Page last updated: 2024-08-26

uftoral and levoleucovorin

uftoral has been researched along with levoleucovorin in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's29 (35.80)18.2507
2000's47 (58.02)29.6817
2010's5 (6.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ichikura, T; Okusa, Y; Tamakuma, S; Tomimatsu, S; Uefuji, K; Yahara, T1
Rustum, YM1
Pazdur, R3
Blanco, E; Colmenarejo, A; Crespo, MC; de Castro, J; Espinosa, E; Espinosa, J; Feliu, J; Garcia Girón, C; González Barón, M; Juárez, F; Martinez, B; Ordóñez, A1
Belón, J; Blanco, E; Espinosa, E; Feliu, J; Garcia Alfonso, P; Garcia Girón, C; Garrido, P; González Barón, M; Jara, C; Ruiz, A; Vincent, JM; Zamora, P1
Bready, B; Diaz-Canton, E; Ho, DH; Lassere, Y; Pazdur, R1
Hioki, M; Hirano, S; Hirata, T; Hisayoshi, T; Kutsukata, N; Masuda, S; Yamagishi, S; Yamamoto, S; Yamashita, Y1
Hata, K; Kaganoi, J; Nanbu, H; Nishitai, R; Ohsumi, K; Tokunaga, Y1
Birkhofer, MJ; Meropol, NJ; Noel, D; Sonnichsen, DS1
DeMario, MD; Ratain, MJ1
Jones, J; Mamounas, EP; Wickerham, DL; Wieand, HS; Wolmark, N1
Skillings, JR1
Carmichael, J1
Abad, A; Aranda, E; Diaz-Rubio, E; Fernandez-Martos, C; Gallén, M; Marcuello, E; Martín, C; Navarro, M; Sastre, J1
Diaz-Canton, E; Pazdur, R1
Minsky, BD1
Ayala, F; Casado, A; Diaz-Rubio, E; López-Martin, JA; Martin, M; Nieto, Y; Rodriguez-Lescure, A1
Belón, J; de Castro, J; Espinosa, E; Feliu, J; García Alfonso, P; García Girón, C; Garrido, P; González Barón, M; Lomas, M; Ordóñez, A; Zamora, P1
Kim, BS; Kim, JG; Kim, JS; Kim, YH; Park, YT; Shin, SW1
Mani, S1
Abe, T; Aiba, K; Furue, H; Hasegawa, K; Horikoshi, N; Kanamaru, R; Kurihara, M; Niitani, H; Ogawa, M; Taguchi, T; Takeda, S1
Ebuchi, M; Kudo, T; Kuwabara, H; Maruyama, M; Sugano, N; Yoshida, T1
Benner, SE; Canetta, R; Hoff, PM; Pazdur, R1
Birkhofer, MJ; Ferreira, I; Meropol, NJ; Noel, D; Sonnichsen, DS1
Benner, S; DeMario, MD; Fleming, GF; Johnson, S; Lebwohl, D; Mani, S; Melton, K; Ratain, MJ; Vogelzang, NJ; Vokes, EE1
Brito, R; Hoff, PM; Medgyesy, D; Pazdur, R; Royce, M1
Hoff, PM; Lassere, Y; Pazdur, R1
Laohavinij, S; Maoleekoonpairoj, S; Thavichaigarn, P; Thongprasert, S1
