito, T; Koh, J; Kohno, N; Komichi, H; Koyama, H; Kyono, S; Mitsuyama, S; Nishikawa, H; Ogita, M; Okamura, K; Osaki, A; Park, Y; Saito, T; Suzuki, T; Tanaka, F; Yamazaki, K	1
Inaji, H; Koyama, H; Ohashi, Y; Sano, M; Suzuki, T; Watanabe, T	1
Nakayama, T; Noguchi, S	1
Guo, R; Jiang, L; Li, J; Xu, D; Yu, L; Zhao, J	1
Bielecka-Kowalska, A; Bieniek, A; Cuchra, M; Dziki, L; Kowalski, M; Majsterek, I; Markiewicz, L; Mlynarski, W; Pastorczak, A; Sliwinski, T; Stanczyk, M; Szemraj, J; Trelinska, J	1
Fushimi, K; Takami, M; Tanabe, N	1

Reviews

10 review(s) available for uracil and methotrexate

Article	Year
Uracil-DNA glycosylases and DNA uracil repair. International review of cytology, 1989, Volume: 114 Topics: Animals; Bacillus subtilis; Chromosomes; DNA Glycosylases; DNA Ligases; DNA Repair; DNA, Bacterial; Escherichia coli; Humans; Methotrexate; Mutation; N-Glycosyl Hydrolases; Uracil; Uracil Nucleotides; Uracil-DNA Glycosidase	1989
[Metabolic modulation as a method in tumor chemotherapy]. Die Pharmazie, 1982, Volume: 37, Issue:7 Topics: Antineoplastic Agents; Cytarabine; Fluorouracil; Humans; Methotrexate; Neoplasms; Tegafur; Thymidine; Uracil	1982
Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase. Journal of medicinal chemistry, 1980, Volume: 23, Issue:2 Topics: Antineoplastic Agents; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Thymidylate Synthase; Uracil	1980
Preclinical and clinical aspects of biomodulation of 5-fluorouracil. Cancer treatment reviews, 1994, Volume: 20, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine	1994
[Head and neck cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Tegafur; Uracil	1996
[Benefits of adjuvant chemotherapy for breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Mitomycin; Randomized Controlled Trials as Topic; Tamoxifen; Tegafur; Uracil	1997
Preoperative therapy for local-regional gastric cancer: rationale and review of trials. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27 Suppl 2 Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Doxorubicin; Etoposide; Fluorouracil; Humans; Methotrexate; Mitomycin; Preoperative Care; Stomach Neoplasms; Tegafur; Uracil	2000
[Chemotherapy of gastric cancer--a review of clinical trials in Japan]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Drug Combinations; Floxuridine; Humans; Japan; Methotrexate; Mitomycin; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil	2002
[Recent advance in adjuvant therapy for breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:13 Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tamoxifen; Tegafur; Uracil	2002
Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan. The oncologist, 2010, Volume: 15, Issue:1 Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Japan; Methotrexate; Oxonic Acid; Tegafur; Uracil	2010

Trials

10 trial(s) available for uracil and methotrexate

Article	Year
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study. Journal of surgical oncology, 1997, Volume: 66, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Mitomycin; Postoperative Period; Rectal Neoplasms; Survival Rate; Tegafur; Uracil	1997
UFT in combination as adjuvant therapy for breast cancer. Grupo Oncologico de Sevilla Seville, Spain. Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Postmenopause; Prednimustine; Premenopause; Spain; Survival Analysis; Tamoxifen; Tegafur; Uracil	1997
Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral UFT (uracil/tegafur) versus six-cycle CMF (cyclophosphamide/methotrexate/5-fluorouracil) in high-risk node-negative breast cancer patients. Japanese journal of clinical oncology, 1998, Volume: 28, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Tegafur; Uracil	1998
Phase III randomized comparison of postoperative adjuvant chemotherapy with 2-year oral uracil/tegafur versus 6-cycle cyclophosphamide/methotrexate/5-fluorouracil in high-risk node-negative breast cancer patients. Cancer chemotherapy and pharmacology, 1998, Volume: 42 Suppl Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Risk; Survival Analysis; Tegafur; Uracil	1998
[Randomized comparative study of CMF (cyclophosphamide, methotrexate and 5-fluorouracil) and UFT-tamoxifen regimens as adjuvant chemotherapy after surgery for breast cancer: Tochigi Prefectural Study Group for Post-Breast Cancer Adjuvant Chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:7 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Prospective Studies; Quality of Life; Survival Rate; Tamoxifen; Tegafur; Uracil	2000
Methotrexate, uracil and tegafur, and leucovorin chemotherapy for patients with breast cancer in progression after high-dose chemotherapy with peripheral blood progenitor cell transplant: a phase II study. American journal of clinical oncology, 2000, Volume: 23, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Salvage Therapy; Survival Analysis; Tegafur; Uracil	2000
Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jul-01, Volume: 22, Issue:13 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Tegafur; Treatment Outcome; Uracil; Vincristine	2004
Oral uracil and tegafur compared with classic cyclophosphamide, methotrexate, fluorouracil as postoperative chemotherapy in patients with node-negative, high-risk breast cancer: National Surgical Adjuvant Study for Breast Cancer 01 Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-20, Volume: 27, Issue:9 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Quality of Life; Risk Factors; Tegafur; Uracil	2009
Uracil-tegafur and tamoxifen vs cyclophosphamide, methotrexate, fluorouracil, and tamoxifen in post-operative adjuvant therapy for stage I, II, or IIIA lymph node-positive breast cancer: a comparative study. British journal of cancer, 2009, Aug-18, Volume: 101, Issue:4 Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Staging; Survival Rate; Tamoxifen; Tegafur; Uracil	2009
Efficacy of oral tegafur-uracil (UFT) as adjuvant therapy as compared with classical cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in early breast cancer: a pooled analysis of two randomized controlled trials (N.SAS-BC 01 trial and CUBC trial). Breast cancer research and treatment, 2010, Volume: 119, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Receptors, Estrogen; Tegafur; Uracil; Young Adult	2010

