unc-0638 and sinefungin

unc-0638 has been researched along with sinefungin* in 1 studies

Other Studies

1 other study(ies) available for unc-0638 and sinefungin

Article	Year
Cycloalkane analogues of sinefungin as EHMT1/2 inhibitors. Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17 A series of cycloalkyl substituted analogues of the natural product sinefungin lacking the amino-acid moiety was designed and synthesized. Two stereoisomers (6-R and 6-S) were separated and their bioactivities examined against EHMT1/2. Of which, compound 14d showed an inhibitory activity against EHMT1/2 (88.9%, IC Topics: Adenosine; Alkanes; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Inhibitory Concentration 50; Structure-Activity Relationship	2017

Article

Year

Cycloalkane analogues of sinefungin as EHMT1/2 inhibitors.

Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

A series of cycloalkyl substituted analogues of the natural product sinefungin lacking the amino-acid moiety was designed and synthesized. Two stereoisomers (6-R and 6-S) were separated and their bioactivities examined against EHMT1/2. Of which, compound 14d showed an inhibitory activity against EHMT1/2 (88.9%, IC

Topics: Adenosine; Alkanes; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Inhibitory Concentration 50; Structure-Activity Relationship

2017