Chazard, M; Coudray, AM; de Gramont, A; Gespach, C; Louvet, C; Prévost, S; Raymond, E; Tournigand, C1
Alberts, D; Brooks, D; Damle, B; Ferreira, I; Kaul, S; Pazdur, R; Ravandi, F; Sonnichsen, D; Stewart, D1
Langer, CJ1
Ioka, Z; Nakane, Y; Nakano, K; Osaka, Y; Sako, H; Takemura, N; Tanabe, S; Tsuchiya, K1
Daijo, H; Hoshino, T; Inokuma, S; Ishida, H; Nakada, H; Ohsawa, T; Takeuchi, I1
Chen, JS; Hsu, KC; Tang, R; Wang, JY; Yang, TS1
Hirayama, R; Ichikawa, W; Nihei, Z; Sasaki, Y; Shirota, Y; Sugihara, K; Takahashi, T; Uetake, H; Yamada, H1
Handa, R; Iijima, S; Kato, T; Kikkawa, N; Kurokawa, E; Naoi, Y; Oshima, S; Tsujie, M; Yamamoto, H1
Handa, R; Iijima, S; Kato, T; Kikkawa, N; Kurokawa, E; Naoi, Y; Ohshima, S; Tsujie, M; Yamamoto, H1
Enomoto, M; Higuchi, T; Sugihara, K; Uetake, H1
Aihara, T; Fukuhara, A; Kouno, T; Murayama, M; Nakagawa, K; Nakamura, E; Niida, M; Nishimoto, Y; Nozaki, H; Syouda, S; Watanabe, Y; Yagyu, T; Yasuoka, H1
Anazawa, S; Hirai, K; Kawahara, H; Ogawa, M; Sakuyama, T; Sato, K; Takao, Y; Yamazaki, Y; Yokoyama, M1
Hashimoto, D; Inokuma, S; Ishida, H; Nakada, H; Ohsawa, T; Shirakawa, K; Yamada, H; Yokoyama, M1
Enomoto, M; Higuchi, T; Iida, S; Sugihara, K; Tsunozaki, H; Uetake, H; Yasuno, M1
Fleming, GF; Gupta, S; Mauer, AM; Ryan, CW; Samuels, BL; Taber, DA1
Choi, CW; Choi, IK; Kim, BS; Kim, JS; Kim, SJ; Kim, YH; Oh, SC; Park, KH; Seo, JH; Shin, SW; Yoon, SY1
Chan, WK; Chao, Y; Chen, WS; Chi, KH; Jiang, JK; Lee, RC; Li, AF; Lin, JK; Lin, TC; Wang, HS; Wang, LW; Yang, SH; Yen, SH1
Endo, Y; Fukushima, T; Kanazawa, M; Ohki, S; Ohshima, T; Saito, M; Sekikawa, K; Takenoshita, S1
Beauchamp, RD; Berlin, J; Blanke, CD; Caillouette, C; Chakravarthy, B; Choy, H; Leach, S; Roberts, J; Shyr, Y; Tarpley, J; Tedesco, KL; Teng, M; Wyman, K1
Johnstone, P; Kauh, J1
Hatakeyama, K; Muneoka, K; Okumura, S; Shirai, Y; Wakai, T; Yokoyama, N1
Fujii, H; Hasegawa, S; Hatano, E; Ikai, I; Kawashima, K; Matsumoto, S; Satoh, S; Shimahara, Y1
Akasaka, Y; Hata, Y; Honda, S; Ito, T; Matsuoka, S; Nakajima, N; Ohmori, K; Sano, F; Yokoyama, R1
Fukasawa, M; Kano, N; Kitagawa, M; Kitahama, S; Koneri, K; Kuroki, M; Kusanagi, H; Takeshi, A; Watanabe, Y; Yamamoto, S1
