u 73122 has been researched along with pd 98059 in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 31 (77.50) | 29.6817 |
| 2010's | 5 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Foreback, JL; Remick, DG; Sarma, V; Ward, PA; Yeager, NR; Younkin, EM | 1 |
| Banfi, C; Battaini, F; Cattaneo, MG; Galli, C; Mussoni, L; Risé, P; Tremoli, E; Vicentini, L | 1 |
| Leach, K; Mulholland, MW; Turner, D; Zhang, W | 1 |
| Kato, K; Kawamura, H; Kozawa, O; Matsui, N; Matsuno, H; Niwa, M; Otsuka, T; Uematsu, T | 1 |
| Bansal, R; Baron, W; de Vries, H; Hoekstra, D; Metz, B | 1 |
| Chien, CS; Chiu, CT; Hsiao, LD; Lin, CC; Luo, SF; Wang, CC; Yang, CM | 1 |
| Hatakeyama, D; Kawamura, H; Kozawa, O; Matsuno, H; Uematsu, T | 1 |
| Aragona, F; Malendowicz, LK; Nussdorfer, GG; Rebuffat, P; Tortorella, C | 1 |
| Chien, CS; Chiu, CT; Hsiao, LD; Lin, CC; Pan, SL; Wang, CC; Yang, CM | 1 |
| Felipo, V; Llansola, M; Sáez, R | 1 |
| Chien, CS; Chiu, CT; Hsiao, LD; Lin, CC; Shyr, MH; Wang, CC; Yang, CM | 1 |
| Chang, LC; Wang, JP | 1 |
| Esselman, WJ; Lee, K | 1 |
| Cueff, A; De Cian, MC; Lacoste, A; Poulet, SA | 1 |
| Hanif, S; Khan, FL; Rahman, HB; Rahman, IH; Rasheed, H; Saeed, SA; Shah, BH; Shariff, AH | 1 |
| Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Tokuda, H; Uematsu, T | 1 |
| Hayashi, K; Kadomatsu, K; Muramatsu, T | 1 |
| Jabbour, HN; Milne, SA | 1 |
| Dominguez, Z; Dubois, M; Lagarde, M; Macovschi, O; Merhi-Soussi, F; Nemoz, G; Prigent, AF | 1 |
| Farnell, MB; Genovese, K; He, H; Kogut, MH | 1 |
| Amin, AR; Biswas, MH; Hamaguchi, M; Huang, P; Ichigotani, Y; Mon, NN; Oo, ML; Yuan, H | 1 |
| DiMattina, AJ; Holland, JA; Johnson, DK; O'Donnell, RW; Stone, RI; Ziegler, LM | 1 |
| Ito, S; Ohizumi, Y; Rohra, DK; Saito, SY; Yamakuni, T | 1 |
| Adams, JW; Brunton, LL; Gustafsson, AB; Heller Brown, J; Hilal-Dandan, R; Means, CK; Morissette, MR | 1 |
| Kuan, YH; Lin, CN; Lin, RH; Tsao, LT; Wang, JP | 1 |
| Ikejima, T; Liu, YQ; Onodera, S; Tashiro, S; You, S | 1 |
| Ferjan, I; Stempelj, M | 1 |
| Bae, YS; Im, DS; Jo, SH; Kim, MK; Kim, SD; Lee, HY; Park, KS; Shin, EH | 1 |
| Greco, S; Marsigliante, S; Storelli, C | 1 |
| Ago, Y; Baba, A; Horiguchi, N; Kakuda, M; Kiyo-oka, M; Koyama, Y; Matsuda, T; Osakada, M; Shintani, N | 1 |
| Amiel, S; Asare-Anane, H; Gray, E; Huang, GC; Jones, PM; Muller, D; Persaud, SJ; Squires, PE | 1 |
| Ashizuka, M; Ito, S; Kubota, Y; Ogata, S; Satoh, S; Shirasuna, K; Takeuchi, H | 1 |
| Parsons, RL; Tompkins, JD | 1 |
| Hong, BZ; Kang, HS; Kim, HG; Kim, HN; Kwak, YG; Ma, TZ; Park, SA | 1 |
| He, P; Lee, SJ; Yoo, BK; Yun, CC | 1 |
| Brown, D; John, H; Kampik, NB; Paunescu, TG; Rothenberger, F; Stehberger, PA; Vedovelli, L; Wagner, CA; Winter, C | 1 |
| Fan, J; Ren, Y; Yin, G; Zhang, Z; Zhou, W | 1 |
| Bhattacharyya, N; Collins, MT; Dunn, D; Foster, BL; Nociti, FH; Presland, RB; Somerman, MJ; Tran, AB; Wang, L | 1 |
| Aoki, M; Hirose, E; Ishimaru, Y; Kawata, J; Matsmoto, T; Narahara, S; Ono, T; Sagara, K; Yamaguchi, Y | 1 |
40 other study(ies) available for u 73122 and pd 98059
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Blood mononuclear cell production of TNF-alpha and IL-8: engagement of different signal transduction pathways including the p42 MAP kinase pathway.
