Compounds > u 74389f
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u 74389f and malondialdehyde

u 74389f has been researched along with malondialdehyde in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (77.27)18.2507
2000's1 (4.55)29.6817
2010's3 (13.64)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Altavilla, D; Ammendolia, L; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Saitta, A; Sperandeo, A; Squadrito, F; Squadrito, G1
Angel, MF; Babovic, S; Dellon, AL; Im, MJ; Manson, PN; Ress, AM1
Angel, MF; Im, MJ; Manson, PN; Shin, MS1
Brown, SA; Drake, C; Enos, LR; Harmon, FA; Henry, P; Hildebrand, SV; Magliano, D; Snyder, JR; Vatistas, NJ; Woliner, MJ1
Adams, MB; Henderson, J; Johnson, CP; Pieper, GM; Roza, AM; Van Ye, TM1
Horton, JW; White, DJ1
Altavilla, D; Avenoso, A; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Sperandeo, A; Squadrito, F; Squadrito, G1
Barry, SJ; Brown, SA; Drake, C; Enos, LR; Harmon, FA; Henry, P; Hildebrand, SV; Magliano, D; Nieto, J; Snyder, JR; Vatistas, NJ; Woliner, MJ1
Cocci, F; Ferdeghini, M; Filippi, E; Gattai, V; Miniati, M; Monti, S; Pistolesi, M; Sarnelli, R1
Ishizaki, N; Kobayashi, Y; Nemoto, A; Starzl, TE; Subbotin, V; Todo, S; Zhang, S; Zhu, Y1
Ding, Y; Gonick, HC; Ni, Z; Vaziri, ND1
Egusa, K; Haddad, J; Takoudes, TG1
Ding, Y; Oveisi, F; Vaziri, ND1
Ardanuy, C; Benasco, C; Closa, D; Cuadrado, S; de Oca, J; Hotter, G; Jaurrieta, E; Martín, E; Vallet, J1
Andrus, PK; Bassiouny, M; Hall, ED; Johns, L; Macdonald, RL; Marton, LS; Sajdak, M; Weir, BK1
Abe, T; Komatsu, K; Kuwaki, K; Sohma, H1
Egerer, K; Georgiew, A; Grune, T; Kox, WJ; Lehmann, C; Weber, M1
Adamopoulos, S; Constadinidis, T; Kyriazi, A; Lambropoulou, M; Papadopoulos, K; Papadopoulos, N; Papalois, A; Simopoulos, C; Tsaroucha, AK; Vernadakis, S1
Agrogiannis, G; Alexakis, N; Bramis, I; Chrysikos, DT; Flessas, I; Katsarou, A; Korontzi, M; Papalois, AE; Patsouri, EE; Patsouris, ES; Psaltopoulou, T; Sergentanis, TN; Zagouri, F; Zografos, GC1
Agrogiannis, G; Antoniou, E; Arkadopoulos, N; Christoloukas, N; Margonis, GA; Papalois, AE; Patsouris, ES; Pikoulis, E; Theodoropoulos, G; Zografos, GC1
Agrogiannis, G; Bramis, I; Chrysikos, D; Flessas, I; Gioxari, A; Korontzi, M; Menenakos, E; Nonni, A; Papalois, A; Patsouris, E; Toutouzas, K; Zografos, G1
Karamatsoukis, SL; Karamperi, M; Nikiteas, N; Papadopoulos, O; Papalois, AE; Patsouris, E; Pittaras, T; Stasinopoulou, M; Stavridou, A; Trigka, EA; Tsarea, K; Zacharioudaki, A; Zografos, GC1

Trials

2 trial(s) available for u 74389f and malondialdehyde

ArticleYear
Effects of the 21-aminosteroid U-74389G on ischemia and reperfusion injury of the ascending colon in horses.
    American journal of veterinary research, 1993, Volume: 54, Issue:12

    Topics: Analysis of Variance; Animals; Antioxidants; Biopsy; Colon; Female; Horse Diseases; Horses; Ischemia; Male; Malondialdehyde; Peroxidase; Pregnatrienes; Reperfusion Injury; Time Factors

