ubenimex has been researched along with leukotriene b4 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Evans, JF; Kargman, S | 1 |
| Fitzpatrick, FA; Krivi, G; Orning, L | 1 |
| Haeggström, JZ; Munoz, B; Samuelsson, B; Wetterholm, A; Wong, CH; Yuan, W | 1 |
| Baker, JR; Bigby, TD; Kylstra, TA | 1 |
| Fujioka, S; Hiwada, K; Kohno, N | 1 |
| Grøn, B; Iversen, L; Kragballe, K; Kristensen, P; Ziboh, VA | 1 |
| Andberg, MB; Haeggström, JZ; Hamberg, M | 1 |
| Baset, HA; Ford-Hutchinson, AW; O'Neill, GP | 1 |
| Brock, TG; Lee, YJ; Luo, M; Marburger, TL; Maydanski, E; Paine, R; Peters-Golden, M | 1 |
| He, R; Li, B; Lv, J; Xiong, Y; Yang, W; Zhao, L; Zou, L | 1 |
| Hou, WJ; Li, LS; Li, XN; Li, YH; Liu, R; Liu, XL; Xiao, GP; Yang, Y; Ye, QY; Zhang, CR; Zhao, YH | 1 |
| Ahmadieh, H; Hafezi-Moghadam, A; Ishibashi, T; Ishikawa, K; Kanavi, MR; Koga, T; Nakama, T; Nakao, S; Ohba, M; Okuno, T; Penninger, JM; Saeki, K; Sasaki, F; Sonoda, KH; Yokomizo, T; Yoshida, S | 1 |
| Cribb, MT; Dixon, JB; Nicolls, MR; Rockson, SG; Sestito, LF; Thomas, SN | 1 |
13 other study(ies) available for ubenimex and leukotriene b4
| Article | Year |
|---|---|
Bestatin inhibits covalent coupling of [3H]LTA4 to human leukocyte LTA4 hydrolase.
Topics: Captopril; Chromatography, Gel; Epoxide Hydrolases; Humans; Leucine; Leukocytes; Leukotriene A4; Leukotriene Antagonists; Leukotriene B4; Leukotrienes | 1992 |
Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes.
Topics: Aminopeptidases; Epoxide Hydrolases; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Leucine; Leukocytes; Leukotriene B4; Metalloendopeptidases; Protease Inhibitors; Zinc | 1991 |
Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Captopril; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Ionophores; Kinetics; Leucine; Leukotriene A4; Leukotriene B4; Neutrophils; Protease Inhibitors | 1995 |
Effects of metalloproteinase inhibitors on leukotriene A4 hydrolase in human airway epithelial cells.
Topics: Aminopeptidases; Captopril; Cell Line; Cell-Free System; Epithelium; Epoxide Hydrolases; Fosinopril; Humans; Kinetics; Leucine; Leukotriene B4; Metalloendopeptidases; Neutrophils; Protease Inhibitors | 1995 |
Ubenimex activates the E-cadherin-mediated adhesion of a breast cancer cell line YMB-S.
Topics: Antibiotics, Antineoplastic; Antibodies; Breast Neoplasms; Cadherins; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Aggregation; Cell Division; Collagen; Culture Media; Drug Combinations; Humans; Immunohistochemistry; Laminin; Leucine; Leukotriene B4; Neoplasm Invasiveness; Proteoglycans; Tumor Cells, Cultured | 1995 |
Human epidermis transforms exogenous leukotriene A4 into peptide leukotrienes: possible role in transcellular metabolism.
Topics: Biotransformation; Captopril; Chromatography, High Pressure Liquid; Epidermis; Ethacrynic Acid; gamma-Glutamyltransferase; Humans; Keratinocytes; Leucine; Leukotriene A4; Leukotriene B4; Leukotriene C4; Leukotrienes; Neutrophils; Peroxidase | 1994 |
Mutation of tyrosine 383 in leukotriene A4 hydrolase allows conversion of leukotriene A4 into 5S,6S-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid. Implications for the epoxide hydrolase mechanism.
Topics: Aminopeptidases; Animals; Chromatography, High Pressure Liquid; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Leucine; Leukotriene A4; Leukotriene B4; Mass Spectrometry; Metalloproteins; Mice; Models, Chemical; Multienzyme Complexes; Mutagenesis, Site-Directed; Spectrophotometry, Ultraviolet; Tyrosine; Zinc | 1997 |
Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Arginine; Caenorhabditis elegans; Cloning, Molecular; DNA, Complementary; Epoxide Hydrolases; Evolution, Molecular; Expressed Sequence Tags; Gene Expression; Genes, Helminth; Helminth Proteins; Leucine; Leukotriene B4; Molecular Sequence Data; Physical Chromosome Mapping; Protease Inhibitors; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity | 1998 |
Nuclear localization of leukotriene A4 hydrolase in type II alveolar epithelial cells in normal and fibrotic lung.
Topics: Aminopeptidases; Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cytoplasm; Epoxide Hydrolases; Humans; Leucine; Leukotriene A4; Leukotriene B4; Male; Mice; Protease Inhibitors; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Respiratory Mucosa; Subcellular Fractions; Tissue Distribution | 2005 |
Leukotriene B₄-leukotriene B₄ receptor axis promotes oxazolone-induced contact dermatitis by directing skin homing of neutrophils and CD8⁺ T cells.
Topics: Animals; Arachidonate 5-Lipoxygenase; CD8-Positive T-Lymphocytes; Chemokine CXCL1; Chemokine CXCL2; Dermatitis, Contact; Epoxide Hydrolases; Fatty Alcohols; Female; Glycols; Inflammation; Interferon-gamma; Interleukin-1beta; Leucine; Leukotriene B4; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxazolone; Receptors, Leukotriene B4; Skin | 2015 |
[Pathogenic role of leukotriene B4 in pulmonary microvascular endothelial cell hyper- permeability induced by one lung ventilation in rabbits].
Topics: Animals; Endothelial Cells; Leucine; Leukotriene B4; Lung; One-Lung Ventilation; Permeability; Rabbits; Random Allocation | 2017 |
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models.
Topics: Animals; Benzopyrans; Carboxylic Acids; Choroidal Neovascularization; Disease Models, Animal; Eye; Eye Injuries; Hydroxyurea; Indoles; Lasers; Leucine; Leukotriene B4; Macrophages; Macular Degeneration; Male; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Leukotriene B4; Signal Transduction | 2018 |
The Kinetics of Lymphatic Dysfunction and Leukocyte Expansion in the Draining Lymph Node during LTB
Topics: Animals; Disease Models, Animal; Female; Kinetics; Leucine; Leukocytes; Leukotriene B4; Lymph Nodes; Lymphatic Vessels; Lymphedema; Male; Mice; Mice, Inbred C57BL; Protease Inhibitors | 2021 |