u 73122 has been researched along with inositol 1,4,5-trisphosphate in 173 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 71 (41.04) | 18.2507 |
| 2000's | 81 (46.82) | 29.6817 |
| 2010's | 21 (12.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Justen, JM; Leach, KL; Sam, LM; Smith, RJ | 1 |
| Bleasdale, JE; Conn, PM; Hawes, BE; Janovick, JA; Waters, SB | 1 |
| Williams, JA; Yule, DI | 1 |
| Bala, GA; Bleasdale, JE; Bundy, GL; Justen, JM; Sam, LM; Smith, RJ | 1 |
| Smallridge, RC; Tsokos, GC; Vassilopoulos, D | 1 |
| Bold, RJ; Ishizuka, J; Thompson, JC; Townsend, CM | 1 |
| Eusebi, F; Giovannelli, A; Grassi, F; Limatola, C; Mattei, E; Ragozzino, D | 1 |
| Cotter, DA; Lydan, MA | 1 |
| Esaki, C; Kitajima, Y; Osada, K; Seishima, M; Yamada, T | 1 |
| Owyang, C; Tsunoda, Y | 1 |
| Hicks, JL; Salter, MW | 1 |
| Chin, KV; Hait, WN; Yang, JM | 1 |
| Chen, TH; Hsu, WH | 1 |
| Grierson, JP; Meldolesi, J | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K; Shirakawa, M; Tsujimoto, A; Uchiyama, Y; Yoshino, H | 1 |
| Bosch, RR; de Pont, JJ; Engbersen, R; Van de Put, FH; Van Hoof, HJ; Willems, PH | 1 |
| Alter, CA; Amagasu, M; Jolly, YC; Major, C; Shah, K; Wolf, BA | 1 |
| Catt, KJ; Hunyady, L; Krsmanovic, LZ; Stojilkovic, SS; Zheng, L | 1 |
| Hoyland, J; Mason, WT; Oberleithner, H; Schwab, A; Westphale, HJ; Wojnowski, L | 1 |
| Behar, J; Biancani, P; Bitar, KN; Harnett, KM; Hillemeier, C; Rhim, BY; Sohn, UD | 1 |
| Nibbering, PH; van Furth, R; Zheng, L | 1 |
| Altenberg, GA; Bergmann, JS; Johnson, KM; Reuss, L; Subramanyam, M | 1 |
| Catt, KJ; Kukuljan, M; Rojas, E; Stojilković, SS; Tomić, M | 1 |
| Essington, TE; Shayman, JA; Williams, JA; Wu, D; Yule, DI | 1 |
| Fujimoto, M; Nakajima, S; Shigeri, Y | 1 |
| Gesek, FA | 1 |
| Andersson, T; Hellberg, C; Molony, L; Zheng, L | 1 |
| Armant, DR; Stachecki, JJ | 1 |
| Hoffmann, EK; Hougaard, C; Jorgensen, NK; Lambert, IH; Pedersen, S; Wybrandt, GB | 1 |
| Berke, G; Binah, O; Felzen, B; Gardner, P | 1 |
| Helliwell, RM; Large, WA | 1 |
| Kinnamon, SC; Mackay-Sim, A; Ogura, T | 1 |
| Hildebrandt, JP; Meves, H; Plant, TD | 1 |
| Gallacher, DV; Lloyd Mills, C; Mogami, H | 1 |
| De Meijer, J; Van den Broek, AT; Van der Horst, DJ; Van Marrewijk, WJ; Vroemen, SF | 1 |
| Bitar, KN; Deutsch, DE; Hillemeier, AC | 1 |
| Chen, TH; Hsu, WH; Lee, B; Yang, C | 1 |
| Inamura, K; Kashiwayanagi, M; Kurihara, K | 1 |
| Aschner, JL; Fletcher, PW; Lum, H; Malik, AB | 1 |
| Abdel-Latif, AA; Akhtar, RA; Ding, KH; Husain, S; Isales, CM | 1 |
| Kang, HY; Kang, WH; Lee, C | 1 |
| Hori, M; Kuzuya, T; Otsu, K; Tada, M; Toyofuku, T; Yabuki, M | 1 |
| Gunasekar, PG; Isom, GE; Kane, MD; Yang, CW | 1 |
| Lee, SJ; Shen, SS | 1 |
| Cathcart, MK; Li, Q | 1 |
| Ech-Chadli, H; Lafond, J; Robidoux, J; Simoneau, L; St-Pierre, S | 1 |
| Nishino, H; Owyang, C; Tsunoda, Y | 1 |
| Churchill, GC; Louis, CF | 1 |
| Han, JK; Kim, MJ; Noh, SJ; Shim, S | 1 |
| Kelly, ME; Ryan, JS; Tao, QP | 1 |
| Idestrup, CP; Salter, MW | 1 |
| Chen, CC; Wang, JP | 1 |
| Iversen, JG; Nicolaysen, G; Wassdal, I | 1 |
| Inoue, M; Nakayamada, H; Tokuyama, S; Ueda, H | 1 |
| de Smedt, H; Droogmans, G; Nilius, B; Viana, F | 1 |
| Chin, TY; Chueh, SH | 1 |
| Abebe, W; Mustafa, SJ | 1 |
| Bonuglia, M; Gazzaniga, PP; Gresele, P; Pulcinelli, FM | 1 |
| Boland, RL; de Boland, AR; Vazquez, G | 1 |
| Friedman, PA; Gesek, FA; Morley, P; Whitfield, JF; Willick, GE | 1 |
| Fujii, M; Hirata, H; Kamata, H; Ogawa, T; Ohtsubo, M; Yagisawa, H | 1 |
| Ho, CM; Jan, CR; Tseng, CJ; Wu, SN | 1 |
| Boland, R; Picotto, G; Vazquez, G | 1 |
| Bender, M; Geiger, H; Gross, W; Herrero, M; Mondorf, UF; Olbrich, HG; Piiper, A; Scheuermann, E | 1 |
| Walz, B; Zimmermann, B | 1 |
| Biskup, B; Gradmann, D; Thiel, G | 1 |
| Burgstahler, AD; Hirata, K; Mattei, E; Nathanson, MH; Okazaki, K; Sears, ML | 1 |
| Camiña, JP; Casabiell, X; Casanueva, FF | 1 |
| Kinnamon, SC; Ogura, T | 1 |
| Blackwood, RA; Harper, HA; Pan, PM; Sitrin, RG; Todd, RF | 1 |
| Jan, CR; Tseng, CJ | 1 |
| Bonin, A; Khan, NA | 1 |
| Chen, TH; Cheng, H; Hsu, WH; Yibchok-Anun, S | 1 |
| Chida, K; Ichiyama, A; Kanai, M; Nakamura, H; Oki, Y; Suda, T; Uchida, C; Xue, HH; Zhao, DM | 1 |
| Brandis, M; Epting, T; Fischer-Riepe, P; Gordjani, N; Greger, RF; Leipziger, J; Nitschke, R | 1 |
| Bathgate, R; Cook, DI; Emerson, M; Harding, E; Lu, DP; O'Neill, C; Stojanov, T; Travis, AR | 1 |
| Chiang, HT; Chou, KJ; Jan, CR; Tseng, CJ | 1 |
| Carey, MB; Matsumoto, SG | 1 |
| Geiger, JD; Holden, CP; Mayne, M; Nath, A | 1 |
| Beale, SI; Im, CS | 1 |
| Boekhoff, I; Breer, H; Noé, J; Vogl, A | 1 |
| Kudoh, A; Matsuki, A | 1 |
| Aoki, T; Mizoguchi, H; Narita, M; Ohsawa, M; Suzuki, T; Tseng, LF | 1 |
| Gross, KW; Hajduczok, G; Ryan, MJ | 1 |
| Miyamoto, A; Ohshika, H | 1 |
| Aragona, F; Malendowicz, LK; Mazzocchi, G; Nussdorfer, GG | 1 |
| Ellis, EF; Floyd, CL; Rzigalinski, BA; Sitterding, HA; Weber, JT; Willoughby, KA | 1 |
| Chen, WC; Cheng, JS; Chou, KJ; Huang, JK; Jan, CR; Lee, KC; Tang, KY | 1 |
| Hirayama, T; Katagiri, T; Shinozaki, K; Takahashi, S; Yamaguchi-Shinozaki, K | 1 |
| Grama, L; Lustyik, G; Somogyi, B; Visegrády, A | 1 |
| Boss, WF; Chang, SC; Heilmann, I; Kaufman, PB; Perera, IY | 1 |
| Adachi, R; Hayakawa, T; Kasahara, T; Kusui, K; Matsui, S; Suzuki, K; Yamaguchi, T | 1 |
| Bird, GS; Braun, FJ; Broad, LM; Kurosaki, T; Lievremont, JP; Putney, JW | 1 |
| Bayliss, DA; Lei, Q; Talley, EM | 1 |
| Allbritton, NL; Black, SL; Fissore, RA; Fukami, K; Luzzi, V; Smyth, J; Takenawa, T; Wu, H | 1 |
| Huang, JK; Jan, CR; Yu, CC | 1 |
| Furuya, K; Nakano, H; Yamagishi, S | 1 |
| Chang, CH; Chang, HT; Cheng, JS; Jan, CR; Lo, YK; Lu, T; Tang, KY; Wang, JL | 1 |
| Barnstable, CJ; Han, MH; Kawasaki, A; Wei, JY | 1 |
| Kim, KT; Kim, TD; Lee, JU; Seong, JK; Suh, BC | 1 |
| Chang, HT; Cheng, JS; Chou, KJ; Huang, JK; Jan, CR; Law, YP; Lee, KC; Su, W; Tang, KY; Tseng, LL; Wang, JL | 1 |
| Cheng, JS; Chou, KJ; Fang, HC; Jan, CR; Law, YP; Lee, KC; Su, W; Tseng, LL; Wang, JL | 1 |
| Akaike, A; Kaneko, S; Kanki, H; Kinoshita, M; Mori, Y; Satoh, M | 1 |
| Hirayama, T; Kawahara, T; Kurazono, H; Maeda, K; Mawatari, K; Moss, J; Nakaya, Y; Ogushi, K; Takahashi, A; Wada, A | 1 |
| Chang, HT; Chen, WC; Chou, KJ; Huang, JK; Jan, CR; Law, YP; Lee, KC; Lo, YK; Su, W; Tang, KY; Wang, JL | 1 |
| Chen, WC; Cheng, JS; Chou, KJ; Huang, JK; Jan, CR; Lee, KC; Tang, KY; Tseng, LL; Wang, JL | 1 |
| Elsner, N; Heinrich, R; Wenzel, B | 1 |
| Koganezawa, M; Shimada, I | 1 |
| Coté, GG; Crain, RC; Zhang, XG | 1 |
| Colmers, WF; Ford, CP; Peuckmann, V; Smith, PA; Stemkowski, PL; Tse, FW | 1 |
| Lidofsky, SD; Melnick, RF; Moore, AL; Roe, MW | 1 |
| Haddock, RE; Hill, CE | 1 |
| Arai, H; Ashida, N; Kita, T; Takechi, H | 1 |
| Miller, S; Napier, A; Wekesa, KS | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C | 1 |
| Kikuyama, M; Tazawa, M | 1 |
| Cazenave, JP; Eckly, A; Freund, M; Gachet, C; Goncalves, I; Jackson, SP; Lanza, F; Mangin, P; Yuan, Y | 1 |
| Bonomo, M; Burlando, B; Dondero, F; Fabbri, E; Viarengo, A | 1 |
| Alyeshmerni, N; Apone, F; Chalmers, D; Chrispeels, MJ; Colucci, G; Wiens, K | 1 |
| Bolton, TB; Gordienko, DV; Tsvilovskyy, VV; Tsytsyura, YD; Zholos, AV | 1 |
| Buck, SM; Klein, JD; Roberts, BR; Tong, DC; Tumlin, JA | 1 |
| Anderson, CD; Belous, AE; Chari, RS; Knox, CD; Nicoud, IB; Pierce, JM; Pinson, CW; Wakata, A | 1 |
| Déniz, A; Marrero, I | 1 |
| Buchuk, D; Cárdenas, C; Carrasco, MA; Jaimovich, E; Müller, M; Pérez, F; Quest, AF | 1 |
| Jan, CR; Liu, CP | 1 |
| Chakrabarti, MK; Gupta, DD; Saha, S | 1 |
| Bény, JL; Koenigsberger, M; Lamboley, M; Meister, JJ; Pittet, P; Sauser, R | 1 |
| Borski, RJ; Grau, EG; Hirano, T; Strom, CN; Tipsmark, CK; Weber, GM | 1 |
| He, XK; Huang, XY; Pan, L; Sun, FZ; Yang, LH; Zhang, D | 1 |
| López, JJ; Pariente, JA; Redondo, PC; Rosado, JA; Salido, GM | 1 |
| Ha, DC; Han, S; Kim, KT; Kim, TD | 1 |
| Louw, AI; Maritz-Olivier, C; Neitz, AW | 1 |
