uk 68798 has been researched along with methoxamine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brunden, MN; Buchanan, LV; Gibson, JK; Kabell, G | 1 |
| D'Alonzo, AJ; Darbenzio, RB; Zhu, JL | 1 |
| Al-Khalidi, H; Brooks, RR; Drexler, AP; Kostreva, DR; Maynard, AE | 1 |
| De Clerck, F; Lu, HR; Remeysen, P; Saels, A; Somers, K | 1 |
| Acsai, K; Csanády, M; Dézsi, L; Farkas, A; Farkas, AS; Forster, T; Orosz, S; Papp, JG; Tóth, A; Varró, A | 1 |
| Dai, DZ; Dai, Y; Huang, ZJ; Ji, M; Li, N; Na, T | 1 |
| Andersson, B; Carlsson, L; Linhardt, G; Löfberg, L | 1 |
| Beekman, JD; de Boer, TP; Duker, G; Houtman, MJ; Jonsson, MK; Nalos, L; Peschar, M; Rook, MB; Sartipy, P; Thomsen, MB; van der Heyden, MA; van der Nagel, R; van Veen, TA; Varkevisser, R; Vos, MA | 1 |
| Beekman, JD; Tieland, RG; Van Der Heyden, MA; Varkevisser, R; Vos, MA | 1 |
10 other study(ies) available for uk 68798 and methoxamine
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparative assessment of ibutilide, D-sotalol, clofilium, E-4031, and UK-68,798 in a rabbit model of proarrhythmia.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart Conduction System; Heart Rate; Male; Methoxamine; Phenethylamines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Rabbits; Software; Sotalol; Sulfonamides; Torsades de Pointes | 1993 |
Effects of class III antiarrhythmic agents in an in vitro rabbit model of spontaneous torsades de pointe.
Topics: Acetylcholine; Action Potentials; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Heart; Heart Rate; In Vitro Techniques; Male; Methoxamine; Nadolol; Perfusion; Phenethylamines; Rabbits; Sulfonamides; Torsades de Pointes; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Male; Methoxamine; Phenethylamines; Piperazines; Procainamide; Quaternary Ammonium Compounds; Rabbits; Sotalol; Sulfonamides | 2000 |
Female gender is a risk factor for drug-induced long QT and cardiac arrhythmias in an in vivo rabbit model.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Disease Models, Animal; Electrocardiography; Female; Heart Rate; Incidence; Long QT Syndrome; Male; Methoxamine; Models, Cardiovascular; Phenethylamines; Rabbits; Receptors, Adrenergic, alpha-1; Risk Factors; Sex Factors; Sulfonamides; Treatment Outcome; Women's Health | 2001 |
Importance of extracardiac alpha1-adrenoceptor stimulation in assisting dofetilide to induce torsade de pointes in rabbit hearts.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Electrocardiography; Female; Heart Rate; Heart Ventricles; In Vitro Techniques; Methoxamine; Phenethylamines; Rabbits; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sulfonamides; Torsades de Pointes | 2006 |
Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits.
Topics: Algorithms; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Electrocardiography; Female; Guinea Pigs; Heart Rate; Long QT Syndrome; Male; Membrane Potentials; Methoxamine; Molecular Structure; Myocardial Contraction; Myocytes, Cardiac; Naphthalenes; Phenethylamines; Potassium Channels, Inwardly Rectifying; Rabbits; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sulfonamides; Torsades de Pointes | 2007 |
Assessment of the ion channel-blocking profile of the novel combined ion channel blocker AZD1305 and its proarrhythmic potential versus dofetilide in the methoxamine-sensitized rabbit in vivo.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Inhibitory Concentration 50; Long QT Syndrome; Male; Methoxamine; Phenethylamines; Potassium Channel Blockers; Rabbits; Sulfonamides; Time Factors | 2009 |
Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aza Compounds; Cell Line; Disease Models, Animal; Dogs; Embryonic Stem Cells; Female; Fluoroquinolones; Heart; Heart Block; Humans; Methoxamine; Moxifloxacin; Myocytes, Cardiac; Phenethylamines; Piperidines; Potassium Channel Blockers; Pyridines; Quinolines; Rabbits; Sulfonamides; Torsades de Pointes; Ventricular Remodeling | 2012 |
AV-block and conduction slowing prevail over TdP arrhythmias in the methoxamine-sensitized pro-arrhythmic rabbit model.
Topics: Action Potentials; Anesthetics; Animals; Anti-Arrhythmia Agents; Atrioventricular Block; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Flunarizine; Heart Conduction System; Heart Rate; Methoxamine; Phenethylamines; Rabbits; Sulfonamides; Time Factors; Torsades de Pointes | 2015 |