Page last updated: 2024-08-17

unithiol and penicillamine

unithiol has been researched along with penicillamine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199015 (41.67)18.7374
1990's9 (25.00)18.2507
2000's5 (13.89)29.6817
2010's5 (13.89)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Lubianova, IP1
Jones, MM; Pratt, TH1
Malyshev, IuI1
Funakoshi, T; Kiyozumi, M; Kojima, S; Shimada, H; Takahashi, Y1
Benov, LC; Monovich, OH; Ribarov, SR1
Chisolm, JJ1
Kiyozumi, M; Kojima, S; Tagawa, Y; Takahashi, Y1
Dobronravov, AV1
Benchev, IC; Benov, LC; Monovich, OH1
Fichtl, B; Forth, W; Kreppel, H; Reichl, FX1
Basinger, MA; Forti, RL; Gibbs, SJ; Jones, MM; Mitchell, WM1
Walshe, JM1
Belcheva, A; Ivanov, N; Kalitsin, I; Mangŭrova, M; Zheliazkov, D1
Micheva, M; Stoĭchev, Ts1
Planas-Bohne, F1
Aposhian, HV1
Banner, W; Berlin, M; Clarkson, TW; Lund, ME1
Halstead, BW; Williams, DR1
Al-Damluji, SF; Amin-Zaki, L; Clarkson, TW; Cox, C; Greenwood, MR; Magos, L; Majeed, MA1
Botvinnik, VS; Lekar', PG; Makarova, VA1
Aaseth, J; Wannag, A1
Aposhian, HV; Maiorino, RM; Xu, ZF1
Aposhian, HV; Fernando, Q; Gandolfi, AJ; Keith, RL; Setiarahardjo, I1
Shafer, TJ1
Binns, H; Shannon, M; Woolf, A1
Henkel, R; Schill, WB; Wroblewski, N1
Johri, S; Sharma, P; Shrivastava, S; Shukla, S1
Hjelmhaug, J; Lobner, D; Rush, T1
Ariño, C; Chekmeneva, E; Díaz-Cruz, JM; Esteban, M1
Chen, L; Fang, F; Li, XF; Liu, Y; Xu, SQ; Zhu, HY1
Aaseth, J; Andersen, O; Cao, Y; Skaug, MA2
Dalkiran, T; Davutoğlu, M; Dilber, C; Güngör, G; Güngör, O; Işikay, S; Kirik, S; Özkaya, AK1
Chiu, YJ; Han, YS; Han, YZ; Rao, R; Shu, S1
Chen, DB; Feng, L; Li, XH; Liang, XL; Pu, XY; Qin, HL; Wu, C; Xiao, X; Zhou, X1
Xiao, L; Yang, W; Zhang, J1

Reviews

4 review(s) available for unithiol and penicillamine

ArticleYear
Therapeutic chelating agents.
    Journal of chemical education, 1976, Volume: 53, Issue:6

    Topics: Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Metallothionein; Metals; Penicillamine; Poisoning; Unithiol

1976
Chelating agents in medicine.
    Journal of toxicology. Clinical toxicology, 1982, Volume: 19, Issue:10

    Topics: Aluminum; Cadmium; Chelating Agents; Chromium; Copper; Deferoxamine; Dimercaprol; Edetic Acid; Environmental Pollutants; Humans; Iron; Mercury; Metals; Molybdenum; Penicillamine; Plutonium; Unithiol

1982
Chelation therapy in intoxications with mercury, lead and copper.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 31

    Topics: Administration, Oral; Animals; Chelating Agents; Chelation Therapy; Copper; Drug Therapy, Combination; Evidence-Based Medicine; Free Radical Scavengers; Humans; Infusions, Parenteral; Lead Poisoning; Mercury Poisoning; Penicillamine; Succimer; Trientine; Unithiol

2015
Chelation in metal intoxication--Principles and paradigms.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 31

    Topics: Administration, Oral; Antidotes; Benzoates; Chelating Agents; Deferasirox; Deferiprone; Deferoxamine; Heavy Metal Poisoning; Humans; Penicillamine; Poisoning; Pyridones; Succimer; Triazoles; Trientine; Unithiol

