Page last updated: 2024-08-25

uk 68798 and azimilide

uk 68798 has been researched along with azimilide in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (8.33)	18.2507
2000's	31 (86.11)	29.6817
2010's	2 (5.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
Keserü, GM	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Caron, G; Ermondi, G; Visentin, S	1
Baskin, EP; Lynch, JJ	1
Liu, L; Nattel, S; St-Georges, D	1
Sager, PT	2
Al-Khalidi, H; Brooks, RR; Drexler, AP; Kostreva, DR; Maynard, AE	1
Leunissen, JD; Van Opstal, JM; Vos, MA; Wellens, HJ	1
Camm, AJ	1
Conway, DS; Lip, GY	1
Assadi, MA; Brooks, RR; Caref, EB; El-Hamami, M; El-Sherif, N; Hegazy, M; Restivo, M; Yin, H	1
Reiffel, JA	1
Bianconi, L; Castro, A; Santini, M	1
Brendel, J; Busch, AE; Knobloch, K; Peukert, S; Rosenstein, B; Wirth, KJ	1
Wolbrette, DL	1
Pratt, CM	1
Khan, MH	1
Li, WZ	1
Singh, S	1
Dong, DL; Du, ZM; Li, Z; Song, WH; Wang, HZ; Yang, BF	1
Bleich, M; Brendel, J; Busch, AE; Knobloch, K; Rosenstein, B; Wirth, KJ	1
Pürerfellner, H	1
Brendorp, B; Elming, H; Køber, L; Pedersen, OD; Pehrson, S; Torp-Petersen, C	1
Cvetanovic, I; Ke, X; Lin, C; Ranade, V; Somberg, J	2
Ducouret, P; Ducroq, J; Gérard, JL; Puddu, PE; Rouet, R; Sallé, L; Tabourel, C	1
Carlsson, L; Kowey, PR; Liu, T; Wu, Y; Yan, GX	1
Guo, D; Kowey, PR; Liu, T; Wu, Y; Yan, GX; Zhao, X	1
Grant, AO; Tranquillo, J	1
Ducroq, J; Legrand, JC; Puddu, PE; Rouet, R; Sallé, L	1
Anderson, JL; Bunch, TJ	1

Reviews

12 review(s) available for uk 68798 and azimilide

Article	Year
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 1999, Volume: 14, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Denmark; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Postoperative Complications; Potassium Channel Blockers; Randomized Controlled Trials as Topic; Sulfonamides	1999
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 2000, Volume: 15, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2000
Clinical differences between the newer antiarrhythmic agents. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2000, Volume: 1 Suppl C Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2000
New antiarrhythmic agents for atrial fibrillation. Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Hydantoins; Imidazoles; Imidazolidines; Lidocaine; Phenethylamines; Piperazines; Sulfonamides	2001
New antiarrhythmic drugs for the treatment of atrial fibrillation. Pacing and clinical electrophysiology : PACE, 2002, Volume: 25, Issue:2 Topics: Aminobenzoates; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2002
Risk of proarrhythmia with class III antiarrhythmic agents: sex-based differences and other issues. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Female; Heart Conduction System; Humans; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Risk Assessment; Risk Factors; Sex Factors; Sotalol; Sulfonamides; Tachycardia; Torsades de Pointes	2003
Pure class III agents for prevention of sudden cardiac death. Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:9 Suppl Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Comorbidity; Death, Sudden, Cardiac; Europe; Humans; Hydantoins; Imidazoles; Imidazolidines; Middle Aged; Myocardial Infarction; Phenethylamines; Piperazines; Randomized Controlled Trials as Topic; Sotalol; Sulfonamides; Survival Analysis; Treatment Outcome	2003
Oral class III antiarrhythmics: what is new? Current opinion in cardiology, 2004, Volume: 19, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides; Tachycardia, Supraventricular; Tachycardia, Ventricular; Treatment Outcome	2004
Trials of new antiarrhythmic drugs for maintenance of sinus rhythm in patients with atrial fibrillation. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2004, Volume: 10 Suppl 1 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Cyclopropanes; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Indoles; Oxazines; Phenethylamines; Piperazines; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides	2004
Recent developments in cardiovascular drug therapy: treatment of atrial arrhythmias with new class III drugs and beyond. Current medicinal chemistry. Cardiovascular and hematological agents, 2004, Volume: 2, Issue:1 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Electric Countershock; Electrophysiology; Humans; Hydantoins; Imidazolidines; Pacemaker, Artificial; Phenethylamines; Piperazines; Sulfonamides	2004
A benefit-risk assessment of class III antiarrhythmic agents. Expert opinion on drug safety, 2004, Volume: 3, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Combined Modality Therapy; Defibrillators, Implantable; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazolidines; Ion Transport; Life Tables; Membrane Potentials; Meta-Analysis as Topic; Phenethylamines; Piperazines; Risk Assessment; Sotalol; Sulfonamides; Survival Analysis; Torsades de Pointes; Treatment Outcome	2004
Adjuvant antiarrhythmic therapy in patients with implantable cardioverter defibrillators. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:2 Topics: Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Benzofurans; Defibrillators, Implantable; Humans; Hydantoins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazolidines; Mineralocorticoid Receptor Antagonists; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2014