| Falcinelli, E; Gresele, P; Guglielmini, G; Torti, M | 1 |
| Chiong, M; Diaz-Araya, G; Estrada, M; Ibarra, C; Jaimovich, E; Lavandero, S; Parra, V; Soto, D; Vicencio, JM | 1 |
| Bae, YS; Bootman, MD; Byun, HM; Hong, JH; Jo, H; Kim, MS; Lee, SI; Moon, SJ; Roderick, HL; Seo, JT; Shin, DM | 1 |
| Brown, Z; Cronshaw, DG; Kouroumalis, A; Parry, R; Ward, SG; Webb, A | 1 |
| Cui, SJ; Gao, F; Han, JL; Liu, HT; Sun, DY; Zhou, RG | 1 |
| Kiss, K; Salamon, S; Szeberényi, J; Töröcsik, B | 1 |
| Banach, K; Kapur, N; Mignery, GA | 1 |
| Liu, QH; Wang, YX; Zheng, YM | 1 |
| Chen, P; Halpern, M; Quan, W; Wang, D | 1 |
| Dibas, A; He, S; Prasanna, G; Yorio, T | 1 |
| Abdelly, C; Bordenave, M; Ghars, MA; Lefebvre, D; Leprince, AS; Mazars, C; Parre, E; Richard, L; Savouré, A; Thiery, L | 1 |
| Banach, K; Kapur, N | 1 |
| Aromataris, EC; Barritt, GJ; Castro, J; Jones, L; Litjens, T; Nguyen, T; Rychkov, GY | 1 |
| Iwamoto, T; Katsuragi, T; Migita, K; Sato, C; Usune, S; Zhao, Y | 1 |
| Beraldo, FH; Garcia, CR; Mikoshiba, K | 1 |
| Arnold, JM; Fan, J; Feng, Q; Peng, T; Shen, E; Zhang, Y | 1 |
| Jong, YJ; Kumar, V; O'Malley, KL | 1 |
| Bland, R; Fletcher, S; Molostvov, G; Zehnder, D | 1 |
| Murata, Y; Nakamura, A; Nakamura, T; Ouyang, Q; Ozaki, M; Sato, H | 1 |
| Angelini, DJ; Fan, C; Guggino, WB; Johns, RA; Li, Y; Liang, L; Su, Q | 1 |
| Albert, AP; Ju, M; Large, WA; Saleh, SN; Shi, J | 1 |
| Contín, MA; Giusto, NM; Guido, ME; Ilincheta, M; Salvador, G; Verra, DM | 1 |
| Morita, T; Nezu, A; Tanimura, A; Tojyo, Y | 1 |
| Chen, CY; Kuo, SY; Yang, YH | 1 |
| Hirakura, Y; Ikeda, M; Sugiyama, T; Takeda, M; Yoshioka, T | 1 |
| Lasorsa, DR; Mastrofrancesco, L; Mira, A; Ranieri, M; Svelto, M; Valenti, G | 1 |
| Hasegawa, Y; Imai, J; Ishigaki, Y; Ishihara, H; Kaneko, K; Katagiri, H; Oka, Y; Suzuki, T; Uno, K; Yamada, T | 1 |
| Banumathi, E; Curtis, TM; Gurunathan, S; McGeown, JG; O'Connor, A; Simpson, DA | 1 |
| Habara, Y; Moustafa, A; Sakamoto, KQ | 1 |
| Laframboise, AJ; Zielinski, BS | 1 |
| Hessari, NM; Lee, I; Pan, L; Wu, X; Xu, J; Zhang, X; Zhao, D | 1 |
| Bruce, IC; Chen, CC; Dou, HQ; Guo, S; Shang, S; Sun, JP; Xu, YF; Yu, X; Zheng, LH; Zhou, Z | 1 |
| Hanaoka, K; Hosoya, T; Kawamura, M; Udagawa, T | 1 |
| Chi, CC; Chou, CT; Chu, ST; Ho, CM; Hsieh, YD; Jan, CR; Kuo, CC; Liang, WZ; Su, HH; Tseng, LL | 1 |
| Araki, M; Nagayama, T | 1 |
| Joseph, L; Mei, L; Song, T; Wang, YX; Yadav, VR; Zheng, YM | 1 |
| Beierwaltes, WH; Garvin, JL; Mendez, M; Ortiz-Capisano, MC; Reddy, M | 1 |
| Hill, WG; Robson, SC; Sun, X; Yu, W | 1 |
| Habara, Y; Moustafa, A | 1 |
| Bird, IM; Boeldt, DS; Grummer, MA; Magness, RR | 1 |
| AlSuleimani, YM; Hiley, CR | 1 |
173 other study(ies) available for u 73122 and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Postreceptor events associated with human neutrophil activation by interleukin-8.
Topics: Antibodies; Arachidonic Acid; Benzoquinones; Blotting, Western; Calcium; Cell Degranulation; Estrenes; Exocytosis; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-8; Isoenzymes; Isomerism; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Pyrrolidinones; Receptors, Immunologic; Receptors, Interleukin-8A; Time Factors; Type C Phospholipases | 1992 |
Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production.
Topics: Animals; Calcium; Cells, Cultured; Estrenes; Female; Fura-2; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Luteinizing Hormone; Multivariate Analysis; Pituitary Gland; Pyrrolidinones; Rats; Rats, Inbred Strains; Sodium Fluoride; Time Factors; Type C Phospholipases | 1992 |
U73122 inhibits Ca2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells.
Topics: Animals; Calcium; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Estrenes; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Pancreas; Pyrrolidinones; Rats; Rats, Inbred Strains; Sincalide; Type C Phospholipases | 1992 |
Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness.
Topics: Cell Membrane; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyrrolidinones; Signal Transduction; Type C Phospholipases | 1990 |
Effects of an aminosteroid inhibitor of phospholipase C-dependent processes on the TCR-mediated signal transduction pathway in human T cells.
Topics: Adjuvants, Immunologic; Calcium; Calcium-Transporting ATPases; CD3 Complex; Enzyme Inhibitors; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Lymphocyte Activation; Protein Kinase C; Pyrrolidinones; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 1995 |
Secretin potentiates cholecystokinin-stimulated amylase release by AR4-2J cells via a stimulation of phospholipase C.
Topics: Amylases; Animals; Calcium; Cells, Cultured; Cholecystokinin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Pyrrolidinones; Rats; Second Messenger Systems; Secretin; Type C Phospholipases | 1995 |
Acetylcholine-activated inward current induces cytosolic Ca2+ mobilization in mouse C2C12 myotubes.
Topics: Acetylcholine; Animals; Calcium; Cell Line; Culture Media; Cytosol; Electrophysiology; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Heparin; Inositol 1,4,5-Trisphosphate; Ion Transport; Kinetics; Membrane Potentials; Mice; Muscles; Permeability; Pyrrolidinones | 1995 |
The role of Ca2+ during spore germination in Dictyostelium: autoactivation is mediated by the mobilization of Ca2+ while amoebal emergence requires entry of external Ca2+.
Topics: Animals; Calcium; Cell Compartmentation; Dictyostelium; Estrenes; Fungal Proteins; Gallic Acid; Inositol 1,4,5-Trisphosphate; Lanthanum; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Protozoan Proteins; Pyrrolidinones; Signal Transduction; Spores, Fungal | 1995 |
Pharmacologic evidence for involvement of phospholipase C in pemphigus IgG-induced inositol 1,4,5-trisphosphate generation, intracellular calcium increase, and plasminogen activator secretion in DJM-1 cells, a squamous cell carcinoma line.
Topics: Calcium; Calcium Channel Blockers; Carcinoma, Squamous Cell; Cell Communication; Cell Membrane; Cell Survival; Estrenes; Humans; Immunoglobulin G; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Pemphigus; Plasminogen Activators; Pyrrolidinones; Skin Neoplasms; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Differential involvement of phospholipase A2/arachidonic acid and phospholipase C/phosphoinositol pathways during cholecystokinin receptor activated Ca2+ oscillations in pancreatic acini.
Topics: Aminobenzoates; Amylases; Animals; Arachidonic Acid; Calcium; Chlorobenzoates; Cinnamates; Estrenes; Imidazoles; Inositol 1,4,5-Trisphosphate; Male; ortho-Aminobenzoates; Pancreas; Periodicity; Phospholipases A; Phospholipases A2; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Ryanodine; Signal Transduction; Sincalide; Type C Phospholipases | 1993 |
ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Egtazic Acid; Estrenes; Fetus; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Patch-Clamp Techniques; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Spinal Cord; Terpenes; Thapsigargin; Thionucleotides; Time Factors; Type C Phospholipases | 1995 |
Involvement of phospholipase C in heat-shock-induced phosphorylation of P-glycoprotein in multidrug resistant human breast cancer cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cycloheximide; Diglycerides; Drug Resistance, Multiple; Estrenes; Hot Temperature; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Phosphorylation; Protein Kinase C; Pyrrolidinones; Staurosporine; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
U-73122 inhibits carbachol-induced increases in [Ca2+]i, IP3, and insulin release in beta-TC3 cells.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Drug Interactions; Estrenes; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Pyrrolidinones; Type C Phospholipases | 1995 |
Shear stress-induced [Ca2+]i transients and oscillations in mouse fibroblasts are mediated by endogenously released ATP.
