u 73122 has been researched along with u 73343 in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (36.14) | 18.2507 |
| 2000's | 49 (59.04) | 29.6817 |
| 2010's | 4 (4.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morley, P; Schwartz, JL; Tsang, BK; Vanderhyden, BC; Whitfield, JF | 1 |
| Bleasdale, JE; Conn, PM; Hawes, BE; Janovick, JA; Waters, SB | 1 |
| Fukushima, N; Misu, Y; Miyamae, T; Ueda, H; Watanabe, S | 1 |
| Brockman, JA; Hayes, SH; Lee, JS; Lowberger, LL; Silvia, WJ; Trammell, DS | 1 |
| Alter, CA; Amagasu, M; Jolly, YC; Major, C; Shah, K; Wolf, BA | 1 |
| Abayasekara, RE; Flint, AP | 1 |
| Esbenshade, TA; Minneman, KP; Theroux, TL | 1 |
| Richelson, E; Yamada, M | 1 |
| Gershengorn, MC; Heinflink, M; Nussenzveig, DR | 1 |
| Macrez-Leprêtre, N; Mironneau, J; Morel, JL | 1 |
| Fujimoto, M; Nakajima, S; Shigeri, Y | 1 |
| Wang, JP | 1 |
| Birckbichler, PJ; Chen, S; Graham, RM; Iismaa, S; Lee, KN; Lin, F | 1 |
| Fukuda, Y; Sakaki, Y; Yamashita, M | 1 |
| Hashimoto, T; Ishii, T; Ohmori, H | 1 |
| Farndale, RW; Heemskerk, JW; Sage, SO | 1 |
| Berke, G; Binah, O; Felzen, B; Gardner, P | 1 |
| Filippini, A; Palombi, F; Tripiciano, A; Ziparo, E | 1 |
| Driessens, MH; Roos, E; Soede, RD; van Hulten, PE; van Rijthoven, EA | 1 |
| Muto, Y; Nagao, T; Urushidani, T | 1 |
| Furukawa, M; Ikeda, K; Suzuki, H; Takasaka, T | 1 |
| Lou, LG; Ma, L; Pei, G; Zhang, Z | 1 |
| Bosch, RR; De Pont, JJ; Patel, AM; Smeets, RL; Van Emst-de Vries, SE; Willems, PH | 1 |
| Idestrup, CP; Salter, MW | 1 |
| Kruse, ML; Schmidt, WE; Schmidt-Choudhury, A; Schmidtmayer, J; Seebeck, J | 1 |
| Bispham, JR; Hill, SJ; Walker, EM | 1 |
| Dumont, M; Lemaire, S | 1 |
| Cenni, B; Picard, D | 1 |
| Ikenaka, K; Imoto, K; Inoue, R; Kurosaki, T; Maeda, A; Mori, Y; Okada, T; Shimizu, S; Tanaka, I; Yamakuni, T; Yamazaki, K | 1 |
| Lei, S; Lu, WY; MacDonald, JF; Orser, BA; Valenzuela, CF; Xiong, ZG | 1 |
| Lee, K; Pinnock, RD; Preston, Z; Richardson, PJ; Widdowson, L | 1 |
| Chen, TH; Cheng, H; Hsu, WH; Yibchok-Anun, S | 1 |
| Abe, K; Edagawa, Y; Saito, H | 1 |
| Bellon, G; Fawzi, A; Kefalides, NA; Monboisse, JC; Robinet, A; Ziaie, Z | 1 |
| Scofield, MA; Wangemann, P; Wonneberger, K | 1 |
| Kimura, T; Kuwabara, A; Mori, M; Ohtani, K; Okajima, F; Sato, K; Shimizu, H; Takahashi, H; Tomura, H; Tsuchiya, T | 1 |
| Aperia, A; Brismar, H; Kruse, MS; Nowicki, S | 1 |
| Chen, PC; Cheng, JT; Liu, IM; Yen, ST | 1 |
| Burt, HM; Jackon, JK; Tudan, C | 1 |
| Gibson, WJ; Hughes, SA; Young, JM | 1 |
| Adachi, R; Hayakawa, T; Kasahara, T; Kusui, K; Matsui, S; Suzuki, K; Yamaguchi, T | 1 |
| Bayliss, DA; Lei, Q; Talley, EM | 1 |
| Bates, DO; Pocock, TM | 1 |
| Chen, Y; Wu, R; Zhao, YH | 1 |
| Cheng, JT; Kuo, DH; Lin, MT; Liu, IM | 1 |
| Kato, M; Sakuma, Y; Sudo, T | 1 |
| Estacion, M; Schilling, WP | 1 |
| Hayashi, M; Hirota, N; Ichihara, A; Koura, Y; Saruta, T | 1 |
| Bell, PD; Johansson, A; Kovacs, G; Liu, R; Persson, AE; Peti-Peterdi, J | 1 |
| Cheng, H; Hsu, WH; Park, SC; Yibchok-Anun, S | 1 |
| Fukuhara, S; Inagaki, C; Oshiro, A; Otani, H; Yagi, Y | 1 |
| Abu-Basha, EA; Cheng, H; Ding, J; Hsu, WH; Ioudina, M; Yibchok-anun, S | 1 |
| Fang, Q; Kim, HJ; Kobayashi, T; Kohyama, T; Liu, X; Rennard, SI; Wen, FQ; Wyatt, TA | 1 |
| Jeffrey, JJ; Melendez, JA; Shum, JK | 1 |
| Ehrlich, K; Peskar, BA; Peskar, BM; Sawka, N | 1 |
| Masuda, T; Melis, A; Tanaka, A | 1 |
| Caprio, J; Mattson, D; Rolen, SH; Sorensen, PW | 1 |
