u 69593 has been researched along with naltrindole in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (43.48) | 18.2507 |
| 2000's | 12 (52.17) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, GI; Breder, CD; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yasuda, K | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Grundt, P; Husbands, SM; Jales, AR; Lewis, JW; Traynor, JR | 1 |
| Anzini, M; Azzolina, O; Braile, C; Canullo, L; Cappelli, A; Collina, S; De Benedetti, PG; Galeotti, N; Gallelli, A; Ghelardini, C; Menziani, MC; Rizzo, M; Sbacchi, M; Vomero, S | 1 |
| Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE | 1 |
| Aoki, T; Endo, T; Fujii, H; Hasebe, K; Ito, T; Kamei, J; Kawai, K; Kawamura, K; Maeda, M; Nagase, H; Nakajima, M; Sakami, S; Ueno, S | 1 |
| Búzás, B; Cox, BM; Izenwasser, S | 1 |
| Bell, GI; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yano, H | 1 |
| Fukushima, N; Misu, Y; Miyamae, T; Ueda, H | 1 |
| Desmeules, JA; Guilbaud, G; Kayser, V | 1 |
| Borsodi, A; Hosztafi, S; Nevin, ST; Rónai, AZ; Spetea, M; Tóth, G | 1 |
| Foxx-Orenstein, AE; Grider, JR; Jin, JG | 1 |
| Dersch, C; Kubota, H; McCullough, K; Pinto, J; Rice, KC; Rothman, RB | 1 |
| Minami, M; Nakagawa, T; Ozawa, T; Satoh, M; Watanabe, T | 1 |
| Bidlack, JM; Cioffi, CL; Cohen, DJ; Colasurdo, AM; Duan, W; Wentland, MP; Xu, G; Ye, Y | 1 |
| Balboni, G; Bryant, SD; Butterworth, J; Guerrini, R; Labarre, M; Lazarus, LH; Payza, K; Salvadori, S; Schmidhammer, H; St-Onge, S | 1 |
| Husbands, SM; Jales, AR; Lewis, JW | 1 |
| Ananthan, S; Lu, YF; Rice, KC; Rothman, RB; Xu, H | 1 |
| Brown, DR; Townsend, D | 1 |
| Folk, JE; Linsenmayer, DC; Negus, SS; Rice, KC; Stevenson, GW | 1 |
| Bart, G; Bidlack, JM; Borg, L; Ho, A; Kreek, MJ; Schluger, JH | 1 |
| Fantegrossi, WE; Koreeda, M; Kugle, KM; Valdes, LJ; Woods, JH | 1 |
| Chang, XM; Fang, Q; Han, ZL; Li, N; Li, XH; Pan, JX; Tang, HH; Wang, P; Wang, R; Wang, ZL; Zheng, T | 1 |
23 other study(ies) available for u 69593 and naltrindole
| Article | Year |
|---|---|
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Somatostatin; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution | 1993 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
14-amino, 14-alkylamino, and 14-acylamino analogs of oxymorphindole. Differential effects on opioid receptor binding and functional profiles.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; CHO Cells; Cricetinae; Morpholines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship | 2003 |
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.
Topics: Amino Acid Sequence; Analgesics; Animals; Avoidance Learning; Benzodiazepines; Cell Line; Cricetinae; Guinea Pigs; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Nootropic Agents; Pain Threshold; Radioligand Assay; Receptors, Opioid, kappa; Regression Analysis; Sequence Homology, Amino Acid; Stereoisomerism; Structure-Activity Relationship | 2003 |
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 2004 |
Structure-antitussive activity relationships of naltrindole derivatives. Identification of novel and potent antitussive agents.
Topics: Alkylation; Animals; Antitussive Agents; Capsaicin; CHO Cells; Cough; Cricetinae; Cricetulus; Male; Mice; Molecular Structure; Naltrexone; Rats; Structure-Activity Relationship | 2008 |
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin | 1993 |
Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Base Sequence; Benzeneacetamides; Binding Sites; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Colforsin; Cyclic AMP; Enkephalin, Leucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Naltrexone; Oligodeoxyribonucleotides; Protein Structure, Secondary; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Recombinant Fusion Proteins; Recombinant Proteins; Transfection | 1994 |
Delta opioid receptor mediates phospholipase C activation via Gi in Xenopus oocytes.
