Page last updated: 2024-09-03

ulipristal acetate and leuprolide

ulipristal acetate has been researched along with leuprolide in 8 studies

Compound Research Comparison

Studies
(ulipristal acetate)
Trials
(ulipristal acetate)
Recent Studies (post-2010)
(ulipristal acetate)
Studies
(leuprolide)
Trials
(leuprolide)
Recent Studies (post-2010) (leuprolide)
376413473,082777772

Protein Interaction Comparison

ProteinTaxonomyulipristal acetate (IC50)leuprolide (IC50)
Gonadotropin-releasing hormone receptorHomo sapiens (human)0.0005
Gonadotropin-releasing hormone receptorRattus norvegicus (Norway rat)0.0006

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Baró, F; Bestel, E; Bouchard, P; Donnez, J; Lemieszczuk, B; Loumaye, E; Nouri, K; Osterloh, I; Selvaggi, L; Sodowski, K; Terrill, P; Tomaszewski, J; Vázquez, F1
Stewart, EA1
Cha, DH; Kim, JY; Kim, ML; Park, JE; Seong, SJ; Shim, JY; Yun, BS1
Postma, MJ; van Asselt, AD; Zakiyah, N1
Chow, TL; Murji, A; Sobel, ML; Whitaker, L1
Allaire, C; Laberge, PY; Leyland, N; Murji, A; Singh, SS; Vilos, GA1
De Milliano, I; Frijlingh, M; Hehenkamp, WJK; Huirne, JAF1
Nakano, Y; Osuga, Y; Takanashi, M; Yamauchi, Y1

Reviews

1 review(s) available for ulipristal acetate and leuprolide

ArticleYear
Selective progesterone receptor modulators (SPRMs) for uterine fibroids.
    The Cochrane database of systematic reviews, 2017, Apr-26, Volume: 4

    Topics: Amenorrhea; Antineoplastic Agents, Hormonal; Estrenes; Female; Humans; Leiomyoma; Leuprolide; Menstruation; Mifepristone; Norpregnadienes; Oximes; Pelvic Pain; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms

2017

Trials

2 trial(s) available for ulipristal acetate and leuprolide

ArticleYear
Ulipristal acetate versus leuprolide acetate for uterine fibroids.
    The New England journal of medicine, 2012, Feb-02, Volume: 366, Issue:5

    Topics: Administration, Oral; Adult; Double-Blind Method; Endometrium; Female; Humans; Injections, Intramuscular; Intention to Treat Analysis; Leiomyoma; Leuprolide; Menorrhagia; Middle Aged; Norpregnadienes; Uterine Neoplasms; Young Adult

2012
Ulipristal acetate compared with leuprorelin acetate for Japanese women with symptomatic uterine fibroids: a phase III randomized controlled trial.
    Fertility and sterility, 2021, Volume: 116, Issue:1

    Topics: Adult; Amenorrhea; Double-Blind Method; Female; Humans; Japan; Leiomyoma; Leuprolide; Menorrhagia; Middle Aged; Norpregnadienes; Time Factors; Treatment Outcome; Uterine Neoplasms

2021

Other Studies

5 other study(ies) available for ulipristal acetate and leuprolide

ArticleYear
Uterine fibroids and evidence-based medicine--not an oxymoron.
    The New England journal of medicine, 2012, Feb-02, Volume: 366, Issue:5

    Topics: Female; Humans; Leiomyoma; Leuprolide; Menorrhagia; Norpregnadienes; Receptors, Progesterone; Uterine Neoplasms

2012
Changes in proliferating and apoptotic markers of leiomyoma following treatment with a selective progesterone receptor modulator or gonadotropin-releasing hormone agonist.
    European journal of obstetrics, gynecology, and reproductive biology, 2015, Volume: 191

    Topics: Adult; Antineoplastic Agents, Hormonal; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Caspase 3; Cell Proliferation; Combined Modality Therapy; Female; Gene Expression Regulation, Neoplastic; Humans; Leiomyoma; Leuprolide; Middle Aged; Myometrium; Neoplasm Proteins; Norpregnadienes; Proliferating Cell Nuclear Antigen; Receptor, Platelet-Derived Growth Factor alpha; Receptors, LHRH; Receptors, Progesterone; Uterine Neoplasms

2015
Ulipristal acetate for pre-operative treatment of moderate-to-severe uterine fibroids in women of reproductive age in The Netherlands: cost minimization analysis and budget impact analysis.
    Journal of medical economics, 2017, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Budgets; Cost Control; Double-Blind Method; Female; Health Care Costs; Humans; Leiomyoma; Leuprolide; Middle Aged; Netherlands; Norpregnadienes; Preoperative Care; Young Adult

2017
Guideline No. 389-Medical Management of Symptomatic Uterine Leiomyomas - An Addendum.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2019, Volume: 41, Issue:10

    Topics: Anemia; Antineoplastic Agents, Hormonal; Contraceptive Agents, Hormonal; Female; Gonadotropin-Releasing Hormone; Hematinics; Humans; Iron Compounds; Leiomyoma; Leuprolide; Liver Function Tests; Menorrhagia; Norpregnadienes; Uterine Neoplasms

2019
Differences in fibroid vascularity after three months of pre-treatment with leuprolide acetate or ulipristal acetate: A pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2020, Volume: 245

    Topics: Adult; Antineoplastic Agents, Hormonal; Female; Humans; Leiomyoma; Leuprolide; Neovascularization, Pathologic; Netherlands; Norpregnadienes; Pilot Projects; Premenopause; Treatment Outcome; Tumor Burden; Uterine Neoplasms

2020