u 73122 has been researched along with epidermal growth factor in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 13 (72.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Logsdon, CD; Simeone, DM; Williams, JA; Yule, DI | 1 |
| Suzuki, K; Takahashi, K; Tsukatani, Y | 1 |
| Chen, P; Murphy-Ullrich, JE; Wells, A | 1 |
| Greenberg, NM; Kassis, J; Kim, HG; Lo, H; Moellinger, J; Wells, A | 1 |
| Alric, C; Bascands, JL; Girolami, JP; Pecher, C; Schanstra, JP | 1 |
| Ahn, YS; Choi, MU; Chung, KC; Eom, TY; Kwon, YK; Lee, SY; Min, DS; Sung, JY | 1 |
| Kassis, J; Radinsky, R; Wells, A | 1 |
| Brandt, BH; Dittmar, T; Husemann, A; Niggemann, B; Nofer, JR; Schewe, Y; Zänker, KS | 1 |
| Cranson, D; Trinkaus-Randall, V; Yang, L | 1 |
| Evdonin, AL; Margulis, BA; Medvedeva, ND; Tsupkina, NV | 1 |
| Cicchetti, G; Kwiatkowski, DJ; Lader, AS; Lee, JJ | 1 |
| Bai, X; Deng, F; Hua, L; Li, X; Lu, D; Luo, S; Su, Y; Zeng, W | 1 |
| Bae, YS; Bootman, MD; Byun, HM; Hong, JH; Jo, H; Kim, MS; Lee, SI; Moon, SJ; Roderick, HL; Seo, JT; Shin, DM | 1 |
| George, SP; Khurana, S; Tomar, A; Wang, Y | 1 |
| Aherne, W; Court, WJ; Eccles, SA; Jones, NP; Katan, M; Newbatt, YM; Raynaud, FI; Ruddle, R; Sheldrake, PW; Wilsher, NE | 1 |
| Armisén, R; Jørgensen, F; Leiva-Salcedo, E; Olivero, P; Sala, F; Simon, F; Stutzin, A; Varela, D | 1 |
| Selivanova, GV; Shemarova, IV; Vlasova, TD | 1 |
| Kim, MS; Kim, SH; Yang, SH | 1 |
18 other study(ies) available for u 73122 and epidermal growth factor
| Article | Year |
|---|---|
Ca2+ signaling through secretagogue and growth factor receptors on pancreatic AR42J cells.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Bombesin; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Carbachol; Cholecystokinin; Epidermal Growth Factor; Estrenes; Fibroblast Growth Factors; GTP-Binding Proteins; Hydrolysis; Inositol Phosphates; Neuropeptides; Neurotransmitter Agents; Pancreas; Pancreatic Neoplasms; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein-Tyrosine Kinases; Pyrrolidinones; Rats; Receptors, Neuropeptide; Substance P; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Inhibition of demecolcin-induced DNA synthesis by inhibitors of phospholipase C and protein kinase C.
Topics: Androstadienes; Breast; Cell Line; Cinnamates; Demecolcine; DNA; DNA Replication; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; ErbB Receptors; Estrenes; Female; Humans; Kinetics; Microtubules; Naphthalenes; Nitriles; Phosphorylation; Protein Kinase C; Pyrrolidinones; Type C Phospholipases; Tyrphostins; Wortmannin | 1996 |
A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motility.
Topics: 3T3 Cells; Actin Cytoskeleton; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Membrane; Cell Movement; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Estrenes; Gelsolin; Isoenzymes; Mice; Molecular Sequence Data; Mutation; Oligonucleotides, Antisense; Peptide Fragments; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphodiesterase Inhibitors; Phospholipase C gamma; Pyrrolidinones; Signal Transduction; Type C Phospholipases | 1996 |
A role for phospholipase C-gamma-mediated signaling in tumor cell invasion.
Topics: Adenocarcinoma; Animals; Autocrine Communication; Breast Neoplasms; Cell Line; Diffusion Chambers, Culture; Epidermal Growth Factor; ErbB Receptors; Estrenes; Female; Humans; Immunoblotting; Isoenzymes; Male; Mice; Neoplasm Invasiveness; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Prostatic Neoplasms; Pyrrolidinones; Quinazolines; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Type C Phospholipases | 1999 |
Bradykinin-induced inhibition of cell proliferation and tyrosine kinase activity in rat mesangial cells.
Topics: Angiotensin II; Animals; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Epidermal Growth Factor; Estrenes; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glomerular Mesangium; Insulin; Pertussis Toxin; Phospholipases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Pyrrolidinones; Rats; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Time Factors; Virulence Factors, Bordetella | 2000 |
Differential activation of phospholipases by mitogenic EGF and neurogenic PDGF in immortalized hippocampal stem cell lines.
