Compounds > uk 68798
Page last updated: 2024-08-25

uk 68798 and pentamidine

uk 68798 has been researched along with pentamidine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Beekman, HD; de Git, KC; Houtman, MJ; Ijzerman, AP; Linder, T; Stary-Weinzinger, A; Tidwell, RR; van der Heyden, MA; Varkevisser, R; Vos, MA1
Castagné, V; Goineau, S1

Reviews

1 review(s) available for uk 68798 and pentamidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for uk 68798 and pentamidine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.
    British journal of pharmacology, 2013, Volume: 169, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Antiprotozoal Agents; Arrhythmias, Cardiac; Cell Membrane; Dogs; Endocytosis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Kinetics; Membrane Transport Modulators; Mice; Molecular Dynamics Simulation; Pentamidine; Phenethylamines; Potassium Channel Blockers; Recombinant Proteins; Shab Potassium Channels; Structure-Activity Relationship; Sulfonamides

2013
Proarrhythmic risk assessment using conventional and new in vitro assays.
    Regulatory toxicology and pharmacology : RTP, 2017, Volume: 88

    Topics: Action Potentials; Anti-Arrhythmia Agents; Arsenic; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Fluoroquinolones; Humans; In Vitro Techniques; Induced Pluripotent Stem Cells; Long QT Syndrome; Moxifloxacin; Myocytes, Cardiac; Pentamidine; Phenethylamines; Risk Assessment; Sulfonamides

2017