Other Studies

24 other study(ies) available for uk 68798 and azimilide

Article	Year
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship	2009
Differential atrial versus ventricular activities of class III potassium channel blockers. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Atrial Function; Ferrets; Heart; Hydantoins; Imidazoles; Imidazolidines; Male; Papillary Muscles; Phenethylamines; Piperazines; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Sulfonamides; Temperature; Ventricular Function	1998
Effects of the novel antiarrhythmic agent azimilide on experimental atrial fibrillation and atrial electrophysiologic properties. Cardiovascular research, 1998, Volume: 37, Issue:3 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Distribution; Dogs; Drug Administration Schedule; Electrocardiography; Female; Heart Atria; Heart Rate; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Sulfonamides	1998
Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 223, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Male; Methoxamine; Phenethylamines; Piperazines; Procainamide; Quaternary Ammonium Compounds; Rabbits; Sotalol; Sulfonamides	2000
Azimilide and dofetilide produce similar electrophysiological and proarrhythmic effects in a canine model of Torsade de Pointes arrhythmias. European journal of pharmacology, 2001, Jan-19, Volume: 412, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dogs; Heart Block; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides; Torsades de Pointes; Ventricular Function	2001
Efficacy of azimilide and dofetilide in the dog right atrial enlargement model of atrial flutter. Journal of cardiovascular electrophysiology, 2001, Volume: 12, Issue:9 Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Cardiomegaly; Dogs; Drug Evaluation, Preclinical; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Sulfonamides	2001
Is it rational, reasonable or excessive, and consistently applied? One view of the increasing FDA emphasis on safety first for the release and use of antiarrhythmic drugs for supraventricular arrhythmias. Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:4 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Approval; Drugs, Generic; Heart Ventricles; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides; United States; United States Food and Drug Administration	2001
Electrophysiological and antiarrhythmic effects of the novel I(Kur) channel blockers, S9947 and S20951, on left vs. right pig atrium in vivo in comparison with the I(Kr) blockers dofetilide, azimilide, d,l-sotalol and ibutilide. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Atrial Function; Biphenyl Compounds; Cation Transport Proteins; Electrophysiology; Ether-A-Go-Go Potassium Channels; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Kv1.5 Potassium Channel; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Sotalol; Sulfonamides; Swine; Ventricular Function	2002
[Progress in the clinical use of anti-arrhythmic drugs (I)]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Clinical Trials as Topic; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2003
Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels. Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Delayed Rectifier Potassium Channels; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Hydantoins; Hydrogen-Ion Concentration; Imidazoles; Imidazolidines; Myocardial Ischemia; Oocytes; Patch-Clamp Techniques; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Transfection; Xenopus	2004
Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs. Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:7 Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Biphenyl Compounds; Chromans; Flecainide; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Propafenone; Propanolamines; Sotalol; Sulfonamides; Swine; Ventricular Function	2004
The influence of extracellular acidosis on the effect of IKr blockers. Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10, Issue:1 Topics: Acidosis; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Humans; Hydantoins; Imidazolidines; Myocardial Infarction; Oocytes; Phenethylamines; Piperazines; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Trans-Activators; Xenopus laevis	2005
Electrophysiological effects of azimilide in an in vitro model of simulated-ischemia and reperfusion in guinea-pig ventricular myocardium. European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromans; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Ventricles; Hydantoins; Imidazolidines; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phenethylamines; Piperazines; Potassium Channel Blockers; Sulfonamides; Time Factors	2005
Assessment of the proarrhythmic potential of the novel antiarrhythmic agent AZD7009 and dofetilide in experimental models of torsades de pointes. Journal of cardiovascular electrophysiology, 2005, Volume: 16, Issue:8 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Hydantoins; Imidazolidines; Male; Phenethylamines; Piperazines; Rabbits; Sulfonamides; Torsades de Pointes	2005
The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents. Cardiology, 2007, Volume: 108, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Disease Models, Animal; Electrophysiology; Extracellular Matrix; Female; Hydantoins; Hyperkalemia; Imidazolidines; Oocytes; Phenethylamines; Piperazines; Potassium Channels; Potassium Channels, Voltage-Gated; Probability; Sensitivity and Specificity; Sotalol; Sulfonamides; Xenopus laevis	2007
L-type calcium current reactivation contributes to arrhythmogenesis associated with action potential triangulation. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Guinea Pigs; Hydantoins; Imidazolidines; In Vitro Techniques; Myocytes, Cardiac; Nicardipine; Patch-Clamp Techniques; Phenethylamines; Piperazines; Rabbits; Sulfonamides	2007
Action potential and QT prolongation not sufficient to cause Torsade de Pointes: role of action potential triangulation. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Guinea Pigs; Hydantoins; Imidazolidines; Myocytes, Cardiac; Nicardipine; Patch-Clamp Techniques; Phenethylamines; Piperazines; Rabbits; Sulfonamides; Torsades de Pointes	2007
I(Kr) vs. I(Ks) blockade and arrhythmogenicity in normoxic rabbit Purkinje fibers: does it really make a difference? Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromans; Delayed Rectifier Potassium Channels; Epinephrine; Hydantoins; Imidazolidines; In Vitro Techniques; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purkinje Fibers; Rabbits; Sotalol; Sulfonamides	2011