| Ha, US; Hahn, SJ; Jo, YH; Kim, HJ; Kim, MS; Min, DS; Rhie, DJ; Sung, JH; Yoon, SH | 1 |
| Hjertos, B; Slusarski, DC; Westfall, TA | 1 |
| Horinouchi, T; Imai, T; Koike, K; Okamoto, T; Shigenobu, K; Tanaka, H; Tanaka, Y | 1 |
| Aroniadou-Anderjaska, V; Braga, MF; Hough, CJ; Li, H; Manion, ST | 1 |
| Bolton, TB; Gordienko, DV; Tsvilovskyy, VV; Tsytsyura, YD; Zholos, AV | 1 |
| Gloyna, W; Schmitz, F; Seebeck, J | 1 |
| Liu, X; Ye, K | 1 |
| Borski, RJ; Grau, EG; Hirano, T; Strom, CN; Tipsmark, CK; Weber, GM | 1 |
| Arai, J; Okada, S; Shimizu, T; Wakiguchi, H; Yamaguchi, N; Yokotani, K | 1 |
| Boon, A; Bridges, D; Deadwyler, SA; Grigorenko, E; Hampson, RE; McCloud, S; Zhuang, SY | 1 |
| Baskys, A; Bayazitov, I; Blaabjerg, M; Fang, L; Poulsen, FR; Zimmer, J | 1 |
| Campbell, WB; Edwards, EM; Falck, JR; Holmes, BB; Tang, X | 1 |
| Chang, CH; Chang, HT; Chen, WC; Chou, CT; Hsieh, CH; Hsu, SS; Jan, CR; Lin, KL; Liu, CS; Liu, SI; Wang, JL | 1 |
| Kitani, H; Ogihara, K; Sato, M; Takenouchi, T | 1 |
| Hussain, AM; Murray, AG; Zhang, QX | 1 |
| Kader, JC; Renou, JP; Ruelland, E; Taconnat, L; Vaultier, MN; Vergnolle, C; Zachowski, A | 1 |
| Applegate, MA; Estacion, M; Jones, SW; Schilling, WP; Sinkins, WG | 1 |
| Choi, SY; Chung, SC; Kim, JS; Lee, JH; Lee, S; Lee, SJ; Li, J; Oh, SB; Park, K | 1 |
| Cui, ZJ; Fang, XF; Zhou, YD | 1 |
| Eckberg, WR; Yin, X | 1 |
| Inoue, K; Kataoka, A; Koga, Y; Tozaki-Saitoh, H; Tsuda, M | 1 |
| Murata, Y; Nakamura, A; Nakamura, T; Ouyang, Q; Ozaki, M; Sato, H | 1 |
| Chávez, JC; Chirinos, M; Darszon, A; de Blas, GA; de la Vega-Beltrán, JL; González-González, ME; Larrea, F; Nishigaki, T; Solís, A; Treviño, CL | 1 |
| Choi, SY; Han, S; Jang, S; Kim, E; Kim, K; Seo, J | 1 |
| George, S; Häfner, AK; Hofmann, B; Hörnig, M; Karas, M; Maier, T; Markoutsa, S; Rödl, CB; Steinhilber, D; Werz, O; Wisniewska, JM | 1 |
| Allcock, N; Mahaut-Smith, MP; Osman, S; Rainbow, RD; Taylor, KA | 1 |
83 other study(ies) available for u 73122 and u 73343
| Article | Year |
|---|---|
A new, nongenomic estrogen action: the rapid release of intracellular calcium.
Topics: Androgens; Animals; Calcium; Cells, Cultured; Chickens; Cycloheximide; Dactinomycin; Egtazic Acid; Estrenes; Estrogens; Female; Granulosa Cells; Kinetics; Lanthanum; Neomycin; Progestins; Pyrrolidinones; Rats; Rats, Inbred Strains; Swine; Tamoxifen; Time Factors; Transcription, Genetic; Type C Phospholipases | 1992 |
Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production.
Topics: Animals; Calcium; Cells, Cultured; Estrenes; Female; Fura-2; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Luteinizing Hormone; Multivariate Analysis; Pituitary Gland; Pyrrolidinones; Rats; Rats, Inbred Strains; Sodium Fluoride; Time Factors; Type C Phospholipases | 1992 |
Evidence for a metabostatic opioid kappa-receptor inhibiting pertussis toxin-sensitive metabotropic glutamate receptor-currents in Xenopus oocytes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cell Membrane; Cerebellum; Estrenes; Female; Glutamic Acid; Guinea Pigs; Kinetics; Macromolecular Substances; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Phosphodiesterase Inhibitors; Pyrrolidines; Pyrrolidinones; Receptors, Metabotropic Glutamate; Receptors, Opioid, kappa; Recombinant Proteins; Virulence Factors, Bordetella; Xenopus laevis | 1995 |
Cellular mechanisms mediating the stimulation of ovine endometrial secretion of prostaglandin F2 alpha in response to oxytocin: role of phospholipase C and diacylglycerol.
