u 73122 has been researched along with bisindolylmaleimide i in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (7.14) | 18.2507 |
| 2000's | 39 (69.64) | 29.6817 |
| 2010's | 12 (21.43) | 24.3611 |
| 2020's | 1 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Eguchi, S; Inagami, T; Matsumoto, T; Motley, ED; Utsunomiya, H | 1 |
| Driessens, MH; Roos, E; Soede, RD; van Hulten, PE; van Rijthoven, EA | 1 |
| Liu, J; Marcus, DC; Scofield, MA; Shen, Z; Sunose, H | 1 |
| Bennett, T; Liu, J; Marcus, DC; Ryan, AF; Scofield, MA; Shen, Z; Sunose, H | 1 |
| Paolucci, L; Rozengurt, E; Sinnett-Smith, J | 1 |
| Hirai, SI; Ohno, S; Zhuang, S | 1 |
| Araki, H; Kawabata, A; Kawai, K; Kuroda, R; Kuroki, N; Nishikawa, H | 1 |
| Chen, PC; Cheng, JT; Liu, IM; Yen, ST | 1 |
| Bernard, C; Butlen, D; Ferrary, E; Teixeira, M | 1 |
| Bradley, ME; Hexum, TD; Zhang, P; Zheng, J | 1 |
| Chien, CS; Chiu, CT; Hsiao, LD; Lin, CC; Shyr, MH; Wang, CC; Yang, CM | 1 |
| Chang, LC; Wang, JP | 1 |
| Nakajima, Y; Nakanishi, S; Shinohara, Y | 1 |
| Cheng, JT; Kuo, DH; Lin, MT; Liu, IM | 1 |
| Aravamudan, B; Broadie, K | 1 |
| Barros, F; de la Pena, P; Dupuy, SG; Garcia-Manso, D; Giraldez, T; Gomez-Varela, D | 1 |
| Craig, BW; Fick, CA; Olesen, JB; Wright, DC | 1 |
| Amin, AR; Biswas, MH; Hamaguchi, M; Huang, P; Ichigotani, Y; Mon, NN; Oo, ML; Yuan, H | 1 |
| DiMattina, AJ; Holland, JA; Johnson, DK; O'Donnell, RW; Stone, RI; Ziegler, LM | 1 |
| Han, JS; Kim, DS; Kim, TW; Yoon, MS | 1 |
| Ito, S; Ohizumi, Y; Rohra, DK; Saito, SY; Yamakuni, T | 1 |
| Bustelo, XR; Caloca, MJ; Zugaza, JL | 1 |
| Bristulf, J; Owman, C; Sabirsh, A | 1 |
| Kuan, YH; Lin, CN; Lin, RH; Tsao, LT; Wang, JP | 1 |
| Cameron, P; Kanke, T; Macfarlane, SR; McKenzie, RC; Plevin, R; Sloss, CM | 1 |
| Fu, WM; Tang, CH; Yang, RS | 1 |
| Fujimoto, S; Imagawa, N; Kawakami-Honda, N; Nagai, K; Nagasawa, K | 1 |
| Chen, LW; Hsu, CM; Lin, MW | 1 |
| Ferjan, I; Stempelj, M | 1 |
| Greco, S; Marsigliante, S; Storelli, C | 1 |
| Fukamizu, A; Hashimoto, T; Imai, N; Ishida, J; Kihara, M; Kitamura, H; Toya, Y; Umemura, S; Yoshida, S | 1 |
| Calixto, JB; Motta, EM; Rae, GA | 1 |
| Gao, C; Gao, N; Hu, HZ; Liu, S; Wood, JD; Xia, Y | 1 |
| Akçit, F; Cağlar, S; Cetin, A; Ozturk, OH; Tokay, A; Yeşilkaya, A | 1 |
| Davies, AJ; Lacchini, AH; Mackintosh, D; Walker, AJ | 1 |
| Namiki, H; Takahashi, H | 1 |
| Horinouchi, T; Jinno, A; Kajita, E; Miwa, S; Miyake, Y; Nishimoto, A; Nishiya, T; Yorozu, S | 1 |
| Abdullah, HI; Ferreri, NR; McGiff, JC; Pedraza, PL | 2 |
| Cho, NJ; Kim, S; Park, YS; Shin, Y | 1 |
| Bai, GY; Kim, SH; Kim, SZ; Park, WH; Yuan, K | 1 |
| Honjo, H; Ito, S; Kamiya, K; Kume, H; Makino, Y; Oguma, T; Shimokata, K; Shiraki, A | 1 |
| Azuma, M; Matsuda, K; Nejigaki, Y; Shioda, S; Takahashi, A; Tanaka, M; Uchiyama, M | 1 |
| Hu, T; Liu, Z; Shen, X | 1 |
| Furukawa, Y; Kawano, Y; Narahara, H; Nasu, K | 1 |
| Jiang, X; Qin, Z; Tao, J; Wang, F; Wang, J; Zhang, L; Zhang, Y | 1 |
| Diéguez, G; Fernández, N; García-Villalón, AL; Monge, L | 1 |
| Kanno, T; Nishizaki, T | 1 |
| An, HJ; Ji, YG; Kim, OJ; Ko, T; Lee, DH | 1 |
