uracil and glucose, (beta-d)-isomer

uracil has been researched along with glucose, (beta-d)-isomer in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19908 (13.33)18.7374
1990's11 (18.33)18.2507
2000's17 (28.33)29.6817
2010's20 (33.33)24.3611
2020's4 (6.67)2.80

Authors

AuthorsStudies
Hegazy, MI; Marquardt, RR1
Sardas, S; Vural, N1
Chevion, M; Navok, T1
Frohlich, AA; Marquardt, RR1
Bianco, VV; Lafiandra, D; Lattanzio, V1
Arese, P; Bosia, A; D'Aquino, M; Gaetani, GF; Gaetani, S; Naitana, A1
Arese, P; Sisini, A; Spanu, A1
Borst, P; Gommers-Ampt, JH1
Borst, P; Crain, PF; de Beer, AL; Dizdaroglu, M; Gommers-Ampt, JH; Kowalak, JA; Van Leeuwen, F; Vliegenthart, JF1
Borst, P; Kuyl-Yeheskiely, E; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wijsman, ER1
Borst, P; Kieft, R; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wijsman, ER1
Simpson, L1
Borst, P; Gibson, W; Kieft, R; Mondragon, A; Moreau, H; Taylor, MC; van Leeuwen, F1
Borst, P; van Leeuwen, F1
Borst, P; de Kort, M; van Boom, JH; van der Marel, GA; van Leeuwen, F1
Borst, P; Dirks, RW; Dirks-Mulder, A; Gibson, W; van Leeuwen, F1
Borst, P; Cross, M; Kieft, R; van Leeuwen, F2
Borst, P; Cross, M; de Kort, M; Kieft, R; Sabatini, R; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wilm, M1
Borst, P; Chaves, I; Dirks-Mulder, A; Dooijes, D; Kieft, R; Martin, W1
Borst, P; Meeuwenoord, N; Sabatini, R; van Boom, JH2
Boorstein, RJ; Borst, P; Cross, M; Teebor, GW; Ulbert, S1
Borst, P; Chaves, I; Cross, M; Dirks-Mulder, A; Kieft, R; Sabatini, R1
Borst, P; Eide, L; Seeberg, E; Ulbert, S1
McCulloch, R1
Cross, M; DiPaolo, C; Kieft, R; Sabatini, R1
Ju, JH; Yang, JS; Zou, ZJ1
Borst, P; Cijsouw, T; Genest, PA; Ter Riet, B; van Luenen, HG1
Borst, P; Christodoulou, E; DiPaolo, C; Genest, PA; Hausinger, RP; Kieft, R; Perrakis, A; Rigden, DJ; Sabatini, R; Simmons, JM; Sweeney, K; ter Riet, B; van Luenen, HG; Yu, Z1
Brand, V; DiPaolo, C; Ekanayake, DK; Kieft, R; Reznikoff, WS; Sabatini, R; Sweeney, K1
Cipriano, MJ; Ekanayake, DK; Sabatini, R1
Borst, P; Sabatini, R1
Borst, P; Genest, PA; ter Riet, B; Vainio, S; van Luenen, H1
Birkeland, SR; Cliffe, LJ; Kieft, R; Marshall, M; Sabatini, R; Southern, T; Sweeney, K1
Cliffe, LJ; Cross, GA; Marshall, M; Sabatini, R; Siegel, TN1
Borst, P; Chalmers, MJ; Christodoulou, E; Griffin, PR; Grover, RK; Heidebrecht, T; Jan, S; Joosten, RP; Littler, D; Perrakis, A; Ter Riet, B; van Luenen, H; Wentworth, P1
Ekanayake, D; Sabatini, R1
Borst, P; Fish, A; Heidebrecht, T; Johnson, KA; Perrakis, A; von Castelmur, E; Zaccai, G1
Deng, W; Ding, L; Jiang, S; Peng, S; Shi, H; Xu, K; Zhang, Y; Zhou, Y1
Borst, P; Farris, C; Genest, PA; Haydock, A; Heidebrecht, T; Jan, S; Kerkhoven, RM; Myler, PJ; Nieuwland, M; Pagie, L; Perrakis, A; Ramasamy, G; Tripathi, P; Vainio, S; van Luenen, HG; van Steensel, B; Velds, A1
Buratowski, S; Hazelbaker, DZ1
Bullard, W; Liu, S; Lopes da Rosa-Spiegler, J; Sabatini, R; Wang, Y1
Ji, D; Wang, Y1
Cliffe, L; Ji, D; Liu, S; Sabatini, R; Wang, Y1
Cliffe, L; Förstner, KU; Hon, CC; Reynolds, D; Sabatini, R; Siegel, TN1
Baugh, L; Boitano, M; Borst, P; Clark, T; Genest, PA; Jan, S; Korlach, J; Luong, K; Myler, PJ; Taipale, A; Turner, S; van Luenen, HG; Zhao, W1
Alabady, M; Cliffe, L; Hofmeister, BT; Reynolds, D; Sabatini, R; Schmitz, RJ; Siegel, TN1
Kim, HS; Papavasiliou, FN; Schulz, D; Zaringhalam, M1
Hirate, M; Kutoh, E; Murayama, T; Wada, A1
Anderson, BA; Beverley, SM; Cliffe, L; Hofmeister, BT; Reynolds, DL; Sabatini, R; Schmitz, RJ; Siegel, TN1
Hernández, C; Simó, R1
Balasubramanian, S; Beraldi, D; Hardisty, RE; Kawasaki, F; McInroy, GR; van Delft, P1
Lingvay, I1
Adamopoulos, A; Fish, A; Heidebrecht, T; Joosten, RP; Pardon, E; Perrakis, A; Steyaert, J; van Beusekom, B1
Bridger, R; Kieft, R; Marand, AP; Moran, JD; Sabatini, R; Schmitz, RJ; Wells, L; Zhang, Y1
Attia, SL; Mouzaki, M; Softic, S1
Nabavizadeh, P; Steen, DL1
Nanjappan, SK; Ravichandiran, V; Somabattini, RA1