Ichimori, T; Ishikawa, M; Ishikura, H; Kimura, S; Okitsu, H; Sakata, A; Seike, J; Yuasa, Y1
Fujiwara, H; Hamabe, Y; Ishida, T; Kaji, M; Mukai, H; Mukubou, H; Onishi, N; Sato, S; Toyokawa, A; Tsujimura, T; Tsukamoto, T; Wakahara, T; Wakita, K; Watanabe, A1
Ito, T; Iwase, K; Kainuma, S; Kanou, T; Mizuno, H; Mizushima, T; Nakamori, Y; Ozawa, H; Souma, Y; Yamanaka, H1
Akasu, T1
Maeda, Y; Makuuchi, H; Murayama, C; Sadahiro, S; Suzuki, T1
Ishigame, T; Ishii, Y; Okayama, H; Takahashi, M1
Hatakeyama, K; Muneoka, K; Sakata, J; Shirai, Y; Wakai, T; Yokoyama, N1
Akita, H; Ishida, H; Kabuto, T; Nakaguchi, K; Watanabe, Y1
Morimoto, N; Shibaki, T1
Arai, Y; Inaba, Y; Kanemitsu, Y; Muro, K; Nishiofuku, H; Oyama, T; Sato, Y; Sawaki, A; Shimamoto, H; Yamaura, H1
Iwamoto, S; Yoshioka, K1
Hoki, M; Ito, T; Iwamoto, T; Iwase, K; Kanou, T; Mizuno, H; Mizushima, T; Nakamori, Y; Ozawa, H; Souma, Y1
Ando, T; Goto, H; Ina, K; Inagaki, J; Ito, A; Kataoka, T; Kato, H; Nagao, S; Niwa, Y; Ohkita, T1
Fuji, K; Hirazuka, T; Ikeda, T; Kahno, T; Mashino, K; Ninomiya, M; Shibahara, K; Yamamoto, M1
Shoji, Y; Toyooka, M1
Komatsu, Y1
Furukawa, T; Ishii, H; Maruyama, M; Ohata, M; Ohori, M; Saito, N; Sato, H; Tokura, Y1
Geboes, K; Van Cutsem, E1
Baatrup, G; Bisgaard, C; Hansen, F; Jacobsen, A; Pfeiffer, P; Qvortrup, C; Rasmussen, P; Vestermark, LW1
Abbruzzese, JL; Anthony, L; Hoff, PM; Kopetz, S; Langleben, A; Lassere, Y; Rinaldi, D; Thomas, MB; Wolff, RA1
Aerts, JG; Gras, J; Hoogsteden, H; Pouw, E; Pronk, T; Salomé, J; Schmitz, PI; Surmont, V; Tan, KY; van Klaveren, RJ; Vernhout, R1
Matsui, N; Nakao, K; Tsunoda, A; Tsunoda, Y; Watanabe, M1
Arita, M; Kuga, Y; Miwata, T; Moriya, T; Murakami, E; Nishida, T; Numata, Y; Ohya, T; Okanobu, H; Tanaka, T; Yoshimi, S1
Kawai, K; Kitayama, J; Nagawa, H; Sunami, E; Yasuda, K1
Boku, N; Endo, T; Ikejiri, K; Kameoka, S; Kinugasa, Y; Kotake, K; Matsubara, Y; Mochizuki, H; Mochizuki, I; Nakamoto, Y; Shinozaki, H; Sugihara, K; Takagane, A; Takahashi, K; Takahashi, Y; Takii, Y; Takiuchi, H; Tomita, N; Watanabe, M; Watanabe, T1
Chamorey, E; Dahan, L; Evesque, L; Follana, P; Francois, E; Mari, V; Michel, C; Perrier, H; Seitz, JF; Smith, D1