Topics: Analgesics; Animals; Benzeneacetamides; Electric Conductivity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Enzyme Activation; Female; Gene Expression; GTP-Binding Proteins; Membrane Potentials; Mice; Naltrexone; Narcotic Antagonists; Oocytes; Pyrrolidines; Receptors, Opioid, delta; Type C Phospholipases; Xenopus laevis | 1993 |
Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain.
Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Disease Models, Animal; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vocalization, Animal | 1993 |
Affinity profiles of novel delta-receptor selective benzofuran derivatives of non-peptide opioids.
Topics: Animals; Benzeneacetamides; Benzofurans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Naltrexone; Oligopeptides; Oxycodone; Oxymorphone; Pyrrolidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tritium | 1998 |
5-HT4 receptor agonists and delta-opioid receptor antagonists act synergistically to stimulate colonic propulsion.
Topics: Animals; Benzeneacetamides; Colon; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Peptide Fragments; Peristalsis; Pyrrolidines; Receptors, Opioid, delta; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Somatostatin | 1998 |
Synthesis and biological activity of 3-substituted 3-desoxynaltrindole derivatives.
Topics: Animals; Benzeneacetamides; Binding, Competitive; Brain; Cell Membrane; Drug Design; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Molecular Structure; Naltrexone; Narcotic Antagonists; Pyrrolidines; Rats; Receptors, Opioid, delta; Structure-Activity Relationship | 1998 |
[A molecular mechanism for supersensitization of adenylyl cyclase system in cloned opioid receptor-transfected cells following sustained opioid treatment].
Topics: Adenylyl Cyclases; Analgesics; Animals; Atropine; Benzeneacetamides; Carbachol; CHO Cells; Clone Cells; Cricetinae; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP Phosphohydrolases; Morphine; Muscarinic Agonists; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Transfection | 1998 |
8-Aminocyclazocine analogues: synthesis and structure-activity relationships.
Topics: Analgesics; Animals; Benzeneacetamides; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Molecular Structure; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship | 2000 |
Inverse agonism by Dmt-Tic analogues and HS 378, a naltrindole analogue.
Topics: Benzamides; Benzeneacetamides; Binding, Competitive; Cell Line; Cell Membrane; Dipeptides; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoquinolines; Naltrexone; Narcotic Antagonists; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Tetrahydroisoquinolines | 2000 |
Selective kappa-opioid antagonists related to naltrindole. Effect of side-chain spacer in the 5'-amidinoalkyl series.
Topics: Amidines; Animals; Benzeneacetamides; Binding, Competitive; Brain; Cell Membrane; Drug Design; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Guinea Pigs; Indicators and Reagents; Kinetics; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Structure-Activity Relationship | 2000 |
SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Benzeneacetamides; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Iodine Radioisotopes; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Piperazines; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Tritium | 2001 |
Predominance of delta-opioid-binding sites in the porcine enteric nervous system.
Topics: Animals; Benzeneacetamides; Binding Sites; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enteric Nervous System; Female; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Myenteric Plexus; Naltrexone; Narcotic Antagonists; Neurons; Pyrrolidines; Radioligand Assay; Radiopharmaceuticals; Receptors, Opioid, delta; Saxitoxin; Swine | 2002 |
Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception.
Topics: Analgesics, Opioid; Animals; Benzamides; Benzeneacetamides; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Pain; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule | 2003 |
Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity?
Topics: Adolescent; Adult; Analgesics, Opioid; Animals; Benzeneacetamides; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Estradiol; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Naltrexone; Narcotic Antagonists; Prolactin; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2005 |
Kappa-opioid receptor-mediated effects of the plant-derived hallucinogen, salvinorin A, on inverted screen performance in the mouse.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzeneacetamides; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Psychotropic Drugs; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil | 2005 |
Opposite effects of neuropeptide FF on central antinociception induced by endomorphin-1 and endomorphin-2 in mice.
Topics: Adamantane; Animals; Benzeneacetamides; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Naltrexone; Nociception; Oligopeptides; Pyrrolidines | 2014 |