Topics: Calcium; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Genistein; GTP-Binding Proteins; Humans; Interleukin-8; Leukocytes, Mononuclear; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1998 |
Very low density lipoprotein-mediated signal transduction and plasminogen activator inhibitor type 1 in cultured HepG2 cells.
Topics: Antioxidants; Arachidonic Acid; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Hepatocellular; Cholesterol, VLDL; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Fibrinolysis; Flavonoids; Gallic Acid; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Pyrrolidinones; Signal Transduction; Thapsigargin; Tritium; Tumor Cells, Cultured; Tyrosine | 1999 |
Endothelin-1 stimulates c-fos mRNA expression in C6 glioma cells via MAP kinase pathway.
Topics: Alkaloids; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Genes, fos; Glioma; Oligopeptides; Phenanthridines; Phosphorylation; Pyrrolidinones; RNA, Messenger; Tumor Cells, Cultured | 1999 |
Endothelin-1 stimulates heat shock protein 27 induction in osteoblasts: involvement of p38 MAP kinase.
Topics: Animals; Antihypertensive Agents; Blotting, Northern; Carcinogens; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation, Enzymologic; Genistein; Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Oligopeptides; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phorbol Esters; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Propranolol; Protein Kinase C; Pyridines; Pyrrolidinones; RNA, Messenger; Skull; Staurosporine | 1999 |
PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathways.
Topics: Animals; Cell Differentiation; Cell Division; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estrenes; Fibroblast Growth Factor 2; Flavonoids; Genistein; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins; Oligodendroglia; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Processing, Post-Translational; Proteins; Pyridines; Pyrrolidinones; Rats; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stem Cells | 2000 |
Tumour necrosis factor-alpha- and interleukin-1beta-stimulated cell proliferation through activation of mitogen-activated protein kinase in canine tracheal smooth muscle cells.
Topics: Animals; Benzoquinones; Bridged-Ring Compounds; Calcium; Cell Division; Chelating Agents; DNA; Dogs; Egtazic Acid; Enzyme Activation; Estrenes; Female; Flavonoids; Interleukin-1; Isoenzymes; Lactams, Macrocyclic; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth; Norbornanes; Pertussis Toxin; Phosphorylation; Protein Kinase C; Pyrrolidinones; Quinones; Rifabutin; Thiocarbamates; Thiones; Thymidine; Trachea; Tritium; Tumor Necrosis Factor-alpha; Type C Phospholipases; Virulence Factors, Bordetella | 2000 |
Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts: involvement of p38 mitogen-activated protein kinase.
Topics: Animals; Endothelial Growth Factors; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Imidazoles; Lymphokines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Protein Kinase C; Pyridines; Pyrrolidinones; Receptor, Endothelin A; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex.
Topics: Adenine; Androstadienes; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Hydrocortisone; Indomethacin; Naphthalenes; Nifedipine; Oligopeptides; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase C; Pyrazoles; Pyrrolidinones; Receptors, Endothelin; Signal Transduction; Type C Phospholipases; Tyrphostins; Wortmannin; Zona Fasciculata; Zona Reticularis | 2001 |
Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway.