Other Studies

47 other study(ies) available for uracil and methotrexate

Article	Year
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effects of pyrimidine salvage inhibitors on uracil incorporation of Toxoplasma gondii. Kisaengch'unghak chapchi. The Korean journal of parasitology, 1990, Volume: 28, Issue:2 Topics: Animals; DNA; Folic Acid Antagonists; Methotrexate; Pyrimethamine; Thymidylate Synthase; Toxoplasma; Uracil; Uridine	1990
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Tegafur; Uracil	1987
[Lung metastases of prostatic cancer vanished by early combined hormonal and chemotherapy: report of a case]. Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:6 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Estramustine; Humans; Lung Neoplasms; Male; Methotrexate; Orchiectomy; Prostatic Neoplasms; Proteoglycans; Tegafur; Uracil	1989
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy. Cancer, 1989, May-01, Volume: 63, Issue:9 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Tegafur; Uracil	1989
Enhancement of methotrexate cytotoxicity by uracil analogues that inhibit deoxyuridine triphosphate nucleotidohydrolase (dUTPase) activity. Advances in experimental medicine and biology, 1986, Volume: 195 Pt B Topics: Animals; Cattle; Cell Cycle; Cell Survival; Cells, Cultured; DNA; DNA Glycosylases; Humans; In Vitro Techniques; Methotrexate; Mice; N-Glycosyl Hydrolases; Pyrophosphatases; Thymine Nucleotides; Uracil; Uracil-DNA Glycosidase	1986
[Improved quality of life in a patient with Borrmann type 4 gastric cancer treated with combination chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:6 Pt 1 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Picibanil; Prognosis; Quality of Life; Stomach Neoplasms; Tegafur; Uracil	1987
Is uracil misincorporation into DNA of mammalian cells a consequence of methotrexate treatment? Biochemical and biophysical research communications, 1986, Mar-28, Volume: 135, Issue:3 Topics: Cell Line; Chromatography, High Pressure Liquid; DNA; Humans; Methotrexate; Uracil	1986
[Detection of a moderate staphylococcal phage by means of antineoplastic agents]. Antibiotiki, 1970, Volume: 15, Issue:6 Topics: Aminopterin; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antimetabolites; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Dactinomycin; Drug Resistance, Microbial; Flavonoids; Fluorouracil; Lysogeny; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Olivomycins; Staphylococcus; Staphylococcus Phages; Thiotepa; Ultraviolet Rays; Uracil; Vinblastine; Vincristine	1970
Effect of folinate on thymidine uptake by Pediococcus cerevisiae. Journal of bacteriology, 1968, Volume: 95, Issue:4 Topics: Aminopterin; Carbon Isotopes; Deoxyuridine; Floxuridine; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Leucovorin; Methotrexate; Pediococcus; Temperature; Thymidine; Thymine; Tritium; Uracil	1968
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro]. Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1 Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine	1970
Acute leukemia and infection. JAMA, 1967, Sep-18, Volume: 201, Issue:12 Topics: Acute Disease; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Aspergillosis; Candidiasis; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mucormycosis; Nocardia Infections; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Strongyloidiasis; Uracil; Vinblastine	1967
The influence of alkylants, antimetabolites and chloroquine on oxydative biotransformation reactions and on the excretion of ascorbic acid in the rat. Acta biologica et medica Germanica, 1973, Volume: 30, Issue:3 Topics: Alkylating Agents; Animals; Antimetabolites; Ascorbic Acid; Biotransformation; Chloroquine; Cyclophosphamide; Liver; Male; Mercaptopurine; Methotrexate; Oxidation-Reduction; Rats; Triazines; Uracil	1973
Sensitivity of Nakahara-Fukuoka sarcoma to antitumor agents, especially to purine analogs. Gan, 1969, Volume: 60, Issue:1 Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Fluorouracil; Hydrocortisone; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitomycins; Purines; Sarcoma, Experimental; Thioguanine; Thiotepa; Uracil	1969
Reversal of resistance to methotrexate in L1210 murine leukemia by uracil. Blood, 1971, Volume: 38, Issue:5 Topics: Animals; DNA; Drug Resistance; Leukemia L1210; Mercaptopurine; Methotrexate; Nucleic Acids; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium; Uracil	1971
[On uptake of 5-FU, 6-MP and methotrexate by ehrlich ascites tumor cells in vitro]. Sapporo igaku zasshi. The Sapporo medical journal, 1970, Volume: 37, Issue:6 Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Fluorouracil; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Mice; Sulfur Isotopes; Time Factors; Tritium; Uracil	1970
