ubenimex has been researched along with enkephalin, methionine in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (58.00) | 18.7374 |
| 1990's | 15 (30.00) | 18.2507 |
| 2000's | 5 (10.00) | 29.6817 |
| 2010's | 1 (2.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qi, HX; Wang, B; Zhang, ML; Zhang, SY; Zhang, YP | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Legrand, JC; Mauborgne, A | 1 |
| Houston, S; Le, S; Leung, MK; Stefano, GB | 1 |
| Gintzler, AR; Sublette, E | 1 |
| Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mantelet, S | 1 |
| Janković, BD; Marić, D; Pesić, G; Veljić, J | 1 |
| Ishikawa, K; Martinez, JL; Shibanoki, S; Weinberger, SB | 1 |
| Beliaev, NA; Kelesheva, LF; Kolesanova, EF; Panchenko, LF; Rotanova, TV | 1 |
| Suh, HH; Tseng, LL | 1 |
| Furuhashi, M; Kasugai, M; Kurauchi, O; Mizutani, S; Narita, O; Nomura, S; Tomoda, Y | 1 |
| Livett, BG; Marley, PD; Mitchelhill, KI | 1 |
| Ehrenpreis, S | 1 |
| Giros, B; Gros, C; Schwartz, JC; Solhonne, B | 1 |
| Bausback, HH; Ward, PE | 1 |
| Aoyagi, T; Hachisu, M; Hiranuma, T; Murata, S; Shibazaki, Y; Umezawa, H; Uotani, K | 1 |
| Costa, E; Iadarola, MJ; Mellstrom, B | 1 |
| Altiere, RJ; Crooks, PA; Gillespie, MN; Krechniak, JW; Olson, JW | 1 |
| Aoki, K; Kajiwara, M; Oka, T | 1 |
| Barchas, JD; Evans, CJ; Hurlbut, DE; Leslie, FM | 1 |
| Bourgoin, S; Cesselin, F; Dickenson, AH; Fournié-Zaluski, MC; Hamon, M; Le Bars, D; Roques, BP | 1 |
| Kubota, K; Matsuoka, Y; Satoh, S; Uruno, T | 1 |
| Krielaart, MJ; Tijms, RP; van Amsterdam, JG; van Buuren, KJ; Zuiderveld, OP | 1 |
| Busch, R; Callaghan, OH; Diamond, S; Mosnaim, AD; Puente, J; Wolf, ME | 1 |
| Kameyama, T; Katoh, A; Nabeshima, T | 1 |
| Artaud, F; Bouboutou, R; Bourgoin, S; Cesselin, F; Clot, AM; Fournie-Zaluski, MC; Hamon, M; Le Bars, D; Roques, BP | 1 |
| Han, JS; Jin, WQ; Zhou, ZF | 2 |
| Bouboutou, R; Bourgoin, S; Cesselin, F; Devin, J; Fournie-Zaluski, MC; Hamon, M; Roques, B; Waksman, G | 1 |
| Han, JS; Yuan, H | 1 |
| Gros, C; Llorens-Cortes, C; Schwartz, JC | 1 |
| Chou, J; Costa, E; Del Rio, J; Tang, J; Yang, HY | 1 |
| Corbett, AD; Kosterlitz, HW; McKnight, AT | 1 |
| Chaillet, P; Costentin, J; Coulaud, A; Fournié-Zaluski, MC; Gacel, G; Roques, BP | 1 |
| Bouboutou, R; Chaillet, P; Cherot, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Waksman, G | 1 |
| Carenzi, A; Della Bella, D; Frigeni, V; Reggiani, A | 1 |
| de la Baume, S; Giros, B; Gros, C; Schwartz, JC | 1 |
| Chaillet, P; Costentin, J; Lecomte, JM; Marçais, H; Natan, LB; Uchida, G | 1 |
| Costa, E; Yang, HY; Zhang, AZ | 1 |
| Amidon, GL; Langguth, P; Nadai, T; Sakane, T; Sezaki, H; Taki, Y; Yamashita, S | 1 |
| Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H | 1 |
| Fuentes, JA; Iglesias, T; Otero, MJ | 1 |
| Baronets, VIu; Beliaev, NA; Kolesanova, EF; Panchenko, LF | 1 |
| Auriola, S; Hämäläinen, KM; Ranta, VP; Urtti, A | 2 |
| Abramić, M; Balog, T; Hrsak, I; Marotti, T; Svoboda-Beusen, I | 1 |
| Bourgoin, S; Cesselin, F; Mauborgne, A; Poliénor, H; Roumy, M; Simonnet, G; Zajac, JM | 1 |
| Blisnick, T; Desor, D; Dugave, C; Hermitte, V; Messaoudi, M; Rigault, AG; Rougeon, F; Rougeot, C | 1 |
| Agu, RU; Jorissen, M; Kinget, R; Verbeke, N; Vu Dang, H | 1 |