Reviews

7 review(s) available for uracil and glucose, (beta-d)-isomer

ArticleYear
Hypermodified bases in DNA.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1995, Volume: 9, Issue:11

    Topics: Animals; Bacteriophages; DNA; DNA, Viral; Eukaryotic Cells; Glucosides; Prokaryotic Cells; Purines; Pyrimidines; Trypanosoma brucei brucei; Uracil

1995
A base called J.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Animals; DNA, Protozoan; Eukaryota; Evolution, Molecular; Glucosides; Humans; Repetitive Sequences, Nucleic Acid; Telomere; Thymine; Trypanosoma brucei brucei; Trypanosomiasis, African; Uracil; Variant Surface Glycoproteins, Trypanosoma

1998
beta-D-glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida.
    Molecular and biochemical parasitology, 1997, Dec-01, Volume: 90, Issue:1

    Topics: Animals; DNA Restriction Enzymes; DNA, Protozoan; Gene Expression Regulation; Genes, Protozoan; Glucosides; Kinetoplastida; Models, Genetic; Repetitive Sequences, Nucleic Acid; Trypanosoma; Trypanosoma brucei brucei; Uracil

1997
Antigenic variation in African trypanosomes: monitoring progress.
    Trends in parasitology, 2004, Volume: 20, Issue:3

    Topics: Animals; Antigenic Variation; Genetic Variation; Glucosides; Transcription, Genetic; Trypanosoma brucei brucei; Trypanosomiasis, African; Uracil; Variant Surface Glycoproteins, Trypanosoma

2004
Base J: discovery, biosynthesis, and possible functions.
    Annual review of microbiology, 2008, Volume: 62

    Topics: Animals; Base Sequence; DNA-Binding Proteins; DNA, Protozoan; Drug Discovery; Epigenesis, Genetic; Glucosides; Humans; Leishmania; Models, Biological; Protozoan Proteins; Trypanosoma brucei brucei; Uracil

