Page last updated: 2024-08-25

uk 68798 and 4-aminopyridine

uk 68798 has been researched along with 4-aminopyridine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Foster, RW; Isaac, L; McArdle, S; Miller, NM; Small, RC1
Navarro-Polanco, RA; Sánchez-Chapula, JA1
Edwards, G; Högestätt, ED; Larsson, B; Weston, AH; Zygmunt, PM1
Duff, HJ; Geonzon, RA; Gillis, AM; Kulisz, E; Lester, WM; Mathison, HJ1
Gillis, AM; Kulisz, E; Lester, WM; Mathison, HJ1
Duff, H; Swirp, S; Wang, L1
Adamantidis, MM; Bastide, M; Dumotier, BM1
Chun, YW; Hong, C; Knollmann, BC; Mosley, JD; Roden, DM; Stroud, DM; Yang, T1

Other Studies

9 other study(ies) available for uk 68798 and 4-aminopyridine

ArticleYear
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Effects of some K(+)-channel inhibitors on the electrical behaviour of guinea-pig isolated trachealis and on its responses to spasmogenic drugs.
    British journal of pharmacology, 1996, Volume: 117, Issue:8

    Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Charybdotoxin; Electrophysiology; Female; Glyburide; Guinea Pigs; Histamine; Hypoglycemic Agents; Male; Muscle, Smooth; Parasympatholytics; Peptides; Phenethylamines; Potassium Channel Blockers; Scorpion Venoms; Sulfonamides; Trachea

1996
4-aminopyridine activates potassium currents by activation of a muscarinic receptor in feline atrial myocytes.
    The Journal of physiology, 1997, Feb-01, Volume: 498 ( Pt 3)

    Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Animals; Anti-Arrhythmia Agents; Atropine; Biotransformation; Cats; Diuretics; Electrophysiology; Heart Atria; In Vitro Techniques; Indapamide; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Receptors, Muscarinic; Sulfonamides

1997
Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery.
    British journal of pharmacology, 1997, Volume: 121, Issue:1

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Anti-Arrhythmia Agents; Apamin; Binding, Competitive; Biological Factors; Cerebral Cortex; Charybdotoxin; Chromans; Cyclooxygenase Inhibitors; Drug Interactions; Female; Hepatic Artery; Indoles; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sulfonamides

1997
The effects of barium, dofetilide and 4-aminopyridine (4-AP) on ventricular repolarization in normal and hypertrophied rabbit heart.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1

    Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Barium; Electrocardiography; Heart; Hypertrophy, Left Ventricular; Male; Phenethylamines; Rabbits; Sulfonamides; Time Factors

1998
Dispersion of ventricular repolarization and ventricular fibrillation in left ventricular hypertrophy: influence of selective potassium channel blockers.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1

    Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Perfusion; Phenethylamines; Potassium Channel Blockers; Rabbits; Sulfonamides; Time Factors; Ventricular Fibrillation; Ventricular Pressure

2000
Age-dependent response of the electrocardiogram to K(+) channel blockers in mice.
    American journal of physiology. Cell physiology, 2000, Volume: 278, Issue:1

    Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Cation Transport Proteins; Consciousness; DNA-Binding Proteins; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart; Male; Mice; Mice, Transgenic; Myocardium; Phenethylamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Sulfonamides; Temperature; Trans-Activators

2000
"Use-dependent" effects of cisapride on postrest action potentials in rabbit ventricular myocardium.
    European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3

    Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Chromans; Cisapride; Dose-Response Relationship, Drug; Electric Stimulation; Heart Ventricles; In Vitro Techniques; Male; Phenethylamines; Piperidines; Rabbits; Sulfonamides; Time Factors; Ventricular Function

2001
Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.
    Circulation, 2014, Jul-15, Volume: 130, Issue:3

    Topics: 4-Aminopyridine; Action Potentials; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Female; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Models, Animal; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenethylamines; Phosphatidylinositol 3-Kinases; Potassium Channel Blockers; Proto-Oncogene Proteins c-akt; Risk Factors; Signal Transduction; Sulfonamides; Torsades de Pointes; Transfection

2014