uk 68798 has been researched along with isoproterenol in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Refsum, H; Tande, PM; Yang, T | 1 |
| Brown, AM; Cantù, F; Napolitano, C; Priori, SG; Schwartz, PJ | 1 |
| Martin, CL; Mcmahon, EG; Palomo, MA | 1 |
| Beatch, GN; Williams, BA | 1 |
| Bril, A; Faivre, JF; Rouanet, S | 1 |
| Brachmann, J; Karolyi, L; Kübler, W; Marschang, H; Schöls, W | 1 |
| Khan, IA | 1 |
| Blessing, WW; De Pasquale, CG; Nalivaiko, E | 1 |
| Kovács, A; Szénási, G | 1 |
| Abi-Gerges, N; Crijns, HJ; Heijman, J; Johnson, DM; Pollard, CE; Valentin, JP; Volders, PG | 1 |
| Dai, DZ; Dai, Y; Hamed, KH; Hu, C; Yu, F | 1 |
| Antoons, G; Beekman, JD; Bourgonje, VJ; de Windt, LJ; Houtman, MJ; Miedema, LF; Schoenmakers, M; Sipido, K; van der Nagel, R; van Veen, TA; Vos, MA | 1 |
| Bányász, T; Hegyi, B; Horváth, B; Kistamás, K; Magyar, J; Nánási, PP; Ruzsnavszky, F; Szentandrássy, N; Váczi, K; Varró, A | 1 |
| Clancy, CE; DeMarco, KR; Harvey, RD; Jeng, MT; Kurokawa, J; López-Redondo, F; Noskov, SY; Perissinotti, LL; Vorobyov, I; Wang, Y; Yang, PC | 1 |
2 review(s) available for uk 68798 and isoproterenol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Atrial stunning: basics and clinical considerations.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function; Atrial Function, Left; Atrial Function, Right; Catheter Ablation; Electric Countershock; Humans; Isoproterenol; Myocardial Stunning; Phenethylamines; Sotalol; Sulfonamides; Thromboembolism; Time Factors; Verapamil | 2003 |
16 other study(ies) available for uk 68798 and isoproterenol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Negative chronotropic effect of a novel class III antiarrhythmic drug, UK-68,798, devoid of beta-blocking action on isolated guinea-pig atria.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Depression, Chemical; Female; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Phenethylamines; Propranolol; Sinoatrial Node; Sulfonamides | 1991 |
Differential response to Na+ channel blockade, beta-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome.
Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Cation Transport Proteins; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Intercellular Signaling Peptides and Proteins; Isoproterenol; Long QT Syndrome; Mexiletine; Mutation; Peptides; Phenethylamines; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Adrenergic, beta; Sodium Channel Blockers; Sodium Channels; Sulfonamides | 1996 |
Comparison of bidisomide, flecainide and dofetilide on action potential duration in isolated canine atria: effect of isoproterenol.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Flecainide; Guinea Pigs; Heart Atria; Isoproterenol; Male; Phenethylamines; Piperidines; Sulfonamides | 1996 |
Magnesium shifts voltage dependence of activation of delayed rectifier I(K) in guinea pig ventricular myocytes.
Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Potassium Channels, Voltage-Gated; Sulfonamides | 1997 |
Comparative effects of glibenclamide, tedisamil, dofetilide, E-4031, and BRL-32872 on protein kinase A-activated chloride current in guinea pig ventricular myocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetylcholine; Animals; Anti-Arrhythmia Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cardiotonic Agents; Chlorides; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Glyburide; Guinea Pigs; Heart Ventricles; Hypoglycemic Agents; Ion Transport; Isoproterenol; Male; Myocardium; Patch-Clamp Techniques; Phenethylamines; Piperidines; Potassium Channels; Propranolol; Pyridines; Sulfonamides | 1998 |
Isoproterenol specifically modulates reverse rate-dependent effects of d,l-sotalol, d-sotalol, and dofetilide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Dogs; Electric Stimulation; Electrophysiology; Heart; Isomerism; Isoproterenol; Membrane Potentials; Phenethylamines; Sotalol; Sulfonamides | 2000 |
Ventricular arrhythmias triggered by alerting stimuli in conscious rabbits pre-treated with dofetilide.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arousal; Arrhythmias, Cardiac; Electrocardiography; Formaldehyde; Heart; Heart Ventricles; Isoproterenol; Motion; Pain; Phenethylamines; Physical Stimulation; Premedication; Propranolol; Rabbits; Stimulation, Chemical; Sulfonamides | 2004 |
Effects of dofetilide and EGIS-7229, an antiarrhythmic agent possessing class III, IV, and IB activities, on myocardial refractoriness in hyperkalemia, hypokalemia, and during beta-adrenergic activation in the rabbit papillary muscle in vitro.
Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Hyperkalemia; Hypokalemia; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenethylamines; Pyridazines; Rabbits; Sulfonamides | 2006 |
I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.
Topics: Action Potentials; Aniline Compounds; Animals; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Dogs; Egtazic Acid; Female; Heart Ventricles; Ion Channels; Isoproterenol; Myocytes, Cardiac; Phenethylamines; Phenyl Ethers; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Adrenergic, beta; Sodium; Sodium-Calcium Exchanger; Sulfonamides | 2010 |
CPU228, a derivative of dofetilide, relieves cardiac dysfunction by normalizing FKBP12.6, NADPH oxidase and protein kinase C epsilon in the myocardium.
Topics: Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Heart Failure; Isoproterenol; Male; NADPH Oxidases; Naphthalenes; Oxidative Stress; Phenethylamines; Phosphorylation; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Sulfonamides; Tacrolimus Binding Proteins; Up-Regulation | 2010 |
Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog.
Topics: Animals; Arrhythmias, Cardiac; Atrioventricular Block; Benzylamines; Calcineurin; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomyopathy, Hypertrophic; Cyclosporine; Disease Models, Animal; Dogs; Isoproterenol; Long QT Syndrome; Myocytes, Cardiac; Patch-Clamp Techniques; Phenethylamines; Phenotype; Phosphorylation; Random Allocation; Sulfonamides; Ventricular Remodeling | 2012 |
Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Chromans; Dogs; Feedback, Physiological; Female; Heart Ventricles; Ion Channels; Ion Transport; Isoproterenol; Lidocaine; Male; Myocytes, Cardiac; Nisoldipine; Phenethylamines; Potassium Channel Blockers; Sulfonamides; Tetrodotoxin; Veratridine | 2015 |
A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias.
Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Arousal; Arrhythmias, Cardiac; Estradiol; Ether-A-Go-Go Potassium Channels; Female; Guinea Pigs; Isoproterenol; Male; Models, Biological; Molecular Docking Simulation; Myocytes, Cardiac; Phenethylamines; Sex Characteristics; Sulfonamides | 2017 |