u 73343 has been researched along with inositol 1,4,5-trisphosphate in 14 studies
| Studies (u 73343) | Trials (u 73343) | Recent Studies (post-2010) (u 73343) | Studies (inositol 1,4,5-trisphosphate) | Trials (inositol 1,4,5-trisphosphate) | Recent Studies (post-2010) (inositol 1,4,5-trisphosphate) |
|---|---|---|---|---|---|
| 97 | 0 | 6 | 6,600 | 1 | 589 |
| Protein | Taxonomy | u 73343 (IC50) | inositol 1,4,5-trisphosphate (IC50) |
|---|---|---|---|
| Inositol-trisphosphate 3-kinase A | Rattus norvegicus (Norway rat) | 4.45 | |
| Inositol 1,4,5-trisphosphate receptor type 2 | Homo sapiens (human) | 0.03 | |
| Inositol 1,4,5-trisphosphate receptor type 3 | Homo sapiens (human) | 0.03 | |
| Inositol 1,4,5-trisphosphate receptor type 1 | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bleasdale, JE; Conn, PM; Hawes, BE; Janovick, JA; Waters, SB | 1 |
| Bozzaro, S; Malchow, D; Schaloske, R; Sordano, C | 1 |
| Alter, CA; Amagasu, M; Jolly, YC; Major, C; Shah, K; Wolf, BA | 1 |
| Fujimoto, M; Nakajima, S; Shigeri, Y | 1 |
| Berke, G; Binah, O; Felzen, B; Gardner, P | 1 |
| Idestrup, CP; Salter, MW | 1 |
| Bian, JS; Wong, TM; Xia, Q; Zhang, WM | 1 |
| Chen, TH; Cheng, H; Hsu, WH; Yibchok-Anun, S | 1 |
| Adachi, R; Hayakawa, T; Kasahara, T; Kusui, K; Matsui, S; Suzuki, K; Yamaguchi, T | 1 |
| Bayliss, DA; Lei, Q; Talley, EM | 1 |
| García, L; Guerrero-Hernández, A; Rueda, A | 1 |
| Bolton, TB; Gordienko, DV; Tsvilovskyy, VV; Tsytsyura, YD; Zholos, AV | 1 |
| Borski, RJ; Grau, EG; Hirano, T; Strom, CN; Tipsmark, CK; Weber, GM | 1 |
| Murata, Y; Nakamura, A; Nakamura, T; Ouyang, Q; Ozaki, M; Sato, H | 1 |
14 other study(ies) available for u 73343 and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production.
Topics: Animals; Calcium; Cells, Cultured; Estrenes; Female; Fura-2; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Luteinizing Hormone; Multivariate Analysis; Pituitary Gland; Pyrrolidinones; Rats; Rats, Inbred Strains; Sodium Fluoride; Time Factors; Type C Phospholipases | 1992 |
Stimulation of calcium influx by platelet activating factor in Dictyostelium.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Calcium; Cell Membrane; Cyclic AMP; Dictyostelium; Diterpenes; Dose-Response Relationship, Drug; Estrenes; Ginkgolides; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Kinetics; Lactones; Platelet Activating Factor; Pyrrolidinones; Species Specificity; Time Factors | 1995 |
U-73122 does not specifically inhibit phospholipase C in rat pancreatic islets and insulin-secreting beta-cell lines.
Topics: Animals; Cell Line; Estrenes; Glucose; Glyceraldehyde; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 1994 |
Neuropeptide YY1 receptors-mediated increase in intracellular Ca2+ concentration via phospholipase C-dependent pathway in porcine aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Benzoquinones; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Estrenes; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lactams, Macrocyclic; Muscle, Smooth, Vascular; Neuropeptide Y; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinones; Receptors, Neuropeptide Y; Rifabutin; Signal Transduction; Swine; Type C Phospholipases | 1995 |
Involvement of the IP3 cascade in the damage to guinea-pig ventricular myocytes induced by cytotoxic T lymphocytes.
