ubenimex has been researched along with actinonin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 14 (60.87) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Hashimoto, Y; Kato, F; Kato, M; Miyachi, H | 1 |
| Adhikari, N; Amin, SA; Jha, T | 1 |
| Hazato, T; Iwaguchi, T; Shimamura, M | 1 |
| Janković, BD; Marić, D; Pesić, G; Veljić, J | 1 |
| Aoyagi, T; Hachisu, M; Hiranuma, T; Murata, S; Shibazaki, Y; Umezawa, H; Uotani, K | 1 |
| Aoyagi, T; Fukuda, T; Funahashi, T; Kocha, T; Ohtsuka, E; Takeuchi, T; Wanda, T | 1 |
| Hosoki, R; Otsuka, M; Saito, K; Seno, N; Suzuki, H; Yanagisawa, M | 1 |
| Ansorge, S; Faust, J; Frank, K; Kähne, T; Lendeckel, U; Neubert, K; Reinhold, D; Wex, T | 1 |
| Fujimoto, Y; Hashimoto, Y; Kadoya, S; Kagechika, H; Kato, F; Kato, M; Koiso, Y; Komoda, M; Miyata, K; Takayama, H | 1 |
| Langner, J; Navarrete Santos, A; Riemann, D | 1 |
| Gauthier, P; Grenier, D; Mayrand, D; Nakayama, K; Plamondon, P | 1 |
| Abe, F; Fujii, H; Nishikawa, K; Sekine, K | 1 |
| Morehead, J; Morty, RE | 1 |
| Grujić, M; Renko, M | 1 |
| Griffin, JD; Ikeda, Y; Kizaki, M; Miyakawa, Y; Sawafuji, K; Weisberg, E | 1 |
| Ansorge, S; Bukowska, A; Gollnick, H; Hashimoto, Y; Lendeckel, U; Reinhold, D; Thielitz, A; Vetter, R; Wolke, C; Wrenger, S | 1 |
| Bauvois, B; Dauzonne, D | 1 |
| Bradley, JR; Cadwallader, KA; Chilvers, ER; Cowburn, AS; Deighton, J; Murray, J; Reed, BJ; Sobolewski, A | 1 |
| Ansorge, S; Bank, U; Faust, J; Gollnick, H; Hartig, R; Helmuth, M; Kähne, T; Lendeckel, U; Neubert, K; Reinhold, D; Thielitz, A; Vetter, R; Wiswedel, I; Wrenger, S; Zouboulis, CC | 1 |
| Aoyama, H; Hashimoto, Y; Miyachi, H; Naito, M; Sato, S; Sekine, K; Tetsuhashi, M | 1 |
| Krishna, S; Nampoothiri, KM; Narayanan, SS; Ramanujan, A | 1 |
2 review(s) available for ubenimex and actinonin
| Article | Year |
|---|---|
Design of Aminopeptidase N Inhibitors as Anti-cancer Agents.
Topics: Antineoplastic Agents; CD13 Antigens; Drug Design; Humans; Molecular Targeted Therapy; Protease Inhibitors | 2018 |
Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.
Topics: Animals; Betulinic Acid; CD13 Antigens; Cell Proliferation; Curcumin; Disulfides; Humans; Hydroxamic Acids; Leucine; Neovascularization, Physiologic; Neprilysin; Oligopeptides; Pentacyclic Triterpenes; Protease Inhibitors; Triterpenes; Tyrosine | 2006 |
21 other study(ies) available for ubenimex and actinonin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton.
Topics: CD13 Antigens; Enzyme Inhibitors; Humans; Phthalimides; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Enkephalin-degrading aminopeptidase in the longitudinal muscle layer of guinea pig small intestine: its properties and action on neuropeptides.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; CD13 Antigens; Guinea Pigs; Hydrolysis; Hydroxamic Acids; Ileum; Kidney; Leucine; Molecular Weight; Muscles; Neuropeptides; Oligopeptides; Peptides; Substrate Specificity | 1991 |
Enkephalinase-inhibitors modulate immune responses.
Topics: Adjuvants, Immunologic; Animals; Dipeptides; Enkephalin, Methionine; Erythrocytes; Hemagglutination Tests; Hydroxamic Acids; Injections, Intraperitoneal; Injections, Intraventricular; Leucine; Male; Neprilysin; Rats; Rats, Inbred Strains; Sheep | 1991 |
Composite effects of actinonin when inhibiting enkephalin-degrading enzymes.
Topics: Aminopeptidases; Analgesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; CD13 Antigens; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Guinea Pigs; Hydroxamic Acids; Leucine; Male; Neprilysin; Protease Inhibitors | 1987 |
Suppression of splenic enzyme activities by administration of aminopeptidase N (CD13) inhibitors: relationship between actions in vivo and in vitro.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; CD13 Antigens; Endopeptidases; Glycoside Hydrolases; Guanidines; Hydroxamic Acids; Imidazoles; Leucine; Male; Mice; Mice, Inbred BALB C; Oligopeptides; Peptides; Protease Inhibitors; Spleen | 1994 |
Potentiating effect of peptidase inhibitors on a C fiber-evoked response in the isolated spinal cord preparation of the neonatal rat.
