u 73122 has been researched along with sphingosine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 15 (51.72) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Kondo, Y; Okajima, F | 1 |
| Essington, TE; Shayman, JA; Williams, JA; Wu, D; Yule, DI | 1 |
| Amemiya, H; Li, XK; Shinomiya, T; Suzuki, S | 1 |
| Kimura, M; Ogihara, M | 1 |
| Han, JK; Kim, MJ; Noh, SJ; Shim, S | 1 |
| Chin, TY; Chueh, SH | 2 |
| Igarashi, Y; Okajima, F; Sato, K; Tomura, H; Ui, M | 1 |
| Calcerrada, MC; Catalan, RE; Martinez, AM; Miguel, BG | 1 |
| Malaquias, AT; Oliveira, MM | 1 |
| Kimura, T; Kuwabara, A; Mori, M; Ohtani, K; Okajima, F; Sato, K; Shimizu, H; Takahashi, H; Tomura, H; Tsuchiya, T | 1 |
| Assmann, G; Fobker, M; Höbbel, G; Junker, R; Nofer, JR; Seedorf, U; Tepel, M; von Eckardstein, A; Voss, R; Walter, M; Wolinska, I; Zidek, W | 1 |
| Elsner, N; Heinrich, R; Wenzel, B | 1 |
| Fueller, M; Siess, W; Tigyi, G; Wang, DA | 1 |
| Akiyama, N; Hirabayashi, T; Murayama, T; Shimamura, K; Takashiro, Y | 1 |
| Hauser, CJ; Itagaki, K; Kannan, KB | 1 |
| Logsdon, CD; Mulholland, MW; Segura, BJ; Xiao, L; Zhang, W | 1 |
| Bae, YS; Im, DS; Jo, SH; Kim, MK; Kim, SD; Lee, HY; Park, KS; Shin, EH | 1 |
| Bae, YS; Kim, MK; Kim, YD; Lee, H; Park, KS; Yun, J | 1 |
| Davies, MG; Nicholl, SM; Roztocil, E | 1 |
| Cattaneo, MG; Lucci, G; Vicentini, LM | 1 |
| Colonna, J; Crousillac, S; Dewey, JS; Gleason, E; McMains, E | 1 |
| Baird, B; Cohen, R; Holowka, D; Ma, HT; Torres, A | 1 |
| Esche, M; Hirrlinger, PG; Pannicke, T; Reichenbach, A; Rillich, K; Weick, M; Yafai, Y | 1 |
| Choi, SY; Choi, WY; Jo, SH; Kang, JA; Kim, JS; Koo, NY; Lee, JH; Lee, SJ; Min, JH; Oh, SB; Park, K; Seo, J | 1 |
| Kanno, T; Nishizaki, T | 1 |
| Ajima, K; Kaidoh, M; Kawai, Y; Kimizuka, K; Maejima, D; Ohhashi, T | 1 |
| Chai, L; Feng, W; Li, M; Liu, L; Shi, W; Wang, J; Wang, Q; Yan, X; Zhai, C; Zhang, Q; Zhu, Y | 1 |
29 other study(ies) available for u 73122 and sphingosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Pertussis toxin inhibits phospholipase C activation and Ca2+ mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL60 leukemia cells. Implications of GTP-binding protein-coupled receptors for lysosphingolipids.
Topics: Calcium; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; HL-60 Cells; Humans; Kinetics; Lysophospholipids; Neutrophils; Pertussis Toxin; Phosphorylcholine; Platelet Activating Factor; Psychosine; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Sphingomyelin Phosphodiesterase; Sphingosine; Type C Phospholipases; Uridine Triphosphate; Virulence Factors, Bordetella | 1995 |
Sphingosine metabolism induces Ca2+ oscillations in rat pancreatic acinar cells.
Topics: Animals; Calcium; Cholecystokinin; Estrenes; Fluorescent Dyes; Fura-2; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Oscillometry; Pancreas; Phosphatidylinositols; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Sphingosine; Time Factors; Type C Phospholipases | 1993 |
An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60.
Topics: Apoptosis; Calcium; DNA Fragmentation; Estrenes; Fingolimod Hydrochloride; HL-60 Cells; Humans; Immunosuppressive Agents; Lymphocytes; Pertussis Toxin; Phosphodiesterase Inhibitors; Propylene Glycols; Pyrrolidinones; Sphingosine; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Proliferation of adult rat hepatocytes in primary cultures induced by platelet-derived growth factor is potentiated by phenylephrine.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Division; Cells, Cultured; DNA Replication; Drug Synergism; Enzyme Inhibitors; Estrenes; Ionomycin; Liver; Male; Phenylephrine; Platelet-Derived Growth Factor; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Sphingosine; Suramin; Tetradecanoylphorbol Acetate | 1998 |
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes.