2008
SODIUM GLUCOSE COTRANSPORTER 2 AND DIPEPTIDYL PEPTIDASE-4 INHIBITION: PROMISE OF A DYNAMIC DUO.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:7

    Topics: Adamantane; Benzhydryl Compounds; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glucosides; Humans; Hypoglycemia; Hypoglycemic Agents; Linagliptin; Metformin; Piperidines; Sitagliptin Phosphate; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome; Uracil

2017
Evolving Role for Pharmacotherapy in NAFLD/NASH.
    Clinical and translational science, 2021, Volume: 14, Issue:1

    Topics: Adult; Benzhydryl Compounds; Chenodeoxycholic Acid; Child; Clinical Trials, Phase III as Topic; Fibroblast Growth Factors; Glucosides; Humans; Imidazoles; Isobutyrates; Liraglutide; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Oxazoles; Polyethylene Glycols; Pyridazines; Pyrimidines; Severity of Illness Index; Sulfoxides; Treatment Outcome; Uracil

2021

Trials

1 trial(s) available for uracil and glucose, (beta-d)-isomer

ArticleYear
Ipragliflozin as an Initial Therapy in Drug Naïve Subjects with Type 2 Diabetes.
    Drug research, 2016, Volume: 66, Issue:7

    Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Piperidines; Prospective Studies; Thiophenes; Uracil

2016

Other Studies

52 other study(ies) available for uracil and glucose, (beta-d)-isomer

ArticleYear
Metabolism of vicine and convicine in rat tissues: absorption and excretion patterns and sites of hydrolysis.
    Journal of the science of food and agriculture, 1984, Volume: 35, Issue:2

    Topics: Animals; Glucosides; Glycosides; Hydrolysis; Intestinal Absorption; Male; Pyrimidinones; Rats; Rats, Inbred Strains; Uracil; Uridine

1984
Biological activities of broad bean (Vicia faba L.) extracts cultivated in South Anatolia in favism sensitive subjects.
    Toxicology, 1984, May-14, Volume: 31, Issue:2

    Topics: Fabaceae; Favism; Glucosides; Hemolysis; Humans; In Vitro Techniques; Plant Extracts; Plants, Medicinal; Pyrimidinones; Turkey; Uracil; Uridine

1984
A novel method for quantitation of favism-inducing agents in legumes.
    Analytical biochemistry, 1983, Volume: 128, Issue:1

    Topics: Barbiturates; Fabaceae; Favism; Glucosidases; Glucosides; Oxidation-Reduction; Phenanthrolines; Plants, Medicinal; Pyrimidinones; Spectrophotometry; Uracil; Uridine

1983
Turnover and hydrolysis of vicine and convicine in avian tissues and digesta.
    Journal of the science of food and agriculture, 1983, Volume: 34, Issue:2

    Topics: Absorption; Animals; Anti-Bacterial Agents; Cecum; Chickens; Glucosides; Glycosides; Half-Life; Hydrolysis; Intestines; Male; Pyrimidinones; Tissue Distribution; Uracil; Uridine

1983
Hingh-performance reversed-phase liquid chromatography (HPLC) of favism-inducing factors in Vicia faba L.
    Experientia, 1982, Jul-15, Volume: 38, Issue:7

    Topics: Chromatography, High Pressure Liquid; Fabaceae; Favism; Glucosides; Glycosides; Levodopa; Plants, Medicinal; Pyrimidinones; Seeds; Uracil; Uridine

1982
Effect of divicine and isouramil on red cell metabolism in normal and G6PD-deficient (Mediterranean variant) subjects. Possible role in the genesis of favism.
    Progress in clinical and biological research, 1981, Volume: 55

    Topics: Ascorbic Acid; Barbiturates; Erythrocytes; Favism; Glucosephosphate Dehydrogenase Deficiency; Glucosides; Glutathione; Humans; Kinetics; Pyrimidinones; Reference Values; Species Specificity; Toxins, Biological; Uracil; Uridine

1981
[Genetic improvement in Vicia faba and favism. I. Distribution and levels of presumably hemolytic metabolites].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Jul-30, Volume: 57, Issue:14

