Page last updated: 2024-08-24

u 77779 and cc 1065

u 77779 has been researched along with cc 1065 in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (62.50)	18.2507
2000's	3 (37.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baker, RM; Beerman, TA; Meegan, RL; Woynarowski, JM; Zsido, TJ	1
Ding, ZM; Hurley, LH	1
Gibson, NW; Lee, CS	1
Ames, MM; Reid, JM; Walker, DL	1
Han, FX; Hurley, LH	1
Koba, M; Konopa, J; Skladanowski, A	1
Lown, JW; Reddy, BS; Sharma, SK	1
Gao, X; Han, X	1

Reviews

2 review(s) available for u 77779 and cc 1065

Article	Year
Recent developments in sequence selective minor groove DNA effectors. Current medicinal chemistry, 2001, Volume: 8, Issue:5 Topics: Animals; Anthraquinones; Benzimidazoles; Bisbenzimidazole; Bleomycin; Chemistry, Pharmaceutical; Cross-Linking Reagents; Distamycins; DNA; Drug Design; Duocarmycins; Humans; Indoles; Leucomycins; Ligands; Netropsin; Urea	2001
Sequence specific recognition of ligand-DNA complexes studied by NMR. Current medicinal chemistry, 2001, Volume: 8, Issue:5 Topics: Antineoplastic Agents; Benzamidines; Binding Sites; Bleomycin; Chromomycins; DNA; DNA Adducts; Drug Design; Duocarmycins; Indoles; Intercalating Agents; Leucomycins; Ligands; Magnetic Resonance Spectroscopy; Metals; Molecular Structure; Platinum Compounds; Signal Processing, Computer-Assisted; Urea; Xanthenes; Xanthones	2001

Article

Year

Recent developments in sequence selective minor groove DNA effectors.

Current medicinal chemistry, 2001, Volume: 8, Issue:5

Topics: Animals; Anthraquinones; Benzimidazoles; Bisbenzimidazole; Bleomycin; Chemistry, Pharmaceutical; Cross-Linking Reagents; Distamycins; DNA; Drug Design; Duocarmycins; Humans; Indoles; Leucomycins; Ligands; Netropsin; Urea

2001

Sequence specific recognition of ligand-DNA complexes studied by NMR.

Current medicinal chemistry, 2001, Volume: 8, Issue:5

Topics: Antineoplastic Agents; Benzamidines; Binding Sites; Bleomycin; Chromomycins; DNA; DNA Adducts; Drug Design; Duocarmycins; Indoles; Intercalating Agents; Leucomycins; Ligands; Magnetic Resonance Spectroscopy; Metals; Molecular Structure; Platinum Compounds; Signal Processing, Computer-Assisted; Urea; Xanthenes; Xanthones

2001

Other Studies

6 other study(ies) available for u 77779 and cc 1065

Article	Year
Resistance of CHO cells expressing P-glycoprotein to cyclopropylpyrroloindole (CPI) alkylating agents. Biochemical pharmacology, 1992, Apr-15, Volume: 43, Issue:8 Topics: Alkylating Agents; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzofurans; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Drug Resistance; Duocarmycins; Indoles; Leucomycins; Membrane Glycoproteins; Urea	1992
DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065. Anti-cancer drug design, 1991, Volume: 6, Issue:5 Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Copper; Cross-Linking Reagents; DNA; DNA Damage; DNA Fingerprinting; Duocarmycins; Electrophoresis; Hydroxides; Hydroxyl Radical; Indoles; Leucomycins; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Phenanthrolines; Structure-Activity Relationship; Urea	1991
DNA damage and differential cytotoxicity produced in human carcinoma cells by CC-1065 analogues, U-73,975 and U-77,779. Cancer research, 1991, Dec-15, Volume: 51, Issue:24 Topics: Antibiotics, Antineoplastic; Benzofurans; Carcinoma; Cell Death; Colonic Neoplasms; Cross-Linking Reagents; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Dose-Response Relationship, Drug; Duocarmycins; Humans; Indoles; Leucomycins; Lung Neoplasms; Plasmids; Tumor Cells, Cultured; Urea	1991
Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065. Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:4 Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Cyclohexenes; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Urea	1994
A model for the T-antigen-induced structural alteration of the SV40 replication origin based upon experiments with specific probes for bent, straight, and unwound DNA. Biochemistry, 1996, Jun-18, Volume: 35, Issue:24 Topics: Aminoglycosides; Anti-Bacterial Agents; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Base Sequence; Binding Sites; Deoxyribonuclease I; DNA Replication; DNA, Viral; Duocarmycins; Indoles; Leucomycins; Models, Genetic; Models, Structural; Molecular Sequence Data; Oligodeoxyribonucleotides; Plasmids; Replication Origin; Restriction Mapping; Simian virus 40; Urea	1996
Does the antitumor cyclopropylpyrroloindole antibiotic CC-1065 cross-link DNA in tumor cells? Biochemical pharmacology, 2001, Jan-01, Volume: 61, Issue:1 Topics: Antibiotics, Antineoplastic; Benzofurans; Cell Division; Cross-Linking Reagents; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA; DNA, Neoplasm; Duocarmycins; HeLa Cells; Humans; Indoles; Leucomycins; Urea	2001