Topics: Animals; Antisense Elements (Genetics); Calcium; Chelating Agents; Chlorides; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Inositol 1,4,5-Trisphosphate; Isoenzymes; Lysophospholipids; Niflumic Acid; Oligonucleotide Probes; Oocytes; Patch-Clamp Techniques; Periodicity; Phospholipase C beta; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; RNA, Messenger; Signal Transduction; Sphingosine; Thapsigargin; Type C Phospholipases; Xenopus laevis | 1998 |
Sphingosylphosphorylcholine stimulates mitogen-activated protein kinase via a Ca2+-dependent pathway.
Topics: Adenosine Triphosphate; Animals; Aorta; Bradykinin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cells, Cultured; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Kinetics; Lysophospholipids; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphorylcholine; Platelet-Derived Growth Factor; Protein Kinase C; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Swine; Thapsigargin; Virulence Factors, Bordetella | 1998 |
Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Estrenes; Glioma; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phospholipase D; Protein Kinase C; Pyrrolidinones; Rats; Receptors, Cell Surface; Sphingosine; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Sphingosylphosphorylcholine increases calcium concentration in isolated brain nuclei.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Nucleus; Estrenes; Heparin; In Vitro Techniques; Kinetics; Nimodipine; Phosphorylcholine; Pyrrolidinones; Rats; Sphingosine; Thapsigargin; Type C Phospholipases | 1999 |
Phospholipid signalling pathways in Trypanosoma cruzi growth control.
Topics: Adenylate Cyclase Toxin; Animals; Benzylamines; Carbazoles; Cell Division; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Estrenes; Indoles; Lysophospholipids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Protein Kinases; Pyrroles; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides; Trypanosoma cruzi; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Distinct Ca(2+) signalling mechanisms induced by ATP and sphingosylphosphorylcholine in porcine aortic smooth muscle cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cyclic AMP; Egtazic Acid; Estrenes; Imidazoles; Ionomycin; Manganese; Muscle, Smooth, Vascular; Phosphorylcholine; Pyrrolidinones; Sphingosine; Staurosporine; Swine; Thapsigargin; Thionucleosides; Thionucleotides; Virulence Factors, Bordetella | 2000 |
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets.
Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Cricetinae; Cyclic AMP; Estrenes; Insulin; Insulin Secretion; Islets of Langerhans; Lysophospholipids; Mice; Nifedipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Sphingosine; Type C Phospholipases | 2000 |
Activation of phosphatidylinositol-specific phospholipase C by HDL-associated lysosphingolipid. Involvement in mitogenesis but not in cholesterol efflux.
Topics: Apolipoprotein A-I; Calcium Signaling; Cells, Cultured; Cholesterol; DNA; Egtazic Acid; Enzyme Activation; Estrenes; Fibroblasts; Humans; Lipoproteins, HDL; Lysophospholipids; Mitogens; Nickel; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphorylcholine; Psychosine; Pyrrolidinones; Sphingolipids; Sphingosine; Tangier Disease; Type C Phospholipases | 2000 |
mAChRs in the grasshopper brain mediate excitation by activation of the AC/PKA and the PLC second-messenger pathways.
Topics: Acetylcholine; Adenine; Adenylyl Cyclases; Animal Communication; Animals; Brain; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dideoxyadenosine; Diglycerides; Enzyme Inhibitors; Estrenes; Grasshoppers; Inositol 1,4,5-Trisphosphate; Isoquinolines; Muscarine; Muscarinic Agonists; Phosphodiesterase Inhibitors; Purinones; Pyrrolidinones; Receptors, Muscarinic; Second Messenger Systems; Sphingosine; Sulfonamides; Thapsigargin; Thionucleotides; Type C Phospholipases | 2002 |
Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate.
Topics: Calcium; Calcium Signaling; Cells, Cultured; Estrenes; Humans; In Vitro Techniques; Lipoproteins, LDL; Lysophospholipids; Macrophage Activation; Macrophages; Monocytes; Pyrrolidinones; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Receptors, Lysophospholipid; Reverse Transcriptase Polymerase Chain Reaction; Sphingosine; Type C Phospholipases | 2003 |
Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells.
Topics: Acetophenones; Benzopyrans; Blotting, Western; Carbazoles; Cell Adhesion Molecules; Cells, Cultured; E-Selectin; Endothelium, Vascular; Estrenes; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Intercellular Adhesion Molecule-1; Lysophospholipids; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; RNA, Messenger; Signal Transduction; Sphingosine; Type C Phospholipases; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2004 |
Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils.
