uracil and doxifluridine

uracil has been researched along with doxifluridine in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (12.96)	18.7374
1990's	20 (37.04)	18.2507
2000's	19 (35.19)	29.6817
2010's	8 (14.81)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fujimaki, M; Kurokawa, M; Kuroki, Y; Ochiai, H; Okamoto, M; Tazawa, K; Yamashita, I	1
Adachi, S; Akaza, H; Ishitsuka, H; Kanazawa, K; Miwa, M; Nitta, K; Sekiguchi, F; Tokita, H	1
Imai, S; Morimoto, H; Nio, Y; Shiraishi, T; Tobe, T; Tseng, CC; Tsubono, M	1
Arima, S; Fukamura, T; Haruta, J; Hashimoto, M; Jyozaki, H; Okamoto, K; Shimura, H; Umeno, T	1
Kawada, S; Kondo, H; Ootani, I; Sato, T; Shibata, T; Suzuki, H	1
Ando, J; Kosaka, A; Sumiyoshi, K	1
Fujita, F; Fujita, M; Hirai, T; Taguchi, T	1
Fujimoto, K; Ishitsuka, H; Matsuura, N; Miwa, M; Ninomiya, Y; Ryu, M	1
Eda, H; Fujimoto, K; Fukuda, H; Ishitsuka, H; Miwa, M	1
Aubert, C; Cano, JP; Coassolo, P; Rigault, JP; Sommadossi, JP	1
Kimura, K; Suga, S	1
Fujii, S; Shirasaka, T	1
Fujioka, A; Nakano, K; Okabe, H; Saito, H; Takeda, S; Toko, T; Unemi, N	1
Aida, I; Kasuga, Y; Ohwada, M; Sato, I; Suzuki, M; Tamura, T	1
Fukushima, S; Hamada, A; Kawaguchi, T; Morinaga, A; Nakano, M; Saneyoshi, M	1
Fukagawa, H; Hirohashi, Y; Iwanaga, A; Iyama, A; Kitahara, K; Miyazaki, K; Mori, M; Sasatomi, E; Tsutsumi, N; Yakushiji, H	1
Kumagai, K; Masuo, K; Nishida, Y; Yasui, A; Yoshitoshi, A	1
Fukushima, S; Hamada, A; Kawaguchi, T; Nakano, M; Saneyoshi, M; Shimizu, S	2
Fukushima, M; Nakano, K; Saito, H; Satake, H; Takechi, T; Takeda, S; Uchida, J; Unemi, N	1
Fujimaki, M; Katuyama, S; Kuroki, Y; Okamoto, M; Sakamoto, T; Tazawa, K; Yamashita, I	1
Hamada, A; Hasegawa, T; Kawaguchi, T; Nakano, M; Shimidzu, S	1
Taguchi, T	1
González Barón, M	1
Hoshino, K; Ikeda, H; Koyama, T; Morishita, Y; Nakamura, M	1
Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K	1
Musha, N; Oka, K; Saito, H; Sando, N; Sasaki, M; Setu, M; Setu, Y; Sunami, E	1
Britten, C; Hammond, L; Hidalgo, M; Rothenberg, ML; Sharma, A; Sharma, S; Siu, L; Villalona-Calero, M; Weiss, GR	1
Hirakawa, Y; Kawaguchi, Y; Kuwata, K; Matsushima, E; Nagayama, S	1
Aiba, K; Horikoshi, N; Saotome, T; Yoshida, N	1
Katayama, A; Mafune, K; Makuuchi, M	1
Higashigawa, M; Kagawa, Y; Kakito, H; Kawasaki, H; Kojima, M; Ohkubo, T; Ooi, A; Sakurai, M	1
Fujioka, A; Fukushima, M; Nakagawa, F; Nukatsuka, M; Ohshimo, H	1
Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K	1
Fujioka, A; Fukushima, M; Kitazato, K; Nakagawa, F; Nukatsuka, M; Ohshimo, H	1
Ito, T; Nakamura, A; Sato, A; Taguchi, S; Tomita, T	1
Azuma, T; Hatada, T; Inoue, Y; Kusunoki, M; Miki, C; Mohri, T; Ojima, E	1
Handa, R; Iijima, S; Kato, T; Kikkawa, N; Kurokawa, E; Naoi, Y; Oshima, S; Tsujie, M; Yamamoto, H	1
Fujitani, K; Hirao, M; Ikenaga, M; Kashiwazaki, M; Masuda, N; Mishima, H; Sawamura, T; Takeda, Y; Takeno, A; Tsujinaka, T	1
Hayakawa, K; Miyake, K; Morimoto, T; Mukaihara, S; Nishino, M	1
Fujioka, A; Fukushima, M; Ikeda, K; Kitazato, K; Nakagawa, F; Ohshimo, H; Okabe, H; Takechi, T	1
Ikeda, S; Ishibashi, N; Matono, K; Mizobe, T; Ogata, Y; Ogo, S; Ohkita, A; Ozasa, H; Sasatomi, T; Shirouzu, K	1
Hamada, T; Ichimura, W; Minagawa, N; Mino, K; Naito, H; Orimo, T; Shibazaki, W; Shinohara, T	1
Peters, GJ; Prins, HJ; Temmink, OH; van Gelderop, E	1
Hoshino, S; Maekawa, T; Mikami, K; Sakai, T; Shirakusa, T; Yamashita, Y	1
Huh, JW; Kim, HR	1
Beijnen, JH; Rosing, H; Schellens, JH; Vainchtein, LD	1
Nakayama, T; Noguchi, S	1
Bellot, GL; Koh, D; Tan, WH; Tay, LL; Wang, X	1
Chong, KT; Endoh, K; Fukuoka, M; Miyahara, S; Miyakoshi, H; Nagasawa, H; Nomura, M; Shuto, S; Taguchi, J; Takao, Y; Ueno, H; Wakasa, T; Yano, W; Yokogawa, T	1
Hwang, SH; Kim, SG	1
Doki, Y; Fujita, J; Fujitani, K; Fujiwara, Y; Hirao, M; Imamura, H; Kimura, Y; Moon, JH; Mori, M; Takiguchi, S; Tamura, S; Yano, M	1
Chionh, F; Lau, D; Price, T; Tebbutt, N; Yeung, Y	1

