Page last updated: 2024-08-26

u 74389f and u 78517f

u 74389f has been researched along with u 78517f in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (84.21)18.2507
2000's3 (15.79)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Audus, KL; Cavitt, J; Shi, F1
Benedict, CR; Pakala, R1
Cross, RS; LeVine, SM; Lynch, SG; Milford, CM1
Metzinger, L; Passaquin, AC; Poindron, P; Vernier, A; Warter, JM1
Brundin, P; Duan, WM; Frodl, EM; Nakao, N; Widner, H1
Metzinger, L; Passaquin, AC; Poindron, P; Thiriet, N; Vernier, A; Warter, JM1
Brundin, P; Frodl, EM; Nakao, N1
Chan, P; Cook, D; Findlay, M; Vollrath, B1
Leclerc, L; Marden, MC; Poyart, C; Zaidi, A1
Leijendekker, WJ; Metzinger, L; Passaquin, AC; Poindron, P; Rüegg, UT1
Anderson, R; Theron, AJ1
Angeretti, N; Forloni, G; Lucca, E1
Berrino, L; Falcone, G; Filippelli, A; Filippelli, W; Mastronardi, P; Mazzarella, B; Rossi, F; Tufano, R1
Beno, DW; Kimura, RE1
Deliorman, S; Durmaz, R; Erol, K; Isiksoy, S; Tel, E; Uyar, R1
Camarasa, J; Camins, A; Comas, J; Escubedo, E; Gabriel, C; Pallàs, M; Sureda, FX1
Bernstein, C; Bernstein, H; Crowley-Weber, CL; Dvorakova, K; Garewal, H; Kunke, K; Payne, CM; Waltmire, CN; Washo-Stultz, D1
Kuo, JS; Lin, SZ; Shyu, WC; Thajeb, P1
Hugon, J; Vignes, JR1

Reviews

1 review(s) available for u 74389f and u 78517f

ArticleYear
The effect of 21-aminosteroids on endotoxin-induced TNF-alpha release.
    Critical care medicine, 1999, Volume: 27, Issue:6

    Topics: Animals; Antioxidants; Chromans; Drug Interactions; Endotoxemia; Endotoxins; Humans; Piperazines; Pregnatrienes; Tumor Necrosis Factor-alpha

1999

Other Studies

18 other study(ies) available for u 74389f and u 78517f

ArticleYear
21-aminosteroid and 2-(aminomethyl)chromans inhibition of arachidonic acid-induced lipid peroxidation and permeability enhancement in bovine brain microvessel endothelial cell monolayers.
    Free radical biology & medicine, 1995, Volume: 19, Issue:3

    Topics: Animals; Antioxidants; Arachidonic Acid; Brain; Capillary Permeability; Cattle; Cells, Cultured; Cerebrovascular Circulation; Chromans; Endothelium, Vascular; Fluorescence Polarization; Free Radical Scavengers; Lipid Peroxidation; Microcirculation; Piperazines; Pregnatrienes; Structure-Activity Relationship

1995
Novel 21-aminosteroidlike compounds prevent iron-induced free radical-mediated injury to vascular endothelial cells.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6

    Topics: Allopurinol; Animals; Antimetabolites; Antioxidants; Aorta; Butylated Hydroxytoluene; Cattle; Cell Count; Cell Membrane; Cell Survival; Chromans; Deferoxamine; Dogs; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Iron; Iron Chelating Agents; Lipid Peroxidation; Piperazines; Pregnatrienes; Probucol; Pulmonary Artery; Siderophores

1995
Testing lazaroids U-74389G and U-83836E for therapeutic value in experimental allergic encephalomyelitis in the Lewis rat.
    Research communications in molecular pathology and pharmacology, 1995, Volume: 87, Issue:3

    Topics: Animals; Antioxidants; Chromans; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Female; Free Radical Scavengers; Male; Multiple Sclerosis; Piperazines; Pregnatrienes; Rats; Rats, Inbred Lew

1995
Antioxidant lazaroids enhance differentiation of C2 skeletal muscle cells.
    Neuroscience letters, 1995, Feb-17, Volume: 186, Issue:2-3

    Topics: Actins; Animals; Antioxidants; Cell Differentiation; Cell Fusion; Chromans; Free Radical Scavengers; Mice; Microtubules; Muscle, Skeletal; Muscular Dystrophies; Piperazines; Pregnatrienes; Receptors, Nicotinic; Stimulation, Chemical

1995
Lazaroids improve the survival of grafted rat embryonic dopamine neurons.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Dec-20, Volume: 91, Issue:26

    Topics: Animals; Cell Survival; Chromans; Female; Mesencephalon; Neurons; Parkinson Disease; Piperazines; Pregnatrienes; Rats; Rats, Sprague-Dawley; Stereotyped Behavior

1994
Lazaroids enhance skeletal myogenesis in primary cultures of dystrophin-deficient mdx mice.
    Journal of the neurological sciences, 1994, Volume: 126, Issue:2

    Topics: Animals; Antioxidants; Cells, Cultured; Chromans; Cytoskeletal Proteins; Drug Interactions; Dystrophin; Methylprednisolone; Mice; Mice, Inbred mdx; Muscle Development; Muscle, Skeletal; Piperazines; Pregnatrienes; Receptors, Cholinergic