Topics: Animals; Benzoquinones; Calcium; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Genistein; Humans; Lactams, Macrocyclic; Lipoproteins, LDL; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Pyrrolidinones; Quinones; ras Proteins; Rats; Rats, Sprague-Dawley; Rifabutin; Staurosporine; Virulence Factors, Bordetella | 2001 |
NMDA-induced phosphorylation of the microtubule-associated protein MAP-2 is mediated by activation of nitric oxide synthase and MAP kinase.
Topics: Animals; Cells, Cultured; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Flavonoids; Indazoles; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; N-Methylaspartate; Naphthalenes; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Phosphodiesterase Inhibitors; Phosphorylation; Pyrrolidinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2001 |
Mechanisms of thrombin-induced MAPK activation associated with cell proliferation in human cultured tracheal smooth muscle cells.
Topics: Androstadienes; Benzoquinones; Blotting, Western; Cell Division; Cells, Cultured; Chelating Agents; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Genistein; Humans; Indoles; Lactams, Macrocyclic; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Isoforms; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyrrolidinones; Quinones; ras Proteins; Rifabutin; Thrombin; Time Factors; Trachea; Transfection; Virulence Factors, Bordetella; Wortmannin | 2001 |
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin | 2001 |
cAMP potentiates H(2)O(2)-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation.
Topics: Colforsin; Cyclic AMP; Drug Synergism; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Hydrogen Peroxide; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrrolidinones; Receptors, Antigen, T-Cell; T-Lymphocytes | 2001 |
Noradrenaline and alpha-adrenergic signaling induce the hsp70 gene promoter in mollusc immune cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Chromones; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Hemocytes; HSP70 Heat-Shock Proteins; Indoles; Isoproterenol; Isoquinolines; Luciferases; Morpholines; Naphthalenes; Norepinephrine; Ostreidae; Pertussis Toxin; Phenylephrine; Phosphodiesterase Inhibitors; Prazosin; Promoter Regions, Genetic; Propranolol; Pyrrolidinones; Signal Transduction; Sulfonamides; Transfection; Virulence Factors, Bordetella | 2001 |
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
Topics: Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Flavonoids; Humans; In Vitro Techniques; Indomethacin; Kinetics; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Pyrrolidinones; Serotonin; Thromboxane A2; Verapamil | 2001 |
Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells.
Topics: Analysis of Variance; Animals; Butadienes; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Chaperones; Naphthalenes; Neoplasm Proteins; Nitriles; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Staurosporine; Stimulation, Chemical; Time Factors; Type C Phospholipases | 2002 |
Requirement of chondroitin sulfate/dermatan sulfate recognition in midkine-dependent migration of macrophages.
Topics: Androstadienes; Animals; Benzoquinones; Carrier Proteins; Cell Movement; Chondroitin Sulfates; Cytokines; Dermatan Sulfate; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Lactams, Macrocyclic; Macrophages; Mice; Midkine; Protein Tyrosine Phosphatases; Pyrazoles; Pyrimidines; Pyrrolidinones; Quinones; Rats; Reverse Transcriptase Polymerase Chain Reaction; Rifabutin; RNA, Messenger; Signal Transduction; Wortmannin | 2001 |
Prostaglandin (PG) F(2alpha) receptor expression and signaling in human endometrium: role of PGF(2alpha) in epithelial cell proliferation.
Topics: Cell Division; Cell Line; Cells, Cultured; Dinoprost; Endometrium; Enzyme Inhibitors; Epithelial Cells; Estrenes; Female; Flavonoids; Gene Expression; GTP-Binding Proteins; Humans; In Situ Hybridization; Menstrual Cycle; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidinones; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Type C Phospholipases | 2003 |
Mechanisms involved in the stimulation of prostacyclin synthesis by human lymphocytes in human umbilical vein endothelial cells.