Reviews

11 review(s) available for uftoral and levoleucovorin

ArticleYear
Current and future directions in adjuvant combined-modality therapy of rectal cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations; Fluorouracil; Forecasting; Humans; Leucovorin; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Rectal Neoplasms; Tegafur; Uracil

1997
UFT and leucovorin: a review of its clinical development and therapeutic potential in the oral treatment of cancer.
    Anti-cancer drugs, 1998, Volume: 9, Issue:6

    Topics: Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Drug Combinations; Humans; Leucovorin; Lung Neoplasms; Neoplasms; Stomach Neoplasms; Tegafur; Uracil

1998
Oral fluoropoyrimidines.
    Seminars in oncology, 1999, Volume: 26, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil

1999
Tegafur/uracil + calcium folinate in colorectal cancer: double modulation of fluorouracil.
    Drugs, 1999, Volume: 58 Suppl 3

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Leucovorin; Tegafur; Uracil

1999
The role of UFT and the combination of UFT/leucovorin in non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2001, Volume: 34, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Drug Combinations; Humans; Leucovorin; Lung Neoplasms; Tegafur; Treatment Outcome; Uracil

2001
[Chemotherapy for colorectal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Prospective Studies; Randomized Controlled Trials as Topic; Tegafur; Uracil

2003
[Second-line chemotherapy for advanced colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Quality of Life; Survival Rate; Tegafur; Uracil

2005
Commentary on Wang et al., "Pre-operative chemotherapy with oral tegafur-uracil and leucovorin for rectal cancer" (J Surg Oncol 89: 256-263).
    Journal of surgical oncology, 2005, May-01, Volume: 90, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Preoperative Care; Rectal Neoplasms; Survival Rate; Tegafur; Uracil

2005
[Adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Evidence-Based Medicine; Fluorouracil; Guidelines as Topic; Humans; Leucovorin; Lymph Node Excision; Neoplasm Staging; Survival Rate; Tegafur; Uracil

2006
[Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Europe; Evidence-Based Medicine; Fluorouracil; Humans; Irinotecan; Japan; Leucovorin; Neoplasm Staging; Oxonic Acid; Practice Guidelines as Topic; Rectal Neoplasms; Tegafur; United States; Uracil

2007
The multidisciplinary management of gastrointestinal cancer. The integration of cytotoxics and biologicals in the treatment of metastatic colorectal cancer.
    Best practice & research. Clinical gastroenterology, 2007, Volume: 21, Issue:6

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Death; Cell Survival; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; ErbB Receptors; Fluorouracil; Humans; Leucovorin; Neoplasm Metastasis; Tegafur; Treatment Outcome; Uracil; Vascular Endothelial Growth Factor A

2007

Trials

32 trial(s) available for uftoral and levoleucovorin

ArticleYear
Thymidylate synthase inhibition by an oral regimen consisting of tegafur-uracil (UFT) and low-dose leucovorin for patients with gastric cancer.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:5

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Humans; Leucovorin; Male; Neoplasm Staging; Prospective Studies; Stomach Neoplasms; Tegafur; Thymidylate Synthase; Uracil

1996
Phase II study of UFT plus leucovorin in colorectal cancer.
    Oncology, 1997, Volume: 54 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Drug Combinations; Humans; Leucovorin; Neoplasm Metastasis; Survival Analysis; Tegafur; Uracil

1997
UFT modulated with leucovorin in advanced colorectal cancer: Oncopaz experience.
    Oncology, 1997, Volume: 54 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Humans; Leucovorin; Tegafur; Uracil

1997
Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast.
    Oncology, 1997, Volume: 54 Suppl 1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Combinations; Etoposide; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Middle Aged; Stomach Neoplasms; Tegafur; Uracil

1997
Phase I trial of uracil-tegafur (UFT) plus oral leucovorin: 14-day schedule.
    Investigational new drugs, 1997, Volume: 15, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Tegafur; Uracil

1997
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
    Journal of surgical oncology, 1997, Volume: 66, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Mitomycin; Postoperative Period; Rectal Neoplasms; Survival Rate; Tegafur; Uracil

1997
Oral UFT plus leucovorin in patients with relapsed or refractory colorectal cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Middle Aged; Tegafur; Uracil

1997
Phase I and pharmacokinetic evaluations of UFT plus oral leucovorin.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Drug Combinations; Fluorouracil; Humans; Leucovorin; Neoplasms; Tegafur; Tetrahydrofolates; Uracil

1997
5-FU or UFT combined with leucovorin for previously untreated metastatic colorectal Ca.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Tegafur; Uracil

1997
UFT plus leucovorin vs 5-FU plus leucovorin for metastatic colorectal cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Middle Aged; Tegafur; Uracil