Topics: Animals; Arginine Vasopressin; Diglycerides; Dinoprost; Endometrium; Enzyme Activation; Estrenes; Female; In Vitro Techniques; Indoles; Lactams; Lithium Chloride; Ovariectomy; Oxytocin; Pyrimidinones; Pyrrolidinones; Sheep; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiazoles; Time Factors; Type C Phospholipases | 1994 |
U-73122 does not specifically inhibit phospholipase C in rat pancreatic islets and insulin-secreting beta-cell lines.
Topics: Animals; Cell Line; Estrenes; Glucose; Glyceraldehyde; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 1994 |
A novel phospholipase C inhibitor U73122, inhibits phospholipase C-independent processes in rat luteal cells.
Topics: Animals; Bucladesine; Cells, Cultured; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Estrenes; Female; Gonadotropins, Equine; Hydroxycholesterols; Luteinizing Hormone; Pregnenolone; Progesterone; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases | 1993 |
Increased voltage-dependent calcium influx produced by alpha 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells.
Topics: Animals; Calcium; Carcinoma, Medullary; Cell Line; Estrenes; In Vitro Techniques; Inositol Phosphates; Membrane Potentials; Norepinephrine; Pyrrolidinones; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Thyroid Gland; Type C Phospholipases | 1994 |
Role of signal transduction systems in neurotensin receptor down-regulation induced by agonist in murine neuroblastoma clone N1E-115 cells.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cyclic GMP; Estrenes; In Vitro Techniques; Ionomycin; Mice; Neuroblastoma; Nitroprusside; Phosphatidylinositols; Pyrrolidinones; Receptors, Neurotensin; Second Messenger Systems; Signal Transduction; Sodium Fluoride | 1993 |
Decreased levels of internalized thyrotropin-releasing hormone receptors after uncoupling from guanine nucleotide-binding protein and phospholipase-C.
Topics: Animals; Binding Sites; Cell Line; Cell Membrane; Estrenes; GTP-Binding Proteins; Inositol Phosphates; Mice; Mutagenesis, Site-Directed; Pituitary Gland; Point Mutation; Protein Structure, Secondary; Pyrrolidinones; Receptors, Thyrotropin-Releasing Hormone; Sequence Deletion; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 1993 |
Effects of phospholipase C inhibitors on Ca2+ channel stimulation and Ca2+ release from intracellular stores evoked by alpha 1A- and alpha 2A-adrenoceptors in rat portal vein myocytes.
Topics: Animals; Bridged-Ring Compounds; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Norbornanes; Norepinephrine; Patch-Clamp Techniques; Portal Vein; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Thiocarbamates; Thiones; Type C Phospholipases | 1996 |
Neuropeptide YY1 receptors-mediated increase in intracellular Ca2+ concentration via phospholipase C-dependent pathway in porcine aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Benzoquinones; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Estrenes; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lactams, Macrocyclic; Muscle, Smooth, Vascular; Neuropeptide Y; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinones; Receptors, Neuropeptide Y; Rifabutin; Signal Transduction; Swine; Type C Phospholipases | 1995 |
U-73122, an aminosteroid phospholipase C inhibitor, may also block Ca2+ influx through phospholipase C-independent mechanism in neutrophil activation.
Topics: Animals; Calcium; Enzyme Inhibitors; Estrenes; Indoles; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 1996 |
Alpha1-adrenergic receptor signaling via Gh is subtype specific and independent of its transglutaminase activity.
Topics: Amino Acid Sequence; Animals; COS Cells; Epinephrine; Estrenes; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Inositol Phosphates; Molecular Sequence Data; Phosphodiesterase Inhibitors; Protein Glutamine gamma Glutamyltransferase 2; Pyrrolidinones; Rats; Receptors, Adrenergic, alpha-1; Signal Transduction; Transfection; Transglutaminases | 1996 |
Muscarinic and purinergic Ca2+ mobilizations in the neural retina of early embryonic chick.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Calcium; Carbachol; Chick Embryo; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Lithium; Muscarinic Agonists; Neurons; Pertussis Toxin; Phosphodiesterase Inhibitors; Purinergic Agonists; Pyrrolidinones; Receptors, Muscarinic; Receptors, Purinergic; Retina; Signal Transduction; Thapsigargin; Virulence Factors, Bordetella | 1996 |
Release of Ca2+ is the crucial step for the potentiation of IPSCs in the cultured cerebellar Purkinje cells of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Chelating Agents; Cycloleucine; Egtazic Acid; Enzyme Inhibitors; Estrenes; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Heparin; Neuroprotective Agents; Phosphodiesterase Inhibitors; Purkinje Cells; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Ruthenium Red; Synapses; Thapsigargin; Type C Phospholipases | 1996 |
Effects of U73122 and U73343 on human platelet calcium signalling and protein tyrosine phosphorylation.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Blood Proteins; Calcium; Collagen; Estrenes; Humans; Phosphodiesterase Inhibitors; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; Thapsigargin; Thrombin; Thromboxane A2; Type C Phospholipases | 1997 |
Involvement of the IP3 cascade in the damage to guinea-pig ventricular myocytes induced by cytotoxic T lymphocytes.
Topics: Animals; Anticoagulants; Electrophysiology; Estrenes; Exudates and Transudates; Fluorescent Dyes; Fura-2; Guinea Pigs; Heart Ventricles; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred BALB C; Myocardium; Phosphodiesterase Inhibitors; Pyrrolidinones; T-Lymphocytes, Cytotoxic | 1997 |
Dual control of seminiferous tubule contractility mediated by ETA and ETB endothelin receptor subtypes.