Topics: Adenosine Triphosphate; Animals; Apyrase; Biomechanical Phenomena; Calcium; Estrenes; Homeostasis; Hydrolysis; Inositol 1,4,5-Trisphosphate; L Cells; Mice; Pyrrolidinones; Sodium Chloride | 1995 |
Effect of 12-hydroxyeicosatetraenoic acid on cytosolic calcium in human neutrophils.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Calcium; Cytosol; Estrenes; Fluorescence; Fura-2; Humans; Hydroxyeicosatetraenoic Acids; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Neutrophils; Pertussis Toxin; Pyrrolidinones; Stimulation, Chemical; Type C Phospholipases; Virulence Factors, Bordetella | 1994 |
Induction of Ca2+ oscillations by selective, U73122-mediated, depletion of inositol-trisphosphate-sensitive Ca2+ stores in rabbit pancreatic acinar cells.
Topics: Animals; Calcium; Cell Membrane Permeability; Estrenes; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Pancreas; Pyrrolidinones; Rabbits; Sincalide; Spectrometry, Fluorescence; Type C Phospholipases | 1994 |
U-73122 does not specifically inhibit phospholipase C in rat pancreatic islets and insulin-secreting beta-cell lines.
Topics: Animals; Cell Line; Estrenes; Glucose; Glyceraldehyde; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 1994 |
Sequential activation of phospholipase-C and -D in agonist-stimulated gonadotrophs.
Topics: Animals; Calcium; Cells, Cultured; Diglycerides; Enzyme Activation; Estrenes; Female; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Phospholipase D; Pituitary Gland; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Cell transformation induces a cytoplasmic Ca2+ oscillator in Madin-Darby canine kidney cells.
Topics: Animals; Biological Clocks; Bradykinin; Calcium; Calcium-Transporting ATPases; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cytoplasm; Dogs; Estrenes; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Ionomycin; Pyrrolidinones; Terpenes; Thapsigargin; Type C Phospholipases | 1994 |
Differential signal transduction pathways in cat lower esophageal sphincter tone and response to ACh.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Analysis of Variance; Animals; Benzimidazoles; Calmodulin; Cats; Diglycerides; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Estrenes; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Piperazines; Protein Kinase Inhibitors; Pyrrolidinones; Signal Transduction; Type C Phospholipases | 1994 |
Stimulation of the intracellular killing of Staphylococcus aureus by human monocytes mediated by Fc gamma receptors I and II.
Topics: Antibodies, Monoclonal; Blood Bactericidal Activity; Calcium; Cross-Linking Reagents; Estrenes; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Monocytes; Pertussis Toxin; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, IgG; Signal Transduction; Staphylococcus aureus; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Muscarinic stimulation of gallbladder epithelium. I. Electrophysiology and signaling mechanisms.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Cell Membrane; Electrophysiology; Epithelium; Estrenes; Gallbladder; In Vitro Techniques; Indomethacin; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Methylene Blue; Necturus; Pyrrolidinones; Quinuclidinyl Benzilate; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1993 |
Mechanism of agonist-induced [Ca2+]i oscillations in pituitary gonadotrophs.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Cytoplasm; Estrenes; Female; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Oscillometry; Ovariectomy; Pituitary Gland; Pyrrolidinones; Rats; Terpenes; Thapsigargin; Time Factors; Type C Phospholipases | 1993 |
Sphingosine metabolism induces Ca2+ oscillations in rat pancreatic acinar cells.
Topics: Animals; Calcium; Cholecystokinin; Estrenes; Fluorescent Dyes; Fura-2; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Oscillometry; Pancreas; Phosphatidylinositols; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Sphingosine; Time Factors; Type C Phospholipases | 1993 |
Neuropeptide YY1 receptors-mediated increase in intracellular Ca2+ concentration via phospholipase C-dependent pathway in porcine aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Benzoquinones; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Estrenes; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lactams, Macrocyclic; Muscle, Smooth, Vascular; Neuropeptide Y; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinones; Receptors, Neuropeptide Y; Rifabutin; Signal Transduction; Swine; Type C Phospholipases | 1995 |
Alpha 2-adrenergic receptors activate phospholipase C in renal epithelial cells.
Topics: Animals; Calcium; Cells, Cultured; Cyclic AMP; Diglycerides; Enzyme Activation; Estrenes; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Kidney Tubules, Distal; Mice; Pyrrolidinones; Receptors, Adrenergic, alpha-2; Type C Phospholipases | 1996 |
Ca2+ signalling mechanisms of the beta 2 integrin on neutrophils: involvement of phospholipase C gamma 2 and Ins(1,4,5)P3.
Topics: Calcium; CD18 Antigens; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Neutrophils; Phosphodiesterase Inhibitors; Phospholipase C gamma; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; Type C Phospholipases | 1996 |
Regulation of blastocoele formation by intracellular calcium release is mediated through a phospholipase C-dependent pathway in mice.
Topics: Animals; Calcium; Calmodulin; Embryonic Development; Enzyme Inhibitors; Estrenes; Ethanol; Female; Inositol 1,4,5-Trisphosphate; Kinetics; Lysophospholipids; Mice; Morula; Phospholipid Ethers; Pregnancy; Protein Kinase C; Pyrrolidinones; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Leukotriene D4-induced Ca2+ mobilization in Ehrlich ascites tumor cells.
Topics: Animals; Calcium; Calcium Channels; Carcinoma, Ehrlich Tumor; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Leukotriene Antagonists; Leukotriene D4; Membrane Proteins; Mice; Pyrrolidinones; Receptors, Leukotriene; Tumor Cells, Cultured; Type C Phospholipases | 1997 |
Involvement of the IP3 cascade in the damage to guinea-pig ventricular myocytes induced by cytotoxic T lymphocytes.
Topics: Animals; Anticoagulants; Electrophysiology; Estrenes; Exudates and Transudates; Fluorescent Dyes; Fura-2; Guinea Pigs; Heart Ventricles; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred BALB C; Myocardium; Phosphodiesterase Inhibitors; Pyrrolidinones; T-Lymphocytes, Cytotoxic | 1997 |
Alpha 1-adrenoceptor activation of a non-selective cation current in rabbit portal vein by 1,2-diacyl-sn-glycerol.
Topics: Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cyclohexanones; Diglycerides; Enzyme Inhibitors; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Lipoprotein Lipase; Norepinephrine; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Portal Vein; Pyrrolidinones; Rabbits; Receptors, Adrenergic, alpha-1; Thionucleotides; Type C Phospholipases | 1997 |
Bitter taste transduction of denatonium in the mudpuppy Necturus maculosus.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylate Cyclase Toxin; Animals; Calcium; Calcium Channels; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Necturus; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pyrrolidinones; Quaternary Ammonium Compounds; Receptors, Cytoplasmic and Nuclear; Ryanodine; Signal Transduction; Taste; Taste Buds; Thapsigargin; Virulence Factors, Bordetella | 1997 |
The effects of bradykinin on K+ currents in NG108-15 cells treated with U73122, a phospholipase C inhibitor, or neomycin.
Topics: Animals; Bradykinin; Calcium; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Mice; Neomycin; Potassium Channels; Pyrrolidinones; Rats; Tumor Cells, Cultured; Type C Phospholipases | 1997 |
Phospholipase C inhibitor, U73122, releases intracellular Ca2+, potentiates Ins(1,4,5)P3-mediated Ca2+ release and directly activates ion channels in mouse pancreatic acinar cells.
Topics: Animals; Calcium; Cell Membrane Permeability; Digitonin; Estrenes; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Ion Channels; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Patch-Clamp Techniques; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Pyrrolidinones; Second Messenger Systems; Type C Phospholipases | 1997 |
Differential induction of inositol phosphate metabolism by three adipokinetic hormones.
Topics: Animals; Energy Metabolism; Estrenes; Fat Body; Flight, Animal; Grasshoppers; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Insect Hormones; Male; Phosphorylases; Pyrrolidinones; Signal Transduction; Type C Phospholipases | 1997 |
Signal transduction pathways associated with contraction during development of the feline gastric antrum.
Topics: Aging; Animals; Animals, Newborn; Calcium; Cats; Cell Movement; Cholecystokinin; Diglycerides; Drug Interactions; Estrenes; Female; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Pyloric Antrum; Pyrrolidinones; Signal Transduction; Time Factors | 1997 |
Mechanisms of bradykinin-induced insulin secretion in clonal beta cell line RINm5F.
Topics: Bradykinin; Calcium; Cell Line; Estrenes; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Islets of Langerhans; NG-Nitroarginine Methyl Ester; Nimodipine; Pertussis Toxin; Pyrrolidinones; Receptors, Bradykinin; Thapsigargin; Virulence Factors, Bordetella | 1997 |
Blockage of urinary responses by inhibitors for IP3-mediated pathway in rat vomeronasal sensory neurons.
Topics: Animals; Enzyme Inhibitors; Estrenes; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Neomycin; Neurons, Afferent; Patch-Clamp Techniques; Pyrrolidinones; Rats; Rats, Wistar; Ruthenium Red; Type C Phospholipases; Urine; Vomeronasal Organ | 1997 |
Bradykinin- and thrombin-induced increases in endothelial permeability occur independently of phospholipase C but require protein kinase C activation.
Topics: Animals; Bradykinin; Calcium; Cattle; Cell Line; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Kinetics; Neomycin; Permeability; Phosphatidylinositols; Protein Kinase C; Pulmonary Artery; Pyrrolidinones; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1997 |
Inhibition of muscarinic-stimulated polyphosphoinositide hydrolysis and Ca2+ mobilization in cat iris sphincter smooth muscle cells by cAMP-elevating agents.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Cats; Cell Fractionation; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Inositol 1,4,5-Trisphosphate; Iris; Isoproterenol; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphodiesterase Inhibitors; Phosphorylation; Pyrrolidinones; Ryanodine; Thapsigargin; Type C Phospholipases | 1997 |
Endothelin-B receptor-mediated Ca2+ signaling in human melanocytes.
Topics: Calcium; Calcium-Transporting ATPases; Cells, Cultured; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Enzyme Activation; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Male; Melanocytes; Peptide Fragments; Peptides, Cyclic; Pyrrolidinones; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Thapsigargin; Type C Phospholipases | 1998 |
Intercellular calcium signaling via gap junction in connexin-43-transfected cells.