| Dang, VC; Williams, JT | 1 |
| Fournie-Zaluski, MC; Gore, C; Labuz, D; Machelska, H; Roques, BP; Schreiter, A; Stein, C | 1 |
50 other study(ies) available for ubenimex and enkephalin, methionine
| Article | Year |
|---|---|
[Effect of injection of enkephalin and bestatin in caudate-putamen on operant conditioning in rats].
Topics: Animals; Avoidance Learning; Caudate Nucleus; Conditioning, Operant; Enkephalin, Methionine; Female; Leucine; Microinjections; Motor Activity; Putamen; Rats; Rats, Wistar; Reaction Time | 1992 |
Opioid control of the in vitro release of cholecystokinin-like material from the rat substantia nigra.
Topics: Animals; Calcium; Cholecystokinin; Endorphins; Enkephalin, Methionine; In Vitro Techniques; Leucine; Ligands; Male; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid; Substantia Nigra; Thiorphan | 1992 |
Degradation of Met-enkephalin by hemolymph peptidases in Mytilus edulis.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Bivalvia; Carboxypeptidases; Cell Membrane; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Glycopeptides; Hemocytes; Hemolymph; Leucine; Membrane Proteins; Molecular Sequence Data; Neprilysin; Peptidyl-Dipeptidase A; Substrate Specificity | 1992 |
Stimulus frequency and intensity: critical determinants of opioid enhancement or inhibition of evoked methionine-enkephalin release.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Captopril; Cyclic AMP; Dipeptides; Electric Stimulation; Enkephalin, Methionine; Guinea Pigs; In Vitro Techniques; Leucine; Muscle, Smooth; Myenteric Plexus; Protease Inhibitors; Pyrrolidines; Thiorphan | 1992 |
Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.
Topics: Animals; Calcitonin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Feedback; Indoles; Injections, Spinal; Leucine; Male; Morphinans; Naloxone; Naltrexone; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan | 1992 |
Enkephalinase-inhibitors modulate immune responses.
Topics: Adjuvants, Immunologic; Animals; Dipeptides; Enkephalin, Methionine; Erythrocytes; Hemagglutination Tests; Hydroxamic Acids; Injections, Intraperitoneal; Injections, Intraventricular; Leucine; Male; Neprilysin; Rats; Rats, Inbred Strains; Sheep | 1991 |
HPLC-ECD determination of the enzymatic hydrolysis of [leu]- and [met]enkephalin in rat plasma.
Topics: Acetylcholinesterase; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Leucine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Thiorphan; Tyrosine | 1990 |
[The effect of the aminopeptidase inhibitor bestatin on the enkephalin level in the rat brain].
Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Dimethyl Sulfoxide; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Leucine; Male; Rats | 1990 |
Intrathecal administration of thiorphan and bestatin enhances the antinociception and release of Met-enkephalin induced by beta-endorphin intraventricularly in anesthetized rats.
Topics: Aminopeptidases; Anesthesia; Animals; beta-Endorphin; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Leucine; Male; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Tail; Thiorphan | 1990 |
A comparison of the hypotensive effects of Met-enkephalin in normotensive and spontaneously hypertensive rats.
