Compounds > ubenimex
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ubenimex and leukotriene a4

ubenimex has been researched along with leukotriene a4 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Evans, JF; Kargman, S1
Haeggström, JZ; Munoz, B; Samuelsson, B; Wetterholm, A; Wong, CH; Yuan, W1
Grøn, B; Iversen, L; Kragballe, K; Kristensen, P; Ziboh, VA1
Andberg, MB; Haeggström, JZ; Hamberg, M1
Haeggström, JZ; Nordlund, P; Thunnissen, MM1
DuBois, RN1
Beer, DG; Chen, X; Hong, J; Jiao, X; Krasna, MJ; Li, N; Wang, S; Wu, N; Yang, CS1
Brock, TG; Lee, YJ; Luo, M; Marburger, TL; Maydanski, E; Paine, R; Peters-Golden, M1

Other Studies

8 other study(ies) available for ubenimex and leukotriene a4

ArticleYear
Bestatin inhibits covalent coupling of [3H]LTA4 to human leukocyte LTA4 hydrolase.
    FEBS letters, 1992, Feb-03, Volume: 297, Issue:1-2

    Topics: Captopril; Chromatography, Gel; Epoxide Hydrolases; Humans; Leucine; Leukocytes; Leukotriene A4; Leukotriene Antagonists; Leukotriene B4; Leukotrienes

1992
Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Captopril; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Ionophores; Kinetics; Leucine; Leukotriene A4; Leukotriene B4; Neutrophils; Protease Inhibitors

1995
Human epidermis transforms exogenous leukotriene A4 into peptide leukotrienes: possible role in transcellular metabolism.
    Archives of dermatological research, 1994, Volume: 286, Issue:5

    Topics: Biotransformation; Captopril; Chromatography, High Pressure Liquid; Epidermis; Ethacrynic Acid; gamma-Glutamyltransferase; Humans; Keratinocytes; Leucine; Leukotriene A4; Leukotriene B4; Leukotriene C4; Leukotrienes; Neutrophils; Peroxidase

1994
Mutation of tyrosine 383 in leukotriene A4 hydrolase allows conversion of leukotriene A4 into 5S,6S-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid. Implications for the epoxide hydrolase mechanism.
    The Journal of biological chemistry, 1997, Sep-12, Volume: 272, Issue:37

    Topics: Aminopeptidases; Animals; Chromatography, High Pressure Liquid; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Leucine; Leukotriene A4; Leukotriene B4; Mass Spectrometry; Metalloproteins; Mice; Models, Chemical; Multienzyme Complexes; Mutagenesis, Site-Directed; Spectrophotometry, Ultraviolet; Tyrosine; Zinc

1997
Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation.
    Nature structural biology, 2001, Volume: 8, Issue:2

    Topics: Amino Acid Sequence; Aminopeptidases; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Epoxide Hydrolases; Humans; Hydrogen Bonding; Inflammation; Leucine; Leukotriene A4; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Protein Structure, Secondary; Protein Structure, Tertiary; Thermolysin; Ytterbium; Zinc

2001
Leukotriene A4 signaling, inflammation, and cancer.
    Journal of the National Cancer Institute, 2003, Jul-16, Volume: 95, Issue:14

    Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Arachidonate 5-Lipoxygenase; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Disease Models, Animal; Epoxide Hydrolases; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Leucine; Leukotriene A4; Neoplasms; Signal Transduction; Up-Regulation

2003
Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin.
    Journal of the National Cancer Institute, 2003, Jul-16, Volume: 95, Issue:14

    Topics: Adenocarcinoma; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Blotting, Western; Chemoprevention; Disease Models, Animal; Duodenum; Epoxide Hydrolases; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Incidence; Inflammation; Leucine; Leukotriene A4; Rats; Stomach; Treatment Outcome; Up-Regulation

2003
Nuclear localization of leukotriene A4 hydrolase in type II alveolar epithelial cells in normal and fibrotic lung.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 289, Issue:2

    Topics: Aminopeptidases; Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cytoplasm; Epoxide Hydrolases; Humans; Leucine; Leukotriene A4; Leukotriene B4; Male; Mice; Protease Inhibitors; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Respiratory Mucosa; Subcellular Fractions; Tissue Distribution

2005