2015

Trials

2 trial(s) available for unithiol and penicillamine

ArticleYear
Tests of efficacy of antidotes for removal of methylmercury in human poisoning during the Iraq outbreak.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1

    Topics: Adolescent; Adult; Antidotes; Chelating Agents; Child; Child, Preschool; Female; Half-Life; Hematocrit; Humans; Infant; Iraq; Male; Mercury; Methylmercury Compounds; Middle Aged; Penicillamine; Resins, Synthetic; Unithiol

1981
A study of susceptibility-weighted imaging in patients with Wilson disease during the treatment of metal chelator.
    Journal of neurology, 2020, Volume: 267, Issue:6

    Topics: Adolescent; Adult; Chelating Agents; Copper; Female; Globus Pallidus; Hepatolenticular Degeneration; Humans; Magnetic Resonance Imaging; Male; Outcome Assessment, Health Care; Penicillamine; Substantia Nigra; Unithiol; Young Adult

2020

Other Studies

30 other study(ies) available for unithiol and penicillamine

ArticleYear
[Pharmacodynamic characteristics of dithiol compounds and D-penicillamine in microsaturnism].
    Vrachebnoe delo, 1979, Issue:11

    Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lead Poisoning; Male; Middle Aged; Occupational Diseases; Penicillamine; Succimer; Sulfhydryl Compounds; Unithiol

1979
[Hepato-cerebral dystrophy in children].
    Pediatriia, 1975, Issue:12

    Topics: Adolescent; Child; Female; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Unithiol

1975
Characterization of gold in urine and bile following administration of gold sodium thiomalate with chelating agents to rats.
    Toxicology, 1992, Volume: 74, Issue:1

    Topics: Animals; Bile; Chelating Agents; Chromatography; Cysteine; Electrophoresis; Gold; Gold Sodium Thiomalate; Injections, Intravenous; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol

1992
Study of activated oxygen production by some thiols using chemiluminescence.
    General physiology and biophysics, 1992, Volume: 11, Issue:2

    Topics: Cysteine; Glutathione; Kinetics; Lipid Peroxidation; Luminescent Measurements; Malondialdehyde; Oxidation-Reduction; Penicillamine; Succimer; Sulfhydryl Compounds; Superoxides; Unithiol

1992
BAL, EDTA, DMSA and DMPS in the treatment of lead poisoning in children.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:4

    Topics: Administration, Oral; Beverages; Chelation Therapy; Child; Child, Preschool; Dimercaprol; Edetic Acid; Female; Housing; Humans; Infant; Lead; Lead Poisoning; Male; Penicillamine; Succimer; Unithiol

1992
Protective effects of chelating agents against renal toxicity of gold sodium thiomalate in rats.
    Archives of toxicology, 1991, Volume: 65, Issue:7

    Topics: Animals; Chelating Agents; Cysteine; Glycosuria; Gold Sodium Thiomalate; Kidney Diseases; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol

1991
[The combined therapy and dispensary care of children poisoned by mercury and its compounds].
    Fel'dsher i akusherka, 1991, Volume: 56, Issue:10

    Topics: Ambulatory Care; Child; Child, Preschool; Combined Modality Therapy; Edetic Acid; Fluid Therapy; Humans; Mercury Poisoning; Penicillamine; Time Factors; Unithiol

1991
Thiol antidotes effect on lipid peroxidation in mercury-poisoned rats.
    Chemico-biological interactions, 1990, Volume: 76, Issue:3

    Topics: Animals; Fluorescent Dyes; Free Radical Scavengers; In Vitro Techniques; Kidney; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Mercury Poisoning; Oxygen; Penicillamine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Unithiol

1990
Lack of effectiveness of D-penicillamine in experimental arsenic poisoning.
    Veterinary and human toxicology, 1989, Volume: 31, Issue:1

    Topics: Animals; Arsenic; Arsenic Poisoning; Dimercaprol; Guinea Pigs; Male; Mice; Penicillamine; Succimer; Tissue Distribution; Unithiol

1989
Antidotes for gold (sodium bis[thiosulfato]gold[I]) intoxication in mice.
    The Journal of rheumatology, 1985, Volume: 12, Issue:2