1997
A preliminary report of a phase II trial. UFT plus oral folinic acid as therapy for metastatic colorectal cancer in older patients. Spanish Group for the Treatment of Gastrointestinal Tumors (TTd Group).
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Aged; Aged, 80 and over; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Male; Nausea; Survival Analysis; Tegafur; Treatment Outcome; Uracil

1997
Preoperative combined oral UFT plus leucovorin and radiation therapy for rectal cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combinations; Feasibility Studies; Fluorouracil; Humans; Leucovorin; Radiotherapy Dosage; Rectal Neoplasms; Tegafur; Uracil

1997
The UFT/leucovorin/etoposide regimen for the treatment of advanced gastric cancer. Oncopaz Cooperative Group.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Anemia; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Combinations; Etoposide; Female; Forecasting; Humans; Leucovorin; Male; Nausea; Stomach Neoplasms; Survival Rate; Tegafur; Uracil

1997
A phase II trial. Oral UFT and leucovorin in patients with advanced gastric carcinoma.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Diarrhea; Drug Combinations; Female; Follow-Up Studies; Humans; Leucovorin; Leukopenia; Male; Middle Aged; Nausea; Stomach Neoplasms; Survival Rate; Tegafur; Treatment Outcome; Uracil

1997
UFT plus leucovorin in advanced hepatobiliary tumors and pancreatic adenocarcinomas.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adenocarcinoma; Adult; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Cholangiocarcinoma; Drug Combinations; Humans; Leucovorin; Liver Neoplasms; Pancreatic Neoplasms; Quality of Life; Tegafur; Treatment Outcome; Uracil

1997
[Phase I study of orally administered UFT plus l-leucovorin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Female; Gastrointestinal Neoplasms; Humans; Leucovorin; Male; Middle Aged; Nausea; Stomach Neoplasms; Tegafur; Uracil; Vomiting

1998
Bioavailability and phase II study of oral UFT plus leucovorin in patients with relapsed or refractory colorectal cancer.
    Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biological Availability; Colorectal Neoplasms; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Tegafur; Uracil

1999
A phase I study of oral uracil/ftorafur (UFT) plus leucovorin and bis-acetato-ammine-dichloro-cyclohexylamine-platinum IV (JM-216) each given over 14 days every 28 days.
    Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:5

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Humans; Leucovorin; Neoplasms; Organoplatinum Compounds; Tegafur; Treatment Outcome; Uracil; Vomiting

1999
Efficacy of UFT plus oral leucovorin in advanced colorectal cancer: a multicenter study.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2000, Volume: 83, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Prognosis; Severity of Illness Index; Survival Rate; Tegafur; Treatment Outcome; Uracil

2000
Effect of food on the oral bioavailability of UFT and leucovorin in cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Biological Availability; Colorectal Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Fasting; Female; Fluorouracil; Food; Humans; Leucovorin; Male; Middle Aged; Tegafur; Tetrahydrofolates; Time Factors; Uracil

2001
Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.
    British journal of cancer, 2003, Oct-20, Volume: 89, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Male; Middle Aged; Orotate Phosphoribosyltransferase; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Tegafur; Treatment Outcome; Uracil

2003
A phase II trial of UFT and leucovorin in women 65 years and older with advanced breast cancer.
    American journal of clinical oncology, 2005, Volume: 28, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Drug Combinations; Female; Humans; Leucovorin; Tegafur; Uracil

2005
Docetaxel (Taxotere), cisplatin, UFT, and leucovorin combination chemotherapy in advanced gastric cancer.
    British journal of cancer, 2005, Mar-14, Volume: 92, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Stomach Neoplasms; Survival Analysis; Taxoids; Tegafur; Treatment Outcome; Uracil

2005
Phase I trial of Orzel (UFT plus leucovorin), cisplatin, and radiotherapy in the treatment of potentially resectable esophageal cancer.
    International journal of radiation oncology, biology, physics, 2005, Apr-01, Volume: 61, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Combinations; Esophageal Neoplasms; Female; Humans; Leucovorin; Male; Middle Aged; Radiation-Sensitizing Agents; Tegafur; Uracil

