ubenimex has been researched along with captopril in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (44.44) | 18.7374 |
| 1990's | 21 (38.89) | 18.2507 |
| 2000's | 5 (9.26) | 29.6817 |
| 2010's | 3 (5.56) | 24.3611 |
| 2020's | 1 (1.85) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ban, M; Enomoto, H; Fujimura, K; Horiuchi, M; Miyake, Y; Mizuchi, M; Morikawa, Y; Suhara, H; Tsuji, F | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Bloecher, R; Heering, J; Kalinowsky, L; Knapp, S; Kramer, JS; Pogoryelov, D; Proschak, E; Steinhilber, D; Wittmann, SK | 1 |
| Evans, JF; Kargman, S | 1 |
| Gintzler, AR; Sublette, E | 1 |
| Fukushima, T; Sasaki, H; Sekizawa, K; Takishima, T; Yamauchi, K; Yamaya, M; Zayasu, K | 1 |
| Bachoo, M; Polosa, C; Zhang, C | 1 |
| Dion, S; Drapeau, G; Nantel, F; Regoli, D; Rhaleb, NE; Rouissi, N | 1 |
| Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K; Yamada, T | 1 |
| Chiyotani, A; Isono, K; Kanemura, T; Konno, K; Sakai, N; Takizawa, T; Tamaoki, J; Yamauchi, F | 1 |
| Fox, AJ; Morton, IK | 1 |
| Chiyotani, A; Horii, S; Isono, K; Kanemura, T; Kobayashi, K; Sakai, N; Takeuchi, S; Takizawa, T; Tamaoki, J; Yamawaki, I | 1 |
| Ishikawa, K; Martinez, JL; Shibanoki, S; Weinberger, SB | 1 |
| Ayala, JM; Molineaux, CJ | 1 |
| Giachetti, A; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Benoliel, JJ; Berthier, JL; Bourgoin, S; Cesselin, F; Hamon, M; Hirsch, M; Mauborgne, A | 1 |
| Danse, MJ; Oblin, A; Zivkovic, B | 1 |
| Rodriguez, FD; Traynor, JR; Wood, MS | 1 |
| Griesbacher, T; Hill, RG; Hughes, J; Leighton, GE | 1 |
| Rabkin, SW; Redston, M | 1 |
| Gillan, MG; Kosterlitz, HW; McKnight, AT; Robson, LE | 1 |
| Ehrenpreis, S | 1 |
| Baudry, M; Kessler, M; Lynch, G; Petersen, G; Vu, HM | 1 |
| Gibson, AM; McDermott, JR; Turner, JD | 1 |
| Altiere, RJ; Crooks, PA; Gillespie, MN; Krechniak, JW; Olson, JW | 1 |
| Aoki, K; Kajiwara, M; Oka, T | 2 |
| Basilico, L; Giagnoni, G; Gori, E; Mennuni, L; Parolaro, D; Pecora, N | 1 |
| Borson, DB; Jacoby, DB; Nadel, JA; Tamaoki, J | 1 |
| Martinez, JL; Walker, RC; Weinberger, SB; Zafuto, CE | 1 |
| Hill, RG; Hughes, J; Pittaway, KM | 1 |
| Coquerel, A; Costentin, J; Dubuc, I; Kitabgi, P; Menard, JF | 1 |
| Anadón, A; Martinez-Larrañaga, MR | 1 |
| Besselievre, R; Bouboutou, R; Devin, J; Fournie-Zaluski, MC; Roques, BP; Waksman, G | 1 |
| Gros, C; Llorens-Cortes, C; Schwartz, JC | 1 |
| Chou, J; Costa, E; Del Rio, J; Tang, J; Yang, HY | 1 |
| Corbett, AD; Kosterlitz, HW; McKnight, AT | 1 |
| Brandt, U; Lentzen, H; Palenker, J | 1 |
| Checler, F; Emson, PC; Kitabgi, P; Vincent, JP | 1 |
| Giuliani, S; Maggi, CA | 1 |
| Haeggström, JZ; Munoz, B; Samuelsson, B; Wetterholm, A; Wong, CH; Yuan, W | 1 |
| Baker, JR; Bigby, TD; Kylstra, TA | 1 |
| Drazen, JM; Lilly, CM; Martins, MA | 1 |
| Hosoki, R; Otsuka, M; Saito, K; Seno, N; Suzuki, H; Yanagisawa, M | 1 |
| Grøn, B; Iversen, L; Kragballe, K; Kristensen, P; Ziboh, VA | 1 |
| Horiguchi, Y; Ikai, K; Okano, H; Sakamoto, Y | 1 |
| Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H | 1 |
| Kokkonen, JO; Kovanen, PT; Kuoppala, A; Lindstedt, KA; Saarinen, J | 1 |
| Fagard, R; Lijnen, P; Petrov, V | 1 |
| Buljubasich, S; Lau, WA; Pennefather, JN; Ventura, S | 1 |
| Davis, TP; Nemeroff, CB; Ritchie, JC | 1 |
| Bagley, EE; Gregoriou, GC; Patel, SD; Winters, BL | 1 |
1 review(s) available for ubenimex and captopril
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
53 other study(ies) available for ubenimex and captopril
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.