Reviews

9 review(s) available for uracil and doxifluridine

Article	Year
[Gastrointestinal cancer and oral anticancer agents]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Drug Combinations; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	1999
[Oral fluoropyrimidines in oncology]. Anales de la Real Academia Nacional de Medicina, 1998, Volume: 115, Issue:3 Topics: Administration, Oral; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Female; Floxuridine; Fluorouracil; Humans; Leucovorin; Male; Neoplasm Recurrence, Local; Neoplasms; Tegafur; Time Factors; Uracil	1998
New anticancer agents. Cancer chemotherapy and biological response modifiers, 1999, Volume: 18 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cyclin-Dependent Kinases; DNA; Floxuridine; Humans; Microtubules; Organoplatinum Compounds; Signal Transduction; Thymidylate Synthase; Uracil	1999
[Oral cancer chemotherapy in the clinic]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:11 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Floxuridine; Hematologic Neoplasms; Humans; Melphalan; Quality of Life; Tamoxifen; Tegafur; Uracil	2000
Adrenalectomy for solitary adrenal metastasis from colorectal carcinoma. Japanese journal of clinical oncology, 2000, Volume: 30, Issue:9 Topics: Adrenal Gland Neoplasms; Adrenalectomy; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Floxuridine; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Pneumonectomy; Rectal Neoplasms; Tegafur; Uracil	2000
[Chemotherapy of gastric cancer--a review of clinical trials in Japan]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Drug Combinations; Floxuridine; Humans; Japan; Methotrexate; Mitomycin; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil	2002
[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Humans; Lymphatic Metastasis; Middle Aged; Radiotherapy, Adjuvant; Tegafur; Uracil	2004
Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan. The oncologist, 2010, Volume: 15, Issue:1 Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Japan; Methotrexate; Oxonic Acid; Tegafur; Uracil	2010
Oral versus intravenous fluoropyrimidines for colorectal cancer. The Cochrane database of systematic reviews, 2017, Jul-28, Volume: 7 Topics: Administration, Oral; Adult; Antineoplastic Agents; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Floxuridine; Fluorouracil; Humans; Injections, Intravenous; Irinotecan; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Palliative Care; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Tegafur; Uracil	2017