2005
[Pharmacokinetic modulating chemotherapy highly effective for colorectal carcinoma metastases to multiple organs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronotherapy; Colorectal Neoplasms; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Tegafur; Uracil

2005
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Nausea; Rectal Neoplasms; Survival Rate; Tegafur; Uracil; Vomiting, Anticipatory

2005
[Feasibility of weekday-on/weekend-off oral UFT/Leucovorin schedule as postoperative adjuvant chemotherapy for colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Tegafur; Uracil

2006
Long-term results of a phase II trial of high-dose radiotherapy (60 Gy) and UFT/l-leucovorin in patients with non-resectable locally advanced rectal cancer (LARC).
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dose Fractionation, Radiation; Drug Combinations; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Preoperative Care; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Rectal Neoplasms; Survival Analysis; Tegafur; Treatment Outcome; Uracil

2008
A phase II study of UFT with leucovorin administered as a twice daily schedule in the treatment of patients with metastatic colorectal cancer.
    British journal of cancer, 2008, Sep-02, Volume: 99, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Survival Analysis; Tegafur; Treatment Outcome; Uracil

2008
Oral UFT, etoposide and leucovorin in recurrent non-small cell lung cancer: a non-randomized phase II study.
    Lung cancer (Amsterdam, Netherlands), 2009, Volume: 66, Issue:3

    Topics: Administration, Oral; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Combinations; Etoposide; Female; Humans; Kaplan-Meier Estimate; Leucovorin; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Neutropenia; Tegafur; Uracil

2009
Safety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial.
    British journal of cancer, 2012, Mar-27, Volume: 106, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Oxonic Acid; Tegafur; Uracil

2012
Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study.
    Journal of chemotherapy (Florence, Italy), 2012, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Colorectal Neoplasms; Drug Combinations; Drug Monitoring; Female; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Grading; Salvage Therapy; Survival Analysis; Tegafur; Tumor Burden; Uracil

2012

Other Studies

38 other study(ies) available for uftoral and levoleucovorin

ArticleYear
Mechanism-based improvement in the therapeutic selectivity of 5-FU prodrug alone and under conditions of metabolic modulation.
    Oncology, 1997, Volume: 54 Suppl 1

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Drug Synergism; Fluorouracil; Leucovorin; Prodrugs; Rats; Tegafur; Uracil

1997
[A case of far-advanced gastric cancer treated with neoadjuvant combination chemotherapy of UFT, low-dose CDDP and leucovorin, followed by subtotal gastrectomy with curative intent].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Gastrectomy; Humans; Leucovorin; Male; Neoplasm Invasiveness; Portal Vein; Stomach Neoplasms; Tegafur; Uracil

1997
UFT: East meets West in drug development.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Drug Therapy, Combination; Humans; Japan; Leucovorin; Neoplasms; Tegafur; United States; Uracil

1997
Rationale for phase I study of UFT plus leucovorin and oral JM-216.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Combinations; Drug Therapy, Combination; Humans; Leucovorin; Organoplatinum Compounds; Tegafur; Uracil

1997
Future directions in the adjuvant treatment of colon cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Combinations; Drug Therapy, Combination; Fluorouracil; Forecasting; Humans; Leucovorin; Tegafur; Uracil

1997
Preliminary results. UFT/methotrexate/leucovorin for breast Ca patients in progression after HDCT/PBPC support.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Anemia; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diarrhea; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neutropenia; Survival Rate; Tegafur; Uracil

1997
[Preoperative chemotherapy for advanced colorectal carcinomas--comparison of histological effect between UFT + leucovorin tablet and UFT alone].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:5

    Topics: Administration, Oral; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Rectal Neoplasms; Tablets; Tegafur; Uracil