Topics: Calcium; Calcium Signaling; Chemotaxis; Estrenes; HL-60 Cells; Humans; Ionomycin; Lysophospholipids; Models, Biological; Neutrophils; Phosphotransferases (Alcohol Group Acceptor); Pyrrolidinones; Receptors, G-Protein-Coupled; Respiratory Burst; Signal Transduction; Sphingosine | 2005 |
Sphingosine-1-phosphate induces early response gene expression in C6 glioma cells.
Topics: Animals; Blotting, Northern; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Estrenes; Gene Expression; Genes, fos; Glioma; Lysophospholipids; Mice; Pertussis Toxin; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Time Factors | 2005 |
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chemotaxis; Enzyme Activation; Estrenes; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Lysophospholipids; Mice; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Receptors, Lysophosphatidic Acid; Sphingosine | 2006 |
Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins.
Topics: Animals; Calcium Signaling; Chemotaxis; Estrenes; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; GTP-Binding Proteins; Humans; Mice; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyrrolidinones; Receptors, Lysosphingolipid; RNA, Messenger; Sphingosine | 2007 |
Sphingosine-1-phosphate-induced oxygen free radical generation in smooth muscle cell migration requires Galpha12/13 protein-mediated phospholipase C activation.
Topics: Animals; Cell Movement; Cells, Cultured; Enzyme Activation; Estrenes; GTP-Binding Protein alpha Subunits, G12-G13; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Onium Compounds; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphodiesterase Inhibitors; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Time Factors | 2007 |
Oxytocin stimulates in vitro angiogenesis via a Pyk-2/Src-dependent mechanism.
Topics: Cell Movement; Cells, Cultured; Chromones; Endothelial Cells; Enzyme Inhibitors; Estrenes; Focal Adhesion Kinase 2; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Morpholines; Neovascularization, Physiologic; Oxytocin; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrrolidinones; Receptors, Oxytocin; RNA, Small Interfering; Signal Transduction; Sphingosine; src-Family Kinases; Type C Phospholipases; Umbilical Veins; Vascular Endothelial Growth Factor A | 2009 |
Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cells.
Topics: Amacrine Cells; Animals; Calcium; Calcium Signaling; Cells, Cultured; Chick Embryo; Estrenes; Heparin; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Lanthanoid Series Elements; Lysophospholipids; Membrane Potentials; Models, Biological; Oxadiazoles; Patch-Clamp Techniques; Pertussis Toxin; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Retina; Sphingosine; Tetraethylammonium; Thiophenes; Type C Phospholipases | 2009 |
Ca2+ waves initiate antigen-stimulated Ca2+ responses in mast cells.
Topics: Animals; Basophils; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line, Tumor; Estrenes; Immunoglobulin E; Mast Cells; Nifedipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Sphingosine; TRPC Cation Channels | 2009 |
Signalling of sphingosine-1-phosphate in Müller glial cells via the S1P/EDG-family of G-protein-coupled receptors.
Topics: Animals; Calcium; Cell Movement; Cell Proliferation; Cells, Cultured; Estrenes; Guinea Pigs; Lysophospholipids; Neuroglia; Pyrrolidinones; Receptors, Lysosphingolipid; Retina; Signal Transduction; Sphingosine; Type C Phospholipases | 2010 |
Sphingosine-1-phosphate signaling in human submandibular cells.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Boron Compounds; Calcium Signaling; Carbachol; Cell Culture Techniques; Cells, Cultured; Cholinergic Agonists; Estrenes; fas Receptor; Female; Humans; Interleukin-6; Lysophospholipids; Male; Middle Aged; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Pyrrolidinones; Receptors, Lysosphingolipid; Signal Transduction; Sjogren's Syndrome; Sphingosine; Submandibular Gland; Type C Phospholipases | 2010 |
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Lysophospholipids; Male; Maleimides; Mossy Fibers, Hippocampal; Neurons; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; Suramin; Thiazoles | 2011 |
Sphingosine 1-phosphate (S1P) induces S1P2 receptor-dependent tonic contraction in murine iliac lymph vessels.
Topics: Animals; Aspirin; Biomechanical Phenomena; Calcium Signaling; Endothelium, Lymphatic; Estrenes; Lymphatic Vessels; Lysophospholipids; Macrocyclic Compounds; Male; Mice; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Oxazoles; Pressure; Pyrazoles; Pyridines; Pyrrolidinones; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine | 2013 |
S1P induces pulmonary artery smooth muscle cell proliferation by activating calcineurin/NFAT/OPN signaling pathway.
Topics: Animals; Calcineurin; Calcium; Cations, Divalent; Cell Proliferation; Cyclosporine; Estrenes; Female; Gene Expression Regulation; Ion Transport; Lysophospholipids; Myocytes, Smooth Muscle; NFATC Transcription Factors; Osteopontin; Pioglitazone; PPAR gamma; Primary Cell Culture; Pulmonary Artery; Pyrrolidinones; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Sphingosine; Type C Phospholipases | 2019 |