Topics: Animals; Carboxylic Acids; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Epoxide Hydrolases; Humans; Inhibitory Concentration 50; Leukotriene A4; Models, Chemical; Proline; Structure-Activity Relationship; Sulfhydryl Compounds; Thiazolidines | 2008 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Thermodynamic properties of leukotriene A
Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thermodynamics | 2016 |
Bestatin inhibits covalent coupling of [3H]LTA4 to human leukocyte LTA4 hydrolase.
Topics: Captopril; Chromatography, Gel; Epoxide Hydrolases; Humans; Leucine; Leukocytes; Leukotriene A4; Leukotriene Antagonists; Leukotriene B4; Leukotrienes | 1992 |
Stimulus frequency and intensity: critical determinants of opioid enhancement or inhibition of evoked methionine-enkephalin release.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Captopril; Cyclic AMP; Dipeptides; Electric Stimulation; Enkephalin, Methionine; Guinea Pigs; In Vitro Techniques; Leucine; Muscle, Smooth; Myenteric Plexus; Protease Inhibitors; Pyrrolidines; Thiorphan | 1992 |
Opsonized zymosan decreases cytoplasmic motility of alveolar macrophages in dogs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aminopeptidases; Animals; Calcium; Captopril; Cells, Cultured; Cytoplasm; Dogs; Indomethacin; Leucine; Leupeptins; Macrophages; Phagocytosis; Pulmonary Alveoli; Superoxide Dismutase; Zymosan | 1992 |
Naloxone-sensitive inhibition of nicotinic transmission in the superior cervical ganglion of the cat.
Topics: Action Potentials; Animals; Axons; Captopril; Cats; Electric Stimulation; Female; Ganglia, Sympathetic; Hexamethonium; Hexamethonium Compounds; Leucine; Male; Naloxone; Protease Inhibitors; Receptors, Nicotinic; Synapses; Synaptic Transmission; Thiorphan | 1991 |
Inhibitors of peptidases: how they influence the biological activities of substance P, neurokinins, kinins and angiotensins in isolated vessels.
Topics: Angiotensin II; Animals; Captopril; Carotid Arteries; Dogs; Female; In Vitro Techniques; Kinins; Leucine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Portal Vein; Protease Inhibitors; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Substance P | 1990 |
Phosphoramidon potentiates mammalian tachykinin-induced biting, licking and scratching behaviour in mice.
Topics: Aggression; Animals; Behavior, Animal; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Injections, Spinal; Leucine; Male; Mice; Mice, Inbred Strains; Neurokinin A; Substance P; Tachykinins | 1990 |
Effect of neutral endopeptidase inhibition on substance-P-induced increase in short-circuit current of canine cultured tracheal epithelium.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Biological Transport, Active; Captopril; Cells, Cultured; Complement C1; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Female; Furosemide; Glycopeptides; In Vitro Techniques; Ion Channel Gating; Leucine; Leupeptins; Male; Membrane Potentials; Neprilysin; Substance P; Time Factors; Trachea | 1991 |
An examination of the proposed functional interaction of substance P and 5-HT in the guinea pig ileum.
Topics: Animals; Capsaicin; Captopril; Glycopeptides; Guinea Pigs; Ileum; Leucine; Muscle Contraction; Muscle, Smooth; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Serotonin; Substance P | 1991 |
Atrial natriuretic factor inhibits ciliary motility in cultured rabbit tracheal epithelium.