1994
Lazaroids improve the survival of cultured rat embryonic mesencephalic neurones.
    Neuroreport, 1994, Nov-21, Volume: 5, Issue:17

    Topics: Animals; Cell Count; Cell Survival; Cells, Cultured; Chromans; Fetus; Immunohistochemistry; Mesencephalon; Microscopy, Phase-Contrast; Neurons; Oxidative Stress; Piperazines; Pregnatrienes; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

1994
Lazaroids and deferoxamine attenuate the intracellular effects of oxyhaemoglobin in vascular smooth muscle.
    Cardiovascular research, 1995, Volume: 30, Issue:4

    Topics: Animals; Antioxidants; Calcium; Cell Line; Cell Survival; Chelating Agents; Chromans; Deferoxamine; Disease Models, Animal; Dogs; Female; Free Radical Scavengers; Hydrogen Peroxide; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Iron; Ischemic Attack, Transient; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxyhemoglobins; Piperazines; Pregnatrienes; Subarachnoid Hemorrhage

1995
Protection by lazaroids of the erythrocyte (Ca2+, Mg2+)-ATPase against iron-induced inhibition.
    European journal of pharmacology, 1995, Jul-18, Volume: 290, Issue:2

    Topics: Antioxidants; Ca(2+) Mg(2+)-ATPase; Chromans; Erythrocytes; Humans; In Vitro Techniques; Iron; Lipid Peroxidation; Piperazines; Pregnatrienes

1995
Modulation by prednisolone of calcium handling in skeletal muscle cells.
    British journal of pharmacology, 1995, Volume: 116, Issue:7

    Topics: Animals; Antioxidants; Calcium; Cell Differentiation; Cell Line; Chromans; Glucocorticoids; Mice; Muscle, Skeletal; Muscular Dystrophy, Animal; Piperazines; Prednisolone; Pregnatrienes

1995
Human neutrophil NADPH-oxidase activity is inhibited by lazaroids.
    Inflammation, 1996, Volume: 20, Issue:2

    Topics: Adenosine Triphosphate; Calcium; Chromans; Free Radical Scavengers; Humans; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Phospholipases A; Piperazines; Pregnatrienes; Protein Kinase C; Respiratory Burst; Superoxides

1996
Influence of cell culture conditions on the protective effect of antioxidants against beta-amyloid toxicity: studies with lazaroids.
    Brain research, 1997, Aug-01, Volume: 764, Issue:1-2

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Free Radical Scavengers; Neuroglia; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Piperazines; Pregnatrienes; Rats

1997
Cardiotoxicity of doxorubicin: effects of 21-aminosteroids.
    Life sciences, 1998, Volume: 63, Issue:17

    Topics: Animals; Antineoplastic Agents; Antioxidants; Body Weight; Chromans; Doxorubicin; Electrocardiography; Heart; Heart Diseases; Male; Piperazines; Pregnatrienes; Rats; Rats, Wistar; Survival Rate

1998
Antiproliferative properties of the lazaroids U-83836E and U-74389G on glioma cells in vitro.
    Pathology oncology research : POR, 1999, Volume: 5, Issue:3

    Topics: Animals; Antioxidants; Brain Neoplasms; Cell Division; Chromans; Dose-Response Relationship, Drug; Glioblastoma; Glioma; Humans; Inhibitory Concentration 50; Piperazines; Pregnatrienes; Rats; Tumor Cells, Cultured

1999
Evaluation of free radical production, mitochondrial membrane potential and cytoplasmic calcium in mammalian neurons by flow cytometry.
    Brain research. Brain research protocols, 1999, Volume: 4, Issue:3

    Topics: Animals; Antioxidants; Calcium; Chromans; Cytoplasm; Flow Cytometry; Fluoresceins; Free Radicals; Glutamic Acid; Ionomycin; Ionophores; Mammals; Membrane Potentials; Mitochondria; Neurons; Piperazines; Pregnatrienes; Rats; Rats, Sprague-Dawley; Staining and Labeling

1999
Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis.
    Cancer letters, 2002, Mar-28, Volume: 177, Issue:2

    Topics: Antioxidants; Apoptosis; Arachidonic Acid; Chromans; Deoxycholic Acid; Humans; Mitochondria; NADH, NADPH Oxidoreductases; Piperazines; Pregnatrienes; Reactive Oxygen Species; Succinate Dehydrogenase; Tumor Cells, Cultured

2002
Neuroprotection with methylaminochroman and lazaroid of embryonic ventral mesencephalic tegmental dopaminergic neurons in cold storage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:4

    Topics: Analysis of Variance; Animals; Cell Count; Cells, Cultured; Chromans; Coculture Techniques; Cold Temperature; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Immunohistochemistry; Neurons; Neuroprotective Agents; Piperazines; Pregnatrienes; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2006
In vitro efficacy of three lazaroids in a model of acute chemical neuronal hypoxia.
    Neuroscience letters, 2006, Oct-23, Volume: 407, Issue:2

    Topics: Animals; Cell Hypoxia; Cells, Cultured; Chromans; Colorimetry; Cyanides; Dose-Response Relationship, Drug; Female; Neurons; Neuroprotective Agents; Piperazines; Pregnancy; Pregnatrienes; Rats; Rats, Sprague-Dawley

2006