ulipristal acetate has been researched along with mifepristone in 28 studies
| Studies (ulipristal acetate) | Trials (ulipristal acetate) | Recent Studies (post-2010) (ulipristal acetate) | Studies (mifepristone) | Trials (mifepristone) | Recent Studies (post-2010) (mifepristone) |
|---|---|---|---|---|---|
| 376 | 41 | 347 | 6,536 | 595 | 1,758 |
| Protein | Taxonomy | ulipristal acetate (IC50) | mifepristone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Canis lupus familiaris (dog) | 0.0264 | |
| Bile salt export pump | Homo sapiens (human) | 2.02 | |
| Estrogen receptor | Homo sapiens (human) | 4.311 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.0249 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.0003 | |
| Progesterone receptor | Homo sapiens (human) | 0.1347 | |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.774 | |
| Glucocorticoid receptor | Mus musculus (house mouse) | 0.0022 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 2.0938 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 9.5 | |
| Coagulation factor VII | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Homo sapiens (human) | 0.2988 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 1.5 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4.9 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 0.0016 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.555 | |
| Tissue factor | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0083 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0014 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.0022 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0078 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Mu-type opioid receptor | Homo sapiens (human) | 2.457 | |
| Estrogen receptor beta | Homo sapiens (human) | 1.528 | |
| Glucocorticoid receptor | Sus scrofa (pig) | 0.0153 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 26 (92.86) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Breslin, M; Cidlowski, JA; Cook, CE; Giangrande, P; Mais, DE; McDonnell, DP; Pollio, G; Vedeckis, WV; Wagner, BL; Webster, JC | 1 |
| Sarkar, NN | 1 |
| Bouchard, P | 1 |
| Angiolucci, M; Guerriero, S; Lello, S; Maricosu, G; Marotto, MF; Melis, GB; Orru', MM; Paoletti, AM; Pilloni, M; Piras, B | 1 |
| Martinez, AM; Thomas, MA | 1 |
| Che, Y; Cheng, L; Gülmezoglu, AM | 1 |
| Manyonda, I; Talaulikar, VS | 1 |
| Batur, P | 1 |
| Cheng, L; Gemzell-Danielsson, K; Rabe, T | 1 |
| Driák, D; Sehnal, B; Svandová, I | 1 |
| Bastianelli, C; Benagiano, G; Brosens, I; Farris, M | 1 |
| Ho, PC; Li, HW; Lo, SS | 1 |
| Ho, PC; Li, HW; Liao, SB; Ng, EH; O, WS; Yeung, WS | 1 |
| Chiu, PC; Ho, PC; Huang, VW; Ko, JK; Li, RH; Yeung, WS | 1 |
| Fischer, L; Noethling, C; Schaefer, WR; Yin, Q | 1 |
| Nelson, AL | 1 |
| Najera, DB | 1 |
| Abraham, T; Arian, SE; Bartels, CB; Cayton, KC; Chuong, FS; Holthouser, K; Segars, JH | 1 |
| Centini, G; Kashani, BN; Morelli, SS; Petraglia, F; Weiss, G | 1 |
| Chow, TL; Murji, A; Sobel, ML; Whitaker, L | 1 |
| Che, Y; Chen, K; Cheng, L; Shen, J; Showell, E | 1 |
| Fan, H; Ho, PC; Lee, KF; Li, HWR; Li, TT; Li, YX; Ng, EH; Yeung, WS | 1 |
| Bagchi, IC; Bagchi, MK; Bhurke, A; Gemzell-Danielsson, K; Kannan, A; Lalitkumar, PG; Sitruk-Ware, R; Taylor, RN; Williams, ARW | 1 |
| Belland, L; Leyland, N; Murji, A; Singh, SS; von Riedemann, S | 1 |
| Bouchard, P; Chabbert-Buffet, N; Daraï, E; Kolanska, K | 1 |
| Maduro, MR | 1 |
| Barrera, D; Becerra, RG; Díaz, L; Durand, M; García-Quiroz, J; Larrea, F; Lira-Albarrán, S; Rangel, C; Vega, C | 1 |
| Bosland, MC; Clare, SE; Helenowski, I; Hosseini, O; Khan, SA; Kim, JJ; Lee, O; Patel, P; Schipma, MJ; Shidfar, A; Wang, M; Xuei, X | 1 |
15 review(s) available for ulipristal acetate and mifepristone
| Article | Year |
|---|---|
Current and future medical treatments for menometrorrhagia during the premenopause.
Topics: Adolescent; Adult; Contraceptives, Oral; Endometrial Neoplasms; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Levonorgestrel; Menorrhagia; Metrorrhagia; Mifepristone; Norpregnadienes; Polyps; Premenopause; Progestins; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms | 2011 |
Ulipristal acetate as an emergency contraceptive agent.