1998
Synergistic antitumoral activity of combined UFT, folinic acid and oxaliplatin against human colorectal HT29 cell xenografts in athymic nude mice.
    Anti-cancer drugs, 2000, Volume: 11, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colorectal Neoplasms; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Female; HT29 Cells; Humans; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Tegafur; Transplantation, Heterologous; Uracil

2000
[A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Leucovorin; Liver Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms; Tegafur; Uracil

2002
[A case of liver metastasis of rectal cancer demonstrating complete response to 5-FU + Leucovorin + UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Remission Induction; Tegafur; Uracil

2002
Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer.
    Japanese journal of clinical oncology, 2002, Volume: 32, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Salvage Therapy; Tegafur; Uracil

2002
Oral tegafur-uracil plus leucovorin in metastatic colorectal cancer: clinical insights. Proceedings of a roundtable expert meeting. October 2002, Nice, France.
    Anti-cancer drugs, 2003, Volume: 14 Suppl 2

    Topics: Adenocarcinoma; Antineoplastic Agents; Colorectal Neoplasms; Drug Combinations; Humans; Leucovorin; Neoplasm Metastasis; Tegafur; Uracil

2003
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Rectal Neoplasms; Tegafur; Uracil

2003
[Long-term survival after neck lymph node metastases from sigmoid colon cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colon, Sigmoid; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Neck; Sigmoid Neoplasms; Survivors; Tegafur; Uracil

2003
[A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Pleurisy; Quality of Life; Tegafur; Uracil

2004
[Home chemotherapy by concomitant UFT + Leucovorin (po.) in postoperative colorectal cancer patients assessed with Dukes D and curability C colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Drug Administration Schedule; Drug Combinations; Female; Home Care Services, Hospital-Based; Humans; Leucovorin; Leukopenia; Male; Middle Aged; Nausea; Postoperative Care; Tegafur; Uracil; Vomiting, Anticipatory

2004
[Tumoral dihydropyrimidine dehydrogenase expression and efficacy of 5-fluorouracil plus leucovorin plus UFT therapy in patients with colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Tegafur; Uracil

2004
Pre-operative chemoradiotherapy with oral tegafur-uracil and leucovorin for rectal cancer.
    Journal of surgical oncology, 2005, Mar-15, Volume: 89, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Palliative Care; Rectal Neoplasms; Survival Rate; Tegafur; Uracil

2005
[A case of liver metastases from cecal cancer successfully treated with fluorouracil and folinic acid (UFT/LV)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Chemotherapy, Adjuvant; Colectomy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Tegafur; Uracil

2005
[Combined chemotherapy with oral leucovorin (LV) + tegafur/uracil (UFT) and hepatic arterial infusion (HAI) therapy for liver metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil

2005
[A case of multiple lung metastases of sigmoid colon cancer responding well to oral UFT+leucovorin therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colon, Sigmoid; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Lung Neoplasms; Middle Aged; Pneumonectomy; Quality of Life; Sigmoid Neoplasms; Tegafur; Uracil

2005
[A case of rectal cancer treated by preoperative chemoradiation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colostomy; Drug Administration Schedule; Drug Combinations; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Preoperative Care; Rectal Neoplasms; Rectum; Remission Induction; Tegafur; Uracil

2005
[Clinical study of ambulatory patient cancer chemotherapy for advanced colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:13

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Stomatitis; Survival Rate; Tegafur; Uracil

2005
[A case of recurrent colon cancer responding completely to uracil/tegafur (UFT) plus oral leucovorin (LV) therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:13

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Lymph Node Excision; Neoplasm Recurrence, Local; Remission Induction; Tegafur; Uracil

2005
[A case of hepatic metastases of sigmoid colon cancer which completely responded to systemic l-leucovorin/5-FU therapy and oral LV/UFT combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:5

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Sigmoid Neoplasms; Tegafur; Uracil

2006
[Second-line chemotherapy with pharmacokinetic modulating chemotherapy for unresectable colorectal carcinoma recurrences resistant to 5-FU-based chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Rectal Neoplasms; Survival Rate; Tegafur; Uracil