Topics: Animals; Calcium; Endothelins; Enzyme Inhibitors; Estrenes; Male; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Phosphatidylinositols; Protein Binding; Pyrrolidinones; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Seminiferous Tubules; Signal Transduction; Type C Phospholipases; Vasoconstrictor Agents | 1997 |
Activation of G-proteins with AIF-4 induces LFA-1-mediated adhesion of T-cell hybridoma cells to ICAM-1 by signal pathways that differ from phorbol ester- and manganese-induced adhesion.
Topics: Aluminum Compounds; Androstadienes; Animals; Cell Adhesion; Enzyme Activation; Enzyme Inhibitors; Estrenes; Fluorides; Genistein; GTP-Binding Proteins; Humans; Hybridomas; Indoles; Intercellular Adhesion Molecule-1; Isoflavones; Lymphocyte Function-Associated Antigen-1; Maleimides; Manganese; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Wortmannin | 1997 |
The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell.
Topics: Animals; Calcium; Estrenes; Gastric Acid; In Vitro Techniques; Parietal Cells, Gastric; Phosphodiesterase Inhibitors; Pyrrolidinones; Rabbits; Sodium-Potassium-Exchanging ATPase; Type C Phospholipases | 1997 |
P2 purinoceptor of the globular substance in the otoconial membrane of the guinea pig inner ear.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; Estrenes; Guinea Pigs; Kinetics; Otolithic Membrane; PC12 Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Rats; Receptors, Purinergic P2; Saccule and Utricle; Suramin; Triazines; Type C Phospholipases; Uridine Triphosphate | 1997 |
Nociceptin/orphanin FQ activates mitogen-activated protein kinase in Chinese hamster ovary cells expressing opioid receptor-like receptor.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Humans; Inositol Phosphates; Naloxone; Narcotic Antagonists; Nociceptin; Nociceptors; Opioid Peptides; Pertussis Toxin; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Receptors, Opioid; Type C Phospholipases; Virulence Factors, Bordetella | 1998 |
U73122 and U73343 inhibit receptor-mediated phospholipase D activation downstream of phospholipase C in CHO cells.
Topics: Animals; CHO Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Estrenes; Phospholipase D; Phospholipids; Pyrrolidinones; Receptors, Cholecystokinin; Spectrometry, Fluorescence; Type C Phospholipases | 1998 |
P2Y and P2U receptors differentially release intracellular Ca2+ via the phospholipase c/inositol 1,4,5-triphosphate pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Channels; Cells, Cultured; Embryo, Mammalian; Estrenes; GTP-Binding Proteins; Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Spinal Cord; Thionucleotides; Type C Phospholipases; Uridine Triphosphate | 1998 |
Pituitary adenylate cyclase activating polypeptide induces multiple signaling pathways in rat peritoneal mast cells.
Topics: Adenylate Cyclase Toxin; Animals; Bridged-Ring Compounds; Estrenes; Indomethacin; Masoprocol; Mast Cells; Neuropeptides; Norbornanes; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Pertussis Toxin; Phospholipid Ethers; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrrolidinones; Rats; Signal Transduction; Staurosporine; Thiocarbamates; Thiones; Virulence Factors, Bordetella | 1998 |
Nonselective effects of the putative phospholipase C inhibitor, U73122, on adenosine A1 receptor-mediated signal transduction events in Chinese hamster ovary cells.
Topics: Animals; Cell Survival; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Phosphatidylinositols; Pyrrolidinones; Receptors, Purinergic P1; Recombinant Proteins; Signal Transduction; Transfection; Type C Phospholipases; Xanthines | 1998 |
Characterization of the high affinity [3H]nociceptin binding site in membrane preparations of rat heart: correlations with the non-opioid dynorphin binding site.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Dynorphins; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Heart; Hypertension; Male; Myocardium; Neomycin; Nociceptin; Opioid Peptides; Pyrrolidinones; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomes; Time Factors | 1998 |
Two compounds commonly used for phospholipase C inhibition activate the nuclear estrogen receptors.
Topics: Cell Line; Cell Nucleus; Enzyme Inhibitors; Estradiol Congeners; Estrenes; Humans; Pyrrolidinones; Receptors, Estrogen; Transfection; Type C Phospholipases | 1999 |
Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor.
Topics: Amino Acid Sequence; Animals; Brain; Calcium; Calcium Channels; Cell Line; DNA, Complementary; Drosophila; Drosophila Proteins; Egtazic Acid; Estrenes; Gene Expression Regulation; Humans; Insect Proteins; Ion Channels; Male; Manganese; Membrane Potentials; Membrane Proteins; Mice; Molecular Sequence Data; Organ Specificity; Phosphodiesterase Inhibitors; Phylogeny; Pyrrolidinones; Recombinant Proteins; Sequence Alignment; Transcription, Genetic; Transfection; Transient Receptor Potential Channels; TRPC Cation Channels; TRPM Cation Channels | 1999 |
Platelet-derived growth factor receptor-induced feed-forward inhibition of excitatory transmission between hippocampal pyramidal neurons.