Trials

2 trial(s) available for uracil and doxifluridine

Article	Year
[5-FU concentrations in the blood and tumor tissue after 5'-DFUR or UFT administration in the patients with uterine cervical cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:2 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Fluorouracil; Humans; Lymph Nodes; Middle Aged; Tegafur; Uracil; Uterine Cervical Neoplasms	1995
Randomized Controlled Trial of Adjuvant Chemotherapy with Fluoropyrimidines Anticancer research, 2017, Volume: 37, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Stomach Neoplasms; Survival Analysis; Tegafur; Uracil	2017

Other Studies

43 other study(ies) available for uracil and doxifluridine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
[Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:8 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms; Mice; Mice, Inbred BALB C; Tegafur; Uracil	1991
[Comparative studies on the antitumor activity of fluorinated pyrimidine derivatives against human bladder, cervical and ovarian cancer xenografts in nude mice]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:10 Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Fluorouracil; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Tegafur; Uracil; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	1991
[Chemotherapy with fluoropyrimidines for MOPC-104E plasmacytoma transplanted in mice with CCl4 induced chronic liver dysfunction]. Nihon Gan Chiryo Gakkai shi, 1990, Mar-20, Volume: 25, Issue:3 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Floxuridine; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Plasmacytoma; Tegafur; Uracil	1990
[Study of tissue drug concentration of fluorinated pyrimidine anticancer drugs--comparison of 5'DFUR and UFT]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:9 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colon; Colonic Neoplasms; Drug Administration Schedule; Floxuridine; Humans; Lymph Nodes; Tegafur; Uracil	1990
[Two cases of obstructive jaundice due to extrahepatic carcinoma of the bile duct with marked response to daily oral administration of etoposide]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:12 Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cholestasis, Extrahepatic; Common Bile Duct Neoplasms; Etoposide; Female; Floxuridine; Humans; Male; Middle Aged; Picibanil; Remission Induction; Tegafur; Uracil	1990
[The serum and tissue concentration of FT-207, 5'-DFUR and 5-FU in patients with breast cancer by preoperative administration of UFT and 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Floxuridine; Fluorouracil; Humans; Lymph Nodes; Preoperative Care; Tegafur; Tissue Distribution; Uracil	1989
[Evaluation by multiple regression analysis of factors influencing the chemosensitivity of human tumors xenografted into nude mice]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colony-Forming Units Assay; Doxorubicin; Floxuridine; Humans; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Regression Analysis; Tegafur; Tumor Stem Cell Assay; Uracil	1987
[Antitumor activity and toxicity to the immune system and intestine, of the fluorinated pyrimidines FUra, 5'-DFUR, tegafur and UFT]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:5 Topics: Animals; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bone Marrow; Female; Floxuridine; Intestines; Leukopenia; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Spleen; Tegafur; Thymus Gland; Uracil	1988
[Comparative studies on the antitumor activity of the fluorinated pyrimidines 5'-DFUR, tegafur, UFT and FUra on various murine tumors]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorouracil; Leukemia P388; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma 180; Tegafur; Uracil	1988
Quantitative analysis of 5-fluorouracil and 5,6-dihydrofluorouracil in plasma by gas chromatography mass spectrometry. Biomedical mass spectrometry, 1982, Volume: 9, Issue:8 Topics: Chromatography, High Pressure Liquid; Floxuridine; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Time Factors; Uracil	1982
[Pharmacological and pharmacodynamic aspects of cancer chemotherapy, with special reference to 5-fluorouracil and its derivatives]. Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Floxuridine; Fluorouracil; Humans; Kinetics; Neoplasms; Tegafur; Uracil	1982
[Development of fluoropyrimidine derivatives]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11 Topics: Animals; DNA Replication; Floxuridine; Fluorouracil; Mice; Phosphorylation; Pyrimidine Nucleotides; Rats; Sarcoma, Experimental; Tegafur; Uracil	1984
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--growth-inhibitory activity of combination against human tumor xenograft]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:13 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Floxuridine; Humans; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Tegafur; Transplantation, Heterologous; Uracil	1995