2006
[Complete response to CPT-11 and UFT/LV combination therapy in a case with simultaneous multiple lung metastases from colon cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Irinotecan; Leucovorin; Leukopenia; Lung Neoplasms; Middle Aged; Neoplasms, Multiple Primary; Neutropenia; Remission Induction; Tegafur; Uracil; Vomiting, Anticipatory

2006
[Advanced rectal cancer in an older patient, in whom metastatic liver lesions were effectively controlled with oral UFT+LV and venous CPT-11 administration--case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colon, Sigmoid; Colostomy; Drug Administration Schedule; Drug Combinations; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Omentum; Peritoneal Neoplasms; Rectal Neoplasms; Remission Induction; Tegafur; Uracil

2006
[Retrospective analysis of tegafur/uracil (UFT) plus oral leucovorin (LV) regimen in patients with advanced colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Rectal Neoplasms; Remission Induction; Retrospective Studies; Survival Rate; Tegafur; Uracil; Vomiting, Anticipatory

2006
[24 hour infusion of CPT-11/oral UFT/LV].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Administration, Oral; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neutropenia; Tegafur; Uracil

2006
[Efficacy of uracil/tegafur (UFT) plus oral Leucovorin (LV) therapy for colorectal cancer in elderly patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Diarrhea; Drug Administration Schedule; Drug Combinations; Female; Humans; Leucovorin; Male; Middle Aged; Remission Induction; Tegafur; Uracil

2006
[Two metastatic colonic cancer patients successfully treated by combination therapy of tegafur/uracil (UFT) and oral Leucovorin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colon, Sigmoid; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Humans; Leucovorin; Lung Neoplasms; Male; Middle Aged; Remission Induction; Tegafur; Uracil

2006
[A case of advanced rectal cancer responding to oral UFT and Leucovorin-based preoperative chemoradiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Humans; Leucovorin; Male; Quality of Life; Radiotherapy Dosage; Rectal Neoplasms; Rectum; Tegafur; Uracil

2006
[A case of effective regimen of tegafur and uracil (UFT)/leucovorin (LV) plus irinotecan (CPT-11) for advanced rectal carcinoma with severe pelvic infiltration to be performed curative resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Combinations; Humans; Irinotecan; Leucovorin; Male; Neoadjuvant Therapy; Neoplasm Invasiveness; Pelvic Neoplasms; Quality of Life; Rectal Neoplasms; Tegafur; Uracil

2007
[A case of unresectable colon cancer responding to oral leucovorin+oral tegafur/uracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colon, Sigmoid; Combined Modality Therapy; Drug Administration Routes; Drug Combinations; Gastric Bypass; Hepatectomy; Humans; Jejunum; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Palliative Care; Second-Look Surgery; Sigmoid Neoplasms; Tegafur; Uracil

2007
Health-related quality of life of colorectal cancer patients receiving oral UFT plus leucovorin compared with those with surgery alone.
    International journal of clinical oncology, 2010, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Chemotherapy, Adjuvant; Chi-Square Distribution; Colectomy; Colorectal Neoplasms; Colostomy; Drug Combinations; Female; Humans; Leucovorin; Longitudinal Studies; Male; Middle Aged; Quality of Life; Surveys and Questionnaires; Tegafur; Time Factors; Treatment Outcome; Uracil

2010
[A case of effective chemotherapy using S-1 and CPT-11 following chemoradiotherapy with UFT and Leucovorin for unresectable advanced sigmoid colon cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:3

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Combinations; Humans; Irinotecan; Leucovorin; Male; Oxonic Acid; Sigmoid Neoplasms; Tegafur; Uracil

2010
Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer.
    Radiation oncology (London, England), 2010, Jun-03, Volume: 5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphocyte Count; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxonic Acid; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Survival Rate; Tegafur; Treatment Outcome; Uracil

2010