Topics: Animals; Becaplermin; Calcium; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Estrenes; Evoked Potentials; Heparin; Hippocampus; Homeostasis; In Vitro Techniques; Isoenzymes; Mice; N-Methylaspartate; Patch-Clamp Techniques; Peptide Fragments; Phospholipase C gamma; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyramidal Cells; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Platelet-Derived Growth Factor; Synaptic Transmission; Type C Phospholipases | 1999 |
Tachykinins increase [3H]acetylcholine release in mouse striatum through multiple receptor subtypes.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Choline O-Acetyltransferase; Corpus Striatum; Electrophysiology; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Antagonists; In Situ Hybridization; Indoles; Interneurons; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurokinin A; Oligopeptides; omega-N-Methylarginine; Peptide Fragments; Phenanthridines; Phosphodiesterase Inhibitors; Piperidines; Pyrrolidinones; Quinoxalines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; RNA, Messenger; Signal Transduction; Substance P; Tachykinins; Tetrodotoxin; Tritium | 2000 |
Mechanisms of AVP-induced glucagon release in clonal alpha-cells in-R1-G9: involvement of Ca(2+)-dependent and -independent pathways.
Topics: Amino Acid Chloromethyl Ketones; Animals; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Clone Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Estrenes; Glucagon; Inositol 1,4,5-Trisphosphate; Nimodipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Renal Agents; Serine Proteinase Inhibitors; Thapsigargin | 2000 |
The serotonin 5-HT2 receptor-phospholipase C system inhibits the induction of long-term potentiation in the rat visual cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Bicuculline; Electrophysiology; Estrenes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Male; Phosphodiesterase Inhibitors; Piperazines; Pyrrolidinones; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Type C Phospholipases; Visual Cortex | 2000 |
A peptide of the alpha 3(IV) chain of type IV collagen modulates stimulated neutrophil function via activation of cAMP-dependent protein kinase and Ser/Thr protein phosphatase.
Topics: Adenosine; Amino Acid Sequence; Autoantigens; Calcium; Carbazoles; Chelating Agents; Collagen; Collagen Type IV; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Antagonists; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; Indoles; Marine Toxins; Molecular Sequence Data; Neutrophils; Okadaic Acid; Oxazoles; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Pyrroles; Pyrrolidinones; Respiratory Burst; Signal Transduction; Thapsigargin; Trifluoperazine | 2000 |
Evidence for a calcium-sensing receptor in the vascular smooth muscle cells of the spiral modiolar artery.
Topics: Arteries; Base Sequence; Calcium; Calcium Channel Blockers; Cations, Divalent; Cochlea; DNA, Complementary; Enzyme Inhibitors; Estrenes; Molecular Sequence Data; Muscle, Smooth, Vascular; Nickel; Nifedipine; Pyrrolidinones; Receptors, Calcium-Sensing; Receptors, Cell Surface; Ryanodine; Thapsigargin; Type C Phospholipases; Vasodilator Agents | 2000 |
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets.
Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Cricetinae; Cyclic AMP; Estrenes; Insulin; Insulin Secretion; Islets of Langerhans; Lysophospholipids; Mice; Nifedipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Sphingosine; Type C Phospholipases | 2000 |
Dopamine-induced translocation of protein kinase C isoforms visualized in renal epithelial cells.
Topics: Animals; Benzazepines; Biological Transport; Dopamine; Dopamine Antagonists; Epithelial Cells; Estrenes; Isoenzymes; Kidney Tubules, Proximal; LLC-PK1 Cells; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyrrolidinones; Receptors, Dopamine D1; Receptors, Dopamine D2; Sodium-Potassium-Exchanging ATPase; Swine; Type C Phospholipases | 2000 |
Role of alpha1A-adrenoceptor in the regulation of glucose uptake into white adipocyte of rats in vitro.
Topics: Adipocytes; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Biological Transport, Active; Chromones; Clonidine; Deoxyglucose; Dioxanes; Enzyme Inhibitors; Estrenes; Glucose; Glucose Transporter Type 4; Indoles; Male; Maleimides; Methoxamine; Monosaccharide Transport Proteins; Morpholines; Muscle Proteins; Phenanthridines; Phosphoinositide-3 Kinase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Type C Phospholipases | 2000 |
The involvement of phospholipase C in crystal induced human neutrophil activation.
Topics: Calcium; Calcium Pyrophosphate; Cell Degranulation; Cell Respiration; Crystallization; Diglycerides; Drug Interactions; Estrenes; Humans; In Vitro Techniques; Isoenzymes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Pyrrolidinones; Signal Transduction; Superoxides; Type C Phospholipases; Uric Acid | 2000 |
The interaction of U-73122 with the histamine H1 receptor: implications for the use of U-73122 in defining H1 receptor-coupled signalling pathways.
Topics: Animals; Binding, Competitive; Estrenes; Ethylmaleimide; Guinea Pigs; Inhibitory Concentration 50; Kinetics; Male; Phosphodiesterase Inhibitors; Pyrilamine; Pyrrolidinones; Receptors, Histamine H1; Tritium; Type C Phospholipases | 2000 |
U73122 inhibits the dephosphorylation and translocation of cofilin in activated macrophage-like U937 cells.
Topics: Actin Depolymerizing Factors; Cell Membrane; Estrenes; HL-60 Cells; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Macrophage Activation; Microfilament Proteins; Opsonin Proteins; Phosphorylation; Protein Transport; Pyrrolidinones; src-Family Kinases; Superoxides; Type C Phospholipases; U937 Cells; Zymosan | 2001 |
Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.