Differential effects of acyclothymidine, a potent pyrimidine nucleoside phosphorylase inhibitor, on the pharmacokinetics of doxifluridine in rabbits via oral administration. Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:12 Topics: Administration, Oral; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Interactions; Floxuridine; Fluorouracil; Male; Pentosyltransferases; Pyrimidine Phosphorylases; Rabbits; Uracil	1993
[A comparative study on the serum and tissue 5-FU concentrations in patients with hepatocellular carcinoma after preoperative oral administration of UFT and 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:5 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil	1994
The significance of preoperative chemotherapy for early gastric carcinoma. Surgery today, 1993, Volume: 23, Issue:10 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Prognosis; Stomach Neoplasms; Tegafur; Uracil	1993
Modulation of the pharmacokinetics of 5'-deoxy-5-fluorouridine and 5-fluorouracil in rats by oral co-administration of acyclothymidine. Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:5 Topics: Administration, Oral; Animals; Antineoplastic Agents; Drug Interactions; Enzyme Inhibitors; Floxuridine; Fluorouracil; Intestines; Liver; Male; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Uracil	1996
Acyclothymidine alleviates intestinal toxicity of 5'-deoxy-5-fluorouridine without loss of antitumor activity in mice. Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:10 Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Lewis Lung; Drug Synergism; Enzyme Inhibitors; Floxuridine; Intestines; Isomerism; Mice; Thymidine Phosphorylase; Uracil	1996
[Antimetastatic effects of UFT on murine liver metastasis model using L5178YHM lymphoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:14 Topics: Animals; Body Weight; Drug Combinations; Floxuridine; Leukemia L5178; Liver Neoplasms; Male; Mice; Tegafur; Uracil	1996
Inhibitory effects of fluorinated pyrimidines, 5'-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose. Clinical & experimental metastasis, 1997, Volume: 15, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Female; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tegafur; Uracil	1997
Inhibition of 5'-deoxy-5-fluorouridine phosphorolysis by acyclothymidine in tumor cell homogenates. Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:8 Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Floxuridine; Humans; Kinetics; Mice; Mice, Inbred C57BL; Thymidine Phosphorylase; Tumor Cells, Cultured; Uracil	1997
[Effective chemo-endocrine combination therapy for obstructive-jaundice caused by multiple liver metastasis of recurrent breast cancer--a case report]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:7 Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cholestasis; Cyclophosphamide; Doxorubicin; Drainage; Female; Floxuridine; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Mastectomy, Radical; Medroxyprogesterone Acetate; Tamoxifen; Tegafur; Toremifene; Uracil	1999
UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:8 Topics: 4-Butyrolactone; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cell Division; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Hydroxybutyrates; Kidney Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neovascularization, Pathologic; Tegafur; Tumor Cells, Cultured; Uracil	1999
[Long-term complete response in a case of unresectable rectal cancer following chemoradiation]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:1 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Tegafur; Uracil	2000
[Comparison of pharmacokinetics of 5-FU and alpha-fluoro-beta-alanine, a metabolite of 5-FU, in plasma after administration of UFT, tegafur, 5-FU or doxifluridine to rats]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:6 Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; beta-Alanine; Floxuridine; Fluorouracil; Male; Rats; Rats, Sprague-Dawley; Tegafur; Uracil	2000
Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine. Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Combinations; Floxuridine; Fluorouracil; Intestinal Mucosa; Leukemia L1210; Male; Mice; Tegafur; Uracil	2001
[Antimetastatic and antitumor effects of fluoropyrimidines alone and combined with taxanes in a murine model of breast cancer metastatic to the lung]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:1 Topics: Aminoacridines; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Disease Models, Animal; Drug Combinations; Female; Floxuridine; Humans; Lung Neoplasms; Mice; Mice, Inbred ICR; Mice, SCID; Neoplasm Transplantation; Taxoids; Tegafur; Uracil	2002
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. Angiogenesis, 2001, Volume: 4, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carcinoma, Renal Cell; Chemotaxis; Colonic Neoplasms; DNA Replication; Drug Combinations; Endothelial Growth Factors; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Floxuridine; Fluorouracil; Humans; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Lung Neoplasms; Lymphokines; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Neoplasm Proteins; Neovascularization, Pathologic; Prodrugs; Prostheses and Implants; Recombinant Proteins; Sodium Oxybate; Stomach Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xenograft Model Antitumor Assays	2001
