ubiquinone and ubichromenol

Topics: Alkyl and Aryl Transferases; Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Chromans; Eukaryotic Cells; Humans; Hydroxybenzoates; Methyltransferases; Mixed Function Oxygenases; Parabens; Prokaryotic Cells; Transferases; Ubiquinone; Vitamin E; Yeasts

Some peculiarities of ubiquinone (Q) biosynthesis in the livers of vitamin E-deficient rats induced in vitro by alpha-tocopherol and S-adenosylmethionine (SAM) were investigated. When [C3H3]SAM was used as a precursor, alpha-tocopherol added to the sample induced a marked elevation of the content of Q concomitantly with a drastic increase (2.82-fold) of specific radioactivity of Q in the liver as compared to control. Under identical conditions with 2-14C sodium acetate as precursor, exogenous alpha-tocopherol increased the content (by 31.4%) and specific radioactivity (by 65.2%) of Q in experimental samples, whereas the corresponding parameters of ubichromenol (QC) were essentially unchanged. SAM added to the incubation medium caused a marked increase in the content and specific radioactivity of both Q and QC as compared to control. Similar, and even more conspicuous changes were observed after combined administration of alpha-tocopherol and SAM. The role of vitamin E in the activation of methylation reactions at terminal steps of Q and QC biosynthesis in rat liver is discussed.

Topics: Animals; Chromans; Liver; Male; Rats; S-Adenosylmethionine; Ubiquinone; Vitamin E

Incubation of ground liver preparation isolated from vitamin E-deficient rats resulted in correlated in time changes of ubiquinone and ubichromenol contents and their ration in tissues. A suggestion is made on the possibility of ubiquinone and ubichromenol interconversions and of the existence of a system controlling (depending on a functional state of the organism) a certain ratio of the quinones contents in animal tissues. Possible biochemical role of ubichromenol in animals is discussed.

Topics: Animals; Benzopyrans; Chromans; Liver; Rats; Ubiquinone; Vitamin E; Vitamin E Deficiency

Topics: Carbon Isotopes; Chromans; Intestine, Small; Intestines; Kidney; Liver; Metabolism; Protein Deficiency; Rats; Research; Ubiquinone; Vitamin A Deficiency

Topics: Chemical Phenomena; Chemistry; Chromans; Light; Research; Ubiquinone

Topics: Chemical Phenomena; Chemistry; Chromans; Light; Research; Ubiquinone

Topics: Chromans; Kidney; Liver; Ubiquinone

Topics: Chromans; Humans; Ubiquinone

Topics: Animals; Brain; Chromans; Dietary Proteins; Kidney; Liver; Myocardium; Protein Deficiency; Proteins; Rats; Spleen; Tocopherols; Ubiquinone; Vitamin E

Topics: Animals; Chromans; Histocytochemistry; Horses; Myocardium; Research; Ubiquinone

Topics: Carbon Isotopes; Chromans; Chromatography; Kidney; Lactones; Liver; Metabolism; Mevalonic Acid; Rats; Research; Thyroxine; Ubiquinone

Topics: Chromans; Metabolism; Oils; Pharmacology; Rats; Research; Tocopherols; Ubiquinone; Vitamin E

Topics: Chemical Phenomena; Chemistry; Chromans; Chromatography; Chromatography, Paper; Heterocyclic Compounds; Naphthoquinones; Phenol; Phenols; Research; Tocopherols; Ubiquinone; Vitamin E; Vitamin K

Topics: Animals; Chromans; Quinones; Rats; Ubiquinone; Vitamin A; Vitamin E; Vitamin E Deficiency

Topics: Animals; Brain; Brain Diseases; Chickens; Chromans; Coenzymes; Encephalomalacia; Muscular Dystrophies; Quinones; Ubiquinone; Vitamin B 12 Deficiency; Yeasts

Topics: Candida; Chromans; Cryptococcus; Ubiquinone; Yeasts

Topics: Animals; Chromans; Quinones; Rabbits; Ubiquinone; Vitamin E

Topics: Animals; Chromans; Pantothenic Acid; Quinones; Rats; Riboflavin; Thiamine; Ubiquinone; Vitamin A; Vitamin E

Topics: Agaricales; Chromans; Quinones; Saccharomyces cerevisiae; Tocopherols; Ubiquinone; Vegetables; Vitamin E; Yeast, Dried; Yeasts

Topics: alpha-Tocopherol; Animals; Chromans; Quinones; Rats; Selenium; Selenium Compounds; Ubiquinone; Vitamin E

Topics: Chromans; Heart; Quinones; Tocopherols; Ubiquinone; Vitamin E

Topics: Chromans; Coenzymes; Diet; Liver; Nutrition Assessment; Quinones; Tretinoin; Ubiquinone; Vitamin A

Topics: Animals; Chromans; Quinones; Rats; Ubiquinone

Topics: 2,4-Dinitrophenol; Animals; Chromans; Coenzymes; Nitrophenols; Quinones; Rats; Thyroxine; Ubiquinone

Topics: Chromans; Fenfluramine; Quinones; Ubiquinone

Topics: Chromans; Quinones; Ubiquinone

Topics: Aspergillus fumigatus; Chromans; Quinones; Ubiquinone