Topics: Animals; Atrial Natriuretic Factor; Captopril; Cells, Cultured; Cilia; Enzyme Inhibitors; Epithelium; Glycopeptides; Indomethacin; Kinetics; Leucine; Leupeptins; Male; Masoprocol; Methylene Blue; Movement; Piroxicam; Purinones; Rabbits; Thiorphan; Trachea | 1991 |
HPLC-ECD determination of the enzymatic hydrolysis of [leu]- and [met]enkephalin in rat plasma.
Topics: Acetylcholinesterase; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Leucine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Thiorphan; Tyrosine | 1990 |
An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins.
Topics: Animals; Brain; Captopril; Cerebral Ventricles; Choroid Plexus; Dynorphins; Enkephalin, Leucine; Kinetics; Leucine; Male; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains | 1990 |
Further studies on the response of the guinea-pig isolated bronchus to endothelins and sarafotoxin S6b.
Topics: Animals; Aorta, Thoracic; Bronchi; Captopril; Endothelins; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Leucine; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Peptides; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Viper Venoms | 1990 |
Enkephalinase is involved in the degradation of endogenous substance P released from slices of rat substantia nigra.
Topics: Animals; Captopril; Dipeptides; In Vitro Techniques; Leucine; Male; Metalloendopeptidases; Naloxone; Neprilysin; Oligopeptides; Peptidyl-Dipeptidase A; Potassium; Protease Inhibitors; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Thiorphan; Tiopronin | 1987 |
Metalloendopeptidase (EC 3.4.24.11) but not angiotensin converting enzyme is involved in the inactivation of substance P by synaptic membranes of the rat substantia nigra.
Topics: Animals; Captopril; Enzyme Activation; Glycopeptides; Hydrolysis; Leucine; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Substrate Specificity; Synaptic Membranes | 1989 |
Characterisation of kappa-opioid binding sites in rat and guinea-pig spinal cord.
Topics: Animals; Benzeneacetamides; Benzomorphans; Captopril; Diprenorphine; Dynorphins; Guinea Pigs; In Vitro Techniques; Leucine; Ligands; Male; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord | 1989 |
Reduction of food intake by central administration of cholecystokinin octapeptide in the rat is dependent upon inhibition of brain peptidases.
Topics: Animals; Brain; Captopril; Ceruletide; Eating; Injections, Intraventricular; Leucine; Male; Protease Inhibitors; Rats; Rats, Inbred Strains; Sincalide; Thiorphan | 1989 |
The effect of inhibitors of endogenous opioid degradation, bacitracin, bestatin, captopril, and D-phenylalanine, on digoxin-induced arrhythmias in guinea pigs.
Topics: Aminopeptidases; Animals; Arrhythmias, Cardiac; Bacitracin; Blood Pressure; Captopril; Digoxin; Dose-Response Relationship, Drug; Guinea Pigs; Injections, Intravenous; Leucine; Male | 1989 |
[3H]-Dynorphin A (1-8): degradation profile and binding characteristics in brain homogenates.
Topics: Animals; Brain; Captopril; Dynorphins; Guinea Pigs; Leucine; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Pharmacology of enkephalinase inhibitors: animal and human studies.
Topics: Acupuncture Therapy; Animals; Bacitracin; beta-Endorphin; Brain; Captopril; Endorphins; Enkephalin, Methionine; Guinea Pigs; Leucine; Mice; Neprilysin; Nociceptors; Phenylalanine; Protease Inhibitors; Puromycin; Spinal Cord; Structure-Activity Relationship; Synaptic Transmission | 1985 |
L-phenylalanyl-L-glutamate-stimulated, chloride-dependent glutamate binding represents glutamate sequestration mediated by an exchange system.
Topics: Aminopeptidases; Animals; Biological Transport; Brain; Captopril; Cell Membrane; Chlorides; Dipeptides; Dithionitrobenzoic Acid; Glutamates; Glutamic Acid; Hydrolysis; Kinetics; Leucine; Osmolar Concentration; Rats; Saponins | 1987 |
Involvement of endopeptidase 24.15 in the inactivation of bradykinin by rat brain slices.
Topics: 4-Aminobenzoic Acid; Animals; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Dynorphins; Endopeptidases; Glycopeptides; Hypothalamus; Leucine; Male; Metalloendopeptidases; Neurotensin; Oligopeptides; para-Aminobenzoates; Peptide Fragments; Phenanthrolines; Rats; Rats, Inbred Strains | 1987 |
Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
Topics: Aminopeptidases; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Leucine; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
The inactivation of [Met5]-enkephalin by bestatin-sensitive aminopeptidase, captopril-sensitive peptidyl dipeptidase A and thiorphan-sensitive endopeptidase-24.11 in mouse vas deferens.