Topics: Administration, Oral; Animals; Contraception, Postcoital; Contraceptives, Postcoital; Female; Humans; Levonorgestrel; Mifepristone; Norpregnadienes; Receptors, Progesterone; Time Factors | 2012 |
Interventions for emergency contraception.
Topics: Contraception, Postcoital; Contraceptives, Postcoital; Drug Administration Schedule; Female; Humans; Levonorgestrel; Mifepristone; Norpregnadienes; Randomized Controlled Trials as Topic | 2012 |
Progesterone and progesterone receptor modulators in the management of symptomatic uterine fibroids.
Topics: Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Hyperplasia; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone | 2012 |
Emergency contraception: separating fact from fiction.
Topics: Abortion, Induced; Contraception, Postcoital; Counseling; Crime Victims; Female; Hospitals; Humans; Intrauterine Devices, Copper; Levonorgestrel; Mifepristone; Nonprescription Drugs; Norpregnadienes; Obesity; Practice Patterns, Physicians'; Pregnancy; Pregnancy, Unplanned; Sex Offenses; United States | 2012 |
Selective progesterone receptor modulators: an update.
Topics: Adenomyosis; Animals; Clinical Trials as Topic; Contraception, Postcoital; Contraceptive Agents, Female; Contraceptives, Postcoital; Endometriosis; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone; Uterine Neoplasms | 2014 |
Emergency contraception.
Topics: Contraception, Postcoital; Contraceptive Agents, Female; Contraceptives, Oral, Synthetic; Drug Administration Schedule; Female; Health Knowledge, Attitudes, Practice; Humans; Intrauterine Devices, Copper; Levonorgestrel; Mifepristone; Norpregnadienes; Time Factors | 2014 |
Investigational hormone receptor agonists as ongoing female contraception: a focus on selective progesterone receptor modulators in early clinical development.
Topics: Animals; Contraceptive Agents, Female; Drugs, Investigational; Female; Humans; Mifepristone; Norpregnadienes; Ovulation; Receptors, Progesterone | 2015 |
Emergency contraception: Focus on the facts.
Topics: Contraception; Contraception, Postcoital; Contraceptives, Oral, Hormonal; Cyclooxygenase Inhibitors; Female; Health Services Accessibility; Humans; Intrauterine Devices; Levonorgestrel; Meloxicam; Mifepristone; Norpregnadienes; Ovulation Inhibition; Pregnancy; Thiazines; Thiazoles | 2016 |
An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review.
Topics: Androgens; Aromatase Inhibitors; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Curcumin; Delayed-Action Preparations; Drugs, Chinese Herbal; Estradiol; Estrenes; Estrogen Receptor Antagonists; Evidence-Based Medicine; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Neoadjuvant Therapy; Norpregnadienes; Oximes; Plant Extracts; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tea; Uterine Myomectomy; Uterine Neoplasms; Vitamin D; Vitamins | 2016 |
Role of Medical Management for Uterine Leiomyomas.
Topics: Antifibrinolytic Agents; Aromatase Inhibitors; Cabergoline; Cholecalciferol; Contraceptive Agents, Female; Contraceptives, Oral, Hormonal; Contraceptives, Oral, Synthetic; Danazol; Dopamine Agonists; Ergolines; Estrenes; Estrogen Antagonists; Female; Gestrinone; Gonadotropin-Releasing Hormone; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Patient Care Planning; Selective Estrogen Receptor Modulators; Somatostatin; Tranexamic Acid; Uterine Neoplasms; Vitamins | 2016 |
Selective progesterone receptor modulators (SPRMs) for uterine fibroids.
Topics: Amenorrhea; Antineoplastic Agents, Hormonal; Estrenes; Female; Humans; Leiomyoma; Leuprolide; Menstruation; Mifepristone; Norpregnadienes; Oximes; Pelvic Pain; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms | 2017 |
Interventions for emergency contraception.
Topics: Contraception, Postcoital; Contraceptives, Postcoital; Drug Administration Schedule; Estradiol; Female; Humans; Intrauterine Devices, Copper; Intrauterine Devices, Medicated; Levonorgestrel; Mifepristone; Norpregnadienes; Pregnancy; Pregnancy Rate; Randomized Controlled Trials as Topic; Unsafe Sex | 2017 |
The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids.
Topics: Contraceptive Agents, Female; Disease Management; Estrenes; Female; Forecasting; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Population Growth; Receptors, Progesterone; Steroids; Uterine Neoplasms | 2018 |
Selective progesterone receptor modulators: current applications and perspectives.
Topics: Abortion, Induced; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Pregnancy; Progesterone; Receptors, Progesterone; Uterine Hemorrhage; Uterine Neoplasms | 2018 |
1 trial(s) available for ulipristal acetate and mifepristone
| Article | Year |
|---|---|
A single preovulatory administration of ulipristal acetate affects the decidualization process of the human endometrium during the receptive period of the menstrual cycle.