    Topics: Ascorbic Acid; Fabaceae; Favism; Glucosides; Hemolysin Proteins; Levodopa; Plants, Medicinal; Pyrimidinones; Seeds; Uracil; Uridine

1981
beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei.
    Cell, 1993, Dec-17, Volume: 75, Issue:6

    Topics: Animals; Chromatography, Liquid; Chromatography, Thin Layer; Deoxyribonucleotides; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Galactosyltransferases; Gas Chromatography-Mass Spectrometry; Gene Expression; Glucosides; Magnetic Resonance Spectroscopy; Molecular Structure; Telomere; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1993
The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands.
    Nucleic acids research, 1996, Jul-01, Volume: 24, Issue:13

    Topics: Animals; Base Sequence; DNA, Protozoan; DNA, Single-Stranded; Genome, Protozoan; Glucosides; Molecular Sequence Data; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Uracil

1996
Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei.
    Genes & development, 1997, Dec-01, Volume: 11, Issue:23

    Topics: Animals; Antibodies, Protozoan; Binding Sites; Deoxyribonucleases, Type II Site-Specific; DNA, Protozoan; Gene Expression; Genes, Protozoan; Glucosides; Precipitin Tests; Promoter Regions, Genetic; Rabbits; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1997
beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Animals; Base Sequence; Conserved Sequence; DNA, Protozoan; Eukaryota; Glucosides; Humans; Insecta; Leishmania donovani; Mammals; Phylogeny; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Trypanosoma cruzi; Uracil

1998
The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.
    Analytical biochemistry, 1998, May-01, Volume: 258, Issue:2

    Topics: Animals; Drug Resistance; Glucosides; Hydrolysis; Micrococcal Nuclease; Pyrimidines; Trypanosoma brucei brucei; Uracil

1998
The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.
    Molecular and biochemical parasitology, 1998, Jul-01, Volume: 94, Issue:1

    Topics: Animals; Antigenic Variation; DNA, Protozoan; Fluorescent Antibody Technique, Indirect; Glucosides; In Situ Hybridization, Fluorescence; Salivary Glands; Trypanosoma brucei brucei; Tsetse Flies; Uracil

1998
Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.
    Molecular and cellular biology, 1998, Volume: 18, Issue:10

    Topics: Animals; Base Pairing; Binding Sites; Bromodeoxyuridine; DNA; Gene Expression Regulation; Glucosides; Pentoxyl; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1998
The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans.
    The EMBO journal, 1999, Nov-15, Volume: 18, Issue:22

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Nucleus; Crithidia fasciculata; DNA-Binding Proteins; DNA, Protozoan; Gene Silencing; Glucosides; Kinetoplastida; Leishmania; Molecular Sequence Data; Protozoan Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1999
Base J originally found in kinetoplastida is also a minor constituent of nuclear DNA of Euglena gracilis.
    Nucleic acids research, 2000, Aug-15, Volume: 28, Issue:16

    Topics: Animals; Base Sequence; Cell Nucleus; Chromatography, Thin Layer; DNA Primers; DNA, Protozoan; Euglena gracilis; Glucosides; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Trypanosoma brucei brucei; Uracil

2000
Tandemly repeated DNA is a target for the partial replacement of thymine by beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.
    Molecular and biochemical parasitology, 2000, Volume: 109, Issue:2

    Topics: Animals; DNA Transposable Elements; DNA, Protozoan; DNA, Ribosomal; Genes, Protozoan; Genes, rRNA; Glucosides; RNA, Ribosomal, 5S; RNA, Spliced Leader; Tandem Repeat Sequences; Telomere; Thymine; Trypanosoma brucei brucei; Uracil

2000
Recognition of base J in duplex DNA by J-binding protein.
    The Journal of biological chemistry, 2002, Jan-11, Volume: 277, Issue:2

    Topics: Animals; Crithidia fasciculata; DNA; DNA-Binding Proteins; Glucosides; Molecular Structure; Oligonucleotides; Protein Binding; Protozoan Proteins; Recombinant Proteins; Uracil