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Thiorphan; Tiopronin; Vas Deferens | 1986 |
Binding studies of dermorphin and its L-form on rat brain opioid receptors.
Topics: Alanine; Animals; Binding, Competitive; Biological Assay; Brain; Captopril; Ileum; Leucine; Oligopeptides; Opioid Peptides; Rats; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship; Thiorphan; Tiopronin | 1987 |
Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase.
Topics: Animals; Captopril; Disease Models, Animal; Ferrets; In Vitro Techniques; Influenza A virus; Leucine; Leupeptins; Metalloendopeptidases; Muscle Contraction; Muscle, Smooth; Neprilysin; Orthomyxoviridae Infections; Thiorphan; Tiopronin; Trachea | 1988 |
Characterization of enkephalin degradation in rat plasma.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Enkephalins; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1986 |
Antinociceptive action of cholecystokinin octapeptide (CCK 8) and related peptides in rats and mice: effects of naloxone and peptidase inhibitors.
Topics: Animals; Captopril; FMRFamide; Gastrins; Leucine; Male; Mice; Naloxone; Neuropeptides; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Reaction Time; Sincalide; Tetragastrin; Thiorphan; Tiopronin | 1987 |
Naloxone-insensitive potentiation of neurotensin hypothermic effect by the enkephalinase inhibitor thiorphan.
Topics: Amino Acids, Sulfur; Animals; Body Temperature; Captopril; Drug Synergism; Endopeptidases; Injections, Intraventricular; Leucine; Male; Mice; Naloxone; Neprilysin; Neurotensin; Thiorphan; Tiopronin | 1986 |
An inhibitory action of tetracyclines on guinea-pig myenteric plexus.
Topics: Animals; Captopril; Drug Interactions; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Leucine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Protease Inhibitors; Tetracyclines; Thiorphan; Tiopronin | 1987 |
Binding of the bidentate inhibitor [3H]HACBO-Gly to the rat brain neutral endopeptidase "enkephalinase".
Topics: Animals; Brain; Captopril; Cell Membrane; Corpus Striatum; Glycine; Hydroxylamines; Leucine; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Substantia Nigra; Thiorphan; Tiopronin; Tissue Distribution | 1985 |
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin | 1985 |
The role of bestatin-sensitive aminopeptidase, angiotensin converting enzyme and thiorphan-sensitive "enkephalinase" in the potency of enkephalins in the guinea-pig ileum.
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1984 |
Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociception.
Topics: Acupuncture Therapy; Analgesia; Animals; Captopril; Electronarcosis; Enkephalin, Methionine; Leucine; Male; Perfusion; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Thiorphan; Tiopronin | 1984 |
Increase in potencies of opioid peptides after peptidase inhibition.
Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens | 1983 |
Enkephalin degradation by enkephalinergic neuroblastoma cells. Involvement of angiotensin-converting-enzyme.
Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Cell Membrane; Cells, Cultured; Enkephalin, Leucine; Hydrolysis; Leucine; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1984 |
Inactivation of neurotensin by rat brain synaptic membranes. Cleavage at the Pro10-Tyr11 bond by endopeptidase 24.11 (enkephalinase) and a peptidase different from proline-endopeptidase.
Topics: Animals; Captopril; Dipeptides; Endopeptidases; Hydrolysis; Leucine; Neprilysin; Neurotensin; Peptide Fragments; Peptide Hydrolases; Proline; Prolyl Oligopeptidases; Rats; Serine Endopeptidases; Synaptic Membranes; Thiorphan; Tiopronin; Tyrosine | 1984 |
A thiorphan-sensitive mechanism regulates the action of both exogenous and endogenous calcitonin gene-related peptide (CGRP) in the guinea-pig ureter.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Captopril; Electric Stimulation; Endothelins; Guinea Pigs; Humans; Leucine; Male; Muscle Contraction; Muscle, Smooth; Thiorphan; Ureter | 1994 |
Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Captopril; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Ionophores; Kinetics; Leucine; Leukotriene A4; Leukotriene B4; Neutrophils; Protease Inhibitors | 1995 |
Effects of metalloproteinase inhibitors on leukotriene A4 hydrolase in human airway epithelial cells.