Topics: Adult; Biomarkers; Biopsy; Decidua; Endometrium; Female; Gene Expression Regulation; Humans; Medroxyprogesterone Acetate; Menstrual Cycle; Mifepristone; Models, Biological; Norpregnadienes; Ovulation; Signal Transduction; Transcription, Genetic | 2018 |
12 other study(ies) available for ulipristal acetate and mifepristone
| Article | Year |
|---|---|
The novel progesterone receptor antagonists RTI 3021-012 and RTI 3021-022 exhibit complex glucocorticoid receptor antagonist activities: implications for the development of dissociated antiprogestins.
Topics: Apoptosis; Cell Line; Estrenes; HeLa Cells; Hormone Antagonists; Humans; Ligands; Mifepristone; Promoter Regions, Genetic; Receptors, Glucocorticoid; Receptors, Progesterone; Transcription, Genetic | 1999 |
The state-of-the-art of emergency contraception with the cutting edge drug.
Topics: Contraception, Postcoital; Contraceptive Agents, Female; Estrenes; Female; Gonanes; Humans; Mifepristone; Norpregnadienes; Oximes; Pregnancy; Receptors, Progesterone | 2011 |
Pharmacokinetic evaluation of ulipristal acetate for uterine leiomyoma treatment.
Topics: Adult; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Female; Hormone Antagonists; Humans; Leiomyoma; Menorrhagia; Mifepristone; Norpregnadienes; Progesterone; Receptors, Progesterone; Uterine Neoplasms | 2012 |
Emergency contraception.
Topics: China; Contraception, Postcoital; Contraceptive Agents; Contraceptives, Postcoital; Contraceptives, Postcoital, Synthetic; Ethinyl Estradiol; European Union; Female; Humans; Intrauterine Devices, Copper; Levonorgestrel; Mifepristone; Norpregnadienes; Ovulation; Pregnancy; Pregnancy, Ectopic; Receptors, Progesterone; Time Factors | 2013 |
[Selective progesterone receptor modulators and their therapeutical use].
Topics: Abortion, Induced; Endometriosis; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Pregnancy; Progesterone; Receptors, Progesterone | 2013 |
Ulipristal acetate resembles mifepristone in modulating human fallopian tube function.
Topics: Adrenomedullin; Cilia; Fallopian Tubes; Female; Glycodelin; Glycoproteins; Humans; Mifepristone; Muscle Contraction; Norpregnadienes; Real-Time Polymerase Chain Reaction; Receptors, Progesterone; RNA, Messenger | 2014 |
An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions.
Topics: Acrosome Reaction; Calcium; Humans; In Vitro Techniques; Male; Mifepristone; Norpregnadienes; Sperm Capacitation; Sperm Motility; Spermatozoa | 2014 |
In vitro-assessment of putative antiprogestin activities of phytochemicals and synthetic UV absorbers in human endometrial Ishikawa cells.
Topics: Apigenin; Camphor; Cell Line, Tumor; Coumaric Acids; Endometrium; Female; Hormone Antagonists; Humans; Mifepristone; Norpregnadienes; Phytochemicals; Receptors, Progesterone; Sulfotransferases; Sunscreening Agents | 2015 |
Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model.
Topics: beta Catenin; Cell Adhesion; Cell Line; Cell Proliferation; Cell Survival; Coculture Techniques; Contraception, Postcoital; Contraceptive Agents; Embryo Implantation; Endometrium; Female; Glycogen Synthase Kinase 3 beta; Humans; Mifepristone; Norpregnadienes; Signal Transduction; Spheroids, Cellular | 2017 |
Characterization of Molecular Changes in Endometrium Associated With Chronic Use of Progesterone Receptor Modulators: Ulipristal Acetate Versus Mifepristone.
Topics: Basic Helix-Loop-Helix Transcription Factors; Contraceptives, Postcoital; Endometrium; Female; Hormone Antagonists; Humans; Mifepristone; Norpregnadienes; Receptors, Progesterone; Stromal Cells | 2018 |
A Look Into the Promising World of Selective Progesterone Receptor Modulators.
Topics: Endometrium; Female; Humans; Mifepristone; Norpregnadienes; Receptors, Progesterone | 2018 |
Selective progesterone receptor blockade prevents BRCA1-associated mouse mammary tumors through modulation of epithelial and stromal genes.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Carcinogenesis; Disease Models, Animal; Epithelial Cells; Female; Humans; Mammary Glands, Animal; Mastectomy; Mice; Mifepristone; Norpregnadienes; Receptors, Progesterone; Stromal Cells; Tumor Microenvironment | 2021 |