uic-94003 has been researched along with indinavir sulfate in 4 studies
| Studies (uic-94003) | Trials (uic-94003) | Recent Studies (post-2010) (uic-94003) | Studies (indinavir sulfate) | Trials (indinavir sulfate) | Recent Studies (post-2010) (indinavir sulfate) |
|---|---|---|---|---|---|
| 18 | 0 | 4 | 1,834 | 328 | 146 |
| Protein | Taxonomy | uic-94003 (IC50) | indinavir sulfate (IC50) |
|---|---|---|---|
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (BRU ISOLATE) | 0.0004 | |
| Gag polyprotein | HIV-1 M:B_MN | 0.02 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.2 | |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | 0.0261 | |
| Substance-K receptor | Homo sapiens (human) | 5.101 | |
| Thromboxane-A synthase | Homo sapiens (human) | 1.851 | |
| Protease | Human immunodeficiency virus 1 | 0.0349 | |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 7.8 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 3.8 | |
| Protease | Human immunodeficiency virus 1 | 0.0044 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azijn, H; de Bethune, MP; de Kock, HA; De Meyer, S; Jonckers, TH; King, NM; Pauwels, R; Peeters, A; Pille, GM; Prabu-Jeyabalan, M; Schiffer, CA; Surleraux, DL; Tahri, A; Verschueren, WG; Wigerinck, PB | 1 |
| Baldridge, A; Gemma, S; Ghosh, AK; Koh, Y; Kovalevsky, AY; Mitsuya, H; Wang, YF; Weber, IT | 1 |
| Amano, M; Anderson, DD; Baldridge, A; Chumanevich, AA; Ghosh, AK; Hong, L; Koh, Y; Kovalevsky, AY; Kulkarni, S; Mitsuya, H; Tang, J; Tojo, Y; Wang, YF; Weber, IT | 1 |
| DeGoey, DA; Randolph, JT | 1 |
1 review(s) available for uic-94003 and indinavir sulfate
| Article | Year |
|---|---|
Peptidomimetic inhibitors of HIV protease.
Topics: Anti-HIV Agents; Atazanavir Sulfate; Carbamates; Clinical Trials as Topic; Dipeptides; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lopinavir; Models, Molecular; Molecular Mimicry; Molecular Structure; Nelfinavir; Oligopeptides; Organophosphates; Peptides; Phenylbutyrates; Pyridines; Pyrimidinones; Ritonavir; Saquinavir; Sulfonamides; Urethane | 2004 |
3 other study(ies) available for uic-94003 and indinavir sulfate
| Article | Year |
|---|---|
Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor.
Topics: Administration, Oral; Animals; Biological Availability; Cell Line; Crystallography, X-Ray; Darunavir; Dogs; Drug Resistance, Multiple, Viral; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; In Vitro Techniques; Microsomes, Liver; Models, Molecular; Molecular Conformation; Mutation; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Thermodynamics | 2005 |
Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies.
Topics: Antiviral Agents; Cell Survival; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Ethers, Cyclic; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Hydrogen Bonding; Ligands; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Polyesters; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Water | 2008 |
Design, synthesis, protein-ligand X-ray structure, and biological evaluation of a series of novel macrocyclic human immunodeficiency virus-1 protease inhibitors to combat drug resistance.
Topics: Anti-HIV Agents; Cell Line; Crystallography, X-Ray; Drug Design; Drug Resistance, Viral; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Ligands; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Mutation | 2009 |