up 269-6 and enalapril
up 269-6 has been researched along with enalapril in 2 studies
Compound Research Comparison
| Studies (up 269-6) | Trials (up 269-6) | Recent Studies (post-2010) (up 269-6) | Studies (enalapril) | Trials (enalapril) | Recent Studies (post-2010) (enalapril) |
|---|---|---|---|---|---|
| 15 | 4 | 0 | 6,311 | 1,924 | 859 |
Protein Interaction Comparison
| Protein | Taxonomy | up 269-6 (IC50) | enalapril (IC50) |
|---|---|---|---|
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.3536 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 2.7083 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 1.2 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.14 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.14 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Brunner, HR; Hagmann, M; Hiesse-Provost, O; Inglessis, N; Insuasty, J; Ménard, J; Nussberger, J; Reid, J | 1 |
| Brunner, HR; Insuasty, J; MacFadyen, RJ; McIntyre, M; Menard, J; Meredith, PA; Reid, JL | 1 |
Trials
2 trial(s) available for up 269-6 and enalapril
| Article | Year |
|---|---|
Comparison of the angiotensin II antagonist UP269-6 with the angiotensin converting enzyme inhibitor enalapril in normotensive volunteers challenged with angiotensin I.
Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Humans; Male; Plethysmography; Pyrimidines; Renin; Tetrazoles | 1995 |
Comparison of the oral angiotensin II receptor antagonist UP 269-6 or enalapril 20 mg on blood pressure and neurohormonal effects in salt-deplete man.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Enalapril; Heart Rate; Humans; Male; Pyrimidines; Radioimmunoassay; Renin; Tetrazoles | 1995 |