uk 68798 has been researched along with procainamide in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Anderson, MH; Bashir, Y; Camm, AJ; Gibson, S; Heald, S; Kulakowski, P; Malik, M; Paul, V | 1 |
| Honerjäger, P; Schmidt, G | 1 |
| Blackburn, KJ; Burges, RA; Gwilt, M; Higgins, AJ; Milne, AA; Solca, AM | 1 |
| Krafte, DS; Volberg, WA | 1 |
| Baskin, EP; Guinosso, PJ; Hamill, T; Lynch, JJ; Nutt, EM; Salata, JJ; Woods, CM | 1 |
| Lee, EW; Lee, KS; Tsai, TD | 1 |
| Chen, J; Hashimoto, K; Komori, S; Li, B; Tamura, K | 1 |
| Al-Khalidi, H; Brooks, RR; Drexler, AP; Kostreva, DR; Maynard, AE | 1 |
| Osadchii, OE | 2 |
2 review(s) available for uk 68798 and procainamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[New anti-arrhythmia agents].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Phenethylamines; Procainamide; Propanolamines; Sotalol; Sulfonamides; Survival Rate; Tachycardia | 1992 |
17 other study(ies) available for uk 68798 and procainamide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Prediction of antiarrhythmic efficacy of class I and III agents in patients with ventricular tachycardia by signal-averaged ECG analysis.
Topics: Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Conduction System; Humans; Male; Middle Aged; Phenethylamines; Predictive Value of Tests; Procainamide; Signal Processing, Computer-Assisted; Sulfonamides; Tachycardia, Ventricular; Time Factors | 1992 |
Electropharmacology of dofetilide, a new class III agent, in anaesthetised dogs.
Topics: Action Potentials; Anesthesia; Animals; Anti-Arrhythmia Agents; Dogs; Heart; Heart Ventricles; Hemodynamics; Phenethylamines; Potassium Channels; Procainamide; Refractory Period, Electrophysiological; Sotalol; Sulfonamides; Ventricular Fibrillation | 1992 |
Voltage dependence of cardiac delayed rectifier block by methanesulfonamide class III antiarrhythmic agents.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Phenethylamines; Piperidines; Procainamide; Pyridines; Sotalol; Stereoisomerism; Sulfonamides; Ventricular Function | 1994 |
Comparison of binding to rapidly activating delayed rectifier K+ channel, IKr, and effects on myocardial refractoriness for class III antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Binding, Competitive; Chromans; Electrophysiology; Guinea Pigs; Heart Ventricles; Papillary Muscles; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels; Procainamide; Pyridines; Sotalol; Structure-Activity Relationship; Sulfonamides; Tritium | 1995 |
Membrane activity of class III antiarrhythmic compounds; a comparison between ibutilide, d-sotalol, E-4031, sematilide and dofetilide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Phenethylamines; Piperidines; Potassium Channels; Procainamide; Pyridines; Sotalol; Sulfonamides | 1993 |
IK independent class III actions of MS-551 compared with sematilide and dofetilide during reperfusion in anaesthetized rats.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Vessels; Heart Rate; Ischemia; Male; Phenethylamines; Procainamide; Pyrimidinones; Rats; Rats, Sprague-Dawley; Reperfusion; Sulfonamides | 1996 |
Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Male; Methoxamine; Phenethylamines; Piperazines; Procainamide; Quaternary Ammonium Compounds; Rabbits; Sotalol; Sulfonamides | 2000 |
Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; In Vitro Techniques; Perfusion; Phenethylamines; Procainamide; Quinidine; Sulfonamides | 2018 |
Antiarrhythmic drug effects on premature beats are partly determined by prior cardiac activation frequency in perfused guinea-pig heart.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Phenethylamines; Procainamide; Quinidine; Sulfonamides | 2020 |