Page last updated: 2024-09-03

uk 1 and benzoxazoles

uk 1 has been researched along with benzoxazoles in 9 studies

Compound Research Comparison

Studies
(uk 1)
Trials
(uk 1)
Recent Studies (post-2010)
(uk 1)
Studies
(benzoxazoles)
Trials
(benzoxazoles)
Recent Studies (post-2010) (benzoxazoles)
11022,6511001,402

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abe, K; Miyadoh, S; Oi, S; Shibata, K; Taniguchi, M; Ueki, M; Ueno, K1
Kashiwada, M; Shibata, K; Taniguchi, M; Ueki, M1
Shibata, K; Taniguchi, M; Ueki, M1
Brodbelt, JS; Kerwin, SM; Kumar, D; Reyzer, ML1
Jacob, MR; Kerwin, SM; Kumar, D; Reynolds, MB1
Goodlin, VL; Maghami, N; Smith, PJ; Wang, BB1
Brodbelt, JS; Kerwin, S; Mazzitelli, CL; Oehlers, L; Rodriguez, M1
Kerwin, SM; McKee, ML1
Baier, A; Menji, S; Schaughency, P; Smith, PJ; Talley, DC; Tavag, M; Ward, DN1

Other Studies

9 other study(ies) available for uk 1 and benzoxazoles

ArticleYear
UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
    The Journal of antibiotics, 1993, Volume: 46, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Benzoxazoles; Chemical Phenomena; Chemistry, Physical; Drug Screening Assays, Antitumor; Fermentation; Humans; Mice; Streptomyces; Tumor Cells, Cultured

1993
UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. II. Structural elucidation.
    The Journal of antibiotics, 1993, Volume: 46, Issue:7

    Topics: Antibiotics, Antineoplastic; Benzoxazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure

1993
UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. IV. Antifungal action of methyl UK-1.
    The Journal of antibiotics, 1998, Volume: 51, Issue:9

    Topics: Adenine; Antifungal Agents; Bacteria; Benzoxazoles; Cell Division; Microbial Sensitivity Tests; Rhodotorula; Streptomyces

1998
Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry.
    Nucleic acids research, 2001, Nov-01, Volume: 29, Issue:21

    Topics: Antineoplastic Agents; Base Sequence; Benzoxazoles; Binding Sites; Chromomycin A3; Distamycins; DNA; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Metals; Molecular Weight; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides; Plicamycin; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Substrate Specificity; Temperature; Thermodynamics

2001
Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:12

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Benzimidazoles; Benzoxazoles; Cations; Cell Survival; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Magnesium; Staphylococcus aureus; Structure-Activity Relationship; Tumor Cells, Cultured

2002
Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogs.
    Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12

    Topics: Benzoxazoles; Catalysis; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Topoisomerase II Inhibitors

2004
Evaluation of complexes of DNA duplexes and novel benzoxazoles or benzimidazoles by electrospray ionization mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2004, Volume: 15, Issue:11

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Benzimidazoles; Benzoxazoles; Binding Sites; Cations; DNA Adducts; Metals; Spectrometry, Mass, Electrospray Ionization

2004
Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2'-hydroxyphenyl)benzoxazole analogs of UK-1.
    Bioorganic & medicinal chemistry, 2008, Feb-15, Volume: 16, Issue:4

    Topics: Antineoplastic Agents; Benzoxazoles; Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Copper; Female; Humans; Lung Neoplasms; Magnesium; Metals; Structure-Activity Relationship

2008
UK-1 and structural analogs are potent inhibitors of hepatitis C virus replication.
    Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2

    Topics: Antiviral Agents; Benzoxazoles; Dose-Response Relationship, Drug; Hepacivirus; Humans; RNA Helicases; Virus Replication

2014