uracil and ce 224,535
uracil has been researched along with ce 224,535 in 2 studies
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Beaulieu, AM; Chang, SP; Dombroski, MA; Duplantier, AJ; Gabel, CA; Jordan, C; Kalgutkar, AS; Kraus, KG; Labasi, JM; Mussari, C; Perregaux, DG; Shepard, R; Subramanyam, C; Taylor, TJ; Trevena, KA; Whitney-Pickett, C; Yoon, K | 1 |
| Bloom, BJ; Gupta, P; Ishaq, S; Mebus, CA; Park, W; Stock, TC; Wang, X; Wei, N | 1 |
Trials
1 trial(s) available for uracil and ce 224,535
| Article | Year |
|---|---|
Efficacy and safety of CE-224,535, an antagonist of P2X7 receptor, in treatment of patients with rheumatoid arthritis inadequately controlled by methotrexate.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Benzamides; Double-Blind Method; Female; Humans; Male; Middle Aged; Placebo Effect; Purinergic P2X Receptor Antagonists; Uracil; Young Adult | 2012 |
Other Studies
1 other study(ies) available for uracil and ce 224,535
| Article | Year |
|---|---|
Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535.
Topics: Administration, Oral; Animals; Antirheumatic Agents; Benzamides; Drug Discovery; Humans; Inhibitory Concentration 50; Molecular Structure; Protein Binding; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2X7; Structure-Activity Relationship; Uracil | 2011 |