ubiquinone and 8-hydroxyguanine

ubiquinone has been researched along with 8-hydroxyguanine* in 1 studies

Other Studies

1 other study(ies) available for ubiquinone and 8-hydroxyguanine

Article	Year
The effect of long-term treatment with coenzyme Q10 on nucleic acid modifications by oxidation in children with Down syndrome. Neurobiology of aging, 2018, Volume: 67 Elevated levels of oxidative nucleic acid modifications have been proposed to be associated with some of the clinical characteristics of Down syndrome. Oral intake of coenzyme Q10 improves oxidative status and shows a tendency toward protective effect on DNA oxidation in certain age groups of children with Down syndrome. Here, we demonstrate that long-term (i.e., 4 years) treatment with coenzyme Q10 (ubiquinone) at the dosage of 4 mg/kg/d does not affect whole body DNA and RNA oxidation. Topics: Administration, Oral; Biomarkers; Child; Deoxyadenosines; DNA; Down Syndrome; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; RNA; Time Factors; Ubiquinone	2018

Article

Year

The effect of long-term treatment with coenzyme Q10 on nucleic acid modifications by oxidation in children with Down syndrome.

Neurobiology of aging, 2018, Volume: 67

Elevated levels of oxidative nucleic acid modifications have been proposed to be associated with some of the clinical characteristics of Down syndrome. Oral intake of coenzyme Q10 improves oxidative status and shows a tendency toward protective effect on DNA oxidation in certain age groups of children with Down syndrome. Here, we demonstrate that long-term (i.e., 4 years) treatment with coenzyme Q10 (ubiquinone) at the dosage of 4 mg/kg/d does not affect whole body DNA and RNA oxidation.

Topics: Administration, Oral; Biomarkers; Child; Deoxyadenosines; DNA; Down Syndrome; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; RNA; Time Factors; Ubiquinone

2018