Topics: Calcium; Calcium Channels; Cell Line; Connexin 43; Estrenes; Gap Junctions; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mutagenesis, Site-Directed; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Transfection; Type C Phospholipases | 1998 |
Trimethyltin stimulates protein kinase C translocation through receptor-mediated phospholipase C activation in PC12 cells.
Topics: Animals; Atropine; Benzoates; Cell Differentiation; Enzyme Activation; Estrenes; Excitatory Amino Acid Antagonists; Glycine; Inositol 1,4,5-Trisphosphate; Kinetics; Muscarinic Antagonists; PC12 Cells; Protein Kinase C; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Trimethyltin Compounds | 1998 |
The calcium transient in sea urchin eggs during fertilization requires the production of inositol 1,4,5-trisphosphate.
Topics: Animals; Calcium; Cytoplasm; Estrenes; Female; Fertilization; Guanosine 5'-O-(3-Thiotriphosphate); Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Male; Ovum; Pyrrolidinones; Sea Urchins; Sperm-Ovum Interactions; Spermatozoa | 1998 |
Activation of PKC, superoxide anion production and LDL lipid peroxidation are not dependent on phosphoinositide-specific phospholipase C activity in U937 cells.
Topics: Antioxidants; Cell Line; Enzyme Activation; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Lipid Peroxidation; Lipoproteins, LDL; Lithium Chloride; Monocytes; p-Methoxy-N-methylphenethylamine; Phosphatidylinositol Diacylglycerol-Lyase; Protein Kinase C; Pyrrolidinones; Signal Transduction; Superoxides; Type C Phospholipases; Zymosan | 1997 |
Human syncytiotrophoblast NPY receptors are located on BBM and activate PLC-to-PKC axis.
Topics: Adenylyl Cyclases; Arginine; Cell Membrane; Chromones; Enzyme Inhibitors; Estrenes; Female; Humans; Inositol 1,4,5-Trisphosphate; Microvilli; Morpholines; Neuropeptide Y; Peptide YY; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Pregnancy; Protein Kinase C; Pyrrolidinones; Receptors, Neuropeptide Y; Trophoblasts; Type C Phospholipases | 1998 |
Mammalian bombesin receptors are coupled to multiple signal transduction pathways in pancreatic acini.
Topics: Amino Acid Sequence; Aminobenzoates; Amylases; Animals; Bombesin; Chlorobenzoates; Cinnamates; Enzyme Inhibitors; Estrenes; Humans; Hydroxyeicosatetraenoic Acids; Inositol 1,4,5-Trisphosphate; Molecular Sequence Data; Neurokinin B; ortho-Aminobenzoates; Pancreas; Peptide Fragments; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Pyrrolidinones; Radioimmunoassay; Rats; Receptors, Bombesin; Signal Transduction; Structure-Activity Relationship; Swine; Type C Phospholipases | 1998 |
Roles of Ca2+, inositol trisphosphate and cyclic ADP-ribose in mediating intercellular Ca2+ signaling in sheep lens cells.
Topics: Animals; Calcium; Cell Communication; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Gap Junctions; Inositol 1,4,5-Trisphosphate; Ion Transport; Lens, Crystalline; Microinjections; Microscopy, Fluorescence; Phosphatidylinositol Diacylglycerol-Lyase; Poly Adenosine Diphosphate Ribose; Pyrrolidinones; Sheep; Signal Transduction; Type C Phospholipases | 1998 |
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes.
Topics: Animals; Antisense Elements (Genetics); Calcium; Chelating Agents; Chlorides; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Inositol 1,4,5-Trisphosphate; Isoenzymes; Lysophospholipids; Niflumic Acid; Oligonucleotide Probes; Oocytes; Patch-Clamp Techniques; Periodicity; Phospholipase C beta; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; RNA, Messenger; Signal Transduction; Sphingosine; Thapsigargin; Type C Phospholipases; Xenopus laevis | 1998 |
Adrenergic regulation of calcium-activated potassium current in cultured rabbit pigmented ciliary epithelial cells.
Topics: Adrenergic alpha-Agonists; Animals; Calcium-Transporting ATPases; Cells, Cultured; Ciliary Body; Enzyme Inhibitors; Epinephrine; Epithelial Cells; Estrenes; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Ionomycin; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Peptides; Phenylephrine; Potassium Channels; Potassium Channels, Calcium-Activated; Prazosin; Pyrrolidinones; Rabbits; Receptors, Adrenergic, alpha-1; Scorpion Venoms; Signal Transduction; Tetraethylammonium; Thapsigargin; Type C Phospholipases | 1998 |
P2Y and P2U receptors differentially release intracellular Ca2+ via the phospholipase c/inositol 1,4,5-triphosphate pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Channels; Cells, Cultured; Embryo, Mammalian; Estrenes; GTP-Binding Proteins; Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Spinal Cord; Thionucleotides; Type C Phospholipases; Uridine Triphosphate | 1998 |
Magnolol induces cytosolic-free Ca2+ elevation in rat neutrophils primarily via inositol trisphosphate signalling pathway.
Topics: Animals; Biphenyl Compounds; Calcium; Cytosol; Estrenes; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate; Lignans; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrrolidinones; Rats; Ryanodine; Signal Transduction | 1998 |
Bradykinin causes contraction in rat uterus through the same signal pathway as oxytocin.
Topics: Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Estrenes; Female; Imidazoles; Inositol 1,4,5-Trisphosphate; Myometrium; Oxytocin; Phosphodiesterase Inhibitors; Potassium Chloride; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Uterine Contraction | 1998 |
In vivo signal transduction of tetrodotoxin-sensitive nociceptive responses by substance P given into the planta of the mouse hind limb.
Topics: Action Potentials; Afferent Pathways; Animals; Biphenyl Compounds; Calcium Signaling; Egtazic Acid; Estrenes; GTP-Binding Proteins; Hindlimb; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Mice; Mice, Inbred Strains; Models, Neurological; Muscle Contraction; Neurons, Afferent; Neurotoxins; Nociceptors; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Neurokinin-1; Reflex; Signal Transduction; Substance P; Tetrodotoxin; Type C Phospholipases | 1998 |
Calcium signalling through nucleotide receptor P2Y2 in cultured human vascular endothelium.
Topics: Adenosine Triphosphate; Calcium; Calcium Signaling; Cells, Cultured; Endothelium, Vascular; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Manganese; Nickel; Nitrobenzoates; Nucleotides; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Type C Phospholipases; Uridine Triphosphate | 1998 |
Sphingosylphosphorylcholine stimulates mitogen-activated protein kinase via a Ca2+-dependent pathway.
Topics: Adenosine Triphosphate; Animals; Aorta; Bradykinin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cells, Cultured; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Kinetics; Lysophospholipids; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphorylcholine; Platelet-Derived Growth Factor; Protein Kinase C; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Swine; Thapsigargin; Virulence Factors, Bordetella | 1998 |
A1 adenosine receptor-mediated Ins(1,4,5)P3 generation in allergic rabbit airway smooth muscle.
Topics: Adenosine; Airway Resistance; Allergens; Animals; Asthma; Bronchi; Dust; Estrenes; Immunoglobulin E; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lung Compliance; Mites; Muscle Contraction; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrrolidinones; Rabbits; Receptors, Purinergic P1; Respiratory Hypersensitivity | 1998 |
Evidence for separate effects of U73122 on phospholipase C and calcium channels in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Calcium; Calcium Channels; Cytosol; Enzyme Activation; Estrenes; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Manganese; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrrolidinones; Type C Phospholipases | 1998 |
1alpha,25-dihydroxy-vitamin-D3-induced store-operated Ca2+ influx in skeletal muscle cells. Modulation by phospholipase c, protein kinase c, and tyrosine kinases.
Topics: Animals; Calcitriol; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Kinetics; Manganese; Muscle, Skeletal; Neomycin; Nifedipine; Phosphatidylinositol Diacylglycerol-Lyase; Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Thapsigargin; Type C Phospholipases; Verapamil | 1998 |
Cell-specific signaling and structure-activity relations of parathyroid hormone analogs in mouse kidney cells.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Calcium; Cells, Cultured; Diglycerides; Enzyme Activation; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kidney Tubules, Distal; Kidney Tubules, Proximal; Mice; Parathyroid Hormone; Peptide Fragments; Phosphodiesterase Inhibitors; Phospholipase C beta; Protein Kinase C; Pyrrolidinones; Receptor, Parathyroid Hormone, Type 1; Receptors, Parathyroid Hormone; Signal Transduction; Structure-Activity Relationship; Type C Phospholipases | 1999 |
Real-time visualization of PH domain-dependent translocation of phospholipase C-delta1 in renal epithelial cells (MDCK): response to hypo-osmotic stress.
Topics: Animals; Calcium; Catalytic Domain; Cell Line; Cell Membrane; Cytosol; Dogs; Enzyme Inhibitors; Epithelial Cells; Estrenes; Green Fluorescent Proteins; Hypotonic Solutions; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kidney; Kinetics; Luminescent Proteins; Phospholipase C delta; Pyrrolidinones; Recombinant Fusion Proteins; src Homology Domains; Substrate Specificity; Time Factors; Transfection; Type C Phospholipases | 1999 |
Multiple effects of econazole on calcium signaling: depletion of thapsigargin-sensitive calcium store, activation of extracellular calcium influx, and inhibition of capacitative calcium entry.
Topics: Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Line; Dogs; Econazole; Enzyme Inhibitors; Estrenes; Extracellular Space; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lanthanum; Pyrrolidinones; Thapsigargin; Type C Phospholipases | 1999 |
17beta-oestradiol increases intracellular Ca2+ concentration in rat enterocytes. Potential role of phospholipase C-dependent store-operated Ca2+ influx.
Topics: Animals; Calcium; Cells, Cultured; Diglycerides; Duodenum; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrenes; Female; Inositol 1,4,5-Trisphosphate; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Type C Phospholipases | 1999 |
Lipoprotein(a) stimulates growth of human mesangial cells and induces activation of phospholipase C via pertussis toxin-sensitive G proteins.
Topics: Blood Proteins; Calcium; Cell Division; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Estrenes; Glomerular Mesangium; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lipoprotein(a); Pertussis Toxin; Phosphodiesterase Inhibitors; Pyrrolidinones; Type C Phospholipases; Vasopressins; Virulence Factors, Bordetella | 1999 |
The mechanism mediating regenerative intercellular Ca2+ waves in the blowfly salivary gland.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Diffusion; Diptera; Enzyme Activation; Estrenes; Feedback; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Microinjections; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; Salivary Glands; Serotonin; Serotonin Antagonists; Thapsigargin; Time Factors; Type C Phospholipases | 1999 |
Calcium release from InsP3-sensitive internal stores initiates action potential in Chara.
Topics: Calcium; Calcium Channel Blockers; Chlorophyta; Electric Conductivity; Estrenes; Inositol 1,4,5-Trisphosphate; Lanthanum; Membrane Potentials; Models, Biological; Neomycin; Pyrrolidinones; Ryanodine; Type C Phospholipases | 1999 |
Relationship between inositol 1,4,5-trisphosphate receptor isoforms and subcellular Ca2+ signaling patterns in nonpigmented ciliary epithelia.
Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Ciliary Body; Epithelial Cells; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; Microscopy, Confocal; Pigment Epithelium of Eye; Protein Isoforms; Pyrrolidinones; Rabbits; Receptor, Muscarinic M3; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1999 |
Inositol 1,4,5-trisphosphate-independent Ca(2+) mobilization triggered by a lipid factor isolated from vitreous body.
Topics: 3T3 Cells; Animals; Calcium; Cattle; Cell Line; Estrenes; Ethylmaleimide; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Mice; Phospholipids; Pyrrolidinones; Signal Transduction; Vitreous Body | 1999 |
IP(3)-Independent release of Ca(2+) from intracellular stores: A novel mechanism for transduction of bitter stimuli.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dextromethorphan; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Models, Neurological; Necturus; Pyrrolidinones; Ryanodine; Signal Transduction; Sulfonamides; Taste; Taste Buds; Thapsigargin; Thionucleotides; Type C Phospholipases | 1999 |
Urokinase receptor (CD87) aggregation triggers phosphoinositide hydrolysis and intracellular calcium mobilization in mononuclear phagocytes.
Topics: Benzoquinones; Calcium Signaling; Cell Adhesion; Cell Movement; Estrenes; Humans; Hydrolysis; Immunologic Capping; Inositol 1,4,5-Trisphosphate; Lactams, Macrocyclic; Leukotriene B4; Macrophage-1 Antigen; Monocytes; Phosphatidylinositols; Protein-Tyrosine Kinases; Pyrrolidinones; Quinones; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Rifabutin; Thapsigargin; Type C Phospholipases; U937 Cells | 1999 |
Mechanisms of miconazole-induced rise in cytoplasmic calcium concentrations in Madin Darby canine kidney (MDCK) cells.
Topics: Animals; Calcium; Calcium Signaling; Cations; Cell Line; Cytoplasm; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Endoplasmic Reticulum; Estrenes; Inositol 1,4,5-Trisphosphate; Kidney; Lanthanum; Miconazole; Phosphodiesterase Inhibitors; Pyrrolidinones; Thapsigargin; Type C Phospholipases | 1999 |
Regulation of calcium signalling by docosahexaenoic acid in human T-cells. Implication of CRAC channels.
Topics: Antibodies; Calcium; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; CD3 Complex; Cell Division; Docosahexaenoic Acids; Enzyme Inhibitors; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Jurkat Cells; Membrane Potentials; Pyrrolidinones; T-Lymphocytes; Thapsigargin | 2000 |
Mechanisms of AVP-induced glucagon release in clonal alpha-cells in-R1-G9: involvement of Ca(2+)-dependent and -independent pathways.
Topics: Amino Acid Chloromethyl Ketones; Animals; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Clone Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Estrenes; Glucagon; Inositol 1,4,5-Trisphosphate; Nimodipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Renal Agents; Serine Proteinase Inhibitors; Thapsigargin | 2000 |
Effect of erythromycin on ATP-induced intracellular calcium response in A549 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Anti-Bacterial Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Erythromycin; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Lung; Nickel; Potassium Chloride; Protein Isoforms; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tumor Cells, Cultured; Uridine Triphosphate; Verapamil | 2000 |
Cyclosporin-A-induced effects on the free Ca2+ concentration in LLC-PK1-cells and their mechanisms.
Topics: Adenosine Triphosphate; Animals; Arginine Vasopressin; Biological Transport; Calcineurin Inhibitors; Calcium; Cyclosporine; Estrenes; Fluorescent Dyes; Fura-2; Immunosuppressive Agents; Inositol 1,4,5-Trisphosphate; Kidney Tubules, Proximal; LLC-PK1 Cells; Nicardipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Renal Agents; Signal Transduction; Swine; Tacrolimus; Type C Phospholipases; Vasodilator Agents | 2000 |
Characterization and functional significance of calcium transients in the 2-cell mouse embryo induced by an autocrine growth factor.
Topics: Animals; Autocrine Communication; Blastocyst; Calcium; Estrenes; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Mice; Oxazoles; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyrrolidinones | 2000 |
Novel effects of propranolol. Release of internal Ca(2+) followed by activation of capacitative Ca(2+) entry in Madin Darby canine kidney cells.
Topics: Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Line; Cytosol; Dogs; Estrenes; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kidney; Kinetics; Neutrophils; Phosphodiesterase Inhibitors; Propranolol; Pyrrolidinones; Signal Transduction; Thapsigargin | 2000 |
Calcium transient activity in cultured murine neural crest cells is regulated at the IP(3) receptor.
Topics: Animals; Antifungal Agents; Biological Transport; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Central Nervous System Stimulants; Enzyme Inhibitors; Estrenes; Extracellular Space; Fetus; Hydroquinones; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Lanthanum; Magnesium; Mice; Neural Crest; Neurons; Phosphodiesterase Inhibitors; Phospholipase C gamma; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thimerosal; Type C Phospholipases | 2000 |
Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.
Topics: Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Immunologic; Estrenes; Gene Products, tat; HIV-1; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Macrophages; Pertussis Toxin; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; tat Gene Products, Human Immunodeficiency Virus; Time Factors; Tumor Necrosis Factor-alpha; Type C Phospholipases; Virulence Factors, Bordetella | 2000 |
Identification of possible signal transduction components mediating light induction of the Gsa gene for an early chlorophyll biosynthetic step in Chlamydomonas reinhardtii.
Topics: Animals; Benzylamines; Blotting, Northern; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Chlamydomonas reinhardtii; Chlorophyll; Cyclosporine; Darkness; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; Intramolecular Transferases; Light; Peptides; Pyrrolidinones; Sulfonamides; Type C Phospholipases | 2000 |
Cross-talk between olfactory second messenger pathways.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cilia; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Imines; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; Olfactory Pathways; Peptides; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Second Messenger Systems; Type C Phospholipases | 2000 |
Sevoflurane stimulates inositol 1,4,5-trisphosphate in skeletal muscle.
Topics: Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Genistein; GTP-Binding Proteins; Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Methyl Ethers; Muscle, Skeletal; ortho-Aminobenzoates; Phospholipases A; Protein-Tyrosine Kinases; Pyrrolidinones; Rats; Sevoflurane; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases; Tyrphostins | 2000 |
Role of the phosphatidylinositol-specific phospholipase C pathway in delta-opioid receptor-mediated antinociception in the mouse spinal cord.
Topics: Analgesics; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Estrenes; Indoles; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred ICR; Naphthalenes; Oligopeptides; Pain; Pain Measurement; Phosphatidylinositols; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptors, Opioid, delta; Signal Transduction; Spinal Cord; Type C Phospholipases | 2000 |
Calcium-dependent activation of phospholipase C by mechanical distension in renin-expressing As4.1 cells.
Topics: Animals; Calcium; Cell Line; Cytosol; Enzyme Activation; Estrenes; Extracellular Space; Fluorescent Dyes; Fura-2; Gadolinium; Inositol; Inositol 1,4,5-Trisphosphate; Ion Channels; Kidney; Mice; Mice, Transgenic; Phosphodiesterase Inhibitors; Pyrrolidinones; Renin; Ryanodine; Second Messenger Systems; Signal Transduction; Stress, Mechanical; Type C Phospholipases | 2000 |
Modulation of phospholipase C pathway in rat cerebral cortex during aging.
Topics: Aging; Animals; Cell Membrane; Cerebral Cortex; Enzyme Inhibitors; Estrenes; GTP Phosphohydrolases; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Phospholipase C beta; Protein Subunits; Pyrrolidinones; Rats; Rats, Wistar; Type C Phospholipases | 2000 |
PTH and PTH-related peptide enhance steroid secretion from human adrenocortical cells.
Topics: Adenine; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Cyclic AMP; Enzyme Inhibitors; Estrenes; Humans; Hydrocortisone; Inositol 1,4,5-Trisphosphate; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Proteins; Pyrrolidinones | 2001 |
Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cells, Cultured; Cycloleucine; Estrenes; Extracellular Space; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Neomycin; Neuroprotective Agents; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Mechanical; Type C Phospholipases | 2001 |
Fluoxetine-induced Ca2+ signals in Madin-Darby canine kidney cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cell Line; Dogs; Endoplasmic Reticulum; Estrenes; Fluoxetine; Humans; Inositol 1,4,5-Trisphosphate; Kidney; Neutrophils; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Thapsigargin; Time Factors; Tumor Cells, Cultured | 2001 |
Hyperosmotic stress induces a rapid and transient increase in inositol 1,4,5-trisphosphate independent of abscisic acid in Arabidopsis cell culture.
Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Calcium-Binding Proteins; Cells, Cultured; Enzyme Inhibitors; Estrenes; Gene Expression; Genes, Plant; Inositol 1,4,5-Trisphosphate; Neomycin; Osmotic Pressure; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Pyrrolidinones; Time Factors; Transcription Factors; Type C Phospholipases | 2001 |
Characterization of intracellular calcium oscillations induced by extracellular nucleotides in HEp-2 cells.
Topics: Adenosine Triphosphate; Aniline Compounds; Calcium Signaling; Cell Line; Enzyme Inhibitors; Estrenes; Extracellular Space; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Microscopy, Confocal; Protein Kinase C; Pyrrolidinones; Ryanodine; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Uridine Triphosphate; Xanthenes | 2000 |
A role for inositol 1,4,5-trisphosphate in gravitropic signaling and the retention of cold-perceived gravistimulation of oat shoot pulvini.
Topics: Avena; Cold Temperature; Enzyme Inhibitors; Estrenes; Gravitropism; Inositol 1,4,5-Trisphosphate; Plant Shoots; Pyrrolidinones; Signal Transduction; Type C Phospholipases | 2001 |
U73122 inhibits the dephosphorylation and translocation of cofilin in activated macrophage-like U937 cells.
Topics: Actin Depolymerizing Factors; Cell Membrane; Estrenes; HL-60 Cells; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Macrophage Activation; Microfilament Proteins; Opsonin Proteins; Phosphorylation; Protein Transport; Pyrrolidinones; src-Family Kinases; Superoxides; Type C Phospholipases; U937 Cells; Zymosan | 2001 |
Role of the phospholipase C-inositol 1,4,5-trisphosphate pathway in calcium release-activated calcium current and capacitative calcium entry.
Topics: Androstadienes; Animals; B-Lymphocytes; Boron Compounds; Calcium; Calcium Channels; Cell Line, Transformed; Cells, Cultured; Chickens; Enzyme Inhibitors; Estrenes; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Lacrimal Apparatus; Leukemia, Basophilic, Acute; Mice; Phosphatidylinositol Phosphates; Pyrrolidinones; Rats; Receptors, Cytoplasmic and Nuclear; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Wortmannin | 2001 |
Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.