Topics: Animals; Animals, Newborn; Captopril; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guanidines; Hydroxamic Acids; In Vitro Techniques; Kinetics; Leucine; Nerve Fibers; Neurokinin A; Protease Inhibitors; Rats; Rats, Wistar; Spinal Cord; Spinal Nerve Roots; Substance P; Tetrodotoxin; Thiorphan | 1993 |
Induction of the membrane alanyl aminopeptidase gene and surface expression in human T-cells by mitogenic activation.
Topics: CD13 Antigens; Cell Line; Cell Membrane; Cells, Cultured; DNA; Enzyme Induction; Enzyme Inhibitors; Humans; Hydroxamic Acids; Leucine; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Oligopeptides; Phytohemagglutinins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes; Tumor Cells, Cultured | 1996 |
Potent homophthalimide-type inhibitors of B16F10/L5 mouse melanoma cell invasion.
Topics: Aminopeptidases; Animals; Antineoplastic Agents; Enzyme Inhibitors; Humans; Hydroxamic Acids; Isoquinolines; Leucine; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Tumor Cells, Cultured | 1999 |
Enzymatic activity is not a precondition for the intracellular calcium increase mediated by mAbs specific for aminopeptidase N/CD13.
Topics: Antibodies, Monoclonal; Calcium; Calcium Signaling; CD13 Antigens; Humans; Hydroxamic Acids; Ion Transport; Leucine; Neoplasm Proteins; Oligopeptides; Protease Inhibitors; U937 Cells | 2000 |
Studies on the aminopeptidase activities of Porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Aminopeptidases; Anti-Bacterial Agents; Carbon Radioisotopes; Cathepsins; Chromogenic Compounds; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptidyl Peptidase 4; Gingipain Cysteine Endopeptidases; Guanidines; Hemagglutinins; Humans; Hydroxamic Acids; Leucine; Leupeptins; Mutation; Oligopeptides; Peptides; Porphyromonas gingivalis; Protease Inhibitors; Radiopharmaceuticals | 2001 |
Augmentation of death ligand-induced apoptosis by aminopeptidase inhibitors in human solid tumor cell lines.
Topics: Adenosine Triphosphate; Aminopeptidases; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Death; Cell Division; Cell-Free System; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; fas Receptor; HeLa Cells; Humans; Hydroxamic Acids; Leucine; Ligands; Puromycin; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Cloning and characterization of a leucyl aminopeptidase from three pathogenic Leishmania species.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cloning, Molecular; Guanidines; Hydroxamic Acids; Kinetics; Leishmania; Leucine; Leucyl Aminopeptidase; Molecular Sequence Data; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Protozoan | 2002 |
Aminopeptidase inhibitors bestatin and actinonin inhibit cell proliferation of myeloma cells predominantly by intracellular interactions.
Topics: Aminopeptidases; Buthionine Sulfoximine; Cell Division; Cell Membrane; Enzyme Inhibitors; Humans; Hydroxamic Acids; K562 Cells; Leucine; Multiple Myeloma; Substrate Specificity; U937 Cells | 2002 |
Aminopeptidase inhibitors inhibit proliferation and induce apoptosis of K562 and STI571-resistant K562 cell lines through the MAPK and GSK-3beta pathways.
Topics: Aminopeptidases; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Caspases; Cell Division; Cyclin D1; Drug Resistance, Neoplasm; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hydroxamic Acids; Imatinib Mesylate; K562 Cells; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitogen-Activated Protein Kinases; Phosphorylation; Piperazines; Protease Inhibitors; Pyrimidines; Serine; Signal Transduction | 2003 |
Identification of extra- and intracellular alanyl aminopeptidases as new targets to modulate keratinocyte growth and differentiation.
Topics: Animals; Base Sequence; CD13 Antigens; Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Cells, Cultured; Cytosol; DNA; Enzyme Inhibitors; Gene Expression; Humans; Hydroxamic Acids; Keratinocytes; Leucine; Male; Mice; Psoriasis; RNA, Messenger | 2004 |
Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils.
Topics: Anti-Bacterial Agents; Apoptosis; Caspase 3; Caspases; CD13 Antigens; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; In Vitro Techniques; Leucine; Neutrophils; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2006 |
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation.
Topics: Acne Vulgaris; Anti-Bacterial Agents; CD13 Antigens; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Leucine; Sebaceous Glands | 2007 |
Degradation-promoters of cellular inhibitor of apoptosis protein 1 based on bestatin and actinonin.
Topics: Apoptosis; Cell Line, Tumor; Humans; Hydroxamic Acids; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Leucine; Molecular Structure; Promoter Regions, Genetic; Structure-Activity Relationship | 2008 |
Purification and biochemical characterization of methionine aminopeptidase (MetAP) from Mycobacterium smegmatis mc2155.
Topics: Aminopeptidases; Calcium Chloride; Cobalt; Copper; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Ferrous Compounds; Hydrogen-Ion Concentration; Hydroxamic Acids; Leucine; Magnesium Chloride; Methionyl Aminopeptidases; Molecular Weight; Mycobacterium smegmatis; Peptides; Temperature | 2008 |