Thymine starvation by inhibition of uptake and synthesis of thymine-compounds in Tetrahymena. Experimental cell research, 1968, Volume: 50, Issue:1 Topics: Cell Division; DNA; Hot Temperature; Methotrexate; Nucleosides; Tetrahymena; Thymidine; Thymine; Tritium; Uracil; Uracil Nucleotides; Uridine	1968
Inhibition of colony-forming cells from bone marrow of leukemic patients by 3-oxauracil. Neoplasma, 1981, Volume: 28, Issue:5 Topics: Antimetabolites; Bone Marrow; Cells, Cultured; Cisplatin; Colony-Forming Units Assay; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Oxazines; Uracil	1981
[A case of gastric cancer responding well to MTX/5-FU (methotrexate/5-fluorouracil) and PMUE (CDDP, MMC, UFT, etoposide) therapies upon lymphnode recurrence]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:13 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Stomach Neoplasms; Tegafur; Uracil	1995
Characterization of trimethoprim- and sulphisoxazole-resistant Chlamydia trachomatis. Molecular microbiology, 1994, Volume: 14, Issue:2 Topics: Adenosine Triphosphate; Animals; Chlamydia trachomatis; DNA, Bacterial; Drug Resistance, Microbial; Fluorouracil; Guanosine Triphosphate; L Cells; Methotrexate; Mice; Microbial Sensitivity Tests; Mutation; Phenotype; RNA, Bacterial; Sulfisoxazole; Thymidine; Trimethoprim; Uracil; Zidovudine	1994
[Case report of long-term survivor of advanced gastric cancer associated with peritoneal dissemination successfully treated with cancer chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:1 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Methotrexate; Peritoneal Neoplasms; Prognosis; Stomach Neoplasms; Tegafur; Uracil	1995
Analysis of uracil in DNA by gas chromatography-mass spectrometry. Analytical biochemistry, 1994, Volume: 219, Issue:2 Topics: Animals; Benzyl Compounds; DNA; DNA, Bacterial; Escherichia coli; Gas Chromatography-Mass Spectrometry; Hepatectomy; Indicators and Reagents; Liver; Liver Regeneration; Male; Methotrexate; Rats; Rats, Inbred F344; Uracil	1994
Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9 Topics: Animals; CHO Cells; Cricetinae; Dihydropteroate Synthase; Female; Folic Acid Antagonists; Methotrexate; Mice; Mice, Inbred ICR; Toxoplasma; Trimetrexate; Uracil	1993
Development of a sensitive assay for detection of uracil in DNA. Advances in experimental medicine and biology, 1993, Volume: 338 Topics: Animals; DNA; Folic Acid; Folic Acid Deficiency; Indicators and Reagents; Liver; Mass Spectrometry; Methotrexate; Microchemistry; Rats; Rats, Inbred F344; Uracil	1993
[A case of advance colon cancer responding to sequential methotrexate and 5-fluorouracil therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:5 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Remission Induction; Tegafur; Uracil	1993
Misincorporation of uracil into the DNA of folate- and B12-deficient HL60 cells. European journal of haematology, 1993, Volume: 50, Issue:3 Topics: Chromatography, Ion Exchange; DNA, Neoplasm; Folic Acid; Humans; Leukemia, Promyelocytic, Acute; Methotrexate; Tritium; Tumor Cells, Cultured; Uracil; Vitamin B 12	1993
Evidence for an inducible repair-recombination system in the female germ line of Drosophila melanogaster. I. Induction by inhibitors of nucleotide synthesis and by gamma rays. Genetics, 1995, Volume: 141, Issue:2 Topics: Aging; Animals; Antimetabolites; Cesium Radioisotopes; DNA Repair; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Fertility; Gamma Rays; Kinetics; Male; Methotrexate; Oocytes; Oviposition; Recombination, Genetic; Retroelements; Time Factors; Uracil	1995
Modulation of [5-125I]iododeoxyuridine incorporation into tumour and normal tissue DNA by methotrexate and thymidylate synthase inhibitors. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9 Topics: Animals; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Female; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Radioisotopes; Liver; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Thiophenes; Thymidylate Synthase; Uracil	1996
Preliminary results. UFT/methotrexate/leucovorin for breast Ca patients in progression after HDCT/PBPC support. Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10 Topics: Adult; Anemia; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diarrhea; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neutropenia; Survival Rate; Tegafur; Uracil	1997
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for stages 3 and 4 gastric carcinoma: A preliminary study. Journal of surgical oncology, 2000, Volume: 75, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Stomach Neoplasms; Survival Rate; Tegafur; Uracil	2000