1993
Effects of U-74389G, a novel 21-aminosteroid, on small intestinal ischemia and reperfusion injury in horses.
    American journal of veterinary research, 1996, Volume: 57, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Horse Diseases; Horses; Infusions, Intravenous; Intestinal Mucosa; Jejunum; Male; Malondialdehyde; Mesenteric Vascular Occlusion; Peroxidase; Pregnatrienes; Reperfusion Injury; Time Factors

1996

Other Studies

20 other study(ies) available for u 74389f and malondialdehyde

ArticleYear
Improved survival and reversal of endothelial dysfunction by the 21-aminosteroid, U-74389G in splanchnic ischaemia-reperfusion injury in the rat.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Acetylcholine; Analysis of Variance; Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Leukocyte Count; Leukopenia; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Arteries; Mesenteric Vascular Occlusion; Nitroprusside; Peroxidase; Pregnatrienes; Rats; Reperfusion Injury; Splanchnic Circulation; Steroids, Heterocyclic; Survival Rate; Tumor Necrosis Factor-alpha

1995
Free radical damage in acute nerve compression.
    Annals of plastic surgery, 1995, Volume: 34, Issue:4

    Topics: Animals; Antioxidants; Deferoxamine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Female; Free Radicals; Lipid Peroxidation; Malondialdehyde; Nerve Compression Syndromes; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sciatic Nerve

1995
Effects of 21-aminosteroid U74389F on skin-flap survival after secondary ischemia.
    Plastic and reconstructive surgery, 1994, Volume: 94, Issue:5

    Topics: Animals; Antioxidants; Lipid Peroxidation; Male; Malondialdehyde; Neutrophils; Peroxidase; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Skin; Surgical Flaps

1994
Inhibition of intestinal lipid peroxidation does not minimize morphologic damage.
    The Journal of surgical research, 1993, Volume: 55, Issue:5

    Topics: Animals; Constriction; Free Radicals; Ileum; Intestinal Mucosa; Intestines; Ischemia; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Neutrophils; Peroxidase; Pregnatrienes; Rats; Rats, Inbred Lew; Reperfusion Injury

1993
Lipid peroxidation contributes to cardiac deficits after ischemia and reperfusion of the small bowel.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 2

    Topics: Animals; Coronary Circulation; Heart; Intestine, Small; Ischemia; Lipid Peroxides; Male; Malondialdehyde; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion

1993
Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Animals; Antioxidants; Hemodynamics; Hydroxyl Radical; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Peroxidase; Pregnatrienes; Rats; Rats, Sprague-Dawley

1996
Lazaroid U-74389F attenuates phorbol ester-induced lung injury in rabbits.
    The European respiratory journal, 1996, Volume: 9, Issue:4

    Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Cell Count; Dimethyl Sulfoxide; Interleukin-8; Lung; Malondialdehyde; Neutrophils; Pregnatrienes; Proteins; Rabbits; Respiratory Distress Syndrome; Respiratory Function Tests; Tetradecanoylphorbol Acetate

1996
Comparison of various lazaroid compounds for protection against ischemic liver injury.
    Transplantation, 1997, Jan-27, Volume: 63, Issue:2

    Topics: Animals; Antioxidants; Dogs; Female; Ischemia; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Liver Function Tests; Malondialdehyde; Neovascularization, Pathologic; Pregnatrienes; Reperfusion Injury

1997
Altered nitric oxide metabolism and increased oxygen free radical activity in lead-induced hypertension: effect of lazaroid therapy.
    Kidney international, 1997, Volume: 52, Issue:4

    Topics: Animals; Antioxidants; Hypertension; Lead; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

1997
Effects of 21-aminosteroid U-74389G on acute otitis media in a guinea pig model.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1998, Volume: 118, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Ear, Middle; Free Radicals; Guinea Pigs; Lipid Peroxidation; Lipid Peroxides; Male; Malondialdehyde; Mucous Membrane; Otitis Media; Pneumococcal Infections; Pregnatrienes

1998
Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension.
    Kidney international, 1998, Volume: 53, Issue:6