Topics: Bacterial Proteins; Bacterial Toxins; Cell Line; Cell Membrane; Dimerization; Enzyme Inhibitors; Estrenes; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Maleimides; Membrane Potentials; Pasteurella multocida; Phorbol Esters; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Subunits; Pyrrolidinones; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Serotonin; Thyrotropin-Releasing Hormone; Transfection; Type C Phospholipases | 2001 |
In vivo mechanisms of vascular endothelial growth factor-mediated increased hydraulic conductivity of Rana capillaries.
Topics: Adenosine Triphosphate; Animals; Capillaries; Capillary Permeability; Cyclohexanones; Endothelial Growth Factors; Enzyme Inhibitors; Estrenes; Indoles; Isoenzymes; Lipoprotein Lipase; Lymphokines; Male; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Protease Inhibitors; Protein Kinase C; Pyrrolidinones; Rana temporaria; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Differential regulation of airway mucin gene expression and mucin secretion by extracellular nucleotide triphosphates.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Estrenes; Female; Gene Expression Regulation; Humans; Intubation, Intratracheal; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucin-5B; Mucins; Naphthalenes; Protein Kinase C; Pyrrolidinones; Respiratory Mucosa; Signal Transduction; Up-Regulation; Uridine Triphosphate | 2001 |
Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro.
Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; beta-Endorphin; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Male; Maleimides; Phenanthridines; Phenylephrine; Phosphodiesterase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Type C Phospholipases | 2001 |
Bradykinin and angiotensin II-induced [Ca2+]i rise in cultured rat pituitary folliculo-stellate cells.
Topics: Angiotensin II; Animals; Bradykinin; Caffeine; Calcium; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Estrenes; Galanin; Male; Neuropeptides; Neurotensin; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Pyrrolidinones; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Type C Phospholipases; Vasoconstrictor Agents | 2001 |
Blockade of maitotoxin-induced oncotic cell death reveals zeiosis.
Topics: Animals; Apoptosis; Calcium; Cattle; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Ethidium; Fluorescent Dyes; Marine Toxins; Necrosis; Oxocins; Pyrrolidinones; Type C Phospholipases | 2002 |
Phospholipase D contributes to transmural pressure control of prorenin processing in juxtaglomerular cell.
Topics: Animals; Antithrombins; Cells, Cultured; Enzyme Precursors; Estrenes; Juxtaglomerular Apparatus; Male; Phospholipase D; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sulfones; Type C Phospholipases | 2002 |
Purinergic receptor signaling at the basolateral membrane of macula densa cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzofurans; Calcium; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Fura-2; Imidazoles; Kidney Glomerulus; Microscopy, Confocal; Pyrrolidinones; Rabbits; Receptors, Purinergic; Signal Transduction; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
Somatostatin-induced paradoxical increase in intracellular Ca2+ concentration and insulin release in the presence of arginine vasopressin in clonal HIT-T15 beta-cells.
Topics: Animals; Arginine Vasopressin; Calcium; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Insulin; Islets of Langerhans; Perfusion; Pertussis Toxin; Phosphodiesterase Inhibitors; Pyrrolidinones; Signal Transduction; Somatostatin; Time Factors; Type C Phospholipases; Virulence Factors, Bordetella | 2002 |
Protease-activated receptor-2-mediated Ca2+ signaling in guinea pig tracheal epithelial cells.
Topics: Animals; Calcium Signaling; Chelating Agents; Enzyme Inhibitors; Epithelial Cells; Estrenes; Fura-2; Guinea Pigs; Manganese; Oligopeptides; Pyrrolidinones; Receptor, PAR-2; Receptors, Thrombin; Thapsigargin; Trachea; Trypsin; Type C Phospholipases | 2002 |
Mechanisms of bradykinin-induced glucagon release in clonal alpha-cells In-R1-G9: involvement of Ca(2+)-dependent and -independent pathways.
Topics: Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Clone Cells; Cricetinae; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Estrenes; Glucagon; Glucagonoma; GTP-Binding Proteins; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Mesocricetus; Microinjections; Pancreatic Neoplasms; Pertussis Toxin; Phospholipase D; Pyrrolidinones; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
PGD(2) modulates fibroblast-mediated native collagen gel contraction.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cells, Cultured; Collagen; Cyclic GMP; Enzyme Inhibitors; Estrenes; Fatty Acids, Unsaturated; Fibroblasts; Gels; Humans; Hydrazines; Indoles; Lung; Mesylates; Naphthalenes; Prostaglandin Antagonists; Prostaglandin D2; Protein Kinase C; Pyrroles; Pyrrolidinones; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Thionucleotides; Type C Phospholipases; Wound Healing; Xanthenes; Xanthones | 2002 |
Serotonin-induced MMP-13 production is mediated via phospholipase C, protein kinase C, and ERK1/2 in rat uterine smooth muscle cells.
Topics: Animals; Cells, Cultured; Collagenases; Enzyme Induction; Enzyme Inhibitors; Estrenes; Female; Isoenzymes; Kinetics; Matrix Metalloproteinase 13; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; Myometrium; Protein Kinases; Pyrrolidinones; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Type C Phospholipases | 2002 |
Role of cyclooxygenase-1 and -2, phospholipase C, and protein kinase C in prostaglandin-mediated gastroprotection.
Topics: Animals; Cromakalim; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Digestive System Physiological Phenomena; Dinoprost; Enzyme Inhibitors; Estrenes; Ethanol; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Type C Phospholipases | 2003 |
Chlorophyll antenna size adjustments by irradiance in Dunaliella salina involve coordinate regulation of chlorophyll a oxygenase (CAO) and Lhcb gene expression.