    Topics: Animals; Antidotes; Evaluation Studies as Topic; Gold; Gold Sodium Thiosulfate; Kidney; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred ICR; Penicillamine; Succimer; Time Factors; Unithiol

1985
Unithiol in Wilson's disease.
    British medical journal (Clinical research ed.), 1985, Mar-02, Volume: 290, Issue:6469

    Topics: Adolescent; Copper; Dimercaprol; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Unithiol

1985
[Organ-dependent sulfhydryl group reduction in acute mercury poisoning and the effects of mono- and dithiol antidotes and the protein hydrolysate Khidroprot].
    Eksperimentalna meditsina i morfologiia, 1985, Volume: 24, Issue:2

    Topics: Acute Disease; Animals; Antidotes; Dimercaprol; Drug Evaluation, Preclinical; Male; Mercury Poisoning; Penicillamine; Protein Hydrolysates; Rats; Sulfhydryl Compounds; Tissue Distribution; Unithiol

1985
[Effect of thiol compounds on aniline toxicity and aniline metabolism].
    Eksperimentalna meditsina i morfologiia, 1980, Volume: 19, Issue:1

    Topics: Aniline Compounds; Aniline Hydroxylase; Animals; Carbonates; Ditiocarb; Drug Synergism; Enzyme Activation; Liver; Male; Methemoglobin; Penicillamine; Rats; Sulfhydryl Compounds; Thiones; Time Factors; Unithiol

1980
The influence of chelating agents on the distribution and biotransformation of methylmercuric chloride in rats.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2

    Topics: Animals; Biotransformation; Chelating Agents; Male; Methylmercury Compounds; Penicillamine; Rats; Succimer; Tissue Distribution; Unithiol

1981
Biological chelation: 2,3-dimercapto-propanesulfonic acid and meso-dimercaptosuccinic acid.
    Advances in enzyme regulation, 1982, Volume: 20

    Topics: Animals; Arsenic Poisoning; Arsenites; Cadmium Poisoning; Chelating Agents; Dimercaprol; Lethal Dose 50; Male; Mice; Penicillamine; Sodium Compounds; Succimer; Sulfhydryl Compounds; Unithiol

1982
Treatment of acute methylmercury ingestion by hemodialysis with N-acetylcysteine (Mucomyst) infusion and 2,3-dimercaptopropane sulfonate.
    Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Adult; Benztropine; Haloperidol; Humans; Kinetics; Male; Mercury; Methylmercury Compounds; Penicillamine; Renal Dialysis; Suicide, Attempted; Unithiol

1984
[Treatment of hepatocerebral dystrophy (Wilson-Westphal-Konovalov's disease)].
    Sovetskaia meditsina, 1981, Issue:6

    Topics: Amino Acids; Ceruloplasmin; Diet Therapy; Drug Evaluation; Drug Therapy, Combination; Hepatolenticular Degeneration; Humans; Penicillamine; Pyridoxine; Unithiol

1981
The effect of immediate and delayed treatment with 2,3-dimercaptopropane-1-sulphonate on the distribution and toxicity of inorganic mercury in mice and in foetal and adult rats.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:2

    Topics: Animals; Brain; Chelating Agents; Dimercaprol; Extraembryonic Membranes; Feces; Female; Fetus; Kidney; Liver; Maternal-Fetal Exchange; Mercury; Mercury Poisoning; Mice; Penicillamine; Placenta; Pregnancy; Rats; Time Factors; Unithiol

1980
Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Adult; Captopril; Chelating Agents; Chromatography, Thin Layer; Cysteine; Disulfides; Dithiothreitol; Humans; Male; Penicillamine; Protein Binding; Serum Albumin; Unithiol

1996
Utilization of renal slices to evaluate the efficacy of chelating agents for removing mercury from the kidney.
    Toxicology, 1997, Jan-15, Volume: 116, Issue:1-3

    Topics: Animals; Antidotes; Chelating Agents; Dithiothreitol; Drug Evaluation, Preclinical; Edetic Acid; Evaluation Studies as Topic; Glutathione; Kidney; Male; Mercuric Chloride; Mercury; Penicillamine; Rabbits; Succimer; Thioctic Acid; Unithiol