Topics: Butadienes; Cell Communication; Cell Line; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Estrenes; Flavonoids; Humans; Lymphocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Pyrrolidinones; Type C Phospholipases; Umbilical Veins | 2003 |
Pharmacological analysis of signal transduction pathways required for oxidative burst in chicken heterophils stimulated by a Toll-like receptor 2 agonist.
Topics: Androstadienes; Animals; Animals, Newborn; Carbazoles; Chickens; Estrenes; Flavonoids; Indoles; Lipopolysaccharides; Male; Membrane Glycoproteins; Neutrophils; Nitriles; Pyrrolidinones; Receptors, Cell Surface; Respiratory Burst; Signal Transduction; Sulfones; Teichoic Acids; Toll-Like Receptor 2; Toll-Like Receptors; Wortmannin | 2003 |
The PLC-PKC cascade is required for IL-1beta-dependent Erk and Akt activation: their role in proliferation.
Topics: Animals; Antigens, Differentiation; BALB 3T3 Cells; Cell Division; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Glycoproteins; Immunoblotting; Indoles; Interleukin-1; Maleimides; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Neural Cell Adhesion Molecule L1; Phospholipase C gamma; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinase C; Pyrrolidinones; Receptors, Immunologic; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Type C Phospholipases | 2003 |
Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein.
Topics: Arachidonic Acids; Cells, Cultured; Chromones; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Imidazoles; Indoles; Lipoproteins, LDL; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Morpholines; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phospholipases A; Protein Kinase C; Pyridines; Pyrrolidinones; Reactive Oxygen Species; Signal Transduction; src-Family Kinases; Type C Phospholipases; Umbilical Veins | 2003 |
Evidence for the involvement of protein kinase C in acidic pH-induced contraction in spontaneously hypertensive rat aorta.
Topics: Animals; Aorta, Thoracic; Bridged-Ring Compounds; Butadienes; Drug Synergism; Estrenes; Flavonoids; Hydrogen-Ion Concentration; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nitriles; Norbornanes; Phosphatidate Phosphatase; Phosphatidylinositol Diacylglycerol-Lyase; Potassium Chloride; Propranolol; Protein Kinase C; Pyrrolidinones; Rats; Rats, Inbred SHR; Thiocarbamates; Thiones; Type C Phospholipases; Tyrphostins | 2004 |
Lysophosphatidic acid induces hypertrophy of neonatal cardiac myocytes via activation of Gi and Rho.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Blotting, Western; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Inhibitory Concentration 50; Luciferases; Lysophospholipids; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Myocytes, Cardiac; Pertussis Toxin; Phosphatidylinositols; Protein Biosynthesis; Protein Kinase C; Proteins; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA, Messenger; Time Factors; Transfection; Type C Phospholipases | 2004 |
Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways.
Topics: Animals; Butadienes; Calcium; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; Immunoblotting; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2005 |
Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells.
Topics: Androstadienes; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, High Pressure Liquid; Diterpenes; Diterpenes, Kaurane; Enzyme Activation; Enzyme Inhibitors; Estrenes; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Humans; Molecular Structure; Phagocytosis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrrolidinones; Staurosporine; Time Factors; Type C Phospholipases; U937 Cells; Ultraviolet Rays; Wortmannin | 2005 |
Signaling pathway in nerve growth factor induced histamine release from rat mast cells.
Topics: Analysis of Variance; Androstadienes; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Flavonoids; Histamine; Imidazoles; Indoles; Male; Maleimides; Mast Cells; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tyrosine; Wortmannin | 2005 |
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chemotaxis; Enzyme Activation; Estrenes; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Lysophospholipids; Mice; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Receptors, Lysophosphatidic Acid; Sphingosine | 2006 |
Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin.
Topics: Analysis of Variance; Biological Transport; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chromones; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Flavonoids; Humans; Immunoblotting; Indoles; Kallidin; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyrrolidinones; Stimulation, Chemical; Tetrahydroisoquinolines | 2006 |
Expression of prokineticin receptors in mouse cultured astrocytes and involvement in cell proliferation.