    Topics: Animals; Antioxidants; Blood Pressure; Free Radical Scavengers; Hypertension; Kidney Failure, Chronic; Male; Malondialdehyde; Nitrites; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Thiourea; Uremia

1998
Protective effects of lazaroid U74389G on intestinal graft after heterotopic small bowel transplantation in rats.
    The Journal of surgical research, 1998, Feb-15, Volume: 75, Issue:1

    Topics: Animals; Antioxidants; Bacterial Translocation; Intestine, Small; Lipid Peroxidation; Male; Malondialdehyde; Peroxidase; Pregnatrienes; Rats; Rats, Inbred Lew; Xanthine Dehydrogenase; Xanthine Oxidase

1998
U74389G prevents vasospasm after subarachnoid hemorrhage in dogs.
    Neurosurgery, 1998, Volume: 42, Issue:6

    Topics: Animals; Antioxidants; Cerebral Angiography; Dogs; Hydroxybenzoates; Ischemic Attack, Transient; Malondialdehyde; Pregnatrienes; Subarachnoid Hemorrhage

1998
Lazaroid U74389G ameliorates ischemia-reperfusion injury in the rat lung transplant model.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 1999, Volume: 5, Issue:1

    Topics: Analysis of Variance; Animals; Antioxidants; Body Water; Lipid Peroxidation; Lung Transplantation; Male; Malondialdehyde; Organ Preservation; Pregnatrienes; Pulmonary Gas Exchange; Rats; Rats, Inbred Lew; Reperfusion Injury; Statistics, Nonparametric

1999
Inhibition of tumor necrosis factor-alpha release in rat experimental endotoxemia by treatment with the 21-aminosteroid U-74389G.
    Critical care medicine, 1999, Volume: 27, Issue:6

    Topics: Analysis of Variance; Animals; Antioxidants; Endotoxemia; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Escherichia coli Infections; Hemodynamics; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Pregnatrienes; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

1999
The effect of U-74389G on liver recovery after acute liver ischemia-reperfusion injury in a swine model.
    The Journal of surgical research, 2009, Volume: 151, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Hepatic Artery; Liver; Male; Malondialdehyde; Portal Vein; Pregnatrienes; Recovery of Function; Reperfusion Injury; Swine; Time Factors; Tumor Necrosis Factor-alpha

2009
The effect of U-74389G on pancreas ischemia-reperfusion injury in a swine model.
    The Journal of surgical research, 2014, Volume: 187, Issue:2

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Female; Male; Malondialdehyde; Oxidative Stress; Pancreatitis, Acute Necrotizing; Pregnatrienes; Random Allocation; Reperfusion Injury; Sus scrofa; Treatment Failure; Tumor Necrosis Factor-alpha

2014
Effectiveness of sildenafil and U-74389G in a rat model of colitis.
    The Journal of surgical research, 2015, Volume: 193, Issue:2

    Topics: Animals; Antioxidants; Colitis; Colon; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Male; Malondialdehyde; Phosphodiesterase 5 Inhibitors; Piperazines; Pregnatrienes; Purines; Random Allocation; Rats, Wistar; Sildenafil Citrate; Sulfones; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

2015
Effects of lazaroid U-74389G on intestinal ischemia and reperfusion injury in porcine experimental model.
    International journal of surgery (London, England), 2015, Volume: 13

    Topics: Animals; Antioxidants; Disease Models, Animal; Female; Male; Malondialdehyde; Models, Theoretical; Pregnatrienes; Reperfusion Injury; Swine; Tumor Necrosis Factor-alpha

2015
Beneficial Effect of U-74389 G and Sildenafil in An Experimental Model of Flap Ischemia/Reperfusion Injury in Swine. Histological and Biochemical Evaluation of the Model.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2020, Volume: 33, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Drug Synergism; Humans; Male; Malondialdehyde; Oxidative Stress; Pregnatrienes; Reperfusion Injury; Sildenafil Citrate; Superficial Back Muscles; Surgical Flaps; Swine; Tumor Necrosis Factor-alpha

2020