2002
Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts.
    The Journal of biological chemistry, 2002, Aug-02, Volume: 277, Issue:31

    Topics: Animals; Base Sequence; Binding Sites; Crithidia; DNA Methylation; DNA-Binding Proteins; DNA, Protozoan; Glucosides; Leishmania; Models, Molecular; Nucleic Acid Conformation; Protozoan Proteins; Trypanosoma; Uracil

2002
Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis.
    Nucleic acids research, 2002, Sep-15, Volume: 30, Issue:18

    Topics: Animals; Cell Cycle; Cell Death; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Protozoan; Electrophoresis, Agar Gel; Gene Expression Regulation, Enzymologic; Glucosides; Humans; N-Glycosyl Hydrolases; Plasmids; Tetracycline; Transfection; Trypanosoma brucei brucei; Uracil; Uracil-DNA Glycosidase

2002
J-binding protein increases the level and retention of the unusual base J in trypanosome DNA.
    Molecular microbiology, 2002, Volume: 46, Issue:1

    Topics: Animals; Culture Media; DNA-Binding Proteins; DNA, Protozoan; Gene Deletion; Genes, Protozoan; Glucosides; Protozoan Proteins; Trypanosoma brucei brucei; Uracil

2002
[The foundation J. Sanders Ezn. Fonds].
    Tijdschrift Voor Tandheelkunde, 1953, Volume: 60, Issue:2

    Topics: Dentistry; Glucosides; Humans; Uracil

1953
Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases.
    DNA repair, 2004, Feb-03, Volume: 3, Issue:2

    Topics: Animals; Base Pair Mismatch; Cell Nucleus; Cytosine; DNA Damage; DNA Glycosylases; DNA, Protozoan; Gene Expression Regulation, Enzymologic; Glucosides; Oxidative Stress; Trypanosoma brucei brucei; Uracil

2004
Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein.
    Molecular cell, 2005, Feb-04, Volume: 17, Issue:3

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Nucleus; DNA-Binding Proteins; DNA, Protozoan; Gene Expression Regulation, Developmental; Genes, Protozoan; Glucosides; Glycosylation; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Transcription Factors; Transfection; Trypanosoma brucei brucei; Uracil

2005
[Studies on the chemical constituents in herbs of Hemistepta lyrata].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:10

    Topics: 4-Butyrolactone; Asteraceae; Caffeic Acids; Glucosides; Plants, Medicinal; Uracil

2006
Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania.
    Nucleic acids research, 2007, Volume: 35, Issue:7

    Topics: Animals; Chromatography, Agarose; Crithidia fasciculata; DNA, Protozoan; Genome, Protozoan; Glucosides; Immunoblotting; Immunoprecipitation; Leishmania; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Telomere; Trypanosoma cruzi; Uracil

2007
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.
    Nucleic acids research, 2007, Volume: 35, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Dioxygenases; DNA-Binding Proteins; Glucosides; Leishmania; Mixed Function Oxygenases; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; Uracil

2007
JBP2, a SWI2/SNF2-like protein, regulates de novo telomeric DNA glycosylation in bloodstream form Trypanosoma brucei.
    Molecular and biochemical parasitology, 2007, Volume: 156, Issue:1

    Topics: Animals; Antigenic Variation; Blood; DNA-Binding Proteins; DNA, Protozoan; Gene Expression Regulation; Glucosides; Glycosylation; Telomere; Trypanosoma brucei brucei; Uracil

2007
Telomeric co-localization of the modified base J and contingency genes in the protozoan parasite Trypanosoma cruzi.
    Nucleic acids research, 2007, Volume: 35, Issue:19

    Topics: Animals; Cells, Cultured; Genes, Protozoan; Glucosides; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma cruzi; Uracil

2007
Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J.
    Molecular and biochemical parasitology, 2009, Volume: 164, Issue:2

    Topics: Amino Acid Substitution; Animals; DNA-Binding Proteins; DNA, Protozoan; Glucosides; Leishmania; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Protozoan Proteins; Sequence Analysis, DNA; Thymidine; Uracil