Topics: Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Calcium; Cell Proliferation; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Estrenes; Flavonoids; Gastrointestinal Hormones; Gene Expression; Mice; Neuropeptides; Pyrrolidinones; Receptors, G-Protein-Coupled; Vascular Endothelial Growth Factor, Endocrine-Gland-Derived | 2006 |
Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases.
Topics: Aniline Compounds; Antibodies, Monoclonal; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Communication; Cell Line; Cells, Cultured; Estrenes; Extracellular Fluid; Flavonoids; Glucose; Humans; Immunohistochemistry; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitogen-Activated Protein Kinases; Phenethylamines; Propylamines; Protein Kinase C; Protein Kinases; Pyrrolidinones; Receptors, Calcium-Sensing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Stimulation, Chemical; Sulfonamides; Type C Phospholipases | 2006 |
Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts.
Topics: Anthracenes; Bone and Bones; Calcium; Calcium Signaling; Cations, Divalent; Cyclooxygenase 2; Dinoprostone; Estrenes; Fibroblasts; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; Receptors, Calcium-Sensing; RNA, Messenger; Type C Phospholipases | 2006 |
Identification of intracellular signaling cascades mediating the PACAP-induced increase in guinea pig cardiac neuron excitability.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estrenes; Flavonoids; Guinea Pigs; Mitogen-Activated Protein Kinases; Myocardium; Neurons; Parasympathetic Fibers, Postganglionic; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrrolidinones; Signal Transduction | 2008 |
Basic fibroblast growth factor increases intracellular magnesium concentration through the specific signaling pathways.
Topics: Androstadienes; Cell Line; Chromones; Dose-Response Relationship, Drug; Endothelial Cells; Estrenes; Fibroblast Growth Factor 2; Flavonoids; Genistein; Humans; Imidazoles; Intracellular Space; Magnesium; Microscopy, Fluorescence; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrrolidinones; Signal Transduction; Tyrphostins; Wortmannin | 2009 |
Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells.
Topics: Butadienes; Caco-2 Cells; Chromones; Enzyme Inhibitors; ErbB Receptors; Estrenes; Flavonoids; Focal Adhesion Kinase 2; Humans; Intestines; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Morpholines; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C beta; Pyrrolidinones; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2011 |
Aldosterone stimulates vacuolar H(+)-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C-dependent pathway.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Animals; Chelating Agents; Diglycerides; Egtazic Acid; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Proteins; Humans; Isoquinolines; Kidney Tubules, Collecting; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Protein Kinase C; Pyrrolidinones; Signal Transduction; Sulfonamides; Suramin; Type C Phospholipases; Vacuolar Proton-Translocating ATPases | 2011 |
The release of glutamate from cortical neurons regulated by BDNF via the TrkB/Src/PLC-γ1 pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cerebral Cortex; Chromones; Embryo, Mammalian; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Glutamic Acid; Indole Alkaloids; Morpholines; Neurons; Phospholipase C gamma; Phosphorylation; Primary Cell Culture; Pyrimidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, trkB; Signal Transduction; src-Family Kinases | 2013 |
Vitamin D represses dentin matrix protein 1 in cementoblasts and osteocytes.
Topics: Animals; Calcitriol; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dental Cementum; Dose-Response Relationship, Drug; Down-Regulation; Estrenes; Extracellular Matrix Proteins; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Flavonoids; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Indoles; Maleimides; MAP Kinase Signaling System; Mice; Osteocytes; Protein Kinase C; Pyrrolidinones; Receptors, Calcitriol; Type C Phospholipases; Vitamins; Vorinostat | 2014 |
Mechanism of tissue factor production by monocytes stimulated with neutrophil elastase.
Topics: Calcium Channel Blockers; Carbazoles; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Gene Expression Regulation; Humans; Imidazoles; Indoles; Leukocyte Elastase; Maleimides; Monocytes; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; RNA, Messenger; Signal Transduction; Thromboplastin; Type C Phospholipases | 2015 |