up 269-6 has been researched along with l 158809 in 4 studies
| Studies (up 269-6) | Trials (up 269-6) | Recent Studies (post-2010) (up 269-6) | Studies (l 158809) | Trials (l 158809) | Recent Studies (post-2010) (l 158809) |
|---|---|---|---|---|---|
| 15 | 4 | 0 | 137 | 0 | 7 |
| Protein | Taxonomy | up 269-6 (IC50) | l 158809 (IC50) |
|---|---|---|---|
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0021 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0012 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.0015 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.0003 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0021 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.0002 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR | 1 |
| Giridhar, R; Murumkar, P; Naik, P; Yadav, MR | 1 |
| Caussade, F; Cazes, M; Cloarec, A; Delchambre, C; Versigny, A; Virone-Oddos, A | 1 |
| Cazes, M; Cloarec, A; Provost, D; Versigny, A | 1 |
2 review(s) available for up 269-6 and l 158809
| Article | Year |
|---|---|
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship | 1996 |
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan | 2010 |
2 other study(ies) available for up 269-6 and l 158809
| Article | Year |
|---|---|
In vitro pharmacological characterization of UP 269-6, a novel nonpeptide angiotensin II receptor antagonist.
Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding, Competitive; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Pyrimidines; Radioligand Assay; Rats; Tetrazoles | 1995 |
In vivo pharmacological characterization of UP 269-6, a novel nonpeptide angiotensin II receptor antagonist.
Topics: Administration, Oral; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dogs; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Injections, Intravenous; Losartan; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity; Tetrazoles; Vasoconstrictor Agents | 1995 |