Topics: Animals; Arachidonic Acid; Cell Differentiation; Cell Division; Cell Line, Transformed; Epidermal Growth Factor; Estrenes; Hippocampus; Neurites; Neurons; Phenotype; Phosphodiesterase Inhibitors; Phospholipase D; Phospholipases; Phospholipases A; Platelet-Derived Growth Factor; Pyrrolidinones; Stem Cells; Tritium; Type C Phospholipases | 2001 |
Motility is rate-limiting for invasion of bladder carcinoma cell lines.
Topics: Calpain; Cell Movement; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Estrenes; Humans; Isoenzymes; Neoplasm Invasiveness; Phospholipase C gamma; Pyrrolidinones; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Urinary Bladder Neoplasms | 2002 |
Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR.
Topics: Calcium; Cell Movement; Dimerization; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Estrenes; Humans; Isoenzymes; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Pyrrolidinones; Receptor, ErbB-2; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 2002 |
Cellular injury induces activation of MAPK via P2Y receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aniline Compounds; Calcium; Calcium Signaling; Cell Extracts; Cell Line, Transformed; Culture Media, Conditioned; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Estrenes; Humans; Immunohistochemistry; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Receptors, Purinergic P2; Type C Phospholipases; Uridine Triphosphate; Xanthenes | 2004 |
[Effect of EGF on the intracellular distribution of heat-shock proteins in A431 cells].
Topics: Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Estrenes; Fluorescent Antibody Technique; Heat-Shock Proteins; Hot Temperature; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Quinazolines; Time Factors; Type C Phospholipases; Tyrphostins; Vanadates | 2003 |
Mechanisms of gelsolin-dependent and -independent EGF-stimulated cell motility in a human lung epithelial cell line.
Topics: Antibodies, Monoclonal; Calcium; Cell Line; Cell Line, Tumor; Cell Movement; Chromones; Culture Media, Serum-Free; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Estrenes; Fibrinogen; Fibronectins; Gelsolin; Humans; Lung; Models, Biological; Morpholines; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Pyrrolidinones; Serum; Transfection; Type C Phospholipases | 2005 |
NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells.
Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Epidermal Growth Factor; Estrenes; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Humans; NF-kappa B; Phospholipase C gamma; Proline; Pyrrolidinones; Signal Transduction; Thiocarbamates | 2005 |
Critical role of phospholipase Cgamma1 in the generation of H2O2-evoked [Ca2+]i oscillations in cultured rat cortical astrocytes.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Estrenes; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Phospholipase C gamma; Pyrrolidinones; Rats; Rats, Wistar; Thapsigargin | 2006 |
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration.
Topics: Actins; Animals; Caco-2 Cells; Cell Membrane; Cell Movement; Dogs; Epidermal Growth Factor; Epithelial Cells; Estrenes; Fluorescence Resonance Energy Transfer; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Kidney; Mice; Microfilament Proteins; Mutation; Phospholipase C gamma; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Pyrrolidinones; RNA, Small Interfering; Signal Transduction; src Homology Domains; src-Family Kinases; Transfection; Tyrosine; Wound Healing | 2007 |
The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium.
Topics: Artifacts; Biological Assay; Calcium Signaling; Cell Line, Tumor; Culture Media; Drug Evaluation, Preclinical; Drug Stability; Enzyme Inhibitors; Epidermal Growth Factor; Estrenes; Glutamine; Glutathione; Half-Life; Humans; Protein Binding; Pyrrolidinones; Serum Albumin, Bovine; Time Factors; Type C Phospholipases | 2007 |
Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation.
Topics: Animals; Boron Compounds; Calcium Signaling; Cell Line, Tumor; Chloride Channels; Enzyme Activation; Epidermal Growth Factor; Estrenes; Genes, Dominant; Hydrogen Peroxide; Ion Channel Gating; Liver Neoplasms, Experimental; Mutant Proteins; Phospholipase C gamma; Phosphorylation; Pyrimidines; Pyrrolidinones; Rats; src-Family Kinases | 2007 |
[Changes in the DNA content in EGF-stimulated ciliate Tetrahymena pyriformis under effect of caffeine, KCl, and inhibitors of PLC and PKC].
Topics: Adaptation, Physiological; Animals; Benzophenanthridines; Caffeine; Calcium Signaling; Culture Media; DNA Replication; DNA, Protozoan; Epidermal Growth Factor; Estrenes; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Kinase C; Pyrrolidinones; Tetrahymena pyriformis; Type C Phospholipases | 2008 |
Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses altered epidermal growth factor-mediated Ca2+ response, which consequently enhances gefitinib sensitivity.
Topics: Antineoplastic Agents; Calcium Signaling; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Estrenes; Gefitinib; Humans; Lung Neoplasms; NFATC Transcription Factors; Pyrrolidinones; Type C Phospholipases | 2020 |