Topics: Animals; Antibiotics, Antineoplastic; Blood Pressure; Enkephalin, Methionine; Hypertension; Leucine; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1989 |
Effects of opioid peptides containing the sequence of Met5-enkephalin or Leu5-enkephalin on nicotine-induced secretion from bovine adrenal chromaffin cells.
Topics: Adenosine Triphosphate; Adrenal Medulla; Amino Acid Sequence; Animals; Bacitracin; Cattle; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Epinephrine; Guinea Pigs; Leucine; Nicotine; Norepinephrine; Peptide Fragments; Phenanthrolines; Rabbits; Receptors, Opioid; Thiorphan; Tiopronin | 1986 |
Pharmacology of enkephalinase inhibitors: animal and human studies.
Topics: Acupuncture Therapy; Animals; Bacitracin; beta-Endorphin; Brain; Captopril; Endorphins; Enkephalin, Methionine; Guinea Pigs; Leucine; Mice; Neprilysin; Nociceptors; Phenylalanine; Protease Inhibitors; Puromycin; Spinal Cord; Structure-Activity Relationship; Synaptic Transmission | 1985 |
Characterization of aminopeptidases responsible for inactivating endogenous (Met5)enkephalin in brain slices using peptidase inhibitors and anti-aminopeptidase M antibodies.
Topics: Aminopeptidases; Animals; Antibodies; Brain; CD13 Antigens; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enkephalin, Methionine; Globus Pallidus; Hydrolysis; In Vitro Techniques; Kinetics; Leucine; Male; Puromycin; Rats; Rats, Inbred Strains | 1986 |
Degradation of low-molecular-weight opioid peptides by vascular plasma membrane aminopeptidase M.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; CD13 Antigens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Endorphins; Enkephalin, Methionine; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Oligopeptides; Peptides; Puromycin; Swine | 1986 |
Composite effects of actinonin when inhibiting enkephalin-degrading enzymes.
Topics: Aminopeptidases; Analgesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; CD13 Antigens; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Guinea Pigs; Hydroxamic Acids; Leucine; Male; Neprilysin; Protease Inhibitors | 1987 |
Effect of peptidase inhibitors on [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8-induced antinociception.
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Drug Synergism; Enkephalin, Methionine; Leucine; Male; Pain Measurement; Protease Inhibitors; Ramipril; Rats; Rats, Inbred Strains | 1987 |
Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
Topics: Aminopeptidases; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Leucine; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
The inactivation of [Met5]-enkephalin by bestatin-sensitive aminopeptidase, captopril-sensitive peptidyl dipeptidase A and thiorphan-sensitive endopeptidase-24.11 in mouse vas deferens.
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Thiorphan; Tiopronin; Vas Deferens | 1986 |
Pharmacological properties of a proenkephalin A-derived opioid peptide: BAM 18.
Topics: Animals; Biological Assay; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Naloxone; Protein Precursors; Radioligand Assay; Receptors, Opioid; Structure-Activity Relationship | 1987 |
Increase in met-enkephalin level and antinociceptive effects induced by kelatorphan in the rat spinal cord.
Topics: Analgesics; Animals; Dipeptides; Enkephalin, Methionine; In Vitro Techniques; Leucine; Neurons; Pain; Rats; Spinal Cord; Thiorphan; Tiopronin | 1986 |
2S,3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives, enkephalinase inhibitors, augment met5-enkephalin-induced antinociception.
Topics: Analgesics; Animals; Drug Synergism; Enkephalin, Methionine; Leucine; Male; Metalloendopeptidases; Mice; Mice, Inbred Strains; Neprilysin; Pain; Phenylbutyrates; Sensory Thresholds | 1988 |
Effect of inhibitors of enkephalin degradation in the isolated guinea-pig ileum.
Topics: Animals; Buffers; Dipeptides; Enkephalin, Methionine; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Muscle Contraction; Muscle, Smooth; Neprilysin; Thiorphan | 1988 |
Studies of the in vitro human plasma degradation of methionine-enkephalin.