| Chatelier, A; Constantin, B; Déliot, N; Harisseh, R; Magaud, C | 1 |
| Bhattacharyya, N; Collins, MT; Dunn, D; Foster, BL; Nociti, FH; Presland, RB; Somerman, MJ; Tran, AB; Wang, L | 1 |
| Lii, CK; Lin, BH; Tsai, MH; Wang, TS | 1 |
| Gillespie, DG; Jackson, EK; Zhu, X | 1 |
| Leoncini, G; Signorello, MG | 1 |
| Bouquier, N; Dadak, S; Fagni, L; Goyet, E; Levenes, C; Perroy, J | 1 |
| Alzugaray, ME; Gavazzi, MV; Ronderos, JR | 1 |
56 other study(ies) available for u 73122 and bisindolylmaleimide i
| Article | Year |
|---|---|
Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive t
Topics: Adenosine Triphosphate; Amino Acid Sequence; Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genistein; GTP-Binding Proteins; Imidazoles; Indoles; Isoflavones; Kinetics; Maleimides; Molecular Sequence Data; Muscle, Smooth, Vascular; Peptides; Pertussis Toxin; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Substrate Specificity; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Activation of G-proteins with AIF-4 induces LFA-1-mediated adhesion of T-cell hybridoma cells to ICAM-1 by signal pathways that differ from phorbol ester- and manganese-induced adhesion.
Topics: Aluminum Compounds; Androstadienes; Animals; Cell Adhesion; Enzyme Activation; Enzyme Inhibitors; Estrenes; Fluorides; Genistein; GTP-Binding Proteins; Humans; Hybridomas; Indoles; Intercellular Adhesion Molecule-1; Isoflavones; Lymphocyte Function-Associated Antigen-1; Maleimides; Manganese; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Wortmannin | 1997 |
P2U purinergic receptor inhibits apical IsK/KvLQT1 channel via protein kinase C in vestibular dark cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Calcium Channels; Cloning, Molecular; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Gerbillinae; Humans; In Vitro Techniques; Indoles; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Maleimides; Membrane Potentials; Molecular Sequence Data; Polymerase Chain Reaction; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyrrolidinones; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sequence Alignment; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vestibule, Labyrinth | 1997 |
Protein kinase C mediates P2U purinergic receptor inhibition of K+ channel in apical membrane of strial marginal cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gerbillinae; Indoles; Maleimides; Molecular Sequence Data; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Purinergic P2 Receptor Agonists; Pyrrolidinones; Rats; Receptors, Purinergic P2; Species Specificity; Stria Vascularis; Type C Phospholipases | 1998 |
Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway.
Topics: 3T3 Cells; Animals; Enzyme Activation; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Indoles; Lysophospholipids; Maleimides; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Pyrrolidinones; Rats; Virulence Factors, Bordetella | 2000 |
Hyperosmolality induces activation of cPKC and nPKC, a requirement for ERK1/2 activation in NIH/3T3 cells.