1997
Effects of Cd2+, Pb2+ and CH3Hg+ on high voltage-activated calcium currents in pheochromocytoma (PC12) cells: potency, reversibility, interactions with extracellular Ca2+ and mechanisms of block.
    Toxicology letters, 1998, Nov-12, Volume: 99, Issue:3

    Topics: Animals; Cadmium; Calcium; Calcium Channels; Chelating Agents; Extracellular Space; Ion Channel Gating; Lead; Methylmercury Compounds; Patch-Clamp Techniques; PC12 Cells; Penicillamine; Rats; Unithiol

1998
Chelation therapy in children exposed to lead.
    The New England journal of medicine, 2001, Oct-18, Volume: 345, Issue:16

    Topics: Chelating Agents; Chelation Therapy; Child; Humans; Lead; Lead Poisoning; Penicillamine; Succimer; Unithiol

2001
Metal chelators change the human sperm motility pattern.
    Fertility and sterility, 2003, Volume: 79 Suppl 3

    Topics: Chelating Agents; Dose-Response Relationship, Drug; Humans; Male; Penicillamine; Prospective Studies; Sperm Motility; Spermatozoa; Succimer; Unithiol

2003
Analysis of time-dependent recovery from beryllium toxicity following chelation therapy and antioxidant supplementation.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:8

    Topics: Animals; Antioxidants; Beryllium; Chelation Therapy; Female; Glutathione; Kidney; Lipid Peroxidation; Liver; Penicillamine; Rats; Rats, Sprague-Dawley; Selenium; Time Factors; Unithiol

2004
Effects of chelators on mercury, iron, and lead neurotoxicity in cortical culture.
    Neurotoxicology, 2009, Volume: 30, Issue:1

    Topics: Animals; Brain Chemistry; Cell Death; Cells, Cultured; Cerebral Cortex; Chelating Agents; Drug Synergism; Edetic Acid; Female; Iron; Lead; Mercuric Chloride; Methylmercury Compounds; Mice; Penicillamine; Pregnancy; Succimer; Thimerosal; Unithiol

2009
Study of the Hg2+ binding with chelation therapy agents by differential pulse voltammetry on rotating Au-disk electrode and electrospray ionization mass-spectrometry.
    Analytica chimica acta, 2009, Oct-19, Volume: 653, Issue:1

    Topics: Chelating Agents; Chelation Therapy; Electrodes; Gold; Least-Squares Analysis; Mercury; Penicillamine; Spectrometry, Mass, Electrospray Ionization; Succimer; Unithiol

2009
Clinical efficacy and safety of chelation treatment with typical penicillamine in cross combination with DMPS repeatedly for Wilson's disease.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2013, Volume: 33, Issue:5

    Topics: Administration, Oral; Adolescent; Chelating Agents; Chelation Therapy; Child; Copper; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Hepatolenticular Degeneration; Humans; Injections, Intravenous; Male; Neutropenia; Partial Thromboplastin Time; Penicillamine; Prothrombin Time; Thrombocytopenia; Time Factors; Treatment Outcome; Unithiol

2013
Acute Mercury Poisoning in a Group of School Children.
    Pediatric emergency care, 2019, Volume: 35, Issue:10

    Topics: Acute Disease; Adolescent; Chelating Agents; Child; Environmental Exposure; Female; Humans; Male; Mercury; Mercury Poisoning; Pediatric Emergency Medicine; Penicillamine; Schools; Turkey; Unithiol

2019
A case report: Co-occurrence of Wilson disease and oculocutaneous albinism in a Chinese patient.
    Medicine, 2018, Volume: 97, Issue:50

    Topics: Albinism, Oculocutaneous; Asian People; Astringents; Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Magnetic Resonance Imaging; Mutation; Penicillamine; Treatment Outcome; Unithiol; Young Adult; Zinc Sulfate

2018
Combined sodium Dimercaptopropanesulfonate and zinc versus D-penicillamine as first-line therapy for neurological Wilson's disease.
    BMC neurology, 2020, Jun-27, Volume: 20, Issue:1

    Topics: Adult; Chelating Agents; Drug Therapy, Combination; Female; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Retrospective Studies; Treatment Outcome; Unithiol; Zinc

2020