Topics: Chromatography, Thin Layer; Enkephalin, Methionine; Humans; Leucine; Puromycin | 1988 |
Inhibition of enkephalin degradation attenuated stress-induced motor suppression (conditioned suppression of motility).
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; Leucine; Male; Metalloendopeptidases; Mice; Motor Activity; Naloxone; Neprilysin; Pimozide; Stress, Physiological; Thiorphan; Tiopronin | 1988 |
Effects of kelatorphan and other peptidase inhibitors on the in vitro and in vivo release of methionine-enkephalin-like material from the rat spinal cord.
Topics: Animals; Dipeptides; Dose-Response Relationship, Drug; Enkephalin, Methionine; Leucine; Male; Potassium; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin | 1986 |
Electroacupuncture and morphine analgesia potentiated by bestatin and thiorphan administered to the nucleus accumbens of the rabbit.
Topics: Amino Acids, Sulfur; Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Immune Sera; Leucine; Male; Microinjections; Morphine; Naloxone; Nucleus Accumbens; Rabbits; Septal Nuclei; Thiorphan; Time Factors; Tiopronin; Transcutaneous Electric Nerve Stimulation | 1986 |
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain.
Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Corpus Striatum; Dipeptides; Enkephalin, Methionine; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Mice; Protease Inhibitors; Rats; Thiorphan; Tiopronin | 1985 |
[Electroacupuncture accelerates the biogenesis of central enkephalins in the rat].
Topics: Acupuncture Therapy; Aminopeptidases; Animals; Brain; Electric Stimulation Therapy; Enkephalin, Leucine; Enkephalin, Methionine; Female; Leucine; Male; Phenylalanine; Radioimmunoassay; Rats; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation | 1985 |
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin | 1985 |
[Inhibition of enkephalins degradation in the nucleus accumbens leads to potentiation of acupuncture and morphine analgesia].
Topics: Acupuncture Therapy; Aminopeptidases; Analgesia; Animals; Electric Stimulation Therapy; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Morphine; Neprilysin; Nucleus Accumbens; Protease Inhibitors; Rabbits; Septal Nuclei; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation | 1985 |
Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociception.
Topics: Acupuncture Therapy; Analgesia; Animals; Captopril; Electronarcosis; Enkephalin, Methionine; Leucine; Male; Perfusion; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Thiorphan; Tiopronin | 1984 |
Increase in potencies of opioid peptides after peptidase inhibition.
Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens | 1983 |
Pain control by endogenous enkephalins is mediated by mu opioid receptors.
Topics: Amino Acids, Sulfur; Analgesia; Animals; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Pain; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, mu; Thiorphan; Tiopronin | 1983 |
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.
Topics: Aminopeptidases; Analgesics; Animals; Brain; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kidney; Leucine; Neprilysin; Protease Inhibitors; Rabbits; Rats; Reaction Time; Thiorphan; Tiopronin | 1984 |
Effect of bestatin and thiorphan on [Met5]enkephalin-Arg6-Phe7-induced analgesia.
Topics: Amino Acids, Sulfur; Aminopeptidases; Analgesia; Animals; Enkephalin, Methionine; Leucine; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1984 |
[Inhibition of the evoked liberation of (Met5)enkephalin from slices of globus pallidus in the presence of thiorphan and bestatin].
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Electric Stimulation; Enkephalin, Methionine; Globus Pallidus; In Vitro Techniques; Leucine; Potassium Chloride; Protease Inhibitors; Rats; Thiorphan; Tiopronin | 1983 |
Involvement of endogenous enkephalins in the mouse 'behavioral despair' test.
Topics: Aminopeptidases; Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Motor Activity; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin | 1984 |
Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitors.