Topics: 3T3 Cells; Animals; Chromones; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Estrenes; Extracellular Space; Hypertonic Solutions; Indoles; Isoenzymes; Maleimides; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Osmolar Concentration; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyrrolidinones; Sodium Chloride; Type C Phospholipases; Water-Electrolyte Balance | 2000 |
Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle.
Topics: Androstadienes; Animals; Apamin; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Duodenum; Enzyme Inhibitors; Estrenes; Genistein; Glycolates; Imidazoles; Indoles; Maleimides; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Pyrrolidinones; Rats; Rats, Wistar; Receptor, PAR-1; Receptors, Thrombin; Sodium; Wortmannin | 2000 |
Role of alpha1A-adrenoceptor in the regulation of glucose uptake into white adipocyte of rats in vitro.
Topics: Adipocytes; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Biological Transport, Active; Chromones; Clonidine; Deoxyglucose; Dioxanes; Enzyme Inhibitors; Estrenes; Glucose; Glucose Transporter Type 4; Indoles; Male; Maleimides; Methoxamine; Monosaccharide Transport Proteins; Morpholines; Muscle Proteins; Phenanthridines; Phosphoinositide-3 Kinase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Type C Phospholipases | 2000 |
Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Colforsin; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoquinolines; Kinetics; Maleimides; Models, Biological; Phospholipases A; Purine Nucleotides; Pyrimidine Nucleotides; Pyrrolidinones; Rana ridibunda; Receptor Cross-Talk; Receptors, Purinergic P2; Semicircular Canals; Sulfonamides; Suramin; Uridine Triphosphate | 2001 |
ATP stimulated cyclic AMP formation in bovine chromaffin cells is enhanced by neuropeptide Y.
Topics: Adenosine Triphosphate; Animals; Cattle; Cells, Cultured; Chromaffin Cells; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Indoles; Maleimides; Neuropeptide Y; Peptides, Cyclic; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Mechanisms of thrombin-induced MAPK activation associated with cell proliferation in human cultured tracheal smooth muscle cells.
Topics: Androstadienes; Benzoquinones; Blotting, Western; Cell Division; Cells, Cultured; Chelating Agents; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Genistein; Humans; Indoles; Lactams, Macrocyclic; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Isoforms; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyrrolidinones; Quinones; ras Proteins; Rifabutin; Thrombin; Time Factors; Trachea; Transfection; Virulence Factors, Bordetella; Wortmannin | 2001 |
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin | 2001 |
Glutamate induces focal adhesion kinase tyrosine phosphorylation and actin rearrangement in heterologous mGluR1-expressing CHO cells via calcium/calmodulin signaling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Cytoskeleton; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Estrenes; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Glutamic Acid; Indoles; Kinetics; Maleimides; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transfection; Type C Phospholipases | 2001 |
Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro.
Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; beta-Endorphin; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Male; Maleimides; Phenanthridines; Phenylephrine; Phosphodiesterase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Type C Phospholipases | 2001 |
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism.
Topics: Acetylcysteine; Animals; Antibodies; Blotting, Western; Caenorhabditis elegans Proteins; Carbazoles; Carrier Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; Drosophila; Drosophila Proteins; Drug Interactions; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Helminth Proteins; Horseradish Peroxidase; Immunohistochemistry; Indoles; Insect Proteins; Maleimides; Microscopy, Confocal; Multienzyme Complexes; Mutation; Neomycin; Neuromuscular Junction; Oligopeptides; Phorbol Esters; Phospholipid Ethers; Presynaptic Terminals; Proteasome Endopeptidase Complex; Pyrroles; Pyrrolidinones; Synapses; Tumor Suppressor Proteins; Type C Phospholipases | 2003 |
Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cells, Cultured; Enzyme Inhibitors; ERG1 Potassium Channel; Estrenes; Ether-A-Go-Go Potassium Channels; Hydrolysis; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Membrane Potentials; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Phosphoprotein Phosphatases; Phosphorylation; Pituitary Gland, Anterior; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Pyridines; Pyrrolidinones; Rats; rho-Associated Kinases; Signal Transduction; Thyrotropin-Releasing Hormone | 2003 |
Evidence for the involvement of a phospholipase C--protein kinase C signaling pathway in insulin stimulated glucose transport in skeletal muscle.
