Page last updated: 2024-09-03

ulipristal acetate and asoprisnil

ulipristal acetate has been researched along with asoprisnil in 9 studies

Compound Research Comparison

Studies
(ulipristal acetate)
Trials
(ulipristal acetate)
Recent Studies (post-2010)
(ulipristal acetate)
Studies
(asoprisnil)
Trials
(asoprisnil)
Recent Studies (post-2010) (asoprisnil)
3764134748817

Protein Interaction Comparison

ProteinTaxonomyulipristal acetate (IC50)asoprisnil (IC50)
Estrogen receptorHomo sapiens (human)1.95
Glucocorticoid receptorHomo sapiens (human)0.1025
Progesterone receptorHomo sapiens (human)0.0003
Mineralocorticoid receptor Homo sapiens (human)1.6
Androgen receptorHomo sapiens (human)0.0075

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's8 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Weys, D; Enthoven, M; Golstein, I; Hamersma, H; Rewinkel, J; Scholten, A; van der Rijst, M; van Tilborg, M; Wisse, J1
Sarkar, NN1
Manyonda, I; Talaulikar, VS1
Bastianelli, C; Benagiano, G; Brosens, I; Farris, M1
Abraham, T; Arian, SE; Bartels, CB; Cayton, KC; Chuong, FS; Holthouser, K; Segars, JH1
Centini, G; Kashani, BN; Morelli, SS; Petraglia, F; Weiss, G1
Chow, TL; Murji, A; Sobel, ML; Whitaker, L1
Belland, L; Leyland, N; Murji, A; Singh, SS; von Riedemann, S1
Acosta, K; Binkley, P; Dileep, KV; Nair, HB; Nickisch, K; Santhamma, B; Schenken, R; Zhang, KYJ1

Reviews

6 review(s) available for ulipristal acetate and asoprisnil

ArticleYear
Progesterone and progesterone receptor modulators in the management of symptomatic uterine fibroids.
    European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 165, Issue:2

    Topics: Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Hyperplasia; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone

2012
Selective progesterone receptor modulators: an update.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:10

    Topics: Adenomyosis; Animals; Clinical Trials as Topic; Contraception, Postcoital; Contraceptive Agents, Female; Contraceptives, Postcoital; Endometriosis; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone; Uterine Neoplasms

2014
An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review.
    Clinical obstetrics and gynecology, 2016, Volume: 59, Issue:1

    Topics: Androgens; Aromatase Inhibitors; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Curcumin; Delayed-Action Preparations; Drugs, Chinese Herbal; Estradiol; Estrenes; Estrogen Receptor Antagonists; Evidence-Based Medicine; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Neoadjuvant Therapy; Norpregnadienes; Oximes; Plant Extracts; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tea; Uterine Myomectomy; Uterine Neoplasms; Vitamin D; Vitamins

2016
Role of Medical Management for Uterine Leiomyomas.
    Best practice & research. Clinical obstetrics & gynaecology, 2016, Volume: 34

    Topics: Antifibrinolytic Agents; Aromatase Inhibitors; Cabergoline; Cholecalciferol; Contraceptive Agents, Female; Contraceptives, Oral, Hormonal; Contraceptives, Oral, Synthetic; Danazol; Dopamine Agonists; Ergolines; Estrenes; Estrogen Antagonists; Female; Gestrinone; Gonadotropin-Releasing Hormone; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Patient Care Planning; Selective Estrogen Receptor Modulators; Somatostatin; Tranexamic Acid; Uterine Neoplasms; Vitamins

2016
Selective progesterone receptor modulators (SPRMs) for uterine fibroids.
    The Cochrane database of systematic reviews, 2017, Apr-26, Volume: 4

    Topics: Amenorrhea; Antineoplastic Agents, Hormonal; Estrenes; Female; Humans; Leiomyoma; Leuprolide; Menstruation; Mifepristone; Norpregnadienes; Oximes; Pelvic Pain; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms

2017
The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids.
    American journal of obstetrics and gynecology, 2018, Volume: 218, Issue:6

    Topics: Contraceptive Agents, Female; Disease Management; Estrenes; Female; Forecasting; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Population Growth; Receptors, Progesterone; Steroids; Uterine Neoplasms

2018

Other Studies

3 other study(ies) available for ulipristal acetate and asoprisnil

ArticleYear
11-(pyridinylphenyl)steroids--a new class of mixed-profile progesterone agonists/antagonists.
    Bioorganic & medicinal chemistry, 2008, Mar-15, Volume: 16, Issue:6

    Topics: Ligands; Pregnanes; Progesterone; Receptors, Progesterone; Steroids; Structure-Activity Relationship

2008
The state-of-the-art of emergency contraception with the cutting edge drug.
    German medical science : GMS e-journal, 2011, Volume: 9

    Topics: Contraception, Postcoital; Contraceptive Agents, Female; Estrenes; Female; Gonanes; Humans; Mifepristone; Norpregnadienes; Oximes; Pregnancy; Receptors, Progesterone

2011
EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model.
    Scientific reports, 2019, 11-21, Volume: 9, Issue:1

    Topics: Animals; Cell Proliferation; Contraceptive Agents, Female; Estrenes; Female; Humans; Leiomyoma; Mice; Molecular Docking Simulation; Molecular Structure; Norpregnadienes; Oximes; Progesterone Congeners; Receptors, Progesterone; Structure-Activity Relationship; Uterine Neoplasms; Uterus; Xenograft Model Antitumor Assays

2019