uk-453-061 and trifluoromethanesulfonic-acid

uk-453-061 has been researched along with trifluoromethanesulfonic-acid* in 1 studies

Other Studies

1 other study(ies) available for uk-453-061 and trifluoromethanesulfonic-acid

Article	Year
Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media. Organic letters, 2015, Jan-16, Volume: 17, Issue:2 A mild, efficient, and low-temperature palladium-catalyzed cyanation of (hetero)aryl halides and triflates is reported. Previous palladium-catalyzed cyanations of (hetero)aryl halides have required higher temperatures to achieve good catalytic activity. This current reaction allows the cyanation of a general scope of (hetero)aryl halides and triflates at 2-5 mol % catalyst loadings with temperatures ranging from rt to 40 °C. This mild method was applied to the synthesis of lersivirine, a reverse transcriptase inhibitor. Topics: Hydrocarbons, Halogenated; Mesylates; Molecular Structure; Nitriles; Palladium; Pyrazoles; Reverse Transcriptase Inhibitors	2015

Article

Year

Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media.

Organic letters, 2015, Jan-16, Volume: 17, Issue:2

A mild, efficient, and low-temperature palladium-catalyzed cyanation of (hetero)aryl halides and triflates is reported. Previous palladium-catalyzed cyanations of (hetero)aryl halides have required higher temperatures to achieve good catalytic activity. This current reaction allows the cyanation of a general scope of (hetero)aryl halides and triflates at 2-5 mol % catalyst loadings with temperatures ranging from rt to 40 °C. This mild method was applied to the synthesis of lersivirine, a reverse transcriptase inhibitor.

Topics: Hydrocarbons, Halogenated; Mesylates; Molecular Structure; Nitriles; Palladium; Pyrazoles; Reverse Transcriptase Inhibitors

2015