Topics: Animals; Biological Transport, Active; Cytosol; Diglycerides; Enzyme Inhibitors; Estrenes; Glucose; Hypoglycemic Agents; Immunoblotting; Indoles; Insulin; Isoenzymes; Male; Maleimides; Muscle, Skeletal; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C beta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases | 2003 |
The PLC-PKC cascade is required for IL-1beta-dependent Erk and Akt activation: their role in proliferation.
Topics: Animals; Antigens, Differentiation; BALB 3T3 Cells; Cell Division; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Glycoproteins; Immunoblotting; Indoles; Interleukin-1; Maleimides; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Neural Cell Adhesion Molecule L1; Phospholipase C gamma; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinase C; Pyrrolidinones; Receptors, Immunologic; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Type C Phospholipases | 2003 |
Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein.
Topics: Arachidonic Acids; Cells, Cultured; Chromones; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Imidazoles; Indoles; Lipoproteins, LDL; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Morpholines; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phospholipases A; Protein Kinase C; Pyridines; Pyrrolidinones; Reactive Oxygen Species; Signal Transduction; src-Family Kinases; Type C Phospholipases; Umbilical Veins | 2003 |
Thyrotropin-releasing hormone increases phospholipase D activity through stimulation of protein kinase C in GH3 cells.
Topics: Animals; Calcium; Cell Line, Tumor; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoenzymes; Maleimides; Phospholipase D; Protein Kinase C; Protein Transport; Pyrroles; Pyrrolidinones; Rats; Thyrotropin-Releasing Hormone | 2004 |
Evidence for the involvement of protein kinase C in acidic pH-induced contraction in spontaneously hypertensive rat aorta.
Topics: Animals; Aorta, Thoracic; Bridged-Ring Compounds; Butadienes; Drug Synergism; Estrenes; Flavonoids; Hydrogen-Ion Concentration; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nitriles; Norbornanes; Phosphatidate Phosphatase; Phosphatidylinositol Diacylglycerol-Lyase; Potassium Chloride; Propranolol; Protein Kinase C; Pyrrolidinones; Rats; Rats, Inbred SHR; Thiocarbamates; Thiones; Type C Phospholipases; Tyrphostins | 2004 |
Inverted signaling hierarchy between RAS and RAC in T-lymphocytes.
Topics: Cell Cycle Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Estrenes; Guanine Nucleotide Exchange Factors; Humans; Indoles; Jurkat Cells; Maleimides; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Pyrrolidinones; rac1 GTP-Binding Protein; ras Proteins; Signal Transduction; T-Lymphocytes; Type C Phospholipases; Tyrosine | 2004 |
Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2.
Topics: Boron Compounds; Calcium; Calcium Channel Blockers; Cytosol; Dantrolene; Dose-Response Relationship, Drug; Estrenes; Fatty Alcohols; Glycols; HeLa Cells; Humans; Imidazoles; Indoles; Intracellular Space; Maleimides; Nickel; Nifedipine; Plasmids; Propranolol; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Leukotriene B4; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection | 2004 |
Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways.
Topics: Animals; Butadienes; Calcium; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; Immunoblotting; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2005 |
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; I-kappa B Kinase; Indoles; Keratinocytes; Maleimides; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotides; Phosphodiesterase Inhibitors; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyrrolidinones; Receptor, PAR-2; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases | 2005 |
Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts.