Topics: Animals; Brain; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Enkephalins; Exopeptidases; Female; Leucine; Mice; Neprilysin; Nociceptors; Protease Inhibitors; Thiorphan; Tiopronin | 1982 |
Gastrointestinal absorption of peptide drug: quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Biological Availability; Enkephalin, Methionine; Intestinal Absorption; Intestine, Small; Leucine; Male; Molecular Sequence Data; Puromycin; Rats; Rats, Wistar; Thiorphan | 1995 |
Effect of some peptidase inhibitors on exogenous and endogenous opioid actions in guinea-pig ileum.
Topics: Aminopeptidases; Animals; Bacitracin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; Leucine; Male; Morphine; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Thiorphan | 1994 |
Hypoalgesic action of bestatin analogues that inhibit central aminopeptidases, but not neutral endopeptidase.
Topics: Aminopeptidases; Analgesics; Animals; Cycloleucine; Drug Interactions; Enkephalin, Methionine; Injections, Intraventricular; Leucine; Male; Mice; Naloxone; Neprilysin; Pain Measurement; Protease Inhibitors; Thiorphan | 1993 |
[Some features of enkephalin metabolism in the rat brain after administration of bestatin].
Topics: Aminopeptidases; Animals; Brain; Carboxypeptidase H; Carboxypeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Neprilysin; Rats | 1993 |
Gradient high-performance liquid chromatographic analysis of enkephalin peptides, their metabolites, and enzyme inhibitors using combined ultraviolet and electrochemical detection II. Application to ocular permeability studies in vitro.
Topics: Aminopeptidases; Animals; Bicarbonates; Calibration; Chromatography, High Pressure Liquid; Colorimetry; Conjunctiva; Cornea; Dipeptides; Drug Combinations; Electrochemistry; Enkephalin, Methionine; Glutathione; In Vitro Techniques; Leucine; Neprilysin; Permeability; Protease Inhibitors; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Solutions; Spectrophotometry, Ultraviolet | 1998 |
The role of aminopeptidase N in Met-enkephalin modulated superoxide anion release.
Topics: Adult; Analgesics; Analgesics, Opioid; CD13 Antigens; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Leucine; Male; Neutrophils; Oligopeptides; Protease Inhibitors; Superoxides | 1999 |
Enzymatic and permeation barrier of [D-Ala(2)]-Met-enkephalinamide in the anterior membranes of the albino rabbit eye.
Topics: Aminopeptidases; Animals; Anterior Eye Segment; Conjunctiva; Cornea; Dipeptides; Enkephalin, Methionine; Female; Kinetics; Leucine; Male; Neprilysin; Permeability; Protease Inhibitors; Rabbits; Sclera | 2000 |
The neuropeptide FF analogue, 1DMe, acts as a functional opioid autoreceptor antagonist in the rat spinal cord.
Topics: Animals; Autoreceptors; Dose-Response Relationship, Drug; Enkephalin, Methionine; In Vitro Techniques; Leucine; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Potassium; Rats; Rats, Sprague-Dawley; Spinal Cord; Thiorphan | 2001 |
Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity.
Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Methionine; Formaldehyde; Glycopeptides; Kidney; Leucine; Male; Membrane Proteins; Molecular Sequence Data; Naltrexone; Neprilysin; Pain; Pain Measurement; Prostate; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Salivary Proteins and Peptides; Spinal Cord; Submandibular Gland; Substance P; Thiorphan; Wounds and Injuries | 2003 |
Metabolism and absorption enhancement of methionine enkephalin in human nasal epithelium.
Topics: Biological Transport; Cells, Cultured; Cilia; Dextrins; Enkephalin, Methionine; Glycocholic Acid; Humans; Leucine; Nasal Mucosa; Protease Inhibitors; Puromycin | 2004 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies; CD13 Antigens; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enzyme Inhibitors; Flow Cytometry; Hindlimb; Inflammation; Leucine; Leukocytes; Male; Narcotic Antagonists; Neprilysin; Neurons; Opioid Peptides; Pain; Pain Threshold; Phosphinic Acids; Rats; Rats, Wistar; Receptors, Opioid; Thiorphan | 2012 |