uk 68798 has been researched along with almokalant in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Abrahamsson, C; Bäärnhielm, C; Carlsson, L; Danielsson, B; Duker, G; Ljung, B; Palmer, M | 1 |
| Abrahamsson, C; Carlsson, L; Duker, G; Lundberg, C | 1 |
| Brown-Woodman, PD; Danielsson, BR; Snow, MD; Webster, WS | 1 |
| Plöen, L; Ritzen, EM; Setchell, BP | 1 |
| Carmeliet, E; Vereecke, J | 1 |
| Amos, GJ; Carlsson, L; Duker, G; Jacobson, I | 1 |
| Abi-Gerges, N; Boyett, MR; Davies, MR; Di Veroli, GY; Zhang, H | 1 |
9 other study(ies) available for uk 68798 and almokalant
| Article | Year |
|---|---|
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Induction of rhythm abnormalities in the fetal rat heart. A tentative mechanism for the embryotoxic effect of the class III antiarrhythmic agent almokalant.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Culture Techniques; Female; Fetal Death; Fetal Heart; Heart; Heart Rate; Myocardium; Phenethylamines; Pregnancy; Propanolamines; Rats; Rats, Sprague-Dawley; Sotalol; Sulfonamides | 1994 |
Electrophysiological and inotropic effects of H 234/09 (almokalant) in vitro: a comparison with two other novel IK blocking drugs, UK-68,798 (dofetilide) and E-4031.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cats; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Phenethylamines; Piperidines; Propanolamines; Purkinje Fibers; Pyridines; Rabbits; Stimulation, Chemical; Sulfonamides | 1993 |
Teratogenic potential of almokalant, dofetilide, and d-sotalol: drugs with potassium channel blocking activity.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Cleft Palate; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Heart Rate, Fetal; Limb Deformities, Congenital; Male; Organ Culture Techniques; Phenethylamines; Potassium Channel Blockers; Pregnancy; Pregnancy Outcome; Propanolamines; Rats; Rats, Sprague-Dawley; Sotalol; Sulfonamides | 1996 |
Reduction in fluid secretion by rat testis by drugs that block potassium channels.
Topics: Analysis of Variance; Androgen-Binding Protein; Animals; Anti-Arrhythmia Agents; Body Weight; Inositol; Magnesium; Male; Organ Size; Phenethylamines; Potassium; Potassium Channel Blockers; Propanolamines; Rats; Rats, Sprague-Dawley; Semen; Sodium; Spermatogenesis; Sulfonamides; Testis | 1998 |
The effect of external pH on the delayed rectifying K+ current in cardiac ventricular myocytes.
Topics: Acids; Animals; Electrophysiology; Extracellular Space; Guinea Pigs; Hydrogen-Ion Concentration; Myocardium; Phenethylamines; Potassium Channel Blockers; Potassium Channels; Propanolamines; Rabbits; Sulfonamides; Time Factors; Ventricular Function | 2000 |
Block of HERG-carried K+ currents by the new repolarization delaying agent H 345/52.
Topics: Action Potentials; Alkanes; Animals; Anti-Arrhythmia Agents; Binding, Competitive; Bridged Bicyclo Compounds; Cation Transport Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fibroblasts; Heart; Humans; Inhibitory Concentration 50; Membrane Potentials; Mice; Models, Animal; Patch-Clamp Techniques; Phenethylamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Predictive Value of Tests; Propanolamines; Sulfonamides; Time Factors; Trans-Activators; Transcriptional Regulator ERG | 2003 |
High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment.
Topics: Action Potentials; Animals; CHO Cells; Cisapride; Computer Simulation; Cricetinae; Cricetulus; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; High-Throughput Screening Assays; Humans; Kinetics; Long QT Syndrome; Markov Chains; Models, Cardiovascular; Patch-Clamp Techniques; Phenethylamines; Potassium Channel Blockers; Propanolamines; Protein Binding; Risk Assessment; Sulfonamides; Torsades de Pointes; Toxicity Tests; Transfection | 2013 |