Topics: Bacterial Proteins; Bacterial Toxins; Cell Line; Cell Membrane; Dimerization; Enzyme Inhibitors; Estrenes; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Maleimides; Membrane Potentials; Pasteurella multocida; Phorbol Esters; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Subunits; Pyrrolidinones; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Serotonin; Thyrotropin-Releasing Hormone; Transfection; Type C Phospholipases | 2001 |
Sperm factor induces intracellular free calcium oscillations by stimulating the phosphoinositide pathway.
Topics: Adenosine; Alternative Splicing; Animals; Biological Factors; Blotting, Western; Calcium; Calcium Chloride; Cytosol; Enzyme Activation; Enzyme Inhibitors; Estrenes; Female; Inositol 1,4,5-Trisphosphate; Isoenzymes; Male; Microinjections; Oocytes; Phosphatidylinositols; Pyrrolidinones; Semen; Swine; Testis; Tissue Extracts; Type C Phospholipases; Xenopus | 2001 |
Clomiphene, an ovulation-inducing agent, mobilizes intracellular Ca2+ and causes extracellular Ca2+ influx in bladder female transitional carcinoma cells.
Topics: Calcium; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinoma, Transitional Cell; Clomiphene; Cytosol; Enzyme Inhibitors; Estrenes; Female; Golgi Apparatus; Humans; Inositol 1,4,5-Trisphosphate; Ovulation Induction; Pyrrolidinones; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Uncoupling Agents; Urinary Bladder Neoplasms | 2000 |
Synergistic effects of ATP on oxytocin-induced intracellular Ca2+ response in mouse mammary myoepithelial cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Epithelial Cells; Estrenes; Female; Fura-2; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Lactation; Mammary Glands, Animal; Mice; Mice, Inbred ICR; Oxytocin; Pertussis Toxin; Pyrrolidinones; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Effect of fluoxetine on intracellular Ca2+ levels in bladder female transitional carcinoma (BFTC) cells.
Topics: Calcium; Carcinoma, Transitional Cell; Cell Line; Estrenes; Female; Fluoxetine; Humans; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2001 |
Miniature postsynaptic currents depend on Ca2+ released from internal stores via PLC/IP3 pathway.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Long-Evans; Receptors, Cytoplasmic and Nuclear; Retinal Ganglion Cells; Thapsigargin; Type C Phospholipases | 2001 |
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Pertussis Toxin; Phospholipases; Pinealoma; Pyrrolidinones; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
Fendiline mobilizes intracellular Ca2+ in Chang liver cells.
Topics: Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Dose-Response Relationship, Drug; Estrenes; Fendiline; Humans; Imidazoles; Inositol 1,4,5-Trisphosphate; Liver; Phosphodiesterase Inhibitors; Pyrrolidinones; Thapsigargin; Time Factors; Type C Phospholipases | 2001 |
CP55,940 increases intracellular Ca2+ levels in Madin-Darby canine kidney cells.
Topics: Animals; Calcium; Cannabinoids; Cell Line; Cyclohexanols; Dogs; Estrenes; Extracellular Space; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Kidney; Morpholines; Piperidines; Pyrazoles; Pyrrolidinones; Receptors, Cannabinoid; Receptors, Drug | 2001 |
Activation of inositol 1,4,5-trisphosphate receptor is essential for the opening of mouse TRP5 channels.
Topics: Acetylcholine; Adenosine; Allosteric Regulation; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Cation Transport Proteins; Electrophysiology; Estrenes; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Mice; Nuclear Proteins; Oligodeoxyribonucleotides, Antisense; Oocytes; Oxazoles; Peptides; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Pyrrolidinones; Receptor, Muscarinic M1; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; TRPC Cation Channels; Type C Phospholipases; Xenopus laevis | 2001 |
Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein.
Topics: beta-Defensins; Caco-2 Cells; Calcium; Cell Nucleus; Chelating Agents; Colon; Culture Media; Egtazic Acid; Estrenes; Flagellin; Heparin; Humans; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; NF-kappa B; Pertussis Toxin; Promoter Regions, Genetic; Pyrrolidinones; RNA, Messenger; Salmonella enteritidis; Signal Transduction; Up-Regulation; Virulence Factors, Bordetella | 2001 |
Mechanism underlying histamine-induced intracellular Ca2+ movement in PC3 human prostate cancer cells.
Topics: Calcium; Calcium-Transporting ATPases; Endoplasmic Reticulum; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Phosphodiesterase Inhibitors; Prostatic Neoplasms; Pyrilamine; Pyrrolidinones; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases | 2001 |
Effect of 17beta-estradiol on intracellular Ca(2+) levels in renal tubular cells.
Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Ion Transport; Ionophores; Kidney Tubules; Macrolides; Male; Pyrrolidinones; Thapsigargin; Tumor Cells, Cultured; Uncoupling Agents | 2002 |
mAChRs in the grasshopper brain mediate excitation by activation of the AC/PKA and the PLC second-messenger pathways.
Topics: Acetylcholine; Adenine; Adenylyl Cyclases; Animal Communication; Animals; Brain; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dideoxyadenosine; Diglycerides; Enzyme Inhibitors; Estrenes; Grasshoppers; Inositol 1,4,5-Trisphosphate; Isoquinolines; Muscarine; Muscarinic Agonists; Phosphodiesterase Inhibitors; Purinones; Pyrrolidinones; Receptors, Muscarinic; Second Messenger Systems; Sphingosine; Sulfonamides; Thapsigargin; Thionucleotides; Type C Phospholipases | 2002 |
Inositol 1,4,5-trisphosphate transduction cascade in taste reception of the fleshfly, Boettcherisca peregrina.
Topics: Adenosine; Animals; Animals, Genetically Modified; Calcium Channel Agonists; Calcium Channels; Deoxycholic Acid; Detergents; Diptera; Drosophila melanogaster; Drosophila Proteins; Estrenes; Gene Expression; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Heterotrimeric GTP-Binding Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Neomycin; Nerve Tissue Proteins; Paired Box Transcription Factors; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phospholipase C beta; Protein Synthesis Inhibitors; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; Ruthenium Red; Signal Transduction; Taste; Transcription Factors; Type C Phospholipases | 2002 |
Involvement of phosphoinositide turnover in tracheary element differentiation in Zinnia elegans L. cells.
Topics: Asteraceae; Calcium; Cell Differentiation; Estrenes; Inositol 1,4,5-Trisphosphate; Pertussis Toxin; Phosphatidylinositols; Plant Structures; Pyrrolidinones; Type C Phospholipases; Virulence Factors, Bordetella | 2002 |
ATP-inhibition of M current in frog sympathetic neurons involves phospholipase C but not Ins P(3), Ca(2+), PKC, or Ras.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channels; Culture Techniques; Electric Conductivity; Enzyme Inhibitors; Estrenes; Female; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Membranes; Male; Neural Inhibition; Neurons; Phenanthridines; Protein Kinase C; Pyrrolidinones; Rana catesbeiana; ras Proteins; Receptors, Cytoplasmic and Nuclear; Sympathetic Nervous System; Thapsigargin; Type C Phospholipases | 2002 |
Calcium mobilization evoked by hepatocellular swelling is linked to activation of phospholipase Cgamma.
Topics: Animals; Calcium; Calcium Channels; Cell Size; Enzyme Activation; Estrenes; Hepatocytes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Phospholipase C gamma; Phosphorylation; Pyrrolidinones; Rats; Receptors, Cytoplasmic and Nuclear; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Differential activation of ion channels by inositol 1,4,5-trisphosphate (IP3)- and ryanodine-sensitive calcium stores in rat basilar artery vasomotion.
Topics: Animals; Basilar Artery; Calcium; Calcium Channels; Calcium-Transporting ATPases; Charybdotoxin; Chloride Channels; Electrophysiology; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ion Channels; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Pyrrolidinones; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Type C Phospholipases | 2002 |
Vortex-mediated mechanical stress induces integrin-dependent cell adhesion mediated by inositol 1,4,5-trisphosphate-sensitive Ca2+ release in THP-1 cells.
Topics: Calcium; Calmodulin; Cell Adhesion; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Fibronectins; Humans; Inositol 1,4,5-Trisphosphate; Integrin beta1; Integrins; Monocytes; Pyrrolidinones; Stress, Mechanical; Sulfonamides; Time Factors | 2003 |
Involvement of G(q/11) in signal transduction in the mammalian vomeronasal organ.
Topics: Animals; Blotting, Western; Estrenes; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Immunoenzyme Techniques; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Mice; Pertussis Toxin; Pheromones; Pyrrolidinones; Signal Transduction; Type C Phospholipases; Urine; Vomeronasal Organ | 2003 |
The phospholipase C-IP3 pathway is involved in muscarinic antinociception.
Topics: Analgesics; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Estrenes; Inositol 1,4,5-Trisphosphate; Male; Mice; Pain Measurement; Physostigmine; Pyrrolidinones; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 2003 |
Is Ca2+ release from internal stores involved in membrane excitation in characean cells?
Topics: Boron Compounds; Calcium; Cell Membrane; Chlorophyta; Cytoplasmic Streaming; Electric Conductivity; Estrenes; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Neomycin; Pyrrolidinones; Type C Phospholipases | 2003 |
Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA.
Topics: Amino Acid Motifs; Animals; Antigens, CD; Blood Platelets; Blotting, Western; Calcium; Cell Adhesion; CHO Cells; Cricetinae; Cytoskeleton; Cytosol; Enzyme Inhibitors; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred C57BL; Phospholipase C gamma; Phosphorylation; Platelet Glycoprotein GPIb-IX Complex; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Pyrrolidinones; Receptors, IgG; Signal Transduction; Time Factors; Type C Phospholipases | 2003 |
Hg2+ signaling in trout hepatoma (RTH-149) cells: involvement of Ca2+-induced Ca2+ release.
Topics: Aniline Compounds; Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Signaling; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosol; Estrenes; Ethylenediamines; Glutathione; GTP-Binding Proteins; Guanosine Diphosphate; Heparin; Histocytochemistry; Inositol 1,4,5-Trisphosphate; Kinetics; Mercury; Microscopy, Confocal; Microscopy, Fluorescence; Phospholipases; Pyrrolidinones; Thionucleotides; Trout; Verapamil; Xanthenes | 2003 |
The G-protein-coupled receptor GCR1 regulates DNA synthesis through activation of phosphatidylinositol-specific phospholipase C.
Topics: Arabidopsis Proteins; Cloning, Molecular; DNA Replication; DNA, Plant; Enzyme Activation; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Models, Biological; Nicotiana; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphorylation; Protein Kinase C; Pyrrolidinones; Receptors, G-Protein-Coupled; Recombinant Proteins; Signal Transduction; Thymidine; Transcription Factors | 2003 |
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Aristolochic Acids; Bridged-Ring Compounds; Caffeine; Calcium; Carbachol; Diglycerides; Estrenes; Guanosine Triphosphate; Guinea Pigs; Ileum; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoenzymes; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth; Norbornanes; Patch-Clamp Techniques; Phospholipase C beta; Phospholipases A; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ryanodine; Thiocarbamates; Thiones; Type C Phospholipases | 2004 |
Calcineurin phosphatase activity: activation by glucocorticoids and role of intracellular calcium.