Topics: Algal Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Chlorophyll; Chlorophyta; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Oxygenases; Phosphodiesterase Inhibitors; Photosynthesis; Protein Kinase C; Pyrrolidinones; RNA Stability; RNA, Messenger; Staurosporine; Transcription, Genetic; Trifluoperazine; Type C Phospholipases | 2003 |
Polyamines as olfactory stimuli in the goldfish Carassius auratus.
Topics: Amines; Animals; Arginine; Behavior, Animal; Binding Sites; Biogenic Polyamines; Butylamines; Cadaverine; Colforsin; Electrophysiology; Estrenes; Goldfish; Odorants; Olfactory Receptor Neurons; Putrescine; Pyrrolidinones; Second Messenger Systems; Smell; Spermine | 2003 |
Endogenous somatostatin receptors mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells.
Topics: Animals; Calcium; Cell Line; Estrenes; Glioma; GTP-Binding Proteins; Image Processing, Computer-Assisted; Inosine Triphosphate; Macrocyclic Compounds; Mice; Neuroblastoma; Octreotide; Oxazoles; Pertussis Toxin; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Somatostatin; Somatostatin; Tumor Cells, Cultured; Type C Phospholipases | 2003 |
Requirement for intracellular calcium modulation in zebrafish dorsal-ventral patterning.
Topics: Animals; beta Catenin; Body Patterning; Calcium; Cytoskeletal Proteins; Diphosphonates; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Enzyme Inhibitors; Estrenes; Gene Expression Regulation, Developmental; Models, Biological; Phenotype; Phosphatidylinositols; Pyrrolidinones; Signal Transduction; Thapsigargin; Trans-Activators; Type C Phospholipases; Zebrafish; Zebrafish Proteins | 2003 |
Phospholipase C inhibitors suppress spontaneous mechanical activity of guinea pig urinary bladder smooth muscle.
Topics: Animals; Enzyme Inhibitors; Estrenes; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Type C Phospholipases; Urinary Bladder | 2003 |
Stress impairs alpha(1A) adrenoceptor-mediated noradrenergic facilitation of GABAergic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Amygdala; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Estrenes; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Morpholines; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Propranolol; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Restraint, Physical; Stress, Physiological; Tetrahydronaphthalenes; Tetrodotoxin; Time Factors | 2004 |
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Aristolochic Acids; Bridged-Ring Compounds; Caffeine; Calcium; Carbachol; Diglycerides; Estrenes; Guanosine Triphosphate; Guinea Pigs; Ileum; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoenzymes; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth; Norbornanes; Patch-Clamp Techniques; Phospholipase C beta; Phospholipases A; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ryanodine; Thiocarbamates; Thiones; Type C Phospholipases | 2004 |
Inhibition of phospholipase C-independent exocytotic responses in rat peritoneal mast cells by U73122.
Topics: Animals; Bacterial Proteins; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Estrenes; Exocytosis; Female; Guanosine 5'-O-(3-Thiotriphosphate); Inhibitory Concentration 50; Intercellular Signaling Peptides and Proteins; Male; Mast Cells; Peptides; Peritoneum; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Streptolysins; Time Factors; Type C Phospholipases; Wasp Venoms | 2005 |
Src homology domains in phospholipase C-gamma1 mediate its anti-apoptotic action through regulating the enzymatic activity.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; DNA Fragmentation; Drug Interactions; Estrenes; Indoles; Ionomycin; Ionophores; Mutagenesis; Nerve Growth Factor; PC12 Cells; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Protein Binding; Pyridines; Pyrrolidinones; Rats; src Homology Domains; Transfection; Type C Phospholipases | 2005 |
Involvement of phospholipase C and intracellular calcium signaling in the gonadotropin-releasing hormone regulation of prolactin release from lactotrophs of tilapia (Oreochromis mossambicus).
Topics: Animals; Calcium; Calcium Signaling; Estrenes; Gallic Acid; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Male; Pituitary Gland; Platelet Aggregation Inhibitors; Prolactin; Pyrrolidinones; Tilapia; Type C Phospholipases | 2005 |
Brain phospholipase C/diacylglycerol lipase are involved in bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats.
Topics: Adrenal Medulla; Animals; Arachidonic Acid; Bombesin; Brain; Cyclohexanones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Estrenes; Gastrin-Releasing Peptide; Injections, Intraventricular; Lipoprotein Lipase; Male; Neurokinin B; Norepinephrine; Peptides, Cyclic; Phospholipases A; Phospholipases A2; Pyrrolidinones; Quinacrine; Rats; Rats, Wistar; Receptors, Bombesin; Sympathetic Nervous System; Type C Phospholipases | 2005 |
Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores.
Topics: Animals; Benzoxazines; Calcium; Cell Culture Techniques; Cell Death; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclohexanols; Dantrolene; Drug Interactions; Estrenes; Fetus; Hippocampus; Macrocyclic Compounds; Morpholines; N-Methylaspartate; Naphthalenes; Neurons; Neuroprotective Agents; Okadaic Acid; Oxazoles; Piperidines; Pyrazoles; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptor, Cannabinoid, CB1; Rimonabant; Ryanodine; Thionucleotides | 2005 |
Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzoates; Cell Count; Cell Death; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Estrenes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Methoxyhydroxyphenylglycol; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Propidium; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2005 |
Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Carbamates; Cells, Cultured; Cyclohexanones; Diazomethane; Endothelium, Vascular; Estrenes; In Vitro Techniques; Indomethacin; Isoenzymes; Lipoprotein Lipase; Methacholine Chloride; Nitroarginine; Phospholipases A; Phospholipases A2; Pyrrolidinones; Rabbits; Type C Phospholipases; Vasodilation | 2006 |
Nonylphenol-induced Ca2+ elevation and Ca2+-independent cell death in human osteosarcoma cells.
