Page last updated: 2024-09-03

u 99194a and 8-hydroxy-2-(di-n-propylamino)tetralin

u 99194a has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 3 studies

Compound Research Comparison

Studies
(u 99194a)
Trials
(u 99194a)
Recent Studies (post-2010)
(u 99194a)
Studies
(8-hydroxy-2-(di-n-propylamino)tetralin)
Trials
(8-hydroxy-2-(di-n-propylamino)tetralin)
Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
620103,5307389

Protein Interaction Comparison

ProteinTaxonomyu 99194a (IC50)8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.0012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0032
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorBos taurus (cattle)0.8
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.81
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorRattus norvegicus (Norway rat)2.8959
Lysosomal alpha-glucosidaseBos taurus (cattle)0.0021

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Audinot, V; Bervoets, K; Brocco, M; Dekeyne, A; Desposte, I; Gluck, L; Gobert, A; Lejeune, F; Millan, MJ; Newman-Tancredi, A; Rivet, JM1
Annoh, N; Harano, M; Tanaka, M; Yamada, S1
Hillefors, M; von Euler, G1

Other Studies

3 other study(ies) available for u 99194a and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: 2-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Biphenyl Compounds; Body Temperature; Catalepsy; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Furans; Humans; Indans; Naphthalenes; Oxazines; Piperazines; Prolactin; Pyrrolidines; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3

1998
Dopamine D(3) receptors modulate evoked dopamine release from slices of rat nucleus accumbens via muscarinic receptors, but not from the striatum.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Haloperidol; In Vitro Techniques; Indans; Male; Muscarinic Antagonists; Neostriatum; Nucleus Accumbens; Pirenzepine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Muscarinic

1999
Pharmacology of [3H]R(+)-7-OH-DPAT binding in the rat caudate-putamen.
    Neurochemistry international, 2001, Volume: 38, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Caudate Nucleus; Clozapine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Guanidines; Guanosine Triphosphate; Haloperidol; Heterotrimeric GTP-Binding Proteins; Indans; Kinetics; Magnesium; Male; Oxazines; Protein Binding; Putamen; Quinpirole; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Remoxipride; Sodium; Specific Pathogen-Free Organisms; Sulfones; Sulpiride; Tetrahydronaphthalenes

2001