Topics: Annexin A5; Calcium; Dactinomycin; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gene Expression Regulation, Enzymologic; Glucocorticoids; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Kinetics; Mifepristone; Phosphoric Monoester Hydrolases; Pyrrolidinones; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Type C Phospholipases | 2004 |
Novel role of phospholipase C-delta1: regulation of liver mitochondrial Ca2+ uptake.
Topics: Adenosine; Animals; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium Channels; Calcium-Binding Proteins; Cell Membrane; Estrenes; Fluorescent Dyes; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoenzymes; Male; Microscopy, Fluorescence; Mitochondria, Liver; Phosphodiesterase Inhibitors; Phospholipase C delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Spermine; Stimulation, Chemical; Type C Phospholipases | 2004 |
The phospholipase C-InsP3 pathway is involved in calcium mobilization induced by growth hormone in hepatocytes.
Topics: Animals; Calcium; Cattle; Cytosol; Enzyme Inhibitors; Estrenes; Growth Hormone; Hepatocytes; Inositol 1,4,5-Trisphosphate; Male; Oscillometry; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Type C Phospholipases | 2004 |
Depolarization of skeletal muscle cells induces phosphorylation of cAMP response element binding protein via calcium and protein kinase Calpha.
Topics: Active Transport, Cell Nucleus; Animals; Animals, Newborn; Blotting, Western; Cell Line; Cell Nucleus; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Estrenes; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phorbol Esters; Phosphorylation; Potassium; Precipitin Tests; Protein Isoforms; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2004 |
Effect of carvedilol on Ca2+ movement and cytotoxicity in human MG63 osteosarcoma cells.
Topics: Adenylyl Cyclases; Calcium; Calcium Channels; Calcium Signaling; Carbazoles; Carvedilol; Cell Compartmentation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colforsin; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Estrenes; Fluorescence; Fura-2; Histamine; Histamine Antagonists; Humans; Inositol 1,4,5-Trisphosphate; Manganese; Osteosarcoma; Phorbol Esters; Propanolamines; Protein Kinase C; Pyrrolidinones; Tetrazolium Salts; Thapsigargin; Time Factors; Type C Phospholipases | 2004 |
Involvement of phospholipase C in Yersinia enterocolitica heat stable enterotoxin (Y-STa) mediated rise in intracellular calcium level in rat intestinal epithelial cells.
Topics: Animals; Bacterial Toxins; Boron Compounds; Calcium; Calcium Channels; Cells, Cultured; Dantrolene; Enterotoxins; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intestinal Mucosa; Male; Pyrrolidinones; Rats; Receptors, Cytoplasmic and Nuclear; Time Factors; Type C Phospholipases; Yersinia enterocolitica | 2005 |
Evidence for signaling via gap junctions from smooth muscle to endothelial cells in rat mesenteric arteries: possible implication of a second messenger.
Topics: Animals; Boron Compounds; Calcium; Calcium Signaling; Endothelial Cells; Enzyme Inhibitors; Estrenes; Fatty Acids, Monounsaturated; Fura-2; Gap Junctions; Inositol 1,4,5-Trisphosphate; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Pyrrolidinones; Rats; Rats, Wistar; Second Messenger Systems; Type C Phospholipases | 2005 |
Involvement of phospholipase C and intracellular calcium signaling in the gonadotropin-releasing hormone regulation of prolactin release from lactotrophs of tilapia (Oreochromis mossambicus).
Topics: Animals; Calcium; Calcium Signaling; Estrenes; Gallic Acid; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Male; Pituitary Gland; Platelet Aggregation Inhibitors; Prolactin; Pyrrolidinones; Tilapia; Type C Phospholipases | 2005 |
Strontium promotes calcium oscillations in mouse meiotic oocytes and early embryos through InsP3 receptors, and requires activation of phospholipase and the synergistic action of InsP3.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Drug Synergism; Embryo, Mammalian; Embryonic Development; Enzyme Activation; Estrenes; Female; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; Meiosis; Mice; Oocytes; Parthenogenesis; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; Spermatozoa; Strontium; Type C Phospholipases | 2005 |
Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Compartmentation; Estrenes; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Isoenzymes; NADP; Nimodipine; Pyrrolidinones; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thrombin; Type C Phospholipases; Vasopressins | 2006 |
Rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands.
Topics: Adenylyl Cyclases; Animals; Arylalkylamine N-Acetyltransferase; Blotting, Northern; Bradykinin; Calcium; Chelating Agents; Circadian Rhythm; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Gene Expression Regulation, Enzymologic; Immunoblotting; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Isoproterenol; Male; Melatonin; Norepinephrine; Pertussis Toxin; Phosphodiesterase Inhibitors; Pineal Gland; Protein Isoforms; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Superior Cervical Ganglion; Time Factors; Transcriptional Activation; Type C Phospholipases | 2005 |
Similar mechanisms regulate protein exocytosis from the salivary glands of ixodid and argasid ticks.
Topics: Animals; Apyrase; Calcium; Calcium Channels, L-Type; Dinoprostone; Dopamine; Estrenes; Exocytosis; Inositol 1,4,5-Trisphosphate; Pyrrolidinones; Salivary Glands; Signal Transduction; Sodium-Potassium-Exchanging ATPase; South Africa; Species Specificity; Ticks; Type C Phospholipases | 2005 |
Intraplatelet signaling mechanisms of the priming effect of matrix metalloproteinase-2 on platelet aggregation.
Topics: Androstadienes; Blood Platelets; Calcium; Chromones; Drug Synergism; Estrenes; Humans; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Protein Kinase C; Pyrrolidinones; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Thrombin; Tissue Inhibitor of Metalloproteinase-2; Type C Phospholipases; Wortmannin | 2005 |
Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes.
Topics: Adenoviridae; Albumins; Aniline Compounds; Animals; Animals, Newborn; Apoptosis; Calcium; Cells, Cultured; Estrenes; Fluorescent Dyes; Genetic Vectors; Image Processing, Computer-Assisted; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Microscopy, Fluorescence; Models, Statistical; Myocytes, Cardiac; Peptides; Pertussis Toxin; Pyrrolidinones; Rats; Signal Transduction; Testosterone; Thapsigargin; Type C Phospholipases; Xanthenes | 2006 |
Critical role of phospholipase Cgamma1 in the generation of H2O2-evoked [Ca2+]i oscillations in cultured rat cortical astrocytes.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Estrenes; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Phospholipase C gamma; Pyrrolidinones; Rats; Rats, Wistar; Thapsigargin | 2006 |
Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22.
Topics: Acetophenones; Benzopyrans; Calcium; Calcium Channels; Calcium Signaling; Catalytic Domain; Cell Line, Tumor; Chemokine CCL17; Chemokine CCL22; Chemokines, CC; Chemotaxis; Chromones; Diglycerides; Estrenes; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Leukemia-Lymphoma, Adult T-Cell; Morpholines; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphothreonine; Protein Processing, Post-Translational; Pyrroles; Pyrrolidinones; Receptors, CCR4; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; T-Lymphocytes; Th2 Cells | 2006 |
Primary evidence for involvement of IP3 in heat-shock signal transduction in Arabidopsis.
Topics: Aequorin; Apoproteins; Arabidopsis; Arabidopsis Proteins; Calcium; Cells, Cultured; Estrenes; Gene Expression Regulation, Plant; Glucuronidase; Heat-Shock Proteins; Heat-Shock Response; Hot Temperature; Inositol 1,4,5-Trisphosphate; Intracellular Calcium-Sensing Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Pyrrolidinones; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Type C Phospholipases | 2006 |
Role of phospholipase C-gamma in NGF-stimulated differentiation and gene induction.
Topics: Animals; Cell Differentiation; Estrenes; Gene Expression Regulation; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Nerve Growth Factor; Neurons; Oxazoles; PC12 Cells; Phosphodiesterase Inhibitors; Phospholipase C gamma; Pyrrolidinones; Rats; Signal Transduction; Transcriptional Activation | 2006 |
Cell cycle-dependent calcium oscillations in mouse embryonic stem cells.
Topics: Adenosine Triphosphatases; Animals; Boron Compounds; Calcium; Calcium Signaling; Cell Cycle; Cells, Cultured; Chelating Agents; Egtazic Acid; Embryonic Stem Cells; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Protein Isoforms; Pyrrolidinones; Thapsigargin; Type C Phospholipases | 2007 |
Two distinct signaling pathways for regulation of spontaneous local Ca2+ release by phospholipase C in airway smooth muscle cells.
Topics: Alkaloids; Animals; Benzophenanthridines; Boron Compounds; Caffeine; Calcium; Cells, Cultured; Diglycerides; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Male; Mice; Myocytes, Smooth Muscle; Oxazoles; Pyrrolidinones; Respiratory System; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Type C Phospholipases | 2007 |
Suprasternal gland secretion of male short-tailed opossum induces IP3 generation in the vomeronasal organ.
Topics: Animals; Estrenes; GTP-Binding Protein alpha Subunits, Gi-Go; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Male; Monodelphis; Olfactory Mucosa; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Odorant; Scent Glands; Second Messenger Systems; Sex Attractants; Signal Transduction; Suramin; Type C Phospholipases; Vomeronasal Organ | 2007 |
Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells.
Topics: Astrocytoma; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Estrenes; Extracellular Signal-Regulated MAP Kinases; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Methionine; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Pyrrolidinones; Receptor Protein-Tyrosine Kinases; Receptor, Endothelin B; Signal Transduction | 2007 |
Calcium signaling via phospholipase C is essential for proline accumulation upon ionic but not nonionic hyperosmotic stresses in Arabidopsis.
Topics: Arabidopsis; Boron Compounds; Calcium; Calcium Signaling; Estrenes; Indoles; Inositol 1,4,5-Trisphosphate; Molecular Sequence Data; Osmotic Pressure; Proline; Pyrimidinones; Pyrrolidinones; Seedlings; Sodium Chloride; Thiazoles; Type C Phospholipases; Water | 2007 |
Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes.
Topics: Action Potentials; Aniline Compounds; Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Differentiation; Cell Line; Embryonic Stem Cells; Endothelin-1; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Heart Rate; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Microscopy, Confocal; Myocytes, Cardiac; Nifedipine; Phenylephrine; Pyrrolidinones; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Time Factors; Type C Phospholipases; Xanthenes | 2007 |
Phospholipase C-gamma1 is required for the activation of store-operated Ca2+ channels in liver cells.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Diglycerides; Estrenes; Hepatocytes; Inositol 1,4,5-Trisphosphate; Membrane Glycoproteins; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C gamma; Pyrrolidinones; Rats; RNA, Small Interfering; Stromal Interaction Molecule 1; Thapsigargin; Transfection | 2007 |
Endoplasmic reticulum is a key organella in bradykinin-triggered ATP release from cultured smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Benzyl Compounds; Boron Compounds; Bradykinin; Calcium; Calcium Channel Blockers; Cells, Cultured; Colon; Egtazic Acid; Endoplasmic Reticulum; Estrenes; Ethylmaleimide; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Male; Microscopy, Confocal; Muscle, Smooth; Nifedipine; Pyrrolidinones; Receptor, Bradykinin B2; Rotenone; Thapsigargin; Thiazolidines; Verapamil | 2007 |
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell cycle.