Topics: Animals; Blotting, Western; Bone and Bones; Bone Density; Calcium; Cell Membrane; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Fibronectins; Genes, Dominant; Genes, Reporter; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Indoles; Integrin alpha5; Integrin beta1; Integrins; Maleimides; Microscopy, Fluorescence; Mutation; Oligonucleotides; Oligonucleotides, Antisense; Osteoblasts; Promoter Regions, Genetic; Protein Isoforms; Protein Kinase C; Pyrimidines; Pyrrolidinones; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; src-Family Kinases; Transfection; Type C Phospholipases; Up-Regulation | 2005 |
Protein kinase C-independent pathway for NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes by cytochalasin D.
Topics: Androstadienes; Animals; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Ethanol; Female; Guinea Pigs; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxygen; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase D; Phosphoproteins; Protein Kinase C; Protein Transport; Pyrrolidinones; Signal Transduction; Subcellular Fractions; Wortmannin | 2005 |
Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils.
Topics: Androstadienes; Aristolochic Acids; Calcium; Calcium Channel Blockers; Calcium Channels; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Indoles; Maleimides; Models, Biological; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Isoforms; Protein Kinase C; Pyrrolidinones; Type C Phospholipases; Wortmannin | 2005 |
Signaling pathway in nerve growth factor induced histamine release from rat mast cells.
Topics: Analysis of Variance; Androstadienes; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Flavonoids; Histamine; Imidazoles; Indoles; Male; Maleimides; Mast Cells; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tyrosine; Wortmannin | 2005 |
Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin.
Topics: Analysis of Variance; Biological Transport; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chromones; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Flavonoids; Humans; Immunoblotting; Indoles; Kallidin; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyrrolidinones; Stimulation, Chemical; Tetrahydroisoquinolines | 2006 |
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells.
Topics: Adipokines; Animals; Aorta, Thoracic; Apelin; Apelin Receptors; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; In Vitro Techniques; Indoles; Intercellular Signaling Peptides and Proteins; Ion Exchange; Male; Maleimides; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Pertussis Toxin; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2006 |
Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases.
Topics: Animals; Endothelin-1; Enzyme Inhibitors; Estrenes; Hyperalgesia; Imidazoles; Indoles; Injections, Intradermal; Male; Maleimides; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Reaction Time; Signal Transduction; Type C Phospholipases | 2006 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Farnesol; Indoles; Losartan; Male; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Pyrrolidinones; ras Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Salicylates; Time Factors; Type C Phospholipases | 2007 |
Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation.
Topics: Animals; beta-Glucans; Carbazoles; Estrenes; Extracellular Signal-Regulated MAP Kinases; Glucans; Hemocytes; Hydrogen Peroxide; Indoles; Lymnaea; Maleimides; Phosphatidylinositol 3-Kinases; Phospholipid Ethers; Phosphorylation; Polysaccharides; Protein Kinase C; Protein Kinase Inhibitors; Pyrrolidinones; Reactive Oxygen Species; Signal Transduction | 2006 |
Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carbazoles; Cell Membrane; Chlorocebus aethiops; COS Cells; Diglycerides; Estrenes; HeLa Cells; HL-60 Cells; Humans; Indoles; Maleimides; Membranes; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; Pyrrolidinones; Staurosporine | 2007 |
Characterization of noradrenaline-induced increases in intracellular Ca2+ levels in Chinese hamster ovary cells stably expressing human alpha1A-adrenoceptor.
Topics: Acetamides; Animals; Calcium; Calcium Channels, L-Type; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Estrenes; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Imidazoles; Indoles; Intracellular Fluid; Isoquinolines; Lanthanum; Maleimides; Models, Biological; Nifedipine; Norepinephrine; Peptides, Cyclic; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Receptors, Adrenergic, alpha-1; Thiourea; Transfection | 2007 |
CaR activation increases TNF production by mTAL cells via a Gi-dependent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Calcineurin; Calcium; Cells, Cultured; Enzyme Inhibitors; Estrenes; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Imines; Indoles; Inositol Phosphates; Kidney Medulla; Male; Maleimides; Models, Biological; NFATC Transcription Factors; Pertussis Toxin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2008 |
Regulation of ERK1/2 by the C. elegans muscarinic acetylcholine receptor GAR-3 in Chinese hamster ovary cells.