Topics: Animals; Anticoagulants; Electrophysiology; Estrenes; Exudates and Transudates; Fluorescent Dyes; Fura-2; Guinea Pigs; Heart Ventricles; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred BALB C; Myocardium; Phosphodiesterase Inhibitors; Pyrrolidinones; T-Lymphocytes, Cytotoxic | 1997 |
P2Y and P2U receptors differentially release intracellular Ca2+ via the phospholipase c/inositol 1,4,5-triphosphate pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Channels; Cells, Cultured; Embryo, Mammalian; Estrenes; GTP-Binding Proteins; Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Spinal Cord; Thionucleotides; Type C Phospholipases; Uridine Triphosphate | 1998 |
Phospholipase C inhibitors attenuate arrhythmias induced by kappa-receptor stimulation in the isolated rat heart.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Arrhythmias, Cardiac; Calcium; Enzyme Inhibitors; Estrenes; Heart Rate; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Naltrexone; Narcotic Antagonists; Neomycin; Pertussis Toxin; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Signal Transduction; Streptomycin; Type C Phospholipases; Virulence Factors, Bordetella | 1998 |
Mechanisms of AVP-induced glucagon release in clonal alpha-cells in-R1-G9: involvement of Ca(2+)-dependent and -independent pathways.
Topics: Amino Acid Chloromethyl Ketones; Animals; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Clone Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Estrenes; Glucagon; Inositol 1,4,5-Trisphosphate; Nimodipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Renal Agents; Serine Proteinase Inhibitors; Thapsigargin | 2000 |
U73122 inhibits the dephosphorylation and translocation of cofilin in activated macrophage-like U937 cells.
Topics: Actin Depolymerizing Factors; Cell Membrane; Estrenes; HL-60 Cells; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Macrophage Activation; Microfilament Proteins; Opsonin Proteins; Phosphorylation; Protein Transport; Pyrrolidinones; src-Family Kinases; Superoxides; Type C Phospholipases; U937 Cells; Zymosan | 2001 |
Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.
Topics: Bacterial Proteins; Bacterial Toxins; Cell Line; Cell Membrane; Dimerization; Enzyme Inhibitors; Estrenes; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Maleimides; Membrane Potentials; Pasteurella multocida; Phorbol Esters; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Subunits; Pyrrolidinones; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Serotonin; Thyrotropin-Releasing Hormone; Transfection; Type C Phospholipases | 2001 |
Luminal Ca(2+) and the activity of sarcoplasmic reticulum Ca(2+) pumps modulate histamine-induced all-or-none Ca(2+) release in smooth muscle cells.
Topics: Acetylcholine; Animals; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Enzyme Inhibitors; Estrenes; Guinea Pigs; Histamine; Histamine Antagonists; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Muscle, Smooth; Pyrrolidinones; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Urinary Bladder | 2002 |
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Aristolochic Acids; Bridged-Ring Compounds; Caffeine; Calcium; Carbachol; Diglycerides; Estrenes; Guanosine Triphosphate; Guinea Pigs; Ileum; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoenzymes; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth; Norbornanes; Patch-Clamp Techniques; Phospholipase C beta; Phospholipases A; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ryanodine; Thiocarbamates; Thiones; Type C Phospholipases | 2004 |
Involvement of phospholipase C and intracellular calcium signaling in the gonadotropin-releasing hormone regulation of prolactin release from lactotrophs of tilapia (Oreochromis mossambicus).
Topics: Animals; Calcium; Calcium Signaling; Estrenes; Gallic Acid; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Male; Pituitary Gland; Platelet Aggregation Inhibitors; Prolactin; Pyrrolidinones; Tilapia; Type C Phospholipases | 2005 |
Contribution of the inositol 1,4,5-trisphosphate transduction cascade to the detection of "bitter" compounds in blowflies.
Topics: Animals; Diptera; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Pyrrolidinones; Sensitivity and Specificity; Signal Transduction; Taste | 2009 |