2009
JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes.
    Nucleic acids research, 2009, Volume: 37, Issue:5

    Topics: Animals; Cell Line; DNA-Binding Proteins; DNA, Protozoan; Gene Deletion; Genome, Protozoan; Glucosides; Mixed Function Oxygenases; Mutation; Protein Structure, Tertiary; Protozoan Proteins; Trypanosoma brucei brucei; Uracil

2009
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.
    Nucleic acids research, 2010, Volume: 38, Issue:12

    Topics: Animals; Cell Line; DNA-Binding Proteins; DNA, Protozoan; Genome, Protozoan; Glucosides; Histones; Mixed Function Oxygenases; Protozoan Proteins; RNA Polymerase II; Thymidine; Transcription, Genetic; Trypanosoma brucei brucei; Uracil

2010
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.
    Nucleic acids research, 2011, Volume: 39, Issue:13

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Crystallography, X-Ray; DNA; DNA-Binding Proteins; DNA, Bacterial; Glucosides; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Protozoan Proteins; Scattering, Small Angle; Sequence Alignment; Uracil; X-Ray Diffraction

2011
Epigenetic regulation of polymerase II transcription initiation in Trypanosoma cruzi: modulation of nucleosome abundance, histone modification, and polymerase occupancy by O-linked thymine DNA glucosylation.
    Eukaryotic cell, 2011, Volume: 10, Issue:11

    Topics: Acetylation; Chromatin; DNA, Protozoan; Epigenesis, Genetic; Gene Expression Regulation; Glucosides; Glycosylation; Histones; Nucleosomes; Promoter Regions, Genetic; Protozoan Proteins; RNA Polymerase II; Thymine DNA Glycosylase; Transcription, Genetic; Trypanosoma cruzi; Uracil

2011
Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.
    Journal of the American Chemical Society, 2012, Aug-15, Volume: 134, Issue:32

    Topics: Carrier Proteins; Glucosides; Kinetics; Molecular Conformation; Protein Binding; Time Factors; Uracil

2012
[Chemical constituents contained in seeds of Notopterygium franchetii].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7

    Topics: 5-Methoxypsoralen; Apiaceae; Chromatography, Thin Layer; Coumarins; Diosmin; Flavonoids; Furocoumarins; Glucosides; Kynurenic Acid; Magnetic Resonance Spectroscopy; Mannitol; Methoxsalen; Seeds; Sitosterols; Uracil

2012
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.
    Cell, 2012, Aug-31, Volume: 150, Issue:5

    Topics: Gene Knockout Techniques; Glucosides; Leishmania; RNA Polymerase II; RNA, Double-Stranded; Transcription, Genetic; Uracil

2012
Transcription: base J blocks the way.
    Current biology : CB, 2012, Nov-20, Volume: 22, Issue:22

    Topics: Animals; Genome, Protozoan; Glucosides; Leishmania; Molecular Structure; RNA Polymerase II; Transcription, Genetic; Uracil

2012
Identification of the glucosyltransferase that converts hydroxymethyluracil to base J in the trypanosomatid genome.
    The Journal of biological chemistry, 2014, Jul-18, Volume: 289, Issue:29

    Topics: DNA, Protozoan; Epigenesis, Genetic; Gene Knockout Techniques; Genome, Protozoan; Glucosides; Glucosyltransferases; Mutagenesis, Site-Directed; Pentoxyl; Protozoan Proteins; RNA Interference; RNA, Messenger; RNA, Protozoan; Substrate Specificity; Thymine; Trypanosoma brucei brucei; Uracil

2014
Facile enzymatic synthesis of base J-containing oligodeoxyribonucleotides and an analysis of the impact of base J on DNA replication in cells.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Bacteriophage T4; Biocatalysis; DNA Replication; Glucosides; Glucosyltransferases; HEK293 Cells; Humans; Oligodeoxyribonucleotides; Uracil; Viral Proteins

2014
Quantitative mass spectrometry-based analysis of β-D-glucosyl-5-hydroxymethyluracil in genomic DNA of Trypanosoma brucei.
    Journal of the American Society for Mass Spectrometry, 2014, Volume: 25, Issue:10