Topics: Alternative Splicing; Animals; Atropine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carbachol; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Estrenes; Indoles; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscarinic Agonists; Muscarinic Antagonists; Protein Isoforms; Protein Kinase C; Pyrrolidinones; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Type C Phospholipases | 2008 |
Attenuation of hypoosmotic stress-induced ANP secretion via I(Cl,swell) in renal hypertensive rat atria.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Atrial Natriuretic Factor; Cardiomegaly; Chloride Channels; Estrenes; Extracellular Fluid; Genistein; Heart Atria; Hypertension, Renal; Indoles; Maleimides; Okadaic Acid; Osmotic Pressure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Staurosporine; Tamoxifen; Vanadates | 2008 |
Calcium-sensing receptor signaling pathways in medullary thick ascending limb cells mediate COX-2-derived PGE2 production: functional significance.
Topics: Animals; Calcineurin; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Estrenes; GTP-Binding Protein alpha Subunits, Gq-G11; Indoles; Loop of Henle; Male; Maleimides; Ouabain; Oxygen Consumption; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Signal Transduction; Tumor Necrosis Factor-alpha | 2008 |
Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Bridged-Ring Compounds; Calcium Channel Blockers; Calcium Signaling; Diltiazem; Dinoprost; Dioxanes; Enzyme Inhibitors; Estrenes; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Norbornanes; Pyridines; Pyrrolidinones; Receptors, Thromboxane A2, Prostaglandin H2; rho-Associated Kinases; Signal Transduction; Thiocarbamates; Thiones; Trachea; Type C Phospholipases; Vasoconstrictor Agents; Verapamil | 2009 |
Pituitary adenylate cyclase-activating polypeptide induces somatolactin release from cultured goldfish pituitary cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calmodulin; Cells, Cultured; Enzyme Inhibitors; Estrenes; Female; Fish Proteins; Glycoproteins; Goldfish; Growth Substances; Imidazoles; Imines; Immunoblotting; Indoles; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Maleimides; Phosphoinositide Phospholipase C; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Pituitary Hormones; Protein Kinase C; Pyrrolidinones; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Signal Transduction; Sulfonamides; Vasoactive Intestinal Peptide | 2009 |
Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst.
Topics: 1-Butanol; Calcium; Cells, Cultured; Diglycerides; Enzyme Inhibitors; Estrenes; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphodiesterase Inhibitors; Phospholipase D; Protein Kinase C; Protein Transport; Pyrrolidinones; Respiratory Burst; Tetradecanoylphorbol Acetate | 2011 |
Thrombin-induced chemokine production in endometrial stromal cells.
Topics: Adult; Amino Acid Chloromethyl Ketones; Boron Compounds; Butadienes; Cells, Cultured; Chemokine CCL2; Chemokine CXCL1; Endometrium; Estrenes; Female; Humans; Indoles; Interleukin-8; Maleimides; Nitriles; Pyrrolidinones; Receptor, PAR-1; Stromal Cells; Thrombin | 2011 |
Activation of M3 muscarinic receptors inhibits T-type Ca(2+) channel currents via pertussis toxin-sensitive novel protein kinase C pathway in small dorsal root ganglion neurons.
Topics: Animals; Calcium Channels, T-Type; Calcium Signaling; Cholera Toxin; Cobra Neurotoxin Proteins; Estrenes; Ganglia, Spinal; Indoles; Maleimides; Mice; Mice, Inbred ICR; Muscarinic Antagonists; Neurons; Pain Measurement; Pertussis Toxin; Piperidines; Protein Kinase C; Pyrrolidinones; Receptor, Muscarinic M3; Type C Phospholipases | 2011 |
Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Androstadienes; Animals; Coronary Vessels; Dinucleoside Phosphates; Endothelin-1; Estrenes; Glyburide; Heart; In Vitro Techniques; Indoles; Isatin; Isoquinolines; Male; Maleimides; NG-Nitroarginine Methyl Ester; Perfusion; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rest; Sulfonamides; Triazines; Vasoconstriction; Wortmannin | 2011 |
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Lysophospholipids; Male; Maleimides; Mossy Fibers, Hippocampal; Neurons; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; Suramin; Thiazoles | 2011 |
P2Y receptors regulate proliferation of human pancreatic duct epithelial cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blotting, Western; Boron Compounds; Cell Line, Tumor; Cell Proliferation; Deoxyadenine Nucleotides; Epithelial Cells; Estrenes; Gene Expression Regulation, Neoplastic; Humans; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Isothiocyanates; Maleimides; Pancreatic Ducts; Protein Kinase C; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiourea; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate | 2012 |
Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation.