[A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with angiotensin-II and administration of tegafur/uracil]. Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:4 Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Tegafur; Uracil	2001
[A case of nonresectable scirrhous type gastric cancer treated by hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:8 Topics: Adenocarcinoma, Scirrhous; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Drug Administration Schedule; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tegafur; Uracil	2001
[A case of gastric cancer with paraaortic lymph node metastasis responding to preoperative chemotherapy and surviving 4 years and 4 months after total gastrectomy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4 Topics: Adenocarcinoma, Scirrhous; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Stomach Neoplasms; Survivors; Tegafur; Uracil	2002
[A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Leucovorin; Liver Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms; Tegafur; Uracil	2002
A comparative study of 5-fluorouracil (FU), 5-fluorodeoxyuridine (FUDR), and methotrexate (MTX)-progress report. Cancer chemotherapy reports, 1962, Volume: 16 Topics: Antineoplastic Agents; Floxuridine; Fluorouracil; Folic Acid Antagonists; Methotrexate; Nucleosides; Nucleotides; Research Report; Uracil	1962
ANTI-LEUKAEMIC DRUGS. The Practitioner, 1964, Volume: 193 Topics: Busulfan; Chlorambucil; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mustard Plant; Neoplasms; Splenomegaly; Steroids; Uracil	1964
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA. Cancer research, 1965, Volume: 25 Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil	1965
THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLIC DRUGS. The Biochemical journal, 1965, Volume: 95 Topics: Aminopterin; Antimetabolites; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Mercaptopurine; Methotrexate; NAD; Oxidoreductases; Research; Steroids; Testosterone; Uracil	1965
[SOME MECHANISMS AND PROBLEMS OF SELECTIVE CHEMOTHERAPY]. Deutsche medizinische Wochenschrift (1946), 1965, Sep-03, Volume: 90 Topics: Antineoplastic Agents; Drug Therapy; Humans; Methotrexate; Neoplasms; Nucleosides; Uracil; Uridine	1965
[Modified pharmacokinetic modulating chemotherapy for progressive gastric cancer accompanied by peritoneal dissemination]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate; Tegafur; Uracil	2005
[A case of advanced gastric cancer with bone metastasis and severe DIC responding to hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4 Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Signet Ring Cell; Disseminated Intravascular Coagulation; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Methotrexate; Middle Aged; Paclitaxel; Quality of Life; Stomach Neoplasms; Tegafur; Uracil	2005
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combinations; Floxuridine; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Neoplasm Staging; Picibanil; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil	2005
The efficacy and safety of concurrent chemoradiotherapy for maxillary sinus squamous cell carcinoma patients. Auris, nasus, larynx, 2009, Volume: 36, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoadjuvant Therapy; Organ Preservation; Paranasal Sinus Neoplasms; Retrospective Studies; Tegafur; Treatment Outcome; Uracil	2009
Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans. FEMS yeast research, 2010, Volume: 10, Issue:2 Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Carbon-Nitrogen Ligases; Fungal Proteins; Gene Expression Regulation, Fungal; Humans; Male; Methotrexate; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Phosphoribosylglycinamide Formyltransferase; Purines; Uracil; Virulence	2010
Role of base-excision repair in the treatment of childhood acute lymphoblastic leukaemia with 6-mercaptopurine and high doses of methotrexate. Mutation research, 2012, Jan-24, Volume: 741, Issue:1-2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Child; Child, Preschool; Comet Assay; DNA Damage; DNA Repair; Humans; Hydrogen Peroxide; Lymphocytes; Male; Mercaptopurine; Methotrexate; Oxidation-Reduction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Uracil; Young Adult	2012
[A retrospective study of tegafur/uracil compared with cyclophosphamide, methotrexate, and fluorouracil as adjuvant chemotherapy in patients with node-negative, triple-negative breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Tegafur; Triple Negative Breast Neoplasms; Uracil	2014