    Topics: Chromatography, Liquid; DNA, Protozoan; Glucosides; Tandem Mass Spectrometry; Trypanosoma brucei brucei; Uracil

2014
Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei.
    Nucleic acids research, 2014, Volume: 42, Issue:15

    Topics: Cell Line; Gene Expression Regulation; Glucosides; Leishmania major; RNA Polymerase II; RNA, Protozoan; Transcription Termination, Genetic; Trypanosoma brucei brucei; Uracil

2014
Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.
    Nucleic acids research, 2015, Feb-27, Volume: 43, Issue:4

    Topics: DNA-Binding Proteins; Glucosides; Leishmania; Plasmids; Protozoan Proteins; Sequence Analysis, DNA; Uracil

2015
Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei.
    PLoS genetics, 2016, Volume: 12, Issue:1

    Topics: Chromatin; DNA, Protozoan; Glucosides; Histones; RNA Polymerase II; RNA, Small Interfering; Transcription, Genetic; Trypanosoma brucei brucei; Uracil

2016
Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei.
    PLoS genetics, 2016, Volume: 12, Issue:1

    Topics: Chromatin; Gene Expression Regulation; Glucosides; Histones; Promoter Regions, Genetic; RNA Polymerase I; Telomere; Transcription, Genetic; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

2016
Base J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination.
    Molecular microbiology, 2016, Volume: 101, Issue:4

    Topics: Gene Expression Regulation; Glucosides; Leishmania major; Multigene Family; RNA Polymerase II; RNA, Messenger; Transcription, Genetic; Uracil

2016
New Treatments for Type 2 Diabetes Mellitus and Cardiovascular Disease. The Revolution Has Begun.
    Revista espanola de cardiologia (English ed.), 2016, Volume: 69, Issue:11

    Topics: Adamantane; Benzhydryl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide-1 Receptor; Glucosides; Humans; Hypoglycemic Agents; Liraglutide; Peptides; Piperidines; Risk; Sitagliptin Phosphate; Sodium-Glucose Transporter 2 Inhibitors; Uracil

2016
Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania.
    Genome biology, 2017, 01-30, Volume: 18, Issue:1

    Topics: Chromosome Mapping; DNA, Protozoan; Glucosides; Leishmania; Pentoxyl; Uracil

2017
Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.
    Acta crystallographica. Section F, Structural biology communications, 2018, Nov-01, Volume: 74, Issue:Pt 11

    Topics: Animals; Camelids, New World; Crystallography, X-Ray; DNA-Binding Proteins; Glucosides; Models, Molecular; Protein Conformation; Protozoan Proteins; Single-Domain Antibodies; Surface Plasmon Resonance; Uracil

2018
Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes.
    PLoS genetics, 2020, Volume: 16, Issue:2

    Topics: Animals; DNA-Binding Proteins; DNA, Kinetoplast; Genes, Protozoan; Glucosides; Glucosyltransferases; Histones; Leishmania; Mutation; Protozoan Proteins; RNA Interference; RNA Polymerase II; Thymine; Transcription Termination, Genetic; Trypanosoma brucei brucei; Uracil

2020
Highlights from the European society of cardiology congress 2020.
    Journal of thrombosis and thrombolysis, 2021, Volume: 51, Issue:1

    Topics: Atrial Fibrillation; Benzhydryl Compounds; Benzylamines; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Clinical Trials as Topic; Colchicine; Coronary Artery Disease; Europe; Glucosides; Heart Failure; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Societies, Medical; Sodium-Glucose Transporter 2 Inhibitors; Tubulin Modulators; Uracil

2021
Investigation of the effect of Acai berry on the pharmacokinetics of Atorvastatin, Alogliptin and Empagliflozin: a herb-drug interaction study.
    The Journal of pharmacy and pharmacology, 2022, Aug-19, Volume: 74, Issue:8

    Topics: Animals; Atorvastatin; Benzhydryl Compounds; Euterpe; Glucosides; Herb-Drug Interactions; Piperidines; Rats; Rats, Sprague-Dawley; Uracil

2022