[The antitumor activity of DPD inhibitory-fluoropyrimidine (DIF) and non-DIF alone or in combination with paclitaxel against orthotopically implanted human breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:5 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Floxuridine; Humans; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Oxidoreductases; Paclitaxel; Pyrimidines; Tegafur; Uracil	2002
[A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:10 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Rectal Neoplasms; Tegafur; Uracil	2002
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Rectal Neoplasms; Tegafur; Uracil	2003
Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer. Academic radiology, 2005, Volume: 12, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chi-Square Distribution; Colonic Neoplasms; Fatty Liver; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Retrospective Studies; Tegafur; Tomography, X-Ray Computed; Uracil	2005
Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts. Oncology reports, 2005, Volume: 14, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Line, Tumor; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Floxuridine; Fluorouracil; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Orotate Phosphoribosyltransferase; Oxonic Acid; Pyridines; Tegafur; Thymidine Phosphorylase; Treatment Outcome; Uracil; Xenograft Model Antitumor Assays	2005
The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:5 Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Floxuridine; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Period; Retrospective Studies; Survival Rate; Tegafur; Uracil	2006
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combinations; Floxuridine; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Neoplasm Staging; Picibanil; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil	2005
The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells. British journal of cancer, 2007, Jan-15, Volume: 96, Issue:1 Topics: Administration, Oral; Animals; Apoptosis; Capecitabine; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Deoxycytidine; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Floxuridine; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Pyrrolidines; Sensitivity and Specificity; Thymidine Phosphorylase; Thymine; Treatment Outcome; Trifluridine; Tumor Cells, Cultured; Uracil; Xenograft Model Antitumor Assays	2007
Immunochemotherapy with PSK and fluoropyrimidines improves long-term prognosis for curatively resected colorectal cancer. Cancer biotherapy & radiopharmaceuticals, 2008, Volume: 23, Issue:4 Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Immunotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Proportional Hazards Models; Proteoglycans; Retrospective Studies; Tegafur; Uracil	2008
Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0? Journal of surgical oncology, 2009, Oct-01, Volume: 100, Issue:5 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Floxuridine; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms; Retrospective Studies; Tegafur; Uracil	2009
A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma. Biomedical chromatography : BMC, 2010, Volume: 24, Issue:4 Topics: 1-Propanol; Acetonitriles; Antimetabolites, Antineoplastic; Capecitabine; Chemical Precipitation; Chromatography, High Pressure Liquid; Deoxycytidine; Drug Stability; Floxuridine; Fluorouracil; Furans; Humans; Linear Models; Pyrimidines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Trichloroacetic Acid; Uracil; Vidarabine	2010
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients. Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:3 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Down-Regulation; Doxorubicin; Etoposide; Floxuridine; Fluorescent Antibody Technique; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Irinotecan; Metaphase; Paclitaxel; Polymerase Chain Reaction; Predictive Value of Tests; Protein Array Analysis; Reproducibility of Results; Tegafur; Tissue Array Analysis; Tumor Cells, Cultured; Up-Regulation; Uracil	2012
Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors. Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7 Topics: Antineoplastic Agents; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Drug Synergism; Floxuridine; HeLa Cells; Humans; Models, Molecular; Protein Conformation; Pyrophosphatases; Pyrrolidines; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; Thymidylate Synthase; Uracil	2012
The association between the duration of fluoropyrimidine-based adjuvant chemotherapy and survival in stage II or III gastric cancer. World journal of surgical oncology, 2016, Apr-02, Volume: 14 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Female; Floxuridine; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Prognosis; Retrospective Studies; Stomach Neoplasms; Survival Rate; Tegafur; Time Factors; Uracil	2016

chemdatabank.com