Topics: Aminopeptidases; Captopril; Cell Line; Cell-Free System; Epithelium; Epoxide Hydrolases; Fosinopril; Humans; Kinetics; Leucine; Leukotriene B4; Metalloendopeptidases; Neutrophils; Protease Inhibitors | 1995 |
Peptidase modulation of vasoactive intestinal peptide pulmonary relaxation in tracheal superfused guinea pig lungs.
Topics: Animals; Aprotinin; Captopril; Dose-Response Relationship, Drug; Endopeptidases; Guinea Pigs; Leucine; Leupeptins; Lung; Male; Muscle Relaxation; Muscle, Smooth; Perfusion; Protease Inhibitors; Time Factors; Trachea; Trypsin Inhibitors; Vasoactive Intestinal Peptide | 1993 |
Potentiating effect of peptidase inhibitors on a C fiber-evoked response in the isolated spinal cord preparation of the neonatal rat.
Topics: Animals; Animals, Newborn; Captopril; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guanidines; Hydroxamic Acids; In Vitro Techniques; Kinetics; Leucine; Nerve Fibers; Neurokinin A; Protease Inhibitors; Rats; Rats, Wistar; Spinal Cord; Spinal Nerve Roots; Substance P; Tetrodotoxin; Thiorphan | 1993 |
Human epidermis transforms exogenous leukotriene A4 into peptide leukotrienes: possible role in transcellular metabolism.
Topics: Biotransformation; Captopril; Chromatography, High Pressure Liquid; Epidermis; Ethacrynic Acid; gamma-Glutamyltransferase; Humans; Keratinocytes; Leucine; Leukotriene A4; Leukotriene B4; Leukotriene C4; Leukotrienes; Neutrophils; Peroxidase | 1994 |
Leukotriene A4 hydrolase in human skin.
Topics: Blotting, Western; Captopril; Cell Line; Cell Line, Transformed; Docosahexaenoic Acids; Eicosapentaenoic Acid; Epidermal Cells; Epidermis; Epoxide Hydrolases; Fibroblasts; Humans; Immunohistochemistry; Keratinocytes; Leucine; Leukocytes, Mononuclear; Protease Inhibitors; Skin | 1994 |
Effect of some peptidase inhibitors on exogenous and endogenous opioid actions in guinea-pig ileum.
Topics: Aminopeptidases; Animals; Bacitracin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; Leucine; Male; Morphine; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Thiorphan | 1994 |
Kallidin- and bradykinin-degrading pathways in human heart: degradation of kallidin by aminopeptidase M-like activity and bradykinin by neutral endopeptidase.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Bradykinin; Captopril; CD13 Antigens; Dipeptides; Female; Glycopeptides; Heart Failure; Humans; Kallidin; Leucine; Male; Membrane Proteins; Middle Aged; Myocardium; Neprilysin; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Substrate Specificity | 1999 |
Effect of protease inhibitors on angiotensin-converting enzyme activity in human T-lymphocytes.
Topics: Adult; Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Calpain; Captopril; Cathepsins; Chymotrypsin; Cysteine Proteinase Inhibitors; Humans; Leucine; Leupeptins; Lisinopril; Lymphocyte Activation; Male; Oligopeptides; Peptidyl-Dipeptidase A; Protease Inhibitors; T-Lymphocytes | 2000 |
Calcitonin gene-related peptide (CGRP) inhibits contractions of the prostatic stroma of the rat but not the guinea-pig.
Topics: Adrenomedullin; Amyloid; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Captopril; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Glyburide; Glycopeptides; Guinea Pigs; Humans; Hypoglycemic Agents; Immunohistochemistry; Islet Amyloid Polypeptide; Leucine; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Peptides; Prostate; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects.
Topics: Adrenocorticotropic Hormone; Algorithms; Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; CD13 Antigens; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Corticotropin-Releasing Hormone; Glycopeptides; Hypothalamus; In Vitro Techniques; Kinetics; Leucine; Male; Molecular Sequence Data; Neprilysin; Peptidyl-Dipeptidase A; Pituitary Gland; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiophenes | 2003 |
Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala.
Topics: Amygdala; Animals; Captopril; Electrical Synapses; Enkephalins; Glutamic Acid; Leucine; Male; Neprilysin; Protease Inhibitors; Proteolysis; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiorphan | 2020 |