Topics: Animals; Boron Compounds; Calcium; Cell Cycle; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Malaria; Melatonin; Plasmodium falciparum; Pyrrolidinones; Signal Transduction | 2007 |
Disruption of phospholipase Cgamma1 signalling attenuates cardiac tumor necrosis factor-alpha expression and improves myocardial function during endotoxemia.
Topics: Animals; Animals, Newborn; Cardiomyopathies; Cells, Cultured; Diglycerides; Disease Models, Animal; Endotoxemia; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Pyrrolidinones; RNA Interference; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2008 |
Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release.
Topics: Biosensing Techniques; Calcium; Cell Line; Cell Nucleus; Enzyme Inhibitors; Estrenes; Genes, Dominant; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Inositol 1,4,5-Trisphosphate; Microscopy, Fluorescence; Models, Biological; Nuclear Envelope; Pyrrolidinones; Type C Phospholipases | 2008 |
Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis.
Topics: Apoptosis; Cell Proliferation; DNA; Enzyme Activation; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neomycin; Phosphorylation; Propidium; Pyrrolidinones; Receptors, Calcium-Sensing; RNA, Small Interfering; Signal Transduction; Transfection | 2008 |
Contribution of the inositol 1,4,5-trisphosphate transduction cascade to the detection of "bitter" compounds in blowflies.
Topics: Animals; Diptera; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Pyrrolidinones; Sensitivity and Specificity; Signal Transduction; Taste | 2009 |
Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway.
Topics: Aniline Compounds; Calcium; Calcium Signaling; Estrenes; Fluorescent Dyes; Heterotrimeric GTP-Binding Proteins; Humans; Hypoxia; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intercellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Pulmonary Artery; Pyrrolidinones; Recombinant Proteins; RNA, Small Interfering; Type C Phospholipases; Tyrosine; Vasoconstriction; Xanthenes | 2009 |
Ins(1,4,5)P3 interacts with PIP2 to regulate activation of TRPC6/C7 channels by diacylglycerol in native vascular myocytes.
Topics: Animals; Axons; Blotting, Western; Diglycerides; Electrophysiology; Estrenes; Immunoprecipitation; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Mesenteric Arteries; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Phosphodiesterase Inhibitors; Portal Vein; Pyrrolidinones; Rabbits; TRPC Cation Channels | 2010 |
Light activation of the phosphoinositide cycle in intrinsically photosensitive chicken retinal ganglion cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Aniline Compounds; Animals; Calcium; Cells, Cultured; Chick Embryo; Dark Adaptation; Diacylglycerol Kinase; DNA Primers; Estrenes; Inositol 1,4,5-Trisphosphate; Light; Microscopy, Fluorescence; Phosphatidylinositols; Phosphodiesterase Inhibitors; Photic Stimulation; Pyrrolidinones; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rod Opsins; Type C Phospholipases; Xanthenes | 2010 |
Visualization of Ins(1,4,5)P3 dynamics in living cells: two distinct pathways for Ins(1,4,5)P3 generation following mechanical stimulation of HSY-EA1 cells.
Topics: Adenosine Triphosphate; Calcium; Cell Line; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Mechanotransduction, Cellular; Microscopy, Fluorescence; Phosphodiesterase Inhibitors; Pyrrolidinones; Signal Transduction; Suramin | 2010 |
Effect of [6]-shogaol on cytosolic Ca2+ levels and proliferation in human oral cancer cells (OC2).
Topics: Calcium; Calcium Channels, L-Type; Catechols; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Molecular Structure; Mouth Neoplasms; Phospholipase A2 Inhibitors; Protein Kinase C; Pyrrolidinones; Thapsigargin | 2010 |
Deuteration as a tool in investigating the role of protons in cell signaling.
Topics: Animals; Calcium; Calcium Signaling; Calorimetry; CHO Cells; Cricetinae; Cricetulus; Deuterium Exchange Measurement; Deuterium Oxide; Estrenes; Inositol 1,4,5-Trisphosphate; Methoxyhydroxyphenylglycol; Microscopy, Fluorescence; Phosphodiesterase Inhibitors; Protons; Pyrrolidinones; Receptors, Metabotropic Glutamate; Spectrometry, Fluorescence; Thermodynamics | 2011 |
Differential modulation of intracellular Ca2+ responses associated with calcium-sensing receptor activation in renal collecting duct cells.
Topics: Aniline Compounds; Animals; Calcium; Cell Line; Estrenes; GTP-Binding Protein alpha Subunits; Inositol 1,4,5-Trisphosphate; Kidney Tubules, Collecting; Mice; Phenethylamines; Propylamines; Pyrrolidinones; Receptors, Calcium-Sensing; rho-Associated Kinases; Type C Phospholipases | 2010 |
Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Line; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Estrenes; Gene Transfer Techniques; Glucose; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Insulin-Secreting Cells; Interleukin-6; Isoquinolines; Liver; Male; Mice; Neomycin; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Pyrrolidinones; RNA, Small Interfering; Signal Transduction; Sulfonamides; Type C Phospholipases | 2011 |
VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II.
Topics: Animals; Blotting, Western; Boron Compounds; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cattle; Cell Movement; Cell Proliferation; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Neovascularization, Physiologic; Oxazoles; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Retinal Vessels; Type C Phospholipases; Vascular Endothelial Growth Factor A | 2011 |
A fundamental role for NO-PLC signaling pathway in mediating intracellular Ca2+ oscillation in pancreatic acini.
Topics: Animals; Calcium; Carcinoma, Acinar Cell; Estrenes; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Oxazoles; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sincalide; Type C Phospholipases | 2011 |
Responses of round goby (Neogobius melanostomus) olfactory epithelium to steroids released by reproductive males.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cyclic AMP; Dihydrotestosterone; Enzyme Inhibitors; Estrenes; Etiocholanolone; Evoked Potentials; Female; Goldfish; Inositol 1,4,5-Trisphosphate; Male; Olfactory Mucosa; Perciformes; Pyrrolidinones; Reproduction; Second Messenger Systems; Sex Attractants; Smell; Species Specificity; Steroids; Type C Phospholipases | 2011 |
Sulfhydryl modification induces calcium entry through IP₃-sensitive store-operated pathway in activation-dependent human neutrophils.
Topics: Adult; Animals; Boron Compounds; Calcium; Calcium Signaling; Cell Movement; Estrenes; Ethylmaleimide; Humans; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nitroprusside; Pyrrolidinones; Rats; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Thapsigargin | 2011 |
Thiopental-induced insulin secretion via activation of IP3-sensitive calcium stores in rat pancreatic β-cells.
Topics: Anesthetics, Intravenous; Animals; Boron Compounds; Calcium; Estrenes; Glucose; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Insulin; Insulin Secretion; Insulin-Secreting Cells; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Pyrrolidinones; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Thiopental | 2012 |
Characteristics of spontaneous calcium oscillations in renal tubular epithelial cells.
Topics: Animals; Boron Compounds; Caffeine; Calcium; Calcium Signaling; Cell Line; Dogs; Epithelial Cells; Estrenes; Fura-2; Inositol 1,4,5-Trisphosphate; Kidney Tubules; Probenecid; Pyrrolidinones; Ryanodine | 2012 |
Effect of m-3m3FBS on Ca2+ handling and viability in OC2 human oral cancer cells.
Topics: Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Mouth Neoplasms; Phosphodiesterase Inhibitors; Pyrrolidinones; Sulfonamides | 2012 |
IP3-mediated octopamine-induced synaptic enhancement of crayfish LG neurons.
Topics: Adenosine; Animals; Astacoidea; Electric Stimulation; Enzyme Inhibitors; Estrenes; Female; Ganglia, Invertebrate; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Interneurons; Male; Octopamine; Pyrrolidinones; Sensation; Sensory Thresholds; Serotonin; Synaptic Potentials; Synaptic Transmission; Time Factors; Type C Phospholipases | 2012 |
Important role of PLC-γ1 in hypoxic increase in intracellular calcium in pulmonary arterial smooth muscle cells.
Topics: Animals; Boron Compounds; Calcium; Electron Transport Complex III; Estrenes; Gene Expression; Hypoxia; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lentivirus; Macrocyclic Compounds; Methacrylates; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxazoles; Phospholipase C gamma; Pulmonary Artery; Pyrrolidinones; Reactive Oxygen Species; RNA, Small Interfering; Thiazoles; Vasoconstriction | 2013 |
Juxtaglomerular cell CaSR stimulation decreases renin release via activation of the PLC/IP(3) pathway and the ryanodine receptor.
Topics: Animals; Calcimimetic Agents; Calcium; Cells, Cultured; Cinacalcet; Cyclic AMP; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate; Juxtaglomerular Apparatus; Mice; Models, Animal; Naphthalenes; Pertussis Toxin; Pyrrolidinones; Receptors, Calcium-Sensing; Renin; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Type C Phospholipases | 2013 |
Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway.
Topics: Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Estrenes; Inositol 1,4,5-Trisphosphate; Mice; Muscle Contraction; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2X1; Signal Transduction; Type C Phospholipases; Uridine Diphosphate; Urinary Bladder | 2013 |
Hydrogen sulfide regulates Ca(2+) homeostasis mediated by concomitantly produced nitric oxide via a novel synergistic pathway in exocrine pancreas.
Topics: Acinar Cells; Animals; Calcium; Calcium Signaling; Cells, Cultured; Cyclic GMP; Estrenes; Homeostasis; Hydrogen Sulfide; Inositol 1,4,5-Trisphosphate; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Pancreas, Exocrine; Pyrrolidinones; Rats; Rats, Wistar; Type C Phospholipases | 2014 |
Altered VEGF-stimulated Ca2+ signaling in part underlies pregnancy-adapted eNOS activity in UAEC.
Topics: Animals; Blotting, Western; Boron Compounds; Calcium; Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Estrenes; Female; Inositol 1,4,5-Trisphosphate; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Pregnancy; Pyrrolidinones; Sheep; Signal Transduction; Type C Phospholipases; Uterine Artery; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
The GPR55 agonist lysophosphatidylinositol relaxes rat mesenteric resistance artery and induces Ca(2+) release in rat mesenteric artery endothelial cells.
Topics: Animals; Calcium; Endothelial Cells; Estrenes; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Male; Mesenteric Arteries; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Type C Phospholipases; Vasodilator Agents | 2015 |