Page last updated: 2024-09-03

u 93385 and 8-hydroxy-2-(di-n-propylamino)tetralin

u 93385 has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 3 studies

*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]

*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]

Compound Research Comparison

Studies
(u 93385)
Trials
(u 93385)
Recent Studies (post-2010)
(u 93385)
Studies
(8-hydroxy-2-(di-n-propylamino)tetralin)
Trials
(8-hydroxy-2-(di-n-propylamino)tetralin)
Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
5003,5307389

Protein Interaction Comparison

ProteinTaxonomyu 93385 (IC50)8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.0012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0032
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorBos taurus (cattle)0.8
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.81
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorRattus norvegicus (Norway rat)2.8959
Lysosomal alpha-glucosidaseBos taurus (cattle)0.0021

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duncan, N; Haadsma-Svensson, SR; Lin, CH; Smith, MW; Svensson, K1
Carlsson, A; Chidester, CG; Haadsma-Svensson, SR; Lin, CH; McCall, RB; Phillips, G; Piercey, MF; Smith, MW; Svensson, K; Von Voigtlander, PF1
Clement, ME; Escandon, NA; Harris, LT; McCall, RB1

Other Studies

3 other study(ies) available for u 93385 and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
C-9 and N-substituted analogs of cis-(3aR)-(-)-2,3,3a,4,5,9b-hexahydro-3- propyl-1H-benz[e]indole-9-carboxamide: 5-HT1A receptor agonists with various degrees of metabolic stability.
    Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4

    Topics: Animals; Behavior, Animal; Cells, Cultured; Indoles; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

1995
Synthesis and biological activity of cis-(3aR)-(-)-2,3,3a,4,5,9b-hexahydro- 3-propyl-1H-benz[e]indole-9-carboxamide: a potent and selective 5-HT1A receptor agonist with good oral availability.
    Journal of medicinal chemistry, 1993, Jul-23, Volume: 36, Issue:15

    Topics: Administration, Oral; Animals; Binding Sites; Cats; Indoles; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship

1993
Tolerance development to the vagal-mediated bradycardia produced by 5-HT1A receptor agonists.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Cats; Drug Tolerance; Heart Rate; Indoles; Pyrimidines; Serotonin Receptor Agonists; Vagus Nerve

1994