u 69593 has been researched along with gr 89696 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Englberger, W; Geiger, C; Lehmkuhl, K; Schepmann, D; Wünsch, B; Zelenka, C | 1 |
| Headley, PM; Herrero, JF | 1 |
| Caudle, RM; Dubner, R; Ho, J; Mannes, AJ | 1 |
| Caudle, RM; Iadarola, MJ; Mannes, AJ | 1 |
| Dannals, RF; Finley, P; Mathews, WB; Musachio, JL; Ravert, HT; Scheffel, U | 1 |
| Butelman, ER; Ko, MC; Kreek, MJ; Traynor, JR; Vivian, JA; Woods, JH | 1 |
| Grau, JW; Maultsby, ML; Puga, DA; Washburn, SN | 1 |
| Bertoglio, LJ; Bicca, MA; Giachero, M; Linartevichi, VF; Monteiro de Lima, TC; Vanz, F | 1 |
8 other study(ies) available for u 69593 and gr 89696
| Article | Year |
|---|---|
Conformationally constrained kappa receptor agonists: stereoselective synthesis and pharmacological evaluation of 6,8-diazabicyclo[3.2.2]nonane derivatives.
Topics: Animals; Azabicyclo Compounds; Cell Line; Guinea Pigs; Humans; In Vitro Techniques; Molecular Conformation; Radioligand Assay; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship | 2010 |
Functional evidence for multiple receptor activation by kappa-ligands in the inhibition of spinal nociceptive reflexes in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Anticonvulsants; Benzeneacetamides; Benzofurans; Blood Pressure; Decerebrate State; Male; Naloxone; Nociceptors; Piperazines; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord; Thiophenes | 1993 |
Putative kappa-2 opioid agonists are antihyperalgesic in a rat model of inflammation.
Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Male; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1997 |
GR89,696 is a kappa-2 opioid receptor agonist and a kappa-1 opioid receptor antagonist in the guinea pig hippocampus.
Topics: Animals; Benzeneacetamides; Benzomorphans; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Piperazines; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1997 |
[11C]-methyl 4-[(3,4-dichlorophenyl)acetyl]-3-[(1-pyrrolidinyl)-methyl]-1- piperazinecarboxylate ([11C]GR89696): synthesis and in vivo binding to kappa opiate receptors.
Topics: Animals; Benzeneacetamides; Binding, Competitive; Brain; Carbon Radioisotopes; Dopamine Antagonists; Isotope Labeling; Ketanserin; Mice; Piperazines; Pyrrolidines; Radiopharmaceuticals; Receptors, Opioid, kappa; Serotonin Antagonists; Spiperone; Tissue Distribution | 1999 |
GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzeneacetamides; Cerebral Cortex; Discrimination, Psychological; Diuresis; Ethylketocyclazocine; Female; Guanosine 5'-O-(3-Thiotriphosphate); Macaca mulatta; Male; Membranes; Muscle Relaxation; Naltrexone; Pain Measurement; Piperazines; Prolactin; Pyrrolidines; Radioligand Assay; Receptors, Opioid, kappa; Respiratory Mechanics | 2001 |
Opioid regulation of spinal cord plasticity: evidence the kappa-2 opioid receptor agonist GR89696 inhibits learning within the rat spinal cord.
Topics: Adaptation, Physiological; Animals; Association Learning; Benzeneacetamides; Conditioning, Operant; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Neuronal Plasticity; Neurons; Neurotransmitter Agents; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae | 2008 |
Role of dorsal hippocampus κ opioid receptors in contextual aversive memory consolidation in rats.
Topics: Analgesics, Opioid; Animals; Association; Avoidance Learning; Benzeneacetamides; Conditioning, Psychological; Electroshock; Freezing Reaction, Cataleptic; Hippocampus; Male; Memory Consolidation; Naltrexone; Narcotic Antagonists; Piperazines; Psychotropic Drugs; Pyrrolidines; Random Allocation; Rats, Wistar; Receptors, Opioid, kappa | 2018 |