Topics: Calcium; Calcium Channel Blockers; Cell Death; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Humans; Osteoblasts; Osteosarcoma; Phenols; Pyrrolidinones; Spectrometry, Fluorescence; Tetrazolium Salts; Thapsigargin; Type C Phospholipases | 2005 |
Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line.
Topics: Adenosine Triphosphate; Animals; Brain; Calcium; Calcium Signaling; Cell Line; Estrenes; Ethidium; Fluorescent Dyes; Membrane Transport Proteins; Mice; Microglia; Nuclear Pore; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Type C Phospholipases | 2005 |
Endothelial cell calpain activity facilitates lymphocyte diapedesis.
Topics: Calcium Signaling; Cell Movement; Cells, Cultured; Endothelium, Vascular; Estrenes; Humans; Lymphocytes; Pyrrolidinones; Shear Strength | 2005 |
The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
Topics: Arabidopsis; Arabidopsis Proteins; CCAAT-Binding Factor; Cells, Cultured; Cold Temperature; Diacylglycerol Kinase; Enzyme Activation; Estrenes; Gene Expression Regulation, Plant; Genes, Plant; Microarray Analysis; Multigene Family; Phospholipase D; Pyrrolidinones; Regulon; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Transcription, Genetic; Type C Phospholipases | 2005 |
Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability.
Topics: Calcium; Cell Line; Cell Membrane Permeability; Cyclohexanones; Diglycerides; Electrophysiology; Estrenes; Humans; Kidney; Membrane Potentials; Models, Biological; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium; Protease Inhibitors; Pyrrolidinones; Signal Transduction; Sodium; TRPC Cation Channels; TRPC6 Cation Channel | 2006 |
Effects of pilocarpine on the secretory acinar cells in human submandibular glands.
Topics: Adult; Aged; Aquaporin 5; Blotting, Western; Calcium; Carbachol; Dose-Response Relationship, Drug; Estrenes; Female; Humans; Ion Channels; Male; Membrane Potentials; Middle Aged; Muscarinic Agonists; Patch-Clamp Techniques; Pilocarpine; Potassium Channels; Protein Transport; Pyrrolidinones; Submandibular Gland; Type C Phospholipases | 2006 |
UVA-induced calcium oscillations in rat mast cells.
Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Catecholamines; Enzyme Activation; Estrenes; Fura-2; Imidazolines; Mast Cells; Microscopy, Confocal; NADPH Oxidases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Ultraviolet Rays | 2009 |
Characterization of phospholipases C beta and gamma and their possible roles in Chaetopterus egg activation.
Topics: Amino Acid Sequence; Animals; Estrenes; Gene Expression; Immunoblotting; Molecular Sequence Data; Oocytes; Phospholipase C beta; Phospholipase C gamma; Phylogeny; Polychaeta; Polymerase Chain Reaction; Protein Isoforms; Pyrrolidinones; Sequence Alignment | 2009 |
Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Bacterial Agents; Brain; Calcimycin; Cells, Cultured; Chemokine CCL3; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Mice; Microglia; NFATC Transcription Factors; Phosphodiesterase Inhibitors; Protein Transport; Pyrrolidinones; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Time Factors | 2009 |
Contribution of the inositol 1,4,5-trisphosphate transduction cascade to the detection of "bitter" compounds in blowflies.
Topics: Animals; Diptera; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Pyrrolidinones; Sensitivity and Specificity; Signal Transduction; Taste | 2009 |
The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: differences from the zona pellucida.
Topics: Acrosome Reaction; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Estrenes; Humans; Male; Marine Toxins; Mice; Oxocins; Pyrrolidinones; Signal Transduction; Sperm Capacitation; Spermatozoa; Type C Phospholipases; Zona Pellucida | 2011 |
Regulation of hippocampal long-term potentiation and long-term depression by diacylglycerol kinase ζ.
Topics: Animals; CA1 Region, Hippocampal; Dendritic Spines; Diacylglycerol Kinase; Diglycerides; Disks Large Homolog 4 Protein; Estrenes; Guanylate Kinases; Indoles; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Knockout; Neuronal Plasticity; Phosphatidic Acids; Protein Kinase C; Pyramidal Cells; Pyrrolidinones; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Type C Phospholipases | 2012 |
Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416.
Topics: Adult; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cysteine; Estrenes; HeLa Cells; Humans; Lipoxygenase Inhibitors; Mice; Models, Molecular; Mutant Proteins; Protein Binding; Protein Structure, Secondary; Pyrrolidinones; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds | 2012 |
Detachment of surface membrane invagination systems by cationic amphiphilic drugs.
Topics: Animals; Cell Surface Extensions; Cells, Cultured; Drug Evaluation, Preclinical; Estrenes; Male; Megakaryocytes; Myocytes, Cardiac; Phenothiazines; Pyrrolidinones; Rats, Wistar; Sulfonamides | 2016 |