Topics: Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Cells, Cultured; Estrenes; Gadolinium; Gene Expression; Humans; Imidazoles; Indoles; Maleimides; Membrane Proteins; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Dystrophy, Duchenne; Neoplasm Proteins; Nifedipine; ORAI1 Protein; Patch-Clamp Techniques; Primary Cell Culture; Protein Kinase C; Pyrrolidinones; Sarcoplasmic Reticulum; Stromal Interaction Molecule 1; TRPC Cation Channels; TRPV Cation Channels; Type C Phospholipases | 2013 |
Vitamin D represses dentin matrix protein 1 in cementoblasts and osteocytes.
Topics: Animals; Calcitriol; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dental Cementum; Dose-Response Relationship, Drug; Down-Regulation; Estrenes; Extracellular Matrix Proteins; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Flavonoids; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Indoles; Maleimides; MAP Kinase Signaling System; Mice; Osteocytes; Protein Kinase C; Pyrrolidinones; Receptors, Calcitriol; Type C Phospholipases; Vitamins; Vorinostat | 2014 |
IP3 and calcium signaling involved in the reorganization of the actin cytoskeleton and cell rounding induced by cigarette smoke extract in human endothelial cells.
Topics: Acetylcysteine; Actin Cytoskeleton; Antioxidants; Calcium Signaling; Cell Line; Chelating Agents; Endothelial Cells; Estrenes; Glutathione; Humans; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Maleimides; Microscopy, Fluorescence; Nicotiana; Nitrendipine; Oxazoles; Oxidative Stress; Protein Kinase C; Pyrrolidinones; Reactive Oxygen Species; Smoke; Type C Phospholipases | 2016 |
NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4.
Topics: Angiotensin II; Animals; Cell Proliferation; Collagen; Dipeptidyl-Peptidase IV Inhibitors; Estrenes; Fibroblasts; GTP-Binding Proteins; Hypertension; Indoles; Maleimides; Myocardium; Neuropeptide Y; Peptide Fragments; Peptide YY; Pertussis Toxin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors for Activated C Kinase; Signal Transduction; Sitagliptin Phosphate; Type C Phospholipases | 2015 |
Regulation of cAMP Intracellular Levels in Human Platelets Stimulated by 2-Arachidonoylglycerol.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cannabinoid Receptor Agonists; Cells, Cultured; Chromones; Cyclic AMP; Dose-Response Relationship, Drug; Endocannabinoids; Estrenes; Fatty Acids, Unsaturated; Glycerides; Humans; Hydrazines; Immunoblotting; Indoles; Intracellular Space; Maleimides; Milrinone; Morpholines; Phosphatidylinositol 3-Kinases; Phosphodiesterase 3 Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Protein Kinase C; Pyrrolidinones; Receptors, Thromboxane; Type C Phospholipases | 2016 |
mGlu1 receptor canonical signaling pathway contributes to the opening of the orphan GluD2 receptor.
Topics: Animals; Cerebellum; Estrenes; HEK293 Cells; Humans; Indoles; Maleimides; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Pyrrolidinones; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Signal Transduction | 2017 |
G protein-coupled receptor signal transduction and Ca
Topics: Animals; Calcium; Calcium Signaling; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Hydra; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Insect Hormones; Maleimides; Melitten; Neuropeptides; Orexins; Protein Kinase C; Pyrrolidinones; Receptors, G-Protein-Coupled; Type C Phospholipases | 2021 |