Page last updated: 2024-09-03

up 269-6 and enalapril

up 269-6 has been researched along with enalapril in 2 studies

Compound Research Comparison

Studies (up 269-6)	Trials (up 269-6)	Recent Studies (post-2010) (up 269-6)	Studies (enalapril)	Trials (enalapril)	Recent Studies (post-2010) (enalapril)
15	4	0	6,311	1,924	859

Protein Interaction Comparison

Protein	Taxonomy	enalapril (IC50)
Angiotensin-converting enzyme	Homo sapiens (human)	0.3536
Angiotensin-converting enzyme	Oryctolagus cuniculus (rabbit)	2.7083
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	1.2
Angiotensin-converting enzyme	Rattus norvegicus (Norway rat)	0.14
Angiotensin-converting enzyme 2	Homo sapiens (human)	0.14

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brunner, HR; Hagmann, M; Hiesse-Provost, O; Inglessis, N; Insuasty, J; Ménard, J; Nussberger, J; Reid, J	1
Brunner, HR; Insuasty, J; MacFadyen, RJ; McIntyre, M; Menard, J; Meredith, PA; Reid, JL	1

Trials

2 trial(s) available for up 269-6 and enalapril

Article	Year
Comparison of the angiotensin II antagonist UP269-6 with the angiotensin converting enzyme inhibitor enalapril in normotensive volunteers challenged with angiotensin I. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6 Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Humans; Male; Plethysmography; Pyrimidines; Renin; Tetrazoles	1995
Comparison of the oral angiotensin II receptor antagonist UP 269-6 or enalapril 20 mg on blood pressure and neurohormonal effects in salt-deplete man. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6 Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Enalapril; Heart Rate; Humans; Male; Pyrimidines; Radioimmunoassay; Renin; Tetrazoles	1995

Article

Year

Comparison of the angiotensin II antagonist UP269-6 with the angiotensin converting enzyme inhibitor enalapril in normotensive volunteers challenged with angiotensin I.

Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6

Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Humans; Male; Plethysmography; Pyrimidines; Renin; Tetrazoles

1995

Comparison of the oral angiotensin II receptor antagonist UP 269-6 or enalapril 20 mg on blood pressure and neurohormonal effects in salt-deplete man.

Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6

Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Enalapril; Heart Rate; Humans; Male; Pyrimidines; Radioimmunoassay; Renin; Tetrazoles

1995