Compounds > uk 34787
Page last updated: 2024-09-05

uk 34787 and indomethacin

uk 34787 has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(uk 34787)		Trials
(uk 34787)		Recent Studies (post-2010)
(uk 34787)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
70029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyuk 34787 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cross, PE; Dickinson, RP; Parry, MJ; Randall, MJ1
Carey, F; Haworth, D1
Hornby, EJ; Skidmore, IF1

Other Studies

3 other study(ies) available for uk 34787 and indomethacin

ArticleYear
Selective thromboxane synthetase inhibitors. 1. 1-[(Aryloxy)alkyl]-1H-imidazoles.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:10

    Topics: Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Imidazoles; Intramolecular Oxidoreductases; Male; Sheep; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship; Thromboxane-A Synthase

1985
Thromboxane synthase inhibition: implications for prostaglandin endoperoxide metabolism. I. Characterisation of an acute intravenous challenge model to measure prostaglandin endoperoxide metabolism.
    Prostaglandins, 1986, Volume: 31, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Epoprostenol; Indoles; Indomethacin; Kinetics; Male; Prostaglandin Endoperoxides; Radioimmunoassay; Rats; Rats, Inbred Strains; Thrombin; Thromboxane A2; Thromboxane-A Synthase

1986
Evidence that prostaglandin endoperoxides can induce platelet aggregation in the absence of thromboxane A2 production.
    Biochemical pharmacology, 1982, Mar-15, Volume: 31, Issue:6

    Topics: Humans; Indoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1982