uh-ah 37 has been researched along with pirenzepine in 2 studies
*Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. [MeSH]
*Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. [MeSH]
Studies (uh-ah 37) | Trials (uh-ah 37) | Recent Studies (post-2010) (uh-ah 37) | Studies (pirenzepine) | Trials (pirenzepine) | Recent Studies (post-2010) (pirenzepine) |
---|---|---|---|---|---|
7 | 0 | 0 | 3,812 | 587 | 140 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brann, MR; Dörje, F; Lambrecht, G; Mutschler, E; Wess, J | 1 |
Ellis, J; Seidenberg, M | 1 |
2 other study(ies) available for uh-ah 37 and pirenzepine
Article | Year |
---|---|
Selectivity profile of the novel muscarinic antagonist UH-AH 37 determined by the use of cloned receptors and isolated tissue preparations.
Topics: Animals; Benzodiazepinones; Cells, Cultured; Cloning, Molecular; Cricetinae; Dibenzazepines; Female; Humans; In Vitro Techniques; Kinetics; Male; Membranes; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Species Specificity | 1991 |
Site-directed mutagenesis implicates a threonine residue in TM6 in the subtype selectivities of UH-AH 37 and pirenzepine at muscarinic receptors.
Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Binding, Competitive; COS Cells; Dibenzazepines; Humans; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Parasympatholytics; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M5; Receptors, Muscarinic; Sequence Homology, Amino Acid; Threonine; Transfection | 2000 |