u 99194a and cocaine
u 99194a has been researched along with cocaine in 6 studies
Compound Research Comparison
| Studies (u 99194a) | Trials (u 99194a) | Recent Studies (post-2010) (u 99194a) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 62 | 0 | 10 | 32,461 | 1,096 | 9,400 |
Protein Interaction Comparison
| Protein | Taxonomy | u 99194a (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Baker, LE; Garner, KJ; Goodwin, AK; Svensson, KA | 1 |
| Baker, LE; Miller, ME; Svensson, KA | 1 |
| Baker, LE; Garner, KJ | 1 |
| Gál, K; Gyertyán, I | 1 |
| Anderson, SM; Pierce, RC; Schmidt, HD | 1 |
| Claytor, R; Lile, JA; Nader, MA | 1 |
Other Studies
6 other study(ies) available for u 99194a and cocaine
| Article | Year |
|---|---|
The dopamine D3 receptor antagonist PNU-99194A fails to block (+)-7-OH-DPAT substitution for D-amphetamine or cocaine.
Topics: Amphetamine; Animals; Cocaine; Discrimination, Psychological; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Indans; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Tetrahydronaphthalenes | 1998 |
Assessment of the discriminative stimulus effects of the D3 dopamine antagonist PNU-99194A in rats: comparison with psychomotor stimulants.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indans; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Stimulation, Chemical | 1997 |
Analysis of D2 and D3 receptor-selective ligands in rats trained to discriminate cocaine from saline.
Topics: Animals; Benzopyrans; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Indans; Ligands; Male; Oxazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement Schedule; Tetrahydronaphthalenes | 1999 |
Dopamine D3 receptor ligands show place conditioning effect but do not influence cocaine-induced place preference.
Topics: Animals; Avoidance Learning; Benzazepines; Benzopyrans; Cocaine; Conditioning, Classical; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Indans; Male; Naphthalenes; Nitriles; Oxazines; Piperazines; Pyrrolidines; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Spatial Behavior; Substance-Related Disorders; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2003 |
Administration of the D2 dopamine receptor antagonist sulpiride into the shell, but not the core, of the nucleus accumbens attenuates cocaine priming-induced reinstatement of drug seeking.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extinction, Psychological; Indans; Male; Microinjections; Nucleus Accumbens; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sulpiride | 2006 |
The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Food; Indans; Macaca mulatta; Male; Receptors, Dopamine D3; Reinforcement Schedule; Reinforcement, Psychology; Salicylamides; Self Administration | 2006 |