Compounds > umifenovir
Page last updated: 2024-09-03

umifenovir and amantadine

umifenovir has been researched along with amantadine in 7 studies

Compound Research Comparison

Studies
(umifenovir)		Trials
(umifenovir)		Recent Studies (post-2010)
(umifenovir)		Studies
(amantadine)		Trials
(amantadine)		Recent Studies (post-2010) (amantadine)
234231724,110515753

Protein Interaction Comparison

ProteinTaxonomyumifenovir (IC50)amantadine (IC50)
Matrix protein 2Influenza A virus (A/udorn/1972(H3N2))4.7

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Chen, X; Lin, W; Liu, D; Proksch, P; Si, L; Zhang, L; Zhou, D1
Lin, W; Liu, D; Niu, S; Shao, Z; Si, L; Wang, S; Zhang, L; Zhang, Z; Zhou, A; Zhou, D1
Çapan, G; Cihan-Üstündağ, G; Naesens, L; Ozkirimli, E; Persoons, L; Vanderlinden, E; Zopun, M1
Duan, Z; Gu, Q; Li, D; Li, J; Liu, Y; Wang, W; Wu, G; Yang, S; Yu, G; Yu, R; Yu, Y; Zhu, T1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Fediakina, IT; Glushkov, RG; Gus'kova, TA; Leneva, IA1
Li, JF; Shen, JS; Xiong, RS; Zhang, Q; Zhao, QJ1

Reviews

1 review(s) available for umifenovir and amantadine

ArticleYear
[Research progress of anti-influenza virus agents].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:3

    Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Cyclopentanes; Guanidines; Humans; Indoles; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrrolidines; Rimantadine; Structure-Activity Relationship; Viral Matrix Proteins; Zanamivir

2010

Other Studies

6 other study(ies) available for umifenovir and amantadine

ArticleYear
Neoechinulin B and its analogues as potential entry inhibitors of influenza viruses, targeting viral hemagglutinin.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Alkaloids; Animals; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cytopathogenic Effect, Viral; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Viral; Eurotium; HEK293 Cells; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Molecular Structure; Piperazines; Structure-Activity Relationship; Viral Plaque Assay

2015
Spiromastilactones: A new class of influenza virus inhibitors from deep-sea fungus.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Animals; Antiviral Agents; Aquatic Organisms; Benzofurans; Dogs; Dose-Response Relationship, Drug; Influenza A virus; Lactones; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Onygenales; Structure-Activity Relationship

2016
Superior inhibition of influenza virus hemagglutinin-mediated fusion by indole-substituted spirothiazolidinones.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Animals; Antiviral Agents; Dogs; Dose-Response Relationship, Drug; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Hydrogen-Ion Concentration; Indoles; Influenza A Virus, H3N2 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Protein Refolding; Spiro Compounds; Structure-Activity Relationship; Thiazolidines

2020
Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion.
    Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13

    Topics: Acetophenones; Adsorption; Animals; Antiviral Agents; Dogs; Drug Discovery; Drug Resistance, Viral; Female; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A virus; Madin Darby Canine Kidney Cells; Membrane Fusion; Mice; Tissue Distribution; Virus Internalization; Virus Replication

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[Sensitivity of various influenza virus strains to arbidol. Influence of arbidol combination with different antiviral drugs on reproduction of influenza virus A].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:8

    Topics: Amantadine; Animals; Antiviral Agents; Dogs; Drug Therapy, Combination; Embryo, Mammalian; Indoles; Influenza A virus; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Ribavirin; Virus Replication

2005