ubiquinone and margaric-acid

ubiquinone has been researched along with margaric-acid* in 1 studies

Other Studies

1 other study(ies) available for ubiquinone and margaric-acid

ArticleYear
Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and Coenzyme Q10.
    Food chemistry, 2014, Aug-01, Volume: 156

    The influence of droplet size (d32=0.21, 0.70 or 2.2μm) and oil digestibility (corn oil versus mineral oil) on the bioavailability of a model long chain fatty acid (heptadecanoic acid) and lipophilic nutraceutical (Coenzyme Q10) was investigated using a rat feeding study. Initially, we showed that small droplets were digested more rapidly than large droplets using a simulated small intestinal model (pH stat), which was attributed to the greater surface area of lipid exposed to intestinal juices. The pH stat model also confirmed that emulsified corn oil was digestible, whereas emulsified mineral oil was indigestible. A rat feeding study showed that the bioavailability of the fatty acid and lipophilic nutraceutical in small intestinal tissues was highest when they were encapsulated within digestible oil droplets with the smallest size. This study provides important information for development of nanoemulsion-based delivery systems that increase oral bioavailability of lipophilic nutraceuticals.

    Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Corn Oil; Dietary Supplements; Drug Carriers; Emulsions; Fatty Acids; Female; Intestine, Small; Mineral Oil; Particle Size; Rats